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81. App-F2-Surv-Report-3-Nonopioid-Pharmacol-Chronic-Pain (xls file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-f2-surv-report-3-nonopioid-pharmacol-chronic-pain.xlsx
    May 29, 2025 - Harms of tricyclic antidepressants versus placebo Author, Year Quality Pain Population Drug Class Drug … Harms of serotonin–norepinephrine reuptake inhibitor versus placebo Author, Year Quality Pain Population … Harms of pregabalin versus placebo Author, Year Quality Pain Population Drug Class Drug Assessment Time … Harms of pregabalin CR versus IR Author, Year Quality Pain Population Drug Class Drug Assessment Time … Harms of cannabis versus placebo Author, Year Quality Pain Population Drug Assessment Time (Wk) Time

82. App-F2-Surv-Report-2-Nonopioid-Pharmacol-Chronic-Pain (xls file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-f2-surv-report-2-nonopioid-pharmacol-chronic-pain.xlsx
    May 29, 2025 - Harms of tricyclic antidepressants versus placebo Author, Year Quality Pain Population Drug Class Drug … Harms of pregabalin versus placebo Author, Year Quality Pain Population Drug Class Drug Assessment Time … NR NR NR NR Tired 85 129 153 66 122 153 NR NR NR Horne, 2020 and Hewitt, 2020 Good Chronic pelvic pain … Harms of pregabalin CR versus IR Author, Year Quality Pain Population Drug Class Drug Assessment Time … Harms of cannabis versus placebo Author, Year Quality Pain Population Drug Assessment Time (Wk) Time

83. App-F1-Surv-Report-1-Nonopioid-Pharmacol-Chronic-Pain (xls file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-f1-surv-report-1-nonopioid-pharmacol-chronic-pain.xlsx
    May 29, 2025 - Pain severity for neuropathic pain Author, Year Quality Pain Population Drug Class 1 Drug Class 2 Drug … Pain response for neuropathic pain Author, Year Quality Pain Population Drug Class Drug Response Criteria … Function outcomes for neuropathic pain Author, Year Quality Pain Population Drug Class 1 Drug Class … Pain severity for low back pain Author, Year Quality Pain Population Drug Class 1 Drug Class 2 Drug … Pain response for low back pain Author, Year Quality Pain Population Drug Class Drug Response Criteria

84. App-F2-Surv-Report-1-Nonopioid-Pharmacol-Chronic-Pain (xls file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-f2-surv-report-1-nonopioid-pharmacol-chronic-pain.xlsx
    May 29, 2025 - Harms of tricyclic antidepressants versus placebo Author, Year Quality Pain Population Drug Class Drug … Harms of pregabalin versus placebo Author, Year Quality Pain Population Drug Class Drug Assessment Time … Harms of pregabalin CR versus IR Author, Year Quality Pain Population Drug Class Drug Assessment Time … Harms of cannabis versus placebo Author, Year Quality Pain Population Drug Assessment Time (Wk) Time … : n Application Site Pain: N N Randomized Application Site Pruritus: n Application Site Pruritus: N N

85. Systematic Review on Noninvasive Nonpharmacological Treatment for Chronic Pain: Surveillance Report 2 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/surveillance-report-2-noninvasive-nonpharma.pdf
    April 01, 2022 - conditions: low back pain (LBP); neck pain; knee, hip, or hand osteoarthritis (OA); fibromyalgia (FM … / or ((back or spine or spinal) adj2 pain).ti,ab. 2 exp Chronic Pain/ 3 Neck Pain/ or neck.ti,ab. … / or ((back or spine or spinal) adj2 pain).ti,ab. 2 exp Chronic Pain/ 3 Neck Pain/ or neck.ti,ab. … ) conditions: low back pain, neck pain, osteoarthritis pain, fibromyalgia, or tension headache … , nonradicular low back pain KQ1: Low back pain • Patients with radiculopathy • Low back pain

86. CER 220 Evidence Summary: Comparative Effectiveness of Analgesics To Reduce Acute Pain in the Prehospital Setting (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-220-analgesics-acute-pain-summary.pdf
    September 01, 2019 - have insufficient prehospital pain relief. … Patient with moderate to severe, acute pain Health Outcomes Pain score Presence of pain Time … relief may reduce pain more and may reduce pain more quickly. … Low-dose ketamine improves pain relief in patients receiving intravenous opioids for acute pain in … Change in pain score after administration of analgesics for lower extremity fracture pain during hospitalization

