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  1. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/antidepressants-update_executive.pdf
    December 01, 2011 - Pain Two fair-quality trials that required baseline pain for inclusion produced conflicting evidence … Pain One fair-quality systematic review showed that improvement in pain scores was similar for duloxetine … for the superiority of duloxetine or paroxetine compared with placebo for treatment of accompanying pain … Comparative effectiveness for Insufficient No evidence depression Comparative efficacy for pain Moderate … Comparative effectiveness for Insufficient No evidence pain Psychomotor change Comparative efficacy
  2. effectivehealthcare.ahrq.gov/sites/default/files/01_arthritis_potential_high_impact_2012-12-10.pdf
    January 01, 2012 - The investigators reported that patients treated with MSC therapy had improvements in patient pain … Fifty-foot walk pain improved 26% and 17% from baseline at 6 and 12 months, respectively. … Increases in swelling (p=0.03) and pain reaction (p=0.0005) were observed in patients treated with … The mean VAS to measure pain severity at baseline was 8.2 (range 7–10); it was 3.2 (range 1–4) and … Pain Physician 2008 May-Jun;11(3):343-53. PMID: 18523506 4. Wei N, Beard S, Delauter S, et al.
  3. effectivehealthcare.ahrq.gov/sites/default/files/related_files/migraine_protocol-appendix_20111103.pdf
    November 03, 2011 - With BioSTAR® Bioabsorbable Septal Repair Implant NCT01161017 Mechanism-based Choice of Therapy for Pain … : Can Successful Prevention of Migraine be Coupled to a Psychophysical Pain Modulation Profile? … Topiramate for Preventing Migraine Headaches NCT00904527 Interest of Relaxation From Patients With Pain … Headache NCT00551980 The Efficacy of a Cognitive and Physical Intervention to Reduce Head and Muscle Pain
  4. effectivehealthcare.ahrq.gov/sites/default/files/pdf/rotator-cuff-tears-future_research.pdf
    February 01, 2013 - The outcomes included health-related quality of life, return to work, pain, shoulder function, rotator … Examined outcomes included health-related quality of life, return to work, pain, shoulder function, … J Shoulder Elbow Surg, 2009: www.ncbi.nlm.nih.gov/pubmed/19535272 Postoperative pain NCT01204606 … Oxycodone IR for acute postoperative pain after elective arthroscopic shoulder surgery (repairs of … The outcomes examined were health-related quality of life, return to work, pain, shoulder function,
  5. effectivehealthcare.ahrq.gov/sites/default/files/related_files/assessing-applicability-quiz.ppt
    May 29, 2025 - point (e.g., death, nonfatal myocardial infarction, ventricular fibrillation, stroke, or stable anginal pain … point (e.g., death, nonfatal myocardial infarction, ventricular fibrillation, stroke, or stable anginal pain
  6. effectivehealthcare.ahrq.gov/sites/default/files/assessing-applicability-quiz.ppt
    May 29, 2025 - point (e.g., death, nonfatal myocardial infarction, ventricular fibrillation, stroke, or stable anginal pain … point (e.g., death, nonfatal myocardial infarction, ventricular fibrillation, stroke, or stable anginal pain
  7. effectivehealthcare.ahrq.gov/sites/default/files/pdf/cancer-end-of-life-quality-meaures_research.pdf
    April 01, 2010 - The adequate treatment of pain at the end-of-life is a cornerstone of end-of-life care,12 and opiates … are a central to these pain treatment regimens. … Pain and its treatment in outpatients with metastatic cancer. … Management of cancer symptoms: pain, depression and fatigue. 2002. Report No.: 02-E032. 14. … J Pain Symptom Manage 2007;33(5):521-526. 38. Miaskowski C, Dodd MJ, West C, et al.
  8. effectivehealthcare.ahrq.gov/sites/default/files/cer-238-cervical-ripening-appendix-e-1.xlsx
    January 01, 2009 - Patient communicated with RN every 4 hours to capture pain and satisfaction scores. … heart was normal, the woman was sent home. _ The patient was advised to return if she had abdominal pain … -Instructed to return if they experienced uterine contractions, pain, vaginal bleeding, or rupture of … -Instructed to return if they experienced uterine contractions, pain, vaginal bleeding, or rupture of … contractions occur every 5 minutes or less, they experience rupture of membranes, severe abdominal pain
  9. effectivehealthcare.ahrq.gov/sites/default/files/related_files/tethered-spinal-cord-protocol.pdf
    July 19, 2023 - Patients often present with pain, motor or sensory dysfunction, or bladder and bowel functional disturbances … (TEP) resulted in adding a further stratification by symptom type for KQ3a to distinguish between pain … diagnosis) KQ2-4: Patient health and other patient effects such as leg weakness, leg numbness, leg pain … , other pain, gait, walking difficulty, bowel incontinence, bladder incontinence, scoliosis, disability … for symptomatic patients) outcomes: neurological status, ambulation, standardized symptoms scores, pain
  10. effectivehealthcare.ahrq.gov/sites/default/files/related_files/pressure-ulcer-treatment_executive.pdf
    May 01, 2013 - including but not limited to: complete wound healing, healing time, reduced wound surface area, pain … • Bleeding • Infection • Complete wound healing • Wound surface area • Healing time • Pain … Other outcomes included pain and avoidance of serious complications of infection. … For harms of treatment, we evaluated pain, dermatologic complications, bleeding, infection, and other … Other outcomes, including pain, were reported sporadically.
