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201. Cannabis-2023-Surv-Rep-4-Table-E-5 (xls file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cannabis-2023-surv-rep-4-table-E-5.xlsx
     January 01, 2023 - Cannabis cohort studies PMID Author, Year Study Design Setting Pain Population Pain Condition Age Measure … B Pain Interference (Adjusted mean [SE]; BPI pain interference, 0-10 scale) 5.2 (0.19) vs. 5.4 (0.04) … Mixed chronic pain (primarily non-cancer pain) Mixed Mean 47 53 NR NR NR NR NR NR NR 6; severity NR 761 … , gender, stage of chronification, severity of chronic pain, pain phenotype, pain duration, mean 24-hour … pain intensity, current and past pain medications, comorbidities, comedications, and reasons for switching

202. Cannabis-2022-Surv-Rep-4-Table-F5 (xls file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cannabis-2022-surv-rep-4-table-F5.xlsx
     January 01, 2022 - Cannabis cohort studies PMID Author, Year Study Design Setting Pain Population Pain Condition Age Measure … B Pain Interference (Adjusted mean [SE]; BPI pain interference, 0-10 scale) 5.2 (0.19) vs. 5.4 (0.04) … Mixed chronic pain (primarily non-cancer pain) Mixed Mean 47 53 NR NR NR NR NR NR NR 6; severity NR 761 … , gender, stage of chronification, severity of chronic pain, pain phenotype, pain duration, mean 24-hour … pain intensity, current and past pain medications, comorbidities, comedications, and reasons for switching

203. Making Healthcare Safer IV: Opioid Stewardship | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/mhs4-opioid-stewardship/protocol
     September 01, 2023 - See the MHS IV Prioritization Report for additional details. 1 The treatment of pain and suffering … The updated CDC Clinical Practice Guideline for Prescribing Opioids for Pain provides guidelines for … opioid dosage, opioid prescriptions, and overdose), and unintended consequences (e.g., increase in pain … The Effectiveness and Risks of Long-Term Opioid Treatment of Chronic Pain. … CDC Clinical Practice Guideline for Prescribing Opioids for Pain - United States, 2022.

204. Appendix-E-Table-E5 0 (xls file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/Appendix-E-Table-E5_0.xlsx
     November 04, 2021 - Cannabis cohort studies PMID Author, Year Study Design Setting Pain Population Pain Condition Age Measure … Age, years Female % Race, White % Race, Black % Race, Hispanic/Latino % Race, Asian % Race, other % Pain … Duration Measure (Mean, Median) Pain Duration, Months Psychiatric Comorbidity % N Interventions Dose … Treatment Duration (Weeks) Assessment Time Category Baseline Pain Variables Accounted for in Analyses … B Pain Interference (Adjusted mean [SE]; BPI pain interference, 0-10 scale) 5.2 (0.19) vs. 5.4 (0.04)

205. Cannabis-App-F5-Table-Surveillance-Report-2 0 0 (xls file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cannabis-app-f5-table-surveillance-report-2_0_0.xlsx
     February 16, 2022 - Cannabis cohort studies PMID Author, Year Study Design Setting Pain Population Pain Condition Age Measure … Age, Years Female % Race, White % Race, Black % Race, Hispanic/Latino % Race, Asian % Race, Other % Pain … Duration Measure (Mean, Median) Pain Duration, Months Psychiatric Comorbidity % N Interventions Dose … Treatment Duration (Weeks) Assessment Time Category Baseline Pain Variables Accounted for in Analyses … B Pain Interference (Adjusted mean [SE]; BPI pain interference, 0-10 scale) 5.2 (0.19) vs. 5.4 (0.04)

206. Comparative Effectiveness of Therapies for Women with Noncyclic Chronic Pelvic Pain (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/pelvic-pain_disposition-comments.pdf
     January 01, 2012 - Noncyclic Chronic Pelvic Pain Therapies for Women: Comparative Effectiveness. … Treatment is also fairly simple and their pain is gone or reduced.. … Public Reviewer #2 Discussion SI joint is a significant pain generator of chronic pelvic pain. … It is important to assure that the disease observed with pain is, in fact, the reason for the pain. … or non- cyclic / mixed chronic pelvic pain symptoms.

