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121. Systematic Review Update: Noninvasive Nonpharmacologic Treatment for Chronic Pain (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/nonpharm-treatment-chronic-pain-protocol.pdf
     December 11, 2018 - chronic pain conditions: low back pain, neck pain, osteoarthritis, fibromyalgia, and headache. … Management of Chronic Pain The overarching goal of chronic pain management is to relieve pain and improve … Pregnancy-related pain (e.g. back pain or pelvic pain) will be excluded; 2) inclusion of additional … ) conditions: low back pain, neck pain, osteoarthritis pain, fibromyalgia, or tension headache … : Low back pain • Adults with chronic, nonradicular low back pain KQ2: Neck pain • Adults with

122. Living Systematic Review on Cannabis and Other Plant-Based Treatments for Chronic Pain | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/plant-based-chronic-pain-treatment/protocol
     April 01, 2023 - of chronic pain? … of chronic pain? … are included in this category), musculoskeletal pain (including low-back pain), visceral pain, fibromyalgia … Prevalence of chronic pain and high-impact chronic pain among adults—United States, 2016. … / 2   exp arthralgia/ or exp back pain/ or exp headache/ or exp musculoskeletal pain/ or neck pain/

123. CER 220 Evidence Summary: Comparative Effectiveness of Analgesics To Reduce Acute Pain in the Prehospital Setting (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-220-analgesics-acute-pain-summary.pdf
     September 01, 2019 - insufficient prehospital pain relief. … Patient with moderate to severe, acute pain Health Outcomes Pain score Presence of pain Time … relief may reduce pain more and may reduce pain more quickly. … Low-dose ketamine improves pain relief in patients receiving intravenous opioids for acute pain in … Change in pain score after administration of analgesics for lower extremity fracture pain during hospitalization

124. Living Systematic Review on Plant-Based Treatment for Chronic Pain (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/plant-based-treatments-revised-protocol.pdf
     March 29, 2023 - of chronic pain? … are included in this category), musculoskeletal pain (including low-back pain), visceral pain, fibromyalgia … March 29, 2023 Table 1: Population Excluded subacute pain Added subacute pain Subacute pain, … exp arthralgia/ or exp back pain/ or exp headache/ or exp musculoskeletal pain/ or neck pain/ or exp … neuralgia/ or exp nociceptive pain/ or pain, intractable/ or fibromyalgia/ or myalgia/ 3 Pain/

125. Diagnosis of Right Lower Quadrant Pain and Suspected Acute Appendicitis | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/appendicitis/research-protocol
     December 01, 2019 - Imaging strategies for right lower quadrant pain in pregnancy. … specific) AND (abdome* OR abdomi*) AND pain) OR nsap OR RLQ pain OR (right AND lower AND (quarter OR … quadrant) AND pain) OR (acute AND abdominal AND pain) OR AAP) Primary studies (("Computerized tomography … specific) AND (abdome* OR abdomi*) AND pain) OR nsap OR RLQ pain OR (right AND lower AND (quarter OR … quadrant) AND pain) OR (acute AND abdominal AND pain) OR AAP) Systematic reviews (appendicitis OR

126. Methods Research Report: Testing a Machine Learning Tool for Facilitating Living Systematic Reviews of Chronic Pain Treatments (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/methods-report-testing-machine-learning-tool-chronic-pain.pdf
     November 01, 2020 - or "musculoskeletal pain" or osteoarthritis or "low back pain" or "neck pain" or "inflammatory pain … pain/ or neck pain/ or exp neuralgia/ or exp nociceptive pain/ or pain, intractable/ or fibromyalgia … or "musculoskeletal pain" or osteoarthritis or "low back pain" or "neck pain" or "inflammatory pain … or "musculoskeletal pain" or osteoarthritis or "low back pain" or "neck pain" or "inflammatory pain … pain.

