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www.uspreventiveservicestaskforce.org/home/getfilebytoken/XGHwLrLfb_78ymEUwGF6jR
March 19, 2024 - The evidence was inconclusive for all other outcomes
because of the limited number of trials on each … A subset of trials reported outcomes at 1 or more
time points after the first analysis of results. … examine the association between social
determinants of health and child maltreatment outcomes? … Additionally, interpre-
tation of some outcomes could be challenging. … problems,
school-related conduct outcomes, and infant social and emotional adjustment.
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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/hepatitis-b-virus-infection-screening
December 15, 2020 - , and the association between achieving intermediate outcomes after antiviral therapy and clinical outcomes … clinical outcomes. … transmission, extrahepatic outcomes, or harms). … improve clinical outcomes. … Preventive Services Task Force: linking intermediate outcomes and health outcomes in prevention.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/kGvn_HBPEEdfu2rs38VN8_
March 11, 2025 - , or health outcomes? … What are the effects of improvements in intermediate outcomes on health outcomes? … Outcomes: Study did
not report relevant outcomes. Quality: Study did not meet quality standards. … , or health outcomes? … What are the effects of improvements in intermediate
outcomes on health outcomes?
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/4NUuvS6nmzTdBgjBg3ELkE
January 01, 2020 - Limitation: Sparse reporting of patient health outcomes, longer-
term follow-up of outcomes, and harms … (question 1), intermedi-
ate cardiovascular disease–related outcomes (question 2),
behavioral outcomes … Pooled Effect Sizes for Intermediate Cardiovascular Health Outcomes, by Intervention Type
Outcomes, … for fasting
glucose and weight
outcomes; sparse
reporting of outcomes
beyond 24 mo;
limited number of … Trials reporting only behavi-
oral outcomes (no intermediate outcomes) found
small but significant improvement
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/chronic-kidney-disease-screening
July 13, 2023 - chronic kidney disease (CKD), * what are the effects of screening for CKD vs. no screening on clinical outcomes … adults with screen-detected CKD or CKD stages 1–3, † what are the effects of treatment on clinical outcomes … Progression to stage 5 CKD (end-stage renal disease, including renal replacement)
Composite renal outcomes … 3, 3a:
Sensitivity
Specificity
Area under the receiver operating characteristic curve
Outcomes … ; KDOQI=Kidney Disease Outcomes Quality Initiative.
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/healthy-lifestyle-and-physical-activity-for-cvd-prevention-adults-without-known-risk-factors-behavioral-counseling
June 04, 2020 - physical activity, and reduce sedentary behavior improve cardiovascular disease (CVD) and related health outcomes … What is the relationship between intermediate behavioral outcomes (i.e., diet and physical activity) … and health outcomes (i.e., cardiovascular morbidity and mortality, all-cause mortality, and quality of … levels, and fasting glucose levels) and health outcomes? … (e.g., functioning or well-being)
KQ 2: Intermediate outcomes
Blood pressure
Total, low-density
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/iron-deficiency-anemia-in-pregnant-women-screening-and-supplementation
August 20, 2024 - deficiency and iron deficiency anemia in pregnant persons to prevent adverse maternal and infant health outcomes … harms of routine iron supplementation in pregnant persons to prevent adverse maternal and infant health outcomes … iron deficiency with or without anemia during pregnancy to prevent adverse maternal and infant health outcomes … Evidence of intermediate outcomes in infants was limited to 2 trials 20 , 31 (n = 12,943) reporting … Micronutrient supplementation and pregnancy outcomes: double-blind randomized controlled trial in China
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/food-insecurity-screening
March 11, 2025 - Main Outcomes and Measures: Food insecurity; dietary, physiologic, quality of life, health outcomes; … , or health outcomes? … What are the effects of improvements in food security outcomes on intermediate and health outcomes? … What are the effects of improvements in intermediate outcomes on health outcomes? … Outcomes: Study did not report relevant outcomes. Quality: Study did not meet quality standards.
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/tobacco-cessation-adults-interventions
July 17, 2025 - Population-based smoking rates (i.e., not based on study sample but on underlying population)
Outcomes … KQ 1 (health outcomes):
All-cause mortality
Tobacco-related mortality
Tobacco-related morbidity … Dental/oral health
Quality of life
KQ 2 (behavioral outcomes): Tobacco cessation/tobacco … abstinence (continuous or point prevalence abstinence)
Cessation outcomes will be stratified by specific … We clarified that interventions and outcomes will be described by the specific tobacco or tobacco products
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www.uspreventiveservicestaskforce.org/uspstf/document/draft-research-plan/chronic-kidney-disease-screening
January 19, 2023 - chronic kidney disease (CKD), * what are the effects of screening for CKD vs. no screening on clinical outcomes … Among adults with CKD stages 1–3, † what are the effects of treatment on clinical outcomes? … Progression to stage 5 CKD (end-stage renal disease, including renal replacement)
Composite renal outcomes … 3, 3a:
Sensitivity
Specificity
Area under the receiver operating characteristic curve
Outcomes … ; KDOQI=Kidney Disease Outcomes Quality Initiative.
