-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/topic-brief1-care-coordination.pdf
April 01, 2021 - and none included studies of patients with
pain or reported key pain-related outcomes (e.g., pain intensity … conditions, pain duration, pain severity, comorbidities, use of opioids or other pain treatments)? … or
reported key pain-related outcomes (e.g., pain intensity, pain-related function, opioid
utilization … conditions, but
should evaluate outcomes relevant for patients with pain such as pain, pain-related … /
8 exp arthralgia/ or exp back pain/ or exp headache/ or exp musculoskeletal pain/ or neck pain
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/lumbar-fusion-draft-report-appendix-d.xlsx
January 01, 2019 - - PLF: 66
Lumbar Pain - PLF + TLIF: 57
Radicular Pain - PLF: 48
Radicular Pain - PLF + TLIIF: 53 … Severe Back Pain (Pedicle Screw and Posterior Fusion): 1
Postoperative Severe Back Pain (No fusion … facet origin
Concomitant diagnoses:
-Disc degeneration: 15%
-Ligament calcification: 9%
-FBSS: 21%
-Radiating … Pain: 31%
NR Radiating pain: 31% A vs. … Changes in back pain NRS, leg pain NRS, and RDQ stratified by opioid vs non-opioid treatment at baseline
-
effectivehealthcare.ahrq.gov/sites/default/files/hip-fracture-pain_surveillance.pdf
July 08, 2015 - * or discomfort* or ache* or aching or so re* or suffer*) adj3
(assess* or relief or reliev* or reduc … /rt, th, us, rh, dh, su, pc, dt (137447)
8 pain postoperative/pc, th (10986)
9 Pain Measurement/ … Outcomes: Primary outcomes – acute pain, chronic pain; secondary outcomes – mortality,
functional status … All three trials reported acute pain. … Multimodal Pain Management:
Two cohort studies (n = 226)
evaluated multimodal pain
management versus
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-2025-surv-rep-update-table-e5.xlsx
January 01, 2025 - Cannabis cohort studies
PMID Author, Year Study Design Setting Pain Population Pain Condition Age Measure … B
Pain Interference (Adjusted mean [SE]; BPI pain interference, 0-10 scale)
5.2 (0.19) vs. 5.4 (0.04) … Joint pain was associated with a -0.05-point reduction in pain vs. muscle pain, cannabis products with … and disorders related to chronic pain (e.g., arthritis, back-related pain, disc-related
pain, complicated … , gender, stage of chronification, severity of chronic pain, pain phenotype, pain duration, mean 24-hour
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/topic-brief2-opioid-withdrawal.pdf
April 01, 2021 - Todd Graham Pain Management Study, to inform a report to
Congress on acute and chronic pain management … conditions, pain duration, pain severity, comorbidities, use of opioids
or other pain treatments)? … pain
rehabilitation program. … Prevalence of Chronic Pain and High-Impact Chronic Pain Among Adults
— United States, 2016. … /
3 exp arthralgia/ or exp back pain/ or exp headache/ or exp musculoskeletal pain/ or neck pain
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/topic-brief2-opioid-withdrawal.pdf
April 01, 2021 - Todd Graham Pain Management Study, to inform a report to
Congress on acute and chronic pain management … conditions, pain duration, pain severity, comorbidities, use of opioids
or other pain treatments)? … pain
rehabilitation program. … Prevalence of Chronic Pain and High-Impact Chronic Pain Among Adults
— United States, 2016. … /
3 exp arthralgia/ or exp back pain/ or exp headache/ or exp musculoskeletal pain/ or neck pain
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/scope-communicating-evolving-evidence-white-paper_0.pdf
June 01, 2025 - Chronic pain is difficult to treat successfully. … ; and use of cannabis for spasticity without
pain … (though studies of patients with spasticity without chronic pain or
with unclear chronic pain are excluded … The SOE tables display results for different cannabis product categories
8
for pain response, pain … weeks to <6 months)
Product, THC to CBD Ratio
Pain Response
Effect Size (N Studies)
[SOE]
Pain
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/acute-pain-ems-protocol-amendment.pdf
January 28, 2019 - acute pain.2 However, as many as 43%
of individuals have insufficient prehospital pain relief.3 Reasons … o Studies that target mild pain or non-zero pain to administer analgesics will
be excluded. … o KQ1a, 2a, 3a, 4a: Age, source of pain, severity of pain, medical condition
(including chronic pain … Health outcomes
Pain score
Presence of pain
Time to analgesic effect
Memory of pain
(KQ … and non-
traumatic pain.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-265-radiation-bone-disease-summary.pdf
August 01, 2023 - Overall pain response is used to reflect pain improvement. … Studies
defined pain response based on achieving a threshold for pain reduction; many studies
also … weeks and 26
weeks
Small
++
No difference
+
36 weeks Moderate
+ No evidence
Pain, VAS Pain … Use of
dexamethasone with EBRT may improve pain and quality of life and reduce pain flare
and acute … Studies used various definitions
of pain response.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/pelvic-pain-therapies-future_research.pdf
January 01, 2015 - or dyspareunia (pain with intercourse), dyschezia (pain
with bowel movement), or dysuria (pain with … perception
Iatrogenic Pain
Iatrogenic pain (pain resulting from a procedure or complication of a … pain, pelvic and abdominal visceral pain) in CPP? … chronic pelvic pain. … chronic pelvic pain.