127. For low-risk women delivering a full-term baby vaginally, what is the comparative effectiveness of the use of nitrous oxide for pain management versus an epidural or other pain management strategies. What are the effects on the birth… | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/get-involved/nominated-topics/for-low-risk-women-delivering-a-full-term-baby-vaginally-what-is-the-comparative-effectiveness-of-the-use-of-nitrous-oxide-for-pain-management-versus-an-epidural-or-other-pain-management-strategies-what-are-the-effects-on-th
     November 01, 2017 - management versus an epidural or other pain management strategies. … management versus an epidural or other pain management strategies. … management versus an epidural or other pain management strategies. … management versus an epidural or other pain management strategies. … for-low-risk-women-delivering-a-full-term-baby-vaginally-what-is-the-comparative-effectiveness-of-the-use-of-nitrous-oxide-for-pain-management-versus-an-epidural-or-other-pain-management-strategies-what-are-the-effects-on-th

128. Disposition of Comments: CER 227 Noninvasive Nonpharmacological Treatment for Chronic Pain (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/cer-227-noninvasive-nonpharm-chronic-pain-comments.pdf
     April 16, 2020 - We request that AHRQ clarify if a numeric pain scale is the only pain measure. … Pain score among others. … Effects of anger suppression on pain severity and pain behaviors among chronic pain patients: evaluation … Pain, 151(2), 280- 295. … PAIN, 158, 2354-2363.

129. Evidence Summary Comparative Effectiveness Review No. 250: Living Systematic Review on Cannabis and Other Plant-Based Treatments for Chronic Pain (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-other-plant-based-treatments-evidence-summary_0.pdf
     October 01, 2021 - Type(s) Mixed musculoskeletal, chronic non-cancer pain Chronic non-cancer pain NPP Baseline Pain … weeks to <6 months) THC to CBD Ratio Pain Response Effect Size (N Studies) [SOE]a Pain Severity … Prevalence of chronic pain and high-impact chronic pain among adults — United States, 2016. … Institute of Medicine Committee on Advancing Pain Research. … Cannabinoids and Pain: New Insights From Old Molecules.

130. Executive Summary - Living Systematic Review on Cannabis and Other Plant-Based Treatments for Chronic Pain: 2023 Update (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-executive-summary-2023-update.pdf
     January 01, 2023 - Type(s) Mixed musculoskeletal, chronic non- cancer pain Chronic non-cancer pain NPP Peripheral … NPP Peripheral neuropathic back pain Baseline Pain Score, Mean (Range)c 5.75 (4.56 to 7.00) … weeks to <6 months) Product, THC to CBD Ratio Pain Responsea Effect Size (N Studies) [SOE] Pain … (e.g., ≥30% improvement in pain). … studies on subacute pain.

131. App-F-Surv-Rept-1-Acute-Pain (xls file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/app-f-surv-rept-1-acute-pain.xlsx
     September 21, 2022 - F-1. RCT QA Table F-1. Risk of bias assessment for randomized controlled trials Author, Year (Full Citations Are Listed in Appendix C.) Randomization Adequate? Allocation Concealment Adequate? Groups Similar at Baseline? Outcome Assessors Masked? Care Provider Masked? Patient Masked? Reporting of Attrition, Crossove…

132. App-F1-Surv-Report-2-Nonopioid-Pharmacol-Chronic-Pain (xls file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/app-f1-surv-report-2-nonopioid-pharmacol-chronic-pain.xlsx
     September 20, 2022 - Pain severity for neuropathic pain Author, Year Quality Pain Population Drug Class 1 Drug Class 2 Drug … Pain response for neuropathic pain Author, Year Quality Pain Population Drug Class Drug Response Criteria … Pain severity for low back pain Author, Year Quality Pain Population Drug Class 1 Drug Class 2 Drug … Pain severity for chronic pelvic pain Author, Year Quality Pain Population Drug Class 1 Drug Class 2 … Pain response for chronic pelvic pain Author, Year Quality Pain Population Drug Class Drug Response

133. Care Coordination and Care Plans for Transitions Across Care Settings | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/care-coordination-plans/research
     November 01, 2022 - Purpose Transitions of care in people with pain … represent a period of increased vulnerability due to potential disruptions in pain management, which … Therefore, if effective in people with acute or chronic pain, transitional care interventions represent … However only one systematic review focused on patients with pain (specifically postsurgical patients) … The other nine systematic reviews did not report pain outcomes.

134. CER 220: Disposition of Comments Report for Comparative Effectiveness of Analgesics To Reduce Acute Pain in the Prehospital Setting (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-220-disposition-comments-analgesics-prehospital-setting.pdf
     September 03, 2019 - associated with acute pain”. … pain? … superimposed acute pain. … For the subgroup of traumatic pain, for the comparison of opioid versus APAP, change in pain scores … medications to treat acute pain.

