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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/healthy-diet-and-physical-activity-for-cvd-prevention-adults-without-cvd-risk-factors-behavioral-counseling
June 04, 2020 - physical activity, and reduce sedentary behavior improve cardiovascular disease (CVD) and related health outcomes … improve diet, increase physical activity, and reduce sedentary behavior improve intermediate behavioral outcomes … What is the relationship between intermediate behavioral outcomes (i.e., diet and physical activity) … and health outcomes (i.e., cardiovascular morbidity and mortality, all-cause mortality, and quality of … levels, and fasting glucose levels) and health outcomes?
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/healthy-lifestyle-and-physical-activity-for-cvd-prevention-adults-without-known-risk-factors-behavioral-counseling
June 04, 2020 - physical activity, and reduce sedentary behavior improve cardiovascular disease (CVD) and related health outcomes … What is the relationship between intermediate behavioral outcomes (i.e., diet and physical activity) … and health outcomes (i.e., cardiovascular morbidity and mortality, all-cause mortality, and quality of … levels, and fasting glucose levels) and health outcomes? … (e.g., functioning or well-being)
KQ 2: Intermediate outcomes
Blood pressure
Total, low-density
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www.uspreventiveservicestaskforce.org/uspstf/document/draft-research-plan/lipid-disorders-children-adolescents-screening
May 13, 2021 - (cardiovascular disease events * or mortality) or improve intermediate outcomes (serum lipid levels … (cardiovascular disease events * or mortality) or improve intermediate outcomes (serum lipid levels … What is the association between childhood and adolescent intermediate outcomes (serum lipid levels and … atherosclerosis markers) and adult health outcomes (adult cardiovascular disease events or mortality … stroke
CVD mortality
All-cause mortality
Intermediate outcomes:
Serum lipid levels (TC
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www.uspreventiveservicestaskforce.org/uspstf/document/draft-research-plan/breast-cancer-medication-use-reduce-risk
December 28, 2023 - be described with respect to factors that can contribute to variability in intervention access and outcomes … medications to prevent primary breast cancer
Use of medications for treatment or prevention of other outcomes … mortality; all-cause mortality; and quality of life
KQ 2 (Harms): Adverse quality of life and health outcomes … Fractures
Ophthalmologic disorders
Genitourinary outcomes
Thromboembolic events
Cardiovascular … events
Risk of other cancers
Adverse outcomes related to quality of life
Noninvasive breast
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/healthy-diet-and-physical-activity-counseling-adults-with-high-risk-of-cvd
September 13, 2018 - What is the relationship between behavioral outcomes (e.g., diet and physical activity) and health outcomes … What is the relationship between intermediate outcomes (e.g., blood pressure, lipid levels, blood glucose … , and body mass index) and health outcomes? … (e.g., functioning or well-being)
KQ 2: Intermediate outcomes
Blood pressure
Total, low-density … Dietary intake or patterns
Physical activity
Sedentary behavior
KQ 4: Adverse outcomes
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www.uspreventiveservicestaskforce.org/uspstf/document/draft-research-plan/healthy-weight-and-weight-gain-during-pregnancy-behavioral-counseling-interventions
April 26, 2018 - Do interventions to limit excess gestational weight gain lead to improved health outcomes among pregnant … interventions to reduce prepregnancy weight in women who are overweight or obese lead to improved health outcomes … What is the association between gestational weight gain and adverse maternal and infant outcomes? … What is the association between high prepregnancy BMI and risk of adverse maternal and infant outcomes … is the association between reduction in prepregnancy weight and risk of adverse maternal and infant outcomes
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www.uspreventiveservicestaskforce.org/uspstf/document/draft-research-plan/autism-spectrum-disorder-young-children-1
February 25, 2021 - Developmental, functional, and quality of life outcomes? … interventions targeting young children with ASD improve developmental, functional, and quality of life outcomes … initiation (by age and in relation to the establishment of an ASD diagnosis) associated with ASD-related outcomes … (i.e., developmental, functional, and quality of life outcomes)? … , family distress, false reassurance, and opportunity cost)
KQ 4: Developmental and functional outcomes
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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/hypertensive-disorders-pregnancy-screening
September 19, 2023 - Racial disparities in adverse pregnancy outcomes and psychosocial stress. … Preeclampsia outcomes at delivery and race. … Racial/ethnic disparities in obstetric outcomes and care: prevalence and determinants. … The questions are depicted by linkages that relate to interventions and outcomes. … Outcomes: Study did not have relevant outcomes or had incomplete outcomes.
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/child-maltreatment-primary-care-interventions
November 27, 2018 - Several trials presented outcomes at multiple periods. … Results were not statistically significant for 7 outcomes. … Other Developmental Outcomes. … Furthermore, interpretation of some outcomes can be challenging. … outcomes (such as interpregnancy interval).
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/child-maltreatment-primary-care-interventions-november-2018
November 27, 2018 - Several trials presented outcomes at multiple periods. … Results were not statistically significant for 7 outcomes. … Other Developmental Outcomes. … Furthermore, interpretation of some outcomes can be challenging. … outcomes (such as interpregnancy interval).