207. AHRQ Evidence-based Practice Center Program Research Gaps Summary: Primary Care (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/product/pdf/research-gap-primary-care-summary-table.pdf
     March 01, 2022 - (back pain, neck pain, other musculoskeletal pain, neuropathic pain, postsurgical pain, dental pain … , neuropathic pain, and neck pain). … We map the evidence for several acute pain conditions including postoperative pain, dental pain, neck … include postoperative postdischarge pain, acute back pain, acute neck pain, renal colic, and acute … • Certain acute pain conditions have many published systematic reviews: postoperative pain, pain

208. Disposition of Comments Report for The Effectiveness and Risks of Long-Term Opioid Treatment of Chronic Pain (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/chronic-pain-opioid-treatment_disposition-comments.pdf
     September 29, 2014 - Society/American Academy of Pain Medicine (Reference 9). … *treats pain that is less than severe (46.3%). … response to Relieving Pain in America, with a commitment to work together with many pain advocacy groups … treatments for people in pain. … Pain Med. 2012 Jan;13(1):87-95 4.

209. Hip Injuries and Disorders | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/health-topics/hip-injuries-and-disorders
     August 20, 2013 - Osteoarthritis can cause pain and limited motion. … Effectiveness Systematic Review Archived January 31, 2012 Noncyclic Chronic Pelvic Pain … Interventions for Hip Fracture Consumer Summary Archived May 17, 2011 Managing Pain … Archived October 19, 2010 Comparative Effectiveness of Treatments for Noncyclic Chronic Pelvic Pain … Women Research Protocol Archived December 9, 2009 Comparative Effectiveness of Pain

210. Draft Comment Form for Living Systematic Review on Cannabis and Other Plant-Based Treatments for Chronic Pain: 2025 Update | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/form/plant-based-chronic-pain-treatment/draft-comments
     April 01, 2025 - Comment Form for Living Systematic Review on Cannabis and Other Plant-Based Treatments for Chronic Pain … Comment Form for Living Systematic Review on Cannabis and Other Plant-Based Treatments for Chronic Pain … April 3, 2025 Living Systematic Review on Cannabis and Other Plant-Based Treatments for Chronic Pain … 2025 Update Draft Comments March 10, 2025 Peripheral Nerve Blocks for Postoperative Pain … https://effectivehealthcare.ahrq.gov/products/form/plant-based-chronic-pain-treatment/draft-comments

211. final Fibromyalgia CER protocol_3-31-14 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/fibromyalgia_research-protocol.pdf
     April 03, 2014 - , abnormal pain processing/heightened pain sensitivity, chronic fatigue, sleep disorders, and emotional … tachycardia, constipation, etc.) § Adverse effects from non-pharmaceutical treatments (such as muscle aches … , minor injuries or falls during or after exercise; soreness or aches from passive physical treatments … Pain assessment: global use of the Brief Pain Inventory. … The McGill Pain Questionnaire: major properties and scoring methods. Pain. 1975 Sep;1(3):277-99.

212. Prevention, Diagnosis, and Management of Opioids, Opioid Misuse and Opioid Use Disorder in Older Adults: Protocol (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/opioids-oa-protocol.pdf
     June 29, 2019 - to chronic pain (and to persistence of chronic pain) due to dysfunctional nociceptive processing (i.e … , raise the pain threshold in older adults, though once pain is experienced, older adults describe the … Age changes in pain perception: A systematic-review and meta-analysis of age effects on pain and tolerance … Pain and aging: the pain experience over the adult lifespan. … /pain/reports/index.html.

213. Evidence Summary for CER 239: Acute Treatments for Episodic Migraine (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/cer-239-acute-migraine-evidence-summary.pdf
     December 01, 2020 - (nonsteroidal anti- inflammatory drugs), dihydroergotamine, antiemetics, and acetaminophen, reduce pain … Some opioids may reduce pain of episodic migraine. … relief at 2 hours and increase the likelihood of being pain-free at 2 hours, 1 day, and at 1 week, … of being pain free at 2 hours, 1 day and 1 week (moderate 4 SOE). … (moderate to high SOE) and sustained pain free at 1 day and at 1 week (moderate to high SOE).

