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effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/pdf/epc-pain-management-grand-rounds-slides.pptx
March 01, 2022 - Nonpharmacologic Treatments for Chronic Pain
9
BACKGROUND
Chronic pain:
Pain lasting ≥ 3 months or … In adults with chronic pain, what are the harms of cannabinoids for treatment of chronic pain? … of chronic pain? … of chronic pain? … to chronic pain).
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/draft-living-review-plant-chronic-pain-e-evidence-tables.xlsx
March 25, 2024 - on movement; morning stiffness; SF-MPQ total intensity of pain; SF-MPQ, pain at present; McGill Pain … outcome of SF-36 bodily pain domain. … reduction, Neuropathic Pain Symptom Index, pain relief (patient diary); no differences between groups … , muscle pain, blurred vision
Table E-4. … NA not applicable
NPP neuropathic pain
NPS Neuropathic Pain Scale
NR not reported
NRS numeric
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/pbt-lsr-draft-ets-obs.xlsx
March 15, 2022 - Cannabis cohort studies
PMID Author, Year Study Design Setting Pain Population Pain Condition Age Measure … Age, Years Female % Race, White % Race, Black % Race, Hispanic/Latino % Race, Asian % Race, Other % Pain … B
Pain Interference (Adjusted mean [SE]; BPI pain interference, 0-10 scale)
5.2 (0.19) vs. 5.4 (0.04) … , gender, stage of chronification, severity of chronic pain, pain phenotype, pain duration, mean 24-hour … pain intensity, current and past pain medications, comorbidities, comedications, and reasons for switching
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cannabis-annual-update2-table-e5.xlsx
March 13, 2023 - Cannabis cohort studies
PMID Author, Year Study Design Setting Pain Population Pain Condition Age Measure … Age, Years Female % Race, White % Race, Black % Race, Hispanic/Latino % Race, Asian % Race, Other % Pain … B
Pain Interference (Adjusted mean [SE]; BPI pain interference, 0-10 scale)
5.2 (0.19) vs. 5.4 (0.04) … , gender, stage of chronification, severity of chronic pain, pain phenotype, pain duration, mean 24-hour … pain intensity, current and past pain medications, comorbidities, comedications, and reasons for switching
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cannabis-2022-update-surv-rep-1-app-F-5.xlsx
January 01, 2022 - Cannabis cohort studies
PMID Author, Year Study Design Setting Pain Population Pain Condition Age Measure … Age, Years Female % Race, White % Race, Black % Race, Hispanic/Latino % Race, Asian % Race, Other % Pain … B
Pain Interference (Adjusted mean [SE]; BPI pain interference, 0-10 scale)
5.2 (0.19) vs. 5.4 (0.04) … , gender, stage of chronification, severity of chronic pain, pain phenotype, pain duration, mean 24-hour … pain intensity, current and past pain medications, comorbidities, comedications, and reasons for switching
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cannabis-2022-surv-rep-3-table-F5.xlsx
January 01, 2022 - Cannabis cohort studies
PMID Author, Year Study Design Setting Pain Population Pain Condition Age Measure … Age, Years Female % Race, White % Race, Black % Race, Hispanic/Latino % Race, Asian % Race, Other % Pain … B
Pain Interference (Adjusted mean [SE]; BPI pain interference, 0-10 scale)
5.2 (0.19) vs. 5.4 (0.04) … , gender, stage of chronification, severity of chronic pain, pain phenotype, pain duration, mean 24-hour … pain intensity, current and past pain medications, comorbidities, comedications, and reasons for switching
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effectivehealthcare.ahrq.gov/sites/default/files/hip-fracture-pain_surveillance.pdf
July 08, 2015 - * or discomfort* or ache* or aching or so re* or suffer*) adj3
(assess* or relief or reliev* or reduc … /rt, th, us, rh, dh, su, pc, dt (137447)
8 pain postoperative/pc, th (10986)
9 Pain Measurement/ … Outcomes: Primary outcomes – acute pain, chronic pain; secondary outcomes – mortality,
functional status … All three trials reported acute pain. … Multimodal Pain Management:
Two cohort studies (n = 226)
evaluated multimodal pain
management versus
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effectivehealthcare.ahrq.gov/get-involved/nominated-topics/chronic-pelvic-pain-syndrome-men
May 18, 2021 - Chronic Orchialgia, Orchidynia, Testalgia, Scrotal Contents Pain, Chronic Scrotal Pain or Chronic Testicular … Pain. … ), sexual pain syndrome, myofascial pain syndromes, prostate pain syndrome, scrotal pain syndrome, urethral … pain syndrome, vaginal and vulvar pain syndromes and CPPS and prolapse/incontinence mesh.(3) It reviews … Fall M, Baranowski AP, Elneil S et al: EAU guidelines on chronic pelvic pain.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-d-opioid-chronic-pain-surveill-report-1.xlsx
September 30, 2015 - Pain > 3 months, currently prescribed opioids; excluded cancer and end-of-life treatment A. … clinic
Netherlands Pain condition: Nonspecific chronic low back pain
Age: 18 to 75
Pain severity: NRS … and mental health conditions; medication classes; heath care visits; NRS pain scores A vs. … Extreme/severe pain interference: A vs. C: aOR 2.91 (95% CI 1.95 to 4.32); B vs. … C: aOR 0.86 (95% CI 0.58 to 1.28)
Moderate pain interference: A vs.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-d-opioid-chronic-pain-surveillance-report-2.xlsx
September 30, 2015 - Pain > 3 months, currently prescribed opioids; excluded cancer and end-of-life treatment A. … clinic
Netherlands Pain condition: Nonspecific chronic low back pain
Age: 18 to 75
Pain severity: NRS … and mental health conditions; medication classes; heath care visits; NRS pain scores A vs. … Extreme/severe pain interference: A vs. C: aOR 2.91 (95% CI 1.95 to 4.32); B vs. … C: aOR 0.86 (95% CI 0.58 to 1.28)
Moderate pain interference: A vs.