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www.uspreventiveservicestaskforce.org/uspstf/about-uspstf/methods-and-processes/procedure-manual/procedure-manual-appendix-viii-standardization-outcome-tables
July 01, 2017 - to Email
Print
Although it is not possible to completely standardize outcomes … of issues among preventive services, the following are some preferred entries for authors to use in outcomes … Rationale: preventive services with a large magnitude of effect should have substantial numbers of outcomes … Intermediate outcomes.
Number identified (with and without the condition).
Number treated. … Important health outcomes (e.g., strokes averted or cancers caused).
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www.uspreventiveservicestaskforce.org/uspstf/document/draft-research-plan/autism-spectrum-disorder-young-children-1
February 25, 2021 - Developmental, functional, and quality of life outcomes? … interventions targeting young children with ASD improve developmental, functional, and quality of life outcomes … initiation (by age and in relation to the establishment of an ASD diagnosis) associated with ASD-related outcomes … (i.e., developmental, functional, and quality of life outcomes)? … , family distress, false reassurance, and opportunity cost)
KQ 4: Developmental and functional outcomes
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan98/statin-use-in-adults-preventive-medication-november-2016
May 02, 2014 - Use of Statins to Improve Cardiovascular Outcomes
Text Description
Figure 2. … in adults ages 21 to 39 years on intermediate outcomes (e.g., lipid levels or atherosclerosis)? … Use of Statins to Improve Cardiovascular Outcomes
What is the comparative accuracy of different … Include
Exclude
Screening for Dyslipidemia to Improve Cardiovascular Outcomes … not listed as included
KQ 2: Adverse outcomes not associated with screening
KQ 3: Outcomes
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/obesity-in-children-and-adolescents-screening
June 30, 2022 - combined weight management interventions for children and adolescents with higher BMI affect weight outcomes … or cardiometabolic outcomes? … Health outcomes:
Cardiovascular or weight-related morbidity or mortality
Quality of life or … Most comments received by the USPSTF made suggestions regarding which outcomes should be included. … Based on public comments and key informant interviews, the USPSTF removed the outcomes of self-esteem
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/rLjXX_3oMKssbHxrj84UYA
Iron Deficiency Anemia and Iron Supplementation in Pregnant Women to Improve Maternal Health and Birth Outcomes … Iron Deficiency Anemia and Iron Supplementation in Pregnant Women to Improve Maternal Health and Birth Outcomes
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/hepatitis-c-screening
December 21, 2017 - What is the effectiveness of currently recommended antiviral treatments in improving health outcomes … What is the effect of antiviral treatments on behavioral outcomes? … , including intermediate outcomes
Setting
U.S. primary care, obstetrics/gynecology, emergency … Perinatal transmission of HCV infection
Other outcomes
Settings
U.S. labor and delivery … will be included for Contextual Question 3
Histologic outcomes, liver function tests
Setting
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/cognitive-impairment-in-older-adults-screening
October 19, 2017 - KQs 1, 4: Decisionmaking outcomes:
For patients and family/caregivers: Health care, legal, and … : (a priori defined as primary or secondary outcomes in the trial)
Health-related quality of life … ), and psychological harms (depression, anxiety)
KQs 1, 4:
Decisionmaking outcomes: Cost-related … outcomes
Patient-related outcomes: Cost-related outcomes; patient satisfaction (other than health-related … quality of life)
Societal outcomes: Cost-related outcomes
KQ 2: Cost-related outcomes
KQs 3,
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/8uE22djVfm8hF8wNg7wWYn
May 01, 2021 - screening and supplementation
for iron deficiency with and without anemia on maternal and infant health outcomes … deficiency and iron deficiency anemia
in asymptomatic pregnant persons on maternal and infant health outcomes … Evidence of intermediate outcomes in infants was limited to 2
trials20,31 (n = 12 943) reporting no … Clinically relevant poten-
tial outcomes included, but were not limited to, maternal health-
related … Micronutrient supplementation and
pregnancy outcomes: double-blind randomized
controlled trial in China
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www.uspreventiveservicestaskforce.org/uspstf/document/draft-research-plan/breast-cancer-medication-use-reduce-risk
December 28, 2023 - be described with respect to factors that can contribute to variability in intervention access and outcomes … medications to prevent primary breast cancer
Use of medications for treatment or prevention of other outcomes … mortality; all-cause mortality; and quality of life
KQ 2 (Harms): Adverse quality of life and health outcomes … Fractures
Ophthalmologic disorders
Genitourinary outcomes
Thromboembolic events
Cardiovascular … events
Risk of other cancers
Adverse outcomes related to quality of life
Noninvasive breast
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan31/iron-deficiency-anemia-in-pregnant-women-screening-and-supplementation-september-2015
July 15, 2013 - the benefits of routine iron supplementation on maternal and infant intermediate and clinical health outcomes … KQ 1: Maternal outcomes : Caesarian section rates, preterm delivery, postpartum depression; incidence … deficiency anemia; incidence of iron deficiency; hematologic indices and ferritin levels
Infant outcomes … KQs 1, 3: Maternal outcomes : Caesarian section rates, preterm delivery, postpartum depression … KQ 3: Maternal outcomes : Incidence of iron deficiency anemia; incidence of iron deficiency; hematologic