-
effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/pdf/epc-pain-management-grand-rounds-slides.pptx
March 01, 2022 - Nonpharmacologic Treatments for Chronic Pain
9
BACKGROUND
Chronic pain:
Pain lasting ≥ 3 months or … In adults with chronic pain, what are the harms of cannabinoids for treatment of chronic pain? … of chronic pain? … of chronic pain? … to chronic pain).
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cannabis-app-f5-table-surveillance-report-2_0_0.xlsx
May 29, 2025 - Cannabis cohort studies
PMID Author, Year Study Design Setting Pain Population Pain Condition Age Measure … Age, Years Female % Race, White % Race, Black % Race, Hispanic/Latino % Race, Asian % Race, Other % Pain … Duration Measure
(Mean, Median) Pain Duration, Months Psychiatric Comorbidity % N Interventions Dose … Treatment Duration (Weeks) Assessment Time Category Baseline Pain Variables Accounted for in Analyses … B
Pain Interference (Adjusted mean [SE]; BPI pain interference, 0-10 scale)
5.2 (0.19) vs. 5.4 (0.04)
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/Appendix-E-Table-E5_0.xlsx
May 29, 2025 - Cannabis cohort studies
PMID Author, Year Study Design Setting Pain Population Pain Condition Age Measure … Age, years Female % Race, White % Race, Black % Race, Hispanic/Latino % Race, Asian % Race, other % Pain … Duration Measure
(Mean, Median) Pain Duration, Months Psychiatric Comorbidity % N Interventions Dose … Treatment Duration (Weeks) Assessment Time Category Baseline Pain Variables Accounted for in Analyses … B
Pain Interference (Adjusted mean [SE]; BPI pain interference, 0-10 scale)
5.2 (0.19) vs. 5.4 (0.04)
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cannabis-2022-update-surv-rep-1-app-F-5.xlsx
January 01, 2022 - Cannabis cohort studies
PMID Author, Year Study Design Setting Pain Population Pain Condition Age Measure … Age, Years Female % Race, White % Race, Black % Race, Hispanic/Latino % Race, Asian % Race, Other % Pain … B
Pain Interference (Adjusted mean [SE]; BPI pain interference, 0-10 scale)
5.2 (0.19) vs. 5.4 (0.04) … , gender, stage of chronification, severity of chronic pain, pain phenotype, pain duration, mean 24-hour … pain intensity, current and past pain medications, comorbidities, comedications, and reasons for switching
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cannabis-2022-surv-rep-3-table-F5.xlsx
January 01, 2022 - Cannabis cohort studies
PMID Author, Year Study Design Setting Pain Population Pain Condition Age Measure … Age, Years Female % Race, White % Race, Black % Race, Hispanic/Latino % Race, Asian % Race, Other % Pain … B
Pain Interference (Adjusted mean [SE]; BPI pain interference, 0-10 scale)
5.2 (0.19) vs. 5.4 (0.04) … , gender, stage of chronification, severity of chronic pain, pain phenotype, pain duration, mean 24-hour … pain intensity, current and past pain medications, comorbidities, comedications, and reasons for switching
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/fibromyalgia_research-protocol.pdf
April 03, 2014 - , abnormal pain
processing/heightened pain sensitivity, chronic fatigue, sleep disorders, and emotional … tachycardia, constipation, etc.)
§ Adverse effects from non-pharmaceutical treatments (such as muscle aches … , minor
injuries or falls during or after exercise; soreness or aches from passive physical
treatments … Pain assessment: global use of the Brief Pain Inventory. … The McGill Pain Questionnaire: major properties and scoring methods. Pain.
1975 Sep;1(3):277-99.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-2024-surv-rep-update-table-e5.xlsx
January 01, 2024 - Cannabis cohort studies
PMID Author, Year Study Design Setting Pain Population Pain Condition Age Measure … B
Pain Interference (Adjusted mean [SE]; BPI pain interference, 0-10 scale)
5.2 (0.19) vs. 5.4 (0.04) … and disorders related to chronic pain (e.g., arthritis, back-related pain, disc-related
pain, complicated … Mixed chronic pain (primarily non-cancer pain) Mixed Mean 47 53 NR NR NR NR NR NR NR 6; severity NR 761 … , gender, stage of chronification, severity of chronic pain, pain phenotype, pain duration, mean 24-hour
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-table-e5-2022-update_0.xlsx
January 01, 2022 - Cannabis cohort studies
PMID Author, Year Study Design Setting Pain Population Pain Condition Age Measure … Age, Years Female % Race, White % Race, Black % Race, Hispanic/Latino % Race, Asian % Race, Other % Pain … B
Pain Interference (Adjusted mean [SE]; BPI pain interference, 0-10 scale)
5.2 (0.19) vs. 5.4 (0.04) … , gender, stage of chronification, severity of chronic pain, pain phenotype, pain duration, mean 24-hour … pain intensity, current and past pain medications, comorbidities, comedications, and reasons for switching
-
effectivehealthcare.ahrq.gov/products/plant-based-chronic-pain-treatment
-
effectivehealthcare.ahrq.gov/products/pelvic-pain-therapies-future/research