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effectivehealthcare.ahrq.gov/health-topics/bone-diseases
November 15, 2011 - Technical Brief: Use and Safety of Positional MRI in the Management of Patients with Musculoskeletal Pain … Breast Cancer
Research Protocol
Archived
December 17, 2013
Early Imaging for Back Pain
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-table-e5-2022-update_0.xlsx
January 01, 2022 - Cannabis cohort studies
PMID Author, Year Study Design Setting Pain Population Pain Condition Age Measure … Age, Years Female % Race, White % Race, Black % Race, Hispanic/Latino % Race, Asian % Race, Other % Pain … B
Pain Interference (Adjusted mean [SE]; BPI pain interference, 0-10 scale)
5.2 (0.19) vs. 5.4 (0.04) … , gender, stage of chronification, severity of chronic pain, pain phenotype, pain duration, mean 24-hour … pain intensity, current and past pain medications, comorbidities, comedications, and reasons for switching
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/scope-communicating-evolving-evidence-white-paper.pdf
July 01, 2023 - Chronic pain is difficult to treat successfully. … ; and use of cannabis for spasticity without
pain … (though studies of patients with spasticity without chronic pain or
with unclear chronic pain are excluded … The SOE tables display results for different cannabis product categories
8
for pain response, pain … weeks to <6 months)
Product, THC to CBD Ratio
Pain Response
Effect Size (N Studies)
[SOE]
Pain
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/plant-based-chronic-pain-review-q3-tables-g.xlsx
June 15, 2021 - Table G-1. ROB RCTs
Table G-1. Risk of bias of cannabis RCTs
Author, Year Randomization Adequate? Allocation Concealment Adequate? Groups Similar at Baseline? Patient Masked? Care Provider Masked? Outcome Assessors Masked? Intention-to-Treat Analysis? Rate of Overall Attrition Within Acceptable Levels? Rate of Diffe…
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-e-opioid-chronic-pain-surveillance-report-3.xlsx
January 01, 2021 - Table E-1. RCT QA
Table E-1. RCT quality assessment
Author, Year Randomization Adequate? Allocation Concealment Adequate? Groups Similar at Baseline? Outcome Assessors Masked? Care Provider Masked? Patient Masked? Intention-To-Treat (ITT) Analysis Acceptable Levels of Overall Attrition and Between-Group Differences…
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-e-opioid-chronic-pain-surveill-report-1.xlsx
January 01, 2021 - Table E-1. RCT QA
Table E-1. RCT quality assessment
Author,
Year Randomization Adequate? Allocation Concealment Adequate? Groups Similar at Baseline? Outcome Assessors Masked? Care Provider Masked? Patient Masked? Intention-to-Treat (ITT) Analysis Acceptable Levels of Overall Attrition and Between-Group Differences…
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-e-opioid-chronic-pain-surveillance-report-2.xlsx
January 01, 2021 - Table E-1. RCT QA
Table E-1. RCT quality assessment
Author,
Year Randomization Adequate? Allocation Concealment Adequate? Groups Similar at Baseline? Outcome Assessors Masked? Care Provider Masked? Patient Masked? Intention-To-Treat (ITT) Analysis Acceptable Levels of Overall Attrition and Between-Group Differences…
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/pain-chronic_research-protocol.pdf
July 28, 2010 - back pain, upper
extremity pain disability, peripheral neuropathies, et cetera. … The goal of chronic pain treatment has evolved from eliminating pain to
managing pain to an extent that … Patients with acute pain (e.g. pain less than 3 months and post-surgical pain)
3. … Journal of Pain 2006
Nov; 7(11):779-93.
3. American Pain Society. … American Pain Society. Pain Advocacy.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/pain-chronic_disposition-comments.pdf
September 01, 2011 - Multidisciplinary
Pain Programs for Chronic Noncancer Pain. Technical Brief No. 8. … Chronic Non-cancer Pain. … of chronic pain, which would then
allow chronic pain to be further differentiated from acute pain. … pain diagnosis. … presentations low back pain and other pain disorder/ versus low back
pain could be mentioned.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoarthritis-pain-2006_executive.pdf
January 01, 2006 - It is the most common form of
arthritis and is associated with pain,
substantial disability, and reduced … NSAIDs
decrease pain, inflammation, and fever by blocking
cyclo-oxygenase (COX) enzymes. … COX-2 is found in joint and muscle, and
mediates effects on pain and inflammation. … By blocking
COX-2, NSAIDs reduce pain compared to placebo in
patients with arthritis, low back pain, … benefit for
pain relief, but this did not appear to be a
preplanned analysis