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  1. www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary23/diabetes-mellitus-type-2-in-adults-screening-2008
    June 15, 2008 - We identified 1 meta-analysis of antihypertensive trials that compared outcomes between persons with … Three studies reported cardiovascular outcomes with intensive lifestyle interventions in persons with … is unknown because studies were not powered for those outcomes or were not of sufficient duration. … [PMID: 15983291] Heart Outcomes Prevention Evaluation Study Investigators. … In a randomized trial, outcomes were not affected by intensive follow-up over 1 year.
  2. www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary47/speech-and-language-delay-in-preschool-children-screening-2006
    February 15, 2006 - Outcomes included speech and language measures and other functional and health outcomes such as social … Outcomes included speech and language measures as well as other functional and health outcomes as previously … Does Improvement in Speech and Language Outcomes Lead to Improved Additional Outcomes? … Does improvement in speech & language outcomes lead to improved additional outcomes? … Important outcomes considered.
  3. www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary44/sexually-transmitted-infections-behavioral-counseling-2008
    October 15, 2008 - of the evidence using biological outcomes. … KQ2 links to a lozenge labeled “Behavioral Outcomes.” … KQ3 proceeds downward to a lozenge labeled “Other Positive Outcomes.” … Self-reported measures of STI outcomes should be interpreted cautiously. … Self-reported measures of STI outcomes should be interpreted cautiously.
  4. www.uspreventiveservicestaskforce.org/home/getfilebytoken/Bd9Cgr5WNueNbmfsPxUKDP
    September 01, 2012 - Weight-loss outcomes improved when interventions involved more sessions (12 to 26 sessions in the first … Less is known about the long-term health outcomes of overweight than of obesity. … These studies assess the effects of the preventive service on health outcomes. … Low The available evidence is insufficient to assess effects on health outcomes. … More information may allow an estimation of effects on health outcomes.
  5. www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-review49/hepatitis-c-screening-2013
    November 15, 2012 - Data Synthesis:  No study evaluated clinical outcomes associated with screening compared with no screening … The analytic framework focuses on direct evidence that HCV screening improves important health outcomes … Clinical outcomes were mortality, end-stage liver disease, cirrhosis, hepatocellular carcinoma, need … No study compared clinical outcomes between individuals screened and not screened for HCV infection or … Indications, methods, and outcomes of percutaneous liver biopsy in England and Wales: an audit by the
  6. www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan-aspirin-to-prevent-cancer/aspirin-to-prevent-cardiovascular-disease-and-cancer-april-2016
    October 07, 2013 - The figure illustrates how aspirin chemoprevention may influence mortality outcomes (KQ 1) in adults … The figure also depicts how this intervention may affect intermediate outcomes, including cancer incidence … KQs 1, 2 (health and cancer outcomes): Incidence of cancer Cancer-related mortality All-cause … mortality KQs 3–5 (colorectal cancer outcomes): Colorectal cancer incidence Colorectal cancer … The most significant change is expansion of the scope of outcomes evaluated from colorectal cancer to
  7. www.uspreventiveservicestaskforce.org/home/getfilebytoken/4zmYnqJXLv8g4LzLrrDDrm
    December 01, 2014 - Maternal Outcomes The USPSTF found evidence of a 24% reduction in risk for preeclampsia (pooled RR, … The USPSTF found limited evidence on long-term outcomes in offspring from in utero exposure to low-dose … These studies assess the effects of the preventive service on health outcomes. … Low The available evidence is insufficient to assess effects on health outcomes. … More information may allow an estimation of effects on health outcomes.
  8. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary-dyslipidemia/statin-use-in-adults-preventive-medication
    November 13, 2016 - versus no screening, treatment versus no treatment, or delayed versus earlier treatment on clinical outcomes … studies on the benefits or harms of screening versus no screening for dyslipidemia on cardiovascular outcomes … identified no studies on benefits or harms of treatment versus no treatment regarding cardiovascular outcomes … evaluated the effects of screening versus no screening or treatment versus no treatment on clinical outcomes … , we also found no evidence regarding the effects of drug treatment of dyslipidemia on intermediate outcomes
  9. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary-dyslipidemia/statin-use-in-adults-preventive-medication-november-2016
    November 13, 2016 - versus no screening, treatment versus no treatment, or delayed versus earlier treatment on clinical outcomes … studies on the benefits or harms of screening versus no screening for dyslipidemia on cardiovascular outcomes … identified no studies on benefits or harms of treatment versus no treatment regarding cardiovascular outcomes … evaluated the effects of screening versus no screening or treatment versus no treatment on clinical outcomes … , we also found no evidence regarding the effects of drug treatment of dyslipidemia on intermediate outcomes
  10. www.uspreventiveservicestaskforce.org/home