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1. Published Projects | SRDR
   srdrplus.ahrq.gov/published_projects?page=30
   June 27, 2021 - conditions (chronic low back pain, chronic neck pain, osteoarthritis of the knee, hip, or hand, fibromyalgia … Except for spinal manipulation, these interventions also improved pain. … Exercise was also associated with moderate improvement in pain (SOE: Low). … Exercise (SOE: Moderate) and CBT improved pain slightly and tai chi and qigong (SOE: Low) improved pain … for specific chronic pain conditions.

2. Published Projects | SRDR
   srdrplus.ahrq.gov/published_projects?page=23
   June 27, 2021 - conditions (chronic low back pain; chronic neck pain; osteoarthritis of the knee, hip, or hand; fibromyalgia … Effect sizes were generally small for function and pain. … improved function and pain. … Osteoarthritis pain: Exercise resulted in small improvements in function and pain at short-term(SOE: … beyond the course of therapy for specific chronic pain conditions.

3. Published Projects | SRDR
   srdrplus.ahrq.gov/published_projects?page=14
   June 27, 2022 - Recently Published Projects Search for more Projects Published on June 27, 2022 Acute Pain Updates 20 … : A Systematic Review (https://effectivehealthcare.ahrq.gov/products/treatments-acute-pain/research). … (low back pain, neck pain, other musculoskeletal pain, neuropathic pain, postoperative pain [excluding … inpatient management of pain after major surgical procedures], dental pain, pain due to kidney stones … , and pain due to sickle cell disease).

4. Published Projects | SRDR
   srdrplus.ahrq.gov/published_projects?page=12
   October 06, 2022 - However, given the persistence of chronic pain, understanding whether the benefits are durable would … Optimal pain management should address biopsychosocial aspects of pain. The U.S. … treatment, particularly through formal pain management programs. … of pain. … Todd Graham Pain Management Study and was sponsored by CMS.

5. Published Projects | SRDR
   srdrplus.ahrq.gov/published_projects?page=13
   September 14, 2022 - : https://effectivehealthcare.ahrq.gov/products/opioids-chronic-pain/research). … for outcomes related to pain, function, and quality of life after short-term treatment duration (3 to … In patients with chronic pain, what is the comparative effectiveness of nonopioid pharmacologic agents … compared to other nonopioid pharmacologic agents for outcomes related to pain, function, and quality … How do harms vary depending on: (1) the specific type or cause of pain, (2) patient demographics, (3)

6. Published Projects | SRDR
   srdrplus.ahrq.gov/published_projects?page=45
   June 23, 2021 - Low back pain is common and many pharmacological and nonpharmacological therapies are available. … 10-point NRS for pain). … on pain but no effects on function, and fewer studies measured function than pain. … Effects on function were generally smaller than effects on pain. … , and effectiveness on outcomes other than pain and function.

7. Published Projects | SRDR
   srdrplus.ahrq.gov/published_projects?page=16
   July 29, 2022 - November 29, 2021 Living Systematic Review on Cannabis and Other Plant-Based Treatments for Chronic Pain … Prioritized outcomes included pain, overall function, and adverse events. … Studies were primarily short-term, and 75 percent enrolled patients with a variety of neuropathic pain … in sedation, and a large increase in nausea (pain: 6 RCTs, N=390 to 10 scale, MD −1.15, 95% CI −1.99 … We observed a moderate improvement in pain severity when combining all studies of high-THC to CBD (8

8. Published Projects | SRDR
   srdrplus.ahrq.gov/published_projects?page=17
   November 22, 2023 - for patients, implementation of an opioid safety initiative, provision of patient information and pain … Vertebroplasty (13 trials) is probably more effective at reducing pain and improving function in older … (>65 years of age) patients, but benefits are small (less than one point on a 10 point pain scale). … (2 trials) is probably more effective for pain and function versus sham at 1 and 3 months (moderate … compression fractures; benefits are small but similar to other therapies recommended for pain.

9. Published Projects | SRDR
   srdrplus.ahrq.gov/published_projects?page=47
   June 23, 2021 - READ MORE Published on June 23, 2021 Pain Management Injection Therapies for Low-back Pain [Entered … Low back pain is common and injections with corticosteroids are a frequently used treatment option. … , or chronic postsurgical back pain that compared effectiveness or harms of epidural, facet joint, or … (SOE: low), but showed no differences in pain, function, or likelihood of surgery. … and that facet joint corticosteroid injections are not effective for presumed facet joint pain.

10. Published Projects | SRDR
    srdrplus.ahrq.gov/published_projects?page=4
    October 12, 2023 - becomes more prevalent with age and is managed with surgical and nonoperative treatments to alleviate pain … single-level disease, there were no important differences between cervical arthroplasty and ACDF in pain … In patients with 2-level disease, pain, function and likelihood of reoperation at the index level were … Anterior versus posterior approach: There was no difference between these approaches in pain, function … standalone cage versus plate and cage; there were no differences between treatments in postoperative arm pain

11. Published Projects | SRDR
    srdrplus.ahrq.gov/published_projects?page=26
    June 27, 2021 - for more Projects Published on June 27, 2021 Comparative Effectiveness of Analgesics to Reduce Acute Pain … We defined the following as clinically important differences: 2 points on a 0 to 10 pain scale, time … As initial analgesics, we found no evidence of a clinically important difference in the change of pain … Combined administration of an opioid and ketamine may reduce acute pain more than an opioid alone but … acute pain relief than giving additional morphine, although comparative harms are uncertain.

12. Published Projects | SRDR
    srdrplus.ahrq.gov/published_projects?page=22
    June 27, 2021 - READ MORE Published on June 27, 2021 Nonopioid Pharmacologic Treatments for Chronic Pain 180 Citations … comparative effectiveness of nonopioid pharmacologic agents in patients with specific types of chronic pain … , considering the effects of on pain, function, quality of life, and adverse events.

13. Published Projects | SRDR
    srdrplus.ahrq.gov/published_projects?page=19
    June 27, 2021 - READ MORE Published on June 27, 2021 Treatments for Acute Pain: A Systematic Review 190 Citations • … , including effects on pain, function, quality of life, adverse events, and long-term use of opioids. … Compared with placebo, triptans resolved pain at 2 hours and 1 day, and increased the risk of mild and … Compared with placebo, NSAIDs probably resolved pain at 2 hours and 1 day, and increased the risk of … Lasmiditan (the first approved 5-HT1F receptor agonist) restored function at 2 hours and resolved pain

14. Published Projects | SRDR
    srdrplus.ahrq.gov/published_projects?page=49
    June 23, 2021 - Pain outcomes improved for mothers of frenotomized infants compared with control in one study of 6-day … number of comparative studies and participants, the SOE is low for an immediate reduction in nipple pain … for minor and short-term bleeding following surgery and insufficient for other harms (reoperation, pain … be associated with improvements in breastfeeding as reported by mothers, and potentially in nipple pain

15. Published Projects | SRDR
    srdrplus.ahrq.gov/published_projects?page=32
    June 27, 2021 - radiofrequency ablation (RFA) and high ligation plus stripping, but RFA was associated with less periprocedural pain … patients treated with EVLA, those treated with foam sclerotherapy had significantly less periprocedural pain … higher rates of repeat intervention, and patients treated with RFA had significantly less periprocedural pain

16. Published Projects | SRDR
    srdrplus.ahrq.gov/published_projects?page=53
    March 03, 2021 - Narrative analysis was used for pain, quality of life (QoL), and functional outcomes due to inconsistently … Nor, on the whole, do pain, functioning, and QoL.

17. Published Projects | SRDR
    srdrplus.ahrq.gov/published_projects?page=10
    November 22, 2023 - Common adverse effects of PAP and MADs included oral or nasal dryness, irritation, and pain, among others … Common adverse effects of PAP and MADs included oral or nasal dryness, irritation, and pain, among others … Common adverse effects of PAP and MADs included oral or nasal dryness, irritation, and pain, among others

18. Published Projects | SRDR
    srdrplus.ahrq.gov/published_projects?page=44
    June 27, 2021 - reviewed to identify patient-reported outcomes (FI episodes, FI severity, quality of life, urgency, pain

19. Published Projects | SRDR
    srdrplus.ahrq.gov/published_projects?page=50
    June 23, 2021 - Results: Viscosupplementation trials generally report positive effects on pain and function scores compared

20. Published Projects | SRDR
    srdrplus.ahrq.gov/published_projects?page=43
    June 27, 2021 - outcomes and nearly all sleep parameters in the general adult population, older adults, and adults with pain