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  1. www.uspreventiveservicestaskforce.org/uspstf/sites/default/files/inline-files/prevmethods.pdf
    December 01, 2010 - focuses on specific diseases, well-defined preventive interventions, and evidence of improved health outcomes … ; older adults are not often rep- resented in clinical trials; and important outcomes may not be measured … Often, these are discrete and well-understood outcomes, such as all-cause or cause-specific mortality … , including im- provements of global health outcomes, such as quality of life. … Analytic framework for USPSTF review on interventions to reduce falls and fall-related outcomes.
  2. www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan37/vitamin-d-deficiency-screening
    March 24, 2014 - What is the association between serum 25-hydroxyvitamin D levels and health outcomes? … What is the effect of vitamin D (with or without calcium) on intermediate outcomes (e.g., blood pressure … KQs 1, 3: Health outcomes include: Decreased morbidity from osteoporosis/fractures, falls, … include: Mortality Renal outcomes (e.g., stones) Soft tissue calcification Adverse events … ) Intermediate physiological outcomes (examined as contextual question) Behavioral changes (e.g.,
  3. www.uspreventiveservicestaskforce.org/apps/gradedef.jsp
    July 01, 2012 - These studies assess the effects of the preventive service on health outcomes. … More information may allow estimation of effects on health outcomes … The USPSTF found at least fair evidence that [the service] improves important health outcomes … Fair: Evidence is sufficient to determine effects on health outcomes, but the strength of the evidence … Poor: Evidence is insufficient to assess the effects on health outcomes because of limited number or
  4. www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan37/vitamin-d-deficiency-screening-november-2014
    March 24, 2014 - What is the association between serum 25-hydroxyvitamin D levels and health outcomes? … What is the effect of vitamin D (with or without calcium) on intermediate outcomes (e.g., blood pressure … KQs 1, 3: Health outcomes include: Decreased morbidity from osteoporosis/fractures, falls, … include: Mortality Renal outcomes (e.g., stones) Soft tissue calcification Adverse events … ) Intermediate physiological outcomes (examined as contextual question) Behavioral changes (e.g.,
  5. www.uspreventiveservicestaskforce.org/uspstf/document/draft-research-plan/tobacco-smoking-cessation-in-adults-including-pregnant-women-interventions
    March 15, 2018 - Systematically Reviewed Do tobacco cessation interventions improve mortality, morbidity, and other health outcomes … thiocyanate) Population-based smoking rates (i.e., not based on study sample but on underlying population) Outcomes … KQ 1 (health and other outcomes ) : Health outcomes: All-cause mortality Tobacco-related mortality … Perinatal morbidity/mortality Dental/oral health Quality of life, as measured by validated tools Other outcomes … : Health care utilization KQ 2 (behavioral outcomes ) : Tobacco cessation/tobacco abstinence (continuous
  6. www.uspreventiveservicestaskforce.org/uspstf/document/draft-research-plan/hearing-loss-in-older-adults-screening1
    November 08, 2018 - Does screening for hearing loss in asymptomatic adults age 50 years or older improve health outcomes? … How efficacious are interventions for screen-detected hearing loss in improving health outcomes in adults … Does adherence to hearing aid use improve health outcomes in adults with screen-detected hearing loss … Do interventions to improve hearing aid adherence improve health outcomes? … KQs 3, 5: False-positive results, labeling, anxiety, and any other significant harms KQs 1, 4: Outcomes
  7. www.uspreventiveservicestaskforce.org/uspstf/document/RecommendationStatementFinal/child-maltreatment-primary-care-interventions
    March 19, 2024 - , included clinical professionals (eg, nurses), and compared interventions with usual care. 1 , 21 Outcomes … ) or hospital, and failure to provide for the child’s medical needs. 1 , 21 Interpretation of some outcomes … with the control group (adjusted odds ratio, 1.85 [95% CI, 1.02-2.85]). 1 , 21 , 25 Intermediate Outcomes … reported some benefit in study-specific outcomes; however, study construction and outcomes varied substantially … Evidence of benefit on child maltreatment outcomes is limited and inconsistent.
  8. www.uspreventiveservicestaskforce.org/uspstf/about-uspstf/reports-congress/twelfth-annual-report-congress-high-priority-evidence-gaps-clinical-preventive-services
    January 01, 2022 - The Task Force recognizes that disparities persist in healthcare and health outcomes based on age, race … equity by highlighting research gaps related to healthy behaviors, high-risk populations, and health outcomes … Address the effects of screening on health outcomes in children and adolescent populations reflective … lifestyle interventions and medical treatments for screen-detected prediabetes and diabetes on health outcomes … primary care settings and determine how referral to dental care by primary care clinicians affects caries outcomes
  9. www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/menopausal-hormone-therapy-preventive-medication
    May 27, 2021 - are not FDA-approved Control interventions Placebo, no treatment Active comparator Outcomes … to chronic conditions of interest) Functional capacity Urinary incontinence Diabetes Any outcomes … that are not health outcomes of chronic conditions associated with HT; intermediate outcomes, such as … : RCTs Controlled clinical trials Systematic reviews For outcomes or subgroups with no evidence … Several comments requested that the USPSTF include intermediate outcomes, such as cholesterol levels
  10. www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/blood-pressure-in-children-and-adolescents-hypertension-screening
    November 10, 2020 - in childhood and health outcomes in adulthood, however, is unclear. … Studies reporting multiple outcomes may have been assigned different quality ratings for different outcomes … None of the studies provided efficacy outcomes beyond 4 weeks. … The questions are depicted by linkages that relate interventions to outcomes. … A dashed line indicates a health outcome that precedes subsequent outcomes.
