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  1. www.uspreventiveservicestaskforce.org/uspstf/document/draft-research-plan/healthy-diet-and-physical-activity-for-cvd-prevention-adults-without-cvd-risk-factors-behavioral-counseling
    February 20, 2020 - physical activity, and reduce sedentary behavior improve cardiovascular disease (CVD) and related health outcomes … What is the relationship between behavioral outcomes (i.e., diet and physical activity) and health outcomes … levels, and fasting glucose levels) and health outcomes? … KQ 1: Health outcomes Cardiovascular events and related morbidity (e.g., stroke, myocardial … (e.g., functioning or well-being) KQ 2: Intermediate outcomes Blood pressure Total, low-density
  2. www.uspreventiveservicestaskforce.org/uspstf/document/draft-research-plan/healthy-diet-and-physical-activity-for-cardiovascular-disease-prevention-adults-without-known-risk-factors-behavioral-counseling
    February 20, 2020 - physical activity, and reduce sedentary behavior improve cardiovascular disease (CVD) and related health outcomes … What is the relationship between behavioral outcomes (i.e., diet and physical activity) and health outcomes … levels, and fasting glucose levels) and health outcomes? … KQ 1: Health outcomes Cardiovascular events and related morbidity (e.g., stroke, myocardial … (e.g., functioning or well-being) KQ 2: Intermediate outcomes Blood pressure Total, low-density
  3. www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/hepatitis-b-virus-infection-screening
    December 15, 2020 - , and the association between achieving intermediate outcomes after antiviral therapy and clinical outcomes … clinical outcomes. … transmission, extrahepatic outcomes, or harms). … improve clinical outcomes. … Preventive Services Task Force: linking intermediate outcomes and health outcomes in prevention.
  4. www.uspreventiveservicestaskforce.org/home/getfilebytoken/QTkyWhfQHqFUy4He2B6HU4
    April 09, 2024 - Although the health equity gaps focus on Black women because they have the poorest health outcomes from … Direct/ Indirect Pathway† Type of Gap Study Characteristics Population Intervention/ Comparison Outcomes … Direct/ Indirect Pathway† Type of Gap Study Characteristics Population Intervention/ Comparison Outcomes … Studies are needed that report health outcomes such as quality of life and breast cancer– associated … Studies are needed that report outcomes such as the rates of advanced breast cancers diagnosed across
  5. www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/healthy-diet-and-physical-activity-for-cvd-prevention-adults-without-known-risk-factors-behavioral-counseling
    June 04, 2020 - physical activity, and reduce sedentary behavior improve cardiovascular disease (CVD) and related health outcomes … improve diet, increase physical activity, and reduce sedentary behavior improve intermediate behavioral outcomes … What is the relationship between intermediate behavioral outcomes (i.e., diet and physical activity) … and health outcomes (i.e., cardiovascular morbidity and mortality, all-cause mortality, and quality of … levels, and fasting glucose levels) and health outcomes?
  6. www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/healthy-diet-and-physical-activity-for-cvd-prevention-adults-without-cvd-risk-factors-behavioral-counseling
    June 04, 2020 - physical activity, and reduce sedentary behavior improve cardiovascular disease (CVD) and related health outcomes … improve diet, increase physical activity, and reduce sedentary behavior improve intermediate behavioral outcomes … What is the relationship between intermediate behavioral outcomes (i.e., diet and physical activity) … and health outcomes (i.e., cardiovascular morbidity and mortality, all-cause mortality, and quality of … levels, and fasting glucose levels) and health outcomes?
  7. www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/healthy-lifestyle-and-physical-activity-for-cvd-prevention-adults-without-known-risk-factors-behavioral-counseling
    June 04, 2020 - physical activity, and reduce sedentary behavior improve cardiovascular disease (CVD) and related health outcomes … What is the relationship between intermediate behavioral outcomes (i.e., diet and physical activity) … and health outcomes (i.e., cardiovascular morbidity and mortality, all-cause mortality, and quality of … levels, and fasting glucose levels) and health outcomes? … (e.g., functioning or well-being) KQ 2: Intermediate outcomes Blood pressure Total, low-density
  8. www.uspreventiveservicestaskforce.org/home/getfilebytoken/4NUuvS6nmzTdBgjBg3ELkE
    January 01, 2020 - Limitation: Sparse reporting of patient health outcomes, longer- term follow-up of outcomes, and harms … (question 1), intermedi- ate cardiovascular disease–related outcomes (question 2), behavioral outcomes … Pooled Effect Sizes for Intermediate Cardiovascular Health Outcomes, by Intervention Type Outcomes, … for fasting glucose and weight outcomes; sparse reporting of outcomes beyond 24 mo; limited number of … Trials reporting only behavi- oral outcomes (no intermediate outcomes) found small but significant improvement
  9. www.uspreventiveservicestaskforce.org/uspstf/document/draft-research-plan/lipid-disorders-children-adolescents-screening
    May 13, 2021 - (cardiovascular disease events * or mortality) or improve intermediate outcomes (serum lipid levels … (cardiovascular disease events * or mortality) or improve intermediate outcomes (serum lipid levels … What is the association between childhood and adolescent intermediate outcomes (serum lipid levels and … atherosclerosis markers) and adult health outcomes (adult cardiovascular disease events or mortality … stroke CVD mortality All-cause mortality Intermediate outcomes: Serum lipid levels (TC
  10. www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/healthy-diet-and-physical-activity-counseling-adults-with-high-risk-of-cvd
    September 13, 2018 - What is the relationship between behavioral outcomes (e.g., diet and physical activity) and health outcomes … What is the relationship between intermediate outcomes (e.g., blood pressure, lipid levels, blood glucose … , and body mass index) and health outcomes? … (e.g., functioning or well-being) KQ 2: Intermediate outcomes Blood pressure Total, low-density … Dietary intake or patterns Physical activity Sedentary behavior KQ 4: Adverse outcomes
  11. www.uspreventiveservicestaskforce.org/uspstf/document/draft-research-plan/chronic-kidney-disease-screening
    January 19, 2023 - chronic kidney disease (CKD), * what are the effects of screening for CKD vs. no screening on clinical outcomes … Among adults with CKD stages 1–3, † what are the effects of treatment on clinical outcomes? … Progression to stage 5 CKD (end-stage renal disease, including renal replacement) Composite renal outcomes … 3, 3a: Sensitivity Specificity Area under the receiver operating characteristic curve Outcomes … ; KDOQI=Kidney Disease Outcomes Quality Initiative.