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/drug-use-illicit-primary-care-interventions-for-children-and-adolescents
August 30, 2018 - referable interventions to prevent drug use in children, adolescents, and young adults improve health outcomes … or other related outcomes? … referable interventions to prevent drug use in children, adolescents, and young adults improve drug use outcomes … KQ 1 (H ealth, social, educational, and other outcomes):
Health outcomes:
All-cause mortality … KQ 2 (Behavioral outcomes):
Drug use ( required ) (self-reported and/or biologic measures):
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan98/statin-use-in-adults-preventive-medication
May 02, 2014 - Analytic Framework
Screening for Dyslipidemia to Improve Cardiovascular Outcomes … Use of Statins to Improve Cardiovascular Outcomes
Text Description
Figure 2. … in adults ages 21 to 39 years on intermediate outcomes (e.g., lipid levels or atherosclerosis)? … Include
Exclude
Screening for Dyslipidemia to Improve Cardiovascular Outcomes … not listed as included
KQ 2: Adverse outcomes not associated with screening
KQ 3: Outcomes
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan98/statin-use-in-adults-preventive-medication-november-2016
May 02, 2014 - Use of Statins to Improve Cardiovascular Outcomes
Text Description
Figure 2. … in adults ages 21 to 39 years on intermediate outcomes (e.g., lipid levels or atherosclerosis)? … Use of Statins to Improve Cardiovascular Outcomes
What is the comparative accuracy of different … Include
Exclude
Screening for Dyslipidemia to Improve Cardiovascular Outcomes … not listed as included
KQ 2: Adverse outcomes not associated with screening
KQ 3: Outcomes
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www.uspreventiveservicestaskforce.org/uspstf/draft-recommendation/gestational-diabetes-mellitus-screening1
February 16, 2021 - Few trials examined longer-term maternal or childhood outcomes. … Hyperglycemia and adverse pregnancy outcomes. N Engl J Med . 2008;358(19):1991-2002. 4. … Hyperglycaemia and risk of adverse perinatal outcomes: systematic review and meta-analysis. … Effect of treatment of gestational diabetes mellitus on pregnancy outcomes. … There is inadequate direct evidence that screening for GDM improves health outcomes.
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www.uspreventiveservicestaskforce.org/uspstf/draft-recommendation/gestational-diabetes-screening
February 16, 2021 - Few trials examined longer-term maternal or childhood outcomes. … Hyperglycemia and adverse pregnancy outcomes. N Engl J Med . 2008;358(19):1991-2002. 4. … Hyperglycaemia and risk of adverse perinatal outcomes: systematic review and meta-analysis. … Effect of treatment of gestational diabetes mellitus on pregnancy outcomes. … There is inadequate direct evidence that screening for GDM improves health outcomes.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/UXw277rnvJ8e_Dfsh4V3K3
July 26, 2022 - For intermediate health outcomes (KQ2) and behavioral
outcomes (KQ3), random-effects meta-analyses were … Benefits on Intermediate CVD Outcomes
Key Question 2. … : Study did not report relevant outcomes. … 15 (13)
2: Intermediate outcomes 43 (38)
3: Behavioral outcomes 109 (97)
4: Harms 23 (20)
Study … Third, given that behavioral outcomes were the
primary outcomes in almost all the included studies, there
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/blood-pressure-in-children-and-adolescents-hypertension-screening
November 01, 2018 - Framework
*Intermediate outcomes … between high blood pressure in children and adolescents and high blood pressure and other intermediate outcomes … What are the associations between intermediate outcomes related to high blood pressure in children and … adolescents and health outcomes related to high blood pressure in children, adolescents, and adults? … KQs 1, 7 (Hypertension-related outcomes):
Severe visual impairment
End-stage renal disease
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/cognitive-impairment-in-older-adults-screening
October 19, 2017 - KQs 1, 4: Decisionmaking outcomes:
For patients and family/caregivers: Health care, legal, and … : (a priori defined as primary or secondary outcomes in the trial)
Health-related quality of life … ), and psychological harms (depression, anxiety)
KQs 1, 4:
Decisionmaking outcomes: Cost-related … outcomes
Patient-related outcomes: Cost-related outcomes; patient satisfaction (other than health-related … quality of life)
Societal outcomes: Cost-related outcomes
KQ 2: Cost-related outcomes
KQs 3,
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www.uspreventiveservicestaskforce.org/uspstf/document/draft-research-plan/vitamin-supplementation-to-prevent-cvd-and-cancer-preventive-medication
May 23, 2019 - Be Systematically Reviewed
What is the efficacy of multivitamin supplementation on health outcomes … efficacy of supplementation with single nutrients or functionally related nutrient pairs on health outcomes … factors (e.g., high blood pressure, abnormal lipid levels, or type 2 diabetes mellitus) and precancerous outcomes … Comparisons
Placebo or no intervention
Supplementation with other vitamins or minerals
Outcomes … glucose measures)
Timing
All-cause mortality: Minimum of 1 year of followup
All other outcomes
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan31/iron-deficiency-anemia-in-pregnant-women-screening-and-supplementation
July 15, 2013 - the benefits of routine iron supplementation on maternal and infant intermediate and clinical health outcomes … KQ 1: Maternal outcomes : Caesarian section rates, preterm delivery, postpartum depression; incidence … deficiency anemia; incidence of iron deficiency; hematologic indices and ferritin levels
Infant outcomes … KQs 1, 3: Maternal outcomes : Caesarian section rates, preterm delivery, postpartum depression … KQ 3: Maternal outcomes : Incidence of iron deficiency anemia; incidence of iron deficiency; hematologic