  11. effectivehealthcare.ahrq.gov/sites/default/files/cer-245-breast-reconstruction-after-mastectomy-evidence-summary-updated-1.pdf
    October 01, 2021 - surgical outcome, or risks of reconstructive failure, infections that are not explicitly implant-related, pain … whether ADM use impacts physical well-being, psychosocial well-being, satisfaction with breasts, pain … nd Pain ↑↓ ? nd ↑↓ ↑↓ ? Analgesic use ? nd nd ? ? nd Necrosis ? ? nd ?
  12. effectivehealthcare.ahrq.gov/sites/default/files/related_files/genitourinary-symptoms-protocol_0.pdf
    July 10, 2023 - vaginitis, vaginal dryness, vaginal / vulvar irritation, vaginal soreness, vaginal lubrication, vaginal pain … : vaginal burning, vaginal bleeding, vaginal discharge, vaginal scarring, vaginal stenosis; pelvic pain … Systemic adverse events: chronic pain, stroke; VTE (DVT or PE); death; hot flashes; headache; breast … pain; cramps; bloating; nausea; vomiting Timing All KQ Intervention: any Outcomes: any … / or sexual dysfunction, physiological/ or (dyspareunia or sexual dysfunction or pelvic pain).ti,ab.
  13. effectivehealthcare.ahrq.gov/sites/default/files/pdf/gout_research-protocol-2014.pdf
    January 01, 2014 - arthritis characterized by acute intermittent episodes of synovitis presenting with joint swelling and pain … What are the adverse effects associated with each diagnostic test (including pain, infection at the … pain, joint swelling and tenderness, ! … pain, infection, radiation exposure and ! … swelling, and any adverse events (including adverse patient experiences such as pain
  14. effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/pdf/epc-year-in-review-2023.pdf
    January 01, 2023 - Projects 2 Manuscripts 11 Presentations Goal 4: Improving Evidence Quality Research Gap Summaries Pain … Cannabis-Based Products for Chronic Pain (published in Annals of Internal Medicine in August 2022) has … Living Systematic Review on Cannabis and Other Plant-Based Treatments for Chronic Pain: 2023 Update … Systematic Review of Peripheral Nerve Blocks for Postoperative Pain Management 41. … AHRQ Evidence-based Practice Center (EPC) Program Research Gaps Summary: Pain Management 3.
  15. effectivehealthcare.ahrq.gov/sites/default/files/pdf/osteoporosis-vibration-therapy_technical-brief.pdf
    January 01, 2020 - fractures, in particular, are associated with an increased risk of death.1 Fractures can also cause pain … of whole-body vibration exercise on lumbar bone mineral density, bone turnover, and chronic back pain … Low back pain in drivers exposed to whole body vibration: analysis of a dose- response pattern. … subjects had taken medication such as nonsteroid anti-inflammatory drugs to relieve chronic back pain … Yes – some patients reported itching after vibration session; one patient reported localized pain
  16. effectivehealthcare.ahrq.gov/sites/default/files/coronary-artery-disease-testing_disposition-comments.pdf
    March 29, 2016 - than any luminal irregularities is used for CT is correct when trying to understand cause of chest pain … The emergency department sees patients with a variety of causes of chest pain, many of which can mimic … A negative stress test would provoke further evaluation for other etiologies of the chest pain. … Coronary CT angiography versus standard evaluation in acute chest pain. … Triage of Patients Presenting with Chest Pain to the Emergency Department: Implementation of Coronary
  17. effectivehealthcare.ahrq.gov/sites/default/files/pdf/chronic-cough_research-protocol.pdf
    October 22, 2012 - (57%), feeling self-conscious (55%), insomnia (45%), changes in life-style (45%), musculoskeletal pain … but not limited to:  Sleep disturbance  Allergic reaction  Drowsiness  Headache  Chest pain … on patient and provider decisionmaking Patient outcome efficacy • Acceptability • HRQOL • Chest pain … provider decisionmaking) o Patient outcome efficacy (e.g., acceptability, quality of life, chest pain … Oral Approved May cause upper respiratory infection, fever, headache, sore throat, cough, stomach pain
  18. Santa_ECCS2012 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/santa_eccs2012.pdf
    February 01, 2013 -   • Each rating  was based on a Cochrane  review. o Example: Lower back pain interventions …  Survey results from  patients with back pain  Strength  of the evidence Source: Eisenberg Center … smear o Bone density o Heart imaging o Colon cancer • Diagnosis of common symptoms o Low back pain
  19. effectivehealthcare.ahrq.gov/sites/default/files/pdf/insomnia_consumer.pdf
    August 01, 2017 - example, Parkinson’s disease or Alzheimer’s disease), fibromyalgia (a disorder that causes muscle pain … ), or rheumatoid arthritis (a disorder that causes pain and swelling in the joints) … How often you drink alcohol � If you smoke � If you exercise regularly � If you have any chronic pain
  20. effectivehealthcare.ahrq.gov/sites/default/files/coronary-artery-disease-testing_executive.pdf
    March 01, 2011 - with an estimated 1.5 percent of the population presenting to health care providers with chest pain … blood either at rest or during exertion.5,6 The most common symptom of obstructive CAD is chest pain … In addition to physical examination and patient history for people presenting with chest pain to the … Chest pain in general practice: incidence, comorbidity and mortality. … Coronary CT angiography versus standard evaluation in acute chest pain.

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