135. Peripheral Nerve Blocks for Postoperative Pain Management in Cardiothoracic Surgery | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/peripheral-nerve-blocks/protocol
     May 01, 2024 - intensity scores, opioid consumption in morphine milliequivalents, pain trajectory, pain interference … intensity Opioid use Pain trajectory Pain interference Quality of recovery Health-related quality of … Rebound pain- increased pain relative to controls when the block subsides Outcomes not listed Studies … Postoperative pain experience: results from a national survey suggest postoperative pain continues to … The expanding role of chronic pain interventions in multimodal perioperative pain management: a narrative

136. Evidence Summary_Comparative Effectiveness Review No. 250_Living Systematic Review on Cannabis and Other Plant-Based Treatments for Chronic Pain: 2022 Update (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-evidence-summary-2022-update_0.pdf
     January 01, 2022 - Continued on page 2 2 Background and Purpose Chronic pain is defined as pain lasting … Type(s) Mixed musculoskeletal, chronic non-cancer pain Chronic non- cancer pain NPP Peripheral … weeks to <6 months) Product, THC to CBD Ratio Pain Response Effect Size (N Studies) [SOE] Pain … Prevalence of chronic pain and high- impact chronic pain among adults — United States, 2016. . … Kratom: A Cure for Chronic Pain or a Deadly Herb?

137. Executive summary_Comparative Effectiveness Review No. 250_Living Systematic Review on Cannabis and Other Plant-Based Treatments for Chronic Pain: 2024 Update (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-2024-surv-rep-update-executive-sum.pdf
     January 01, 2024 - Type(s) Mixed musculoskeletal, chronic noncancer pain Chronic noncancer pain NPP Peripheral … NPP Peripheral neuropathic back pain Baseline Pain Score, Mean (Range)c 5.75 (4.56 to 7.00) … weeks to <6 months) Product, THC to CBD Ratio Pain Responsea Effect Size (N Studies) [SOE] Pain … in pain). … Cannabis for chronic pain: cardiovascular safety in a nationwide Danish study.

138. App-F1-Surv-Report-3-Nonopioid-Pharmacol-Chronic-Pain (xls file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/app-f1-surv-report-3-nonopioid-pharmacol-chronic-pain.xlsx
     September 20, 2022 - Pain severity for neuropathic pain Author, Year Quality Pain Population Drug Class 1 Drug Class 2 Drug … Pain response for neuropathic pain Author, Year Quality Pain Population Drug Class Drug Response Criteria … Pain severity for low back pain Author, Year Quality Pain Population Drug Class 1 Drug Class 2 Drug … Pain severity for chronic pelvic pain Author, Year Quality Pain Population Drug Class 1 Drug Class 2 … Pain response for chronic pelvic pain Author, Year Quality Pain Population Drug Class Drug Response

139. Pharmacologic Management of Acute Pain by EMS in the Prehospital Setting Protocol Amendment (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/acute-pain-ems-protocol-amendment.pdf
     January 28, 2019 - acute pain.2 However, as many as 43% of individuals have insufficient prehospital pain relief.3 Reasons … o Studies that target mild pain or non-zero pain to administer analgesics will be excluded. … o KQ1a, 2a, 3a, 4a: Age, source of pain, severity of pain, medical condition (including chronic pain … Health outcomes Pain score Presence of pain Time to analgesic effect Memory of pain (KQ … and non- traumatic pain.

140. App-F1-Surv-Report-1-Nonopioid-Pharmacol-Chronic-Pain (xls file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/app-f1-surv-report-1-nonopioid-pharmacol-chronic-pain.xlsx
     September 20, 2022 - Pain severity for neuropathic pain Author, Year Quality Pain Population Drug Class 1 Drug Class 2 Drug … Pain response for neuropathic pain Author, Year Quality Pain Population Drug Class Drug Response Criteria … Function outcomes for neuropathic pain Author, Year Quality Pain Population Drug Class 1 Drug Class … Pain severity for low back pain Author, Year Quality Pain Population Drug Class 1 Drug Class 2 Drug … Pain response for low back pain Author, Year Quality Pain Population Drug Class Drug Response Criteria