214. Prevention, Diagnosis, and Management of Opioids, Opioid Misuse and Opioid Use Disorder in Older Adults | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/opioids-older-adults/protocol
     August 01, 2020 - to chronic pain (and to persistence of chronic pain) due to dysfunctional nociceptive processing (i.e … , raise the pain threshold in older adults, though once pain is experienced, older adults describe the … Person-level pain and pain control. Person-level opioid use, misuse, and OUD. … Pain and aging: the pain experience over the adult lifespan. … /pain/reports/index.html .

215. Evidence-based Practice Center Technical Brief Protocol (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/pain-chronic_research-protocol.pdf
     July 28, 2010 - back pain, upper extremity pain disability, peripheral neuropathies, et cetera. … The goal of chronic pain treatment has evolved from eliminating pain to managing pain to an extent that … Patients with acute pain (e.g. pain less than 3 months and post-surgical pain) 3. … Journal of Pain 2006 Nov; 7(11):779-93. 3. American Pain Society. … American Pain Society. Pain Advocacy.

216. Diagnosis of Right Lower Quadrant Pain and Suspected Acute Appendicitis | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/appendicitis/research
     December 01, 2019 - Home Evidence Reports Diagnosis of Right Lower Quadrant Pain … SHARE: Diagnosis of Right Lower Quadrant Pain … Structured Abstract Background The reliable identification of patients with abdominal pain who need … Project Timeline Diagnosis of Right Lower Quadrant Pain and Suspected Acute Appendicitis Apr 17 … Internet Citation: Systematic Review: Diagnosis of Right Lower Quadrant Pain

217. Osteoarthritis | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/health-topics/osteoarthritis
     November 14, 2023 - It causes pain, swelling, and reduced motion in your joints. … Research Protocol April 27, 2017 Noninvasive, Nonpharmacological Treatment for Chronic Pain … An Update Systematic Review Archived February 1, 2013 Physical Therapy for Knee Pain … Systematic Review Archived November 6, 2012 Physical Therapy Interventions for Knee Pain … Research Protocol Archived March 2, 2011 Comparative Effectiveness of Physical Therapy for Knee Pain

218. Acute Treatments for Episodic Migraine | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/migraine-treatments/research
     January 01, 2023 - Some opioids may reduce pain of episodic migraine. … relief at 2 hours and increase the likelihood of being pain-free at 2 hours, 1 day, and at 1 week, and … Compared with placebo, triptans resolved pain at 2 hours and 1 day, and increased the risk of mild and … Compared with placebo, NSAIDs probably resolved pain at 2 hours and 1 day, and increased the risk of … Headache: The Journal of Head and Face Pain. 5 Jan 2023. [Epub ahead of print.] PMID: 36602191.

219. Nonopioid Pharmacologic Treatments for Chronic Pain: Appendix F2 (xls file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/nonopioid-chronic-pain-apf2_0.xlsx
     January 01, 2018 - Nonopioid Pharmacologic Treatments for Chronic Pain: Appendix F2 Appendix F2. … Sedation Serotonin Syndrome Serotonin Syndrome Serotonin Syndrome Serotonin Syndrome Author, Year Quality Pain … Retention Urinary Retention Urinary Retention Weight Gain Weight Gain Weight Gain Author, Year Quality Pain … Edema Sedation Sedation Sedation Sedation Weight Gain Weight Gain Weight Gain Author, Year Quality Pain … Capsaicin - Placebo-Controlled Trials WAE SAE Application Site Erythema Application Site Pain

220. Cannabis-2023-Update-Surv-Rep-3 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cannabis-2023-update-surv-rep-3.pdf
     January 01, 2023 - 1 Living Systematic Review on Cannabis and Other Plant-Based Treatments for Chronic Pain: 2023 … Living Systematic Review on Cannabis and Other Plant-Based Treatments for Chronic Pain: 2023 Update … Cannabis for chronic pain: cardiovascular safety in a nationwide Danish study. … Medicinal cannabis for Australian patients with chronic refractory pain including arthritis. … Br J Pain. 2023;17(2):206-17. doi: 10.1177/20494637221147115. PMID: 37057257.