  12. www.uspreventiveservicestaskforce.org/uspstf/document/draft-research-plan/breast-cancer-medication-use-reduce-risk
    December 28, 2023 - be described with respect to factors that can contribute to variability in intervention access and outcomes … medications to prevent primary breast cancer Use of medications for treatment or prevention of other outcomes … mortality; all-cause mortality; and quality of life KQ 2 (Harms): Adverse quality of life and health outcomes … Fractures Ophthalmologic disorders Genitourinary outcomes Thromboembolic events Cardiovascular … events Risk of other cancers Adverse outcomes related to quality of life Noninvasive breast
  13. www.uspreventiveservicestaskforce.org/uspstf/recommendation/iron-deficiency-anemia-in-pregnant-women-screening-and-supplementation
    August 20, 2024 - deficiency and iron deficiency anemia in pregnant persons to prevent adverse maternal and infant health outcomes … harms of routine iron supplementation in pregnant persons to prevent adverse maternal and infant health outcomes … iron deficiency with or without anemia during pregnancy to prevent adverse maternal and infant health outcomes … Evidence of intermediate outcomes in infants was limited to 2 trials 20 , 31 (n = 12,943) reporting … Micronutrient supplementation and pregnancy outcomes: double-blind randomized controlled trial in China
  14. www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan98/statin-use-in-adults-preventive-medication
    May 02, 2014 - Analytic Framework Screening for Dyslipidemia to Improve Cardiovascular Outcomes … Use of Statins to Improve Cardiovascular Outcomes Text Description Figure 2. … in adults ages 21 to 39 years on intermediate outcomes (e.g., lipid levels or atherosclerosis)? … Include Exclude Screening for Dyslipidemia to Improve Cardiovascular Outcomes … not listed as included KQ 2: Adverse outcomes not associated with screening KQ 3: Outcomes
  15. www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan98/statin-use-in-adults-preventive-medication-november-2016
    May 02, 2014 - Use of Statins to Improve Cardiovascular Outcomes Text Description Figure 2. … in adults ages 21 to 39 years on intermediate outcomes (e.g., lipid levels or atherosclerosis)? … Use of Statins to Improve Cardiovascular Outcomes What is the comparative accuracy of different … Include Exclude Screening for Dyslipidemia to Improve Cardiovascular Outcomes … not listed as included KQ 2: Adverse outcomes not associated with screening KQ 3: Outcomes
  16. www.uspreventiveservicestaskforce.org/uspstf/document/draft-research-plan/autism-spectrum-disorder-young-children-1
    February 25, 2021 - Developmental, functional, and quality of life outcomes? … interventions targeting young children with ASD improve developmental, functional, and quality of life outcomes … initiation (by age and in relation to the establishment of an ASD diagnosis) associated with ASD-related outcomes … (i.e., developmental, functional, and quality of life outcomes)? … , family distress, false reassurance, and opportunity cost) KQ 4: Developmental and functional outcomes
  17. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/child-maltreatment-primary-care-interventions
    November 27, 2018 - Several trials presented outcomes at multiple periods. … Results were not statistically significant for 7 outcomes. … Other Developmental Outcomes. … Furthermore, interpretation of some outcomes can be challenging. … outcomes (such as interpregnancy interval).
  18. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/child-maltreatment-primary-care-interventions-november-2018
    November 27, 2018 - Several trials presented outcomes at multiple periods. … Results were not statistically significant for 7 outcomes. … Other Developmental Outcomes. … Furthermore, interpretation of some outcomes can be challenging. … outcomes (such as interpregnancy interval).
  19. www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/cognitive-impairment-in-older-adults-screening
    October 19, 2017 - KQs 1, 4: Decisionmaking outcomes: For patients and family/caregivers: Health care, legal, and … : (a priori defined as primary or secondary outcomes in the trial) Health-related quality of life … ), and psychological harms (depression, anxiety) KQs 1, 4: Decisionmaking outcomes: Cost-related … outcomes Patient-related outcomes: Cost-related outcomes; patient satisfaction (other than health-related … quality of life) Societal outcomes: Cost-related outcomes KQ 2: Cost-related outcomes KQs 3,
  20. www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/hepatitis-c-screening
    December 21, 2017 - What is the effectiveness of currently recommended antiviral treatments in improving health outcomes … What is the effect of antiviral treatments on behavioral outcomes? … , including intermediate outcomes Setting U.S. primary care, obstetrics/gynecology, emergency … Perinatal transmission of HCV infection Other outcomes Settings U.S. labor and delivery … will be included for Contextual Question 3 Histologic outcomes, liver function tests Setting

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