  11. www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/healthy-weight-and-weight-gain-during-pregnancy-behavioral-counseling-interventions
    May 25, 2021 - Main Outcomes and Measures: Gestational weight–related outcomes; maternal and infant morbidity and mortality … Outcomes were classified as weight-related intermediate outcomes (GWG, exceeding or adhering to NAM GWG … For dichotomous outcomes with at least 5 trials, sufficient sample size, and comparable outcomes, risk … Benefits for Health Outcomes Key Question 1a. … twelve-month outcomes of the Fit for Delivery randomized trial.
  12. www.uspreventiveservicestaskforce.org/uspstf/document/draft-research-plan/perinatal-depression-interventions-to-prevent
    February 23, 2023 - Do interventions to prevent perinatal depression improve health outcomes … limited to no more than 15 minutes of information) Placebo required for medication trials   Outcomes … KQ 1: Maternal health outcomes: Depression incidence or symptoms (required) Suicide deaths … functioning Psychiatric hospital admissions Marital discord and family function Infant/child health outcomes …   Withdrawals due to adverse events in trials of treatment benefit KQ 1:  Maternal behavioral outcomes
  13. www.uspreventiveservicestaskforce.org/uspstf/behavioral-counseling-interventions-evidence-based-approach-figure-1
    November 01, 2013 - Does Changing Individual Health Behavior Improve Health Outcomes? … search and evaluation to answer the overall question, "Does changing individual behavior improve health outcomes … The figure "reads" from left to right and connects a series of boxes (containing population groups or outcomes … questions are to be answered to understand each action or association between population groups and outcomes … Below the line is an oval labeled "Adverse Effects" and another box labeled "Other Positive Outcomes.
  14. www.uspreventiveservicestaskforce.org/uspstf/about-uspstf/methods-and-processes/behavioral-counseling-research-and-evidence-based-practice-recommendations-us-preventive-services-task-force-perspectives
    March 01, 2014 - linking behavior changes to health outcomes. … ; and use of existing data sets to link behavior change and clinical outcomes. … and assessment, and linking behavior changes to health outcomes. … and by varying validity of measured and reported outcomes. … were primary or secondary outcomes or whether trials selectively reported outcomes. 14 The evidence
  15. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary22/iron-deficiency-anemia-in-pregnant-women-screening-and-supplementation
    March 30, 2015 - Health outcomes included long- or short-term maternal and infant morbidity (including birth outcomes) … infant health outcomes. … Maternal clinical outcomes Limited evidence showing improved clinical outcomes 5 RCTs Outcomes … A dotted line leads from the intermediate outcomes to the health outcomes examined, representing the … Health outcomes include maternal and infant morbidity and mortality, including birth outcomes and quality
  16. www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan154/healthful-diet-and-physical-activity-for-cardiovascular-disease-prevention-in-adults-without-known-risk-factors-behavioral-counseling
    May 14, 2015 - improve diet, increase physical activity, and reduce sedentary behavior may result in improved health outcomes … to improve diet, increase physical activity, and/or reduce sedentary behavior improve intermediate outcomes … What is the relationship between behavioral outcomes (i.e., healthful diet, physical activity, and sedentary … that behavioral counseling interventions have an effect and health outcomes? … (i.e., physical activity, dietary intake or patterns, sedentary behavior) KQ 4: Adverse outcomes,
  17. www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan154/healthful-diet-and-physical-activity-for-cardiovascular-disease-prevention-in-adults-without-known-risk-factors-behavioral-counseling-july-2017
    May 14, 2015 - improve diet, increase physical activity, and reduce sedentary behavior may result in improved health outcomes … to improve diet, increase physical activity, and/or reduce sedentary behavior improve intermediate outcomes … that behavioral counseling interventions have an effect and health outcomes? … KQ 1: Health outcomes (i.e., CVD events [stroke, myocardial infarction], cardiovascular and all-cause … (i.e., physical activity, dietary intake or patterns, sedentary behavior) KQ 4: Adverse outcomes,
  18. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/skin-cancer-counseling
    March 20, 2018 - For KQ1, intermediate outcomes were defined as sunburn, nevi, and actinic keratosis, and health outcomes … Behavioral outcomes for KQ2 could be parent- or self-reported outcomes that related to sun protection … Effects of Interventions on Health Outcomes Key Question 1. … Outcomes: Study did not have relevant outcomes or had incomplete outcomes. … No studies reported skin cancer outcomes.
  19. www.uspreventiveservicestaskforce.org/home/getfilebytoken/TkAWAdFHNkePeKEqUcH8AL
    May 25, 2021 - MAIN OUTCOMES AND MEASURES Gestational weight–related outcomes; maternal and infant morbidity and mortality … Outcomes were classified as weight-related intermediate outcomes (GWG, exceeding or adhering to NAM GWG … For dichotomous outcomes with at least 5 trials, sufficient sample size, and comparable outcomes, risk … Benefits for Health Outcomes Key Question 1a. … twelve-month outcomes of the Fit for Delivery randomized trial.
  20. www.uspreventiveservicestaskforce.org/home/getfilebytoken/Qw-BbMqbtS--vonRX4qJe-
    February 01, 2004 - Even in the absence of screening, the current treatment interventions provide very favorable health outcomes … Clinical Considerations • The low incidence of testicular cancer and favorable outcomes in the absence … The USPSTF found at least fair evidence that [the service] can improve health outcomes but concludes … Fair: Evidence is sufficient to determine effects on health outcomes, but the strength of the evidence … Poor: Evidence is insufficient to assess the effects on health outcomes because of limited number or

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