87. Living Systematic Review on Plant-Based Treatment for Chronic Pain (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/plant-based-treatments-revised-protocol.pdf
    March 29, 2023 - of chronic pain? … are included in this category), musculoskeletal pain (including low-back pain), visceral pain, fibromyalgia … March 29, 2023 Table 1: Population Excluded subacute pain Added subacute pain Subacute pain, … exp arthralgia/ or exp back pain/ or exp headache/ or exp musculoskeletal pain/ or neck pain/ or exp … neuralgia/ or exp nociceptive pain/ or pain, intractable/ or fibromyalgia/ or myalgia/ 3 Pain/

88. App-D-Opioid-Chronic-Pain-Surveill-Report-1 (xls file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-d-opioid-chronic-pain-surveill-report-1.xlsx
    September 30, 2015 - Pain > 3 months, currently prescribed opioids; excluded cancer and end-of-life treatment A. … clinic Netherlands Pain condition: Nonspecific chronic low back pain Age: 18 to 75 Pain severity: NRS … and mental health conditions; medication classes; heath care visits; NRS pain scores A vs. … Extreme/severe pain interference: A vs. C: aOR 2.91 (95% CI 1.95 to 4.32); B vs. … C: aOR 0.86 (95% CI 0.58 to 1.28) Moderate pain interference: A vs.

89. App-D-Opioid-Chronic-Pain-Surveillance-Report-3 (xls file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-d-opioid-chronic-pain-surveillance-report-3.xlsx
    September 30, 2015 - : NRS pain scale ≥ 4 Exclusion: Neuropathic pain A. … condition: Chronic low back pain Age: ≥18 years Pain severity: mean ≥5 on NRS pain scale Exclusions: … Pain condition: Moderate to severe osteoarthritis pain of the hip or knee Age: NR Pain severity: WOMAC … clinic Netherlands Pain condition: Nonspecific chronic low back pain Age: 18 to 75 Pain severity: NRS … diagnoses: Back pain: 82% vs. 76% vs. 74% Neck pain: 19% vs. 33% vs. 31% Other joint pain: 47% vs. 44%

90. App-D-Opioid-Chronic-Pain-Surveillance-Report-2 (xls file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-d-opioid-chronic-pain-surveillance-report-2.xlsx
    September 30, 2015 - Pain > 3 months, currently prescribed opioids; excluded cancer and end-of-life treatment A. … clinic Netherlands Pain condition: Nonspecific chronic low back pain Age: 18 to 75 Pain severity: NRS … and mental health conditions; medication classes; heath care visits; NRS pain scores A vs. … Extreme/severe pain interference: A vs. C: aOR 2.91 (95% CI 1.95 to 4.32); B vs. … C: aOR 0.86 (95% CI 0.58 to 1.28) Moderate pain interference: A vs.

91. Executive Summary: Pain Management Interventions for Hip Fracture (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/cer30_hip-fracture-pain-executive-summary_20110517.pdf
    May 01, 2011 - KQ 1: Acute pain management. All three trials reported acute pain. … KQ 1: Acute pain management. The average baseline VAS pain score was 4.7. … Pain was measured using the VAS; the mean baseline measure was 8.4 to 8.8. KQ 1: Acute pain. … Pain was measured using the 10cm VAS; the mean baseline measure was 7.9cm. KQ 1: Acute pain. … KQ 1: Acute pain management.

92. Nonopioid Pharmacologic Treatments for Chronic Pain: Appendix E (xls file)
    effectivehealthcare.ahrq.gov/sites/default/files/nonopioid-chronic-pain-ape_0.xlsx
    August 08, 2017 - duration, mo: 52 Baseline pain intensity, MNSI: 5 24h average pain (0-10): 6 24h worst pain severity … duration, mo: 46 Baseline pain intensity: 24h average pain severity (0-10): 6 24h worst pain severity … duration, mo: 52 Baseline pain intensity, 24-h Average pain score (Brief Pain Inventory): 6 Baseline … duration, mo: 93 Baseline pain intensity, VAS (0-100): 68 McGill pain index: 28 McGill present pain … duration, mo: 89 Baseline pain intensity, BPI average pain (0 to 10): 6 Weekly 24-hour average pain

93. Topic 0552 Low Back Pain NSD FINAL SJ (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0651-131114.pdf
    June 20, 2013 - , non-radicular low back pain, or spinal stenosis? … , non-radicular low back pain, or spinal stenosis? … , radicular low back pain, or spinal stenosis? … , radicular low back pain, or spinal stenosis? … of flares of low back pain in patients with chronic low back pain?

94. CER 220: Disposition of Comments Report for Comparative Effectiveness of Analgesics To Reduce Acute Pain in the Prehospital Setting (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-220-disposition-comments-analgesics-prehospital-setting.pdf
    September 03, 2019 - associated with acute pain”. … pain? … superimposed acute pain. … For the subgroup of traumatic pain, for the comparison of opioid versus APAP, change in pain scores … medications to treat acute pain.

95. Methods Research Report: Testing a Machine Learning Tool for Facilitating Living Systematic Reviews of Chronic Pain Treatments (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-report-testing-machine-learning-tool-chronic-pain.pdf
    November 01, 2020 - or "musculoskeletal pain" or osteoarthritis or "low back pain" or "neck pain" or "inflammatory pain … pain/ or neck pain/ or exp neuralgia/ or exp nociceptive pain/ or pain, intractable/ or fibromyalgia … or "musculoskeletal pain" or osteoarthritis or "low back pain" or "neck pain" or "inflammatory pain … or "musculoskeletal pain" or osteoarthritis or "low back pain" or "neck pain" or "inflammatory pain … pain.

96. Executive summary_Comparative Effectiveness Review No. 250_Living Systematic Review on Cannabis and Other Plant-Based Treatments for Chronic Pain: 2025 Update (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-2025-surv-rep-update-executive-sum.pdf
    January 01, 2025 - ; 3-4 drops for for moderate pain; 5-6 drops for severe pain Risk of Bias 25% high, 63% moderate … pain NPP Peripheral NPP Peripheral neuropathic back pain Baseline Pain Score, Mean (Range)c … weeks to <6 months) Product, THC to CBD Ratio Pain Responsea Effect Size (N Studies) [SOE] Pain … in pain). … Cannabis combined with oxycodone for pain relief in fibromyalgia pain: a randomized clinical self-titration

97. App-E-Opioid-Chronic-Pain-Surveillance-Report-2 (xls file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-e-opioid-chronic-pain-surveillance-report-2.xlsx
    January 01, 2021 - Table E-1. RCT QA Table E-1. RCT quality assessment Author, Year Randomization Adequate? Allocation Concealment Adequate? Groups Similar at Baseline? Outcome Assessors Masked? Care Provider Masked? Patient Masked? Intention-To-Treat (ITT) Analysis Acceptable Levels of Overall Attrition and Between-Group Differences…

98. App-E-Opioid-Chronic-Pain-Surveillance-Report-3 (xls file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-e-opioid-chronic-pain-surveillance-report-3.xlsx
    January 01, 2021 - Table E-1. RCT QA Table E-1. RCT quality assessment Author, Year Randomization Adequate? Allocation Concealment Adequate? Groups Similar at Baseline? Outcome Assessors Masked? Care Provider Masked? Patient Masked? Intention-To-Treat (ITT) Analysis Acceptable Levels of Overall Attrition and Between-Group Differences…

99. App-E-Opioid-Chronic-Pain-Surveill-Report-1 (xls file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-e-opioid-chronic-pain-surveill-report-1.xlsx
    January 01, 2021 - Table E-1. RCT QA Table E-1. RCT quality assessment Author, Year Randomization Adequate? Allocation Concealment Adequate? Groups Similar at Baseline? Outcome Assessors Masked? Care Provider Masked? Patient Masked? Intention-to-Treat (ITT) Analysis Acceptable Levels of Overall Attrition and Between-Group Differences…

100. Disposition of Comments: CER 227 Noninvasive Nonpharmacological Treatment for Chronic Pain (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/cer-227-noninvasive-nonpharm-chronic-pain-comments.pdf
     April 16, 2020 - We request that AHRQ clarify if a numeric pain scale is the only pain measure. … Pain score among others. … Effects of anger suppression on pain severity and pain behaviors among chronic pain patients: evaluation … Pain, 151(2), 280- 295. … PAIN, 158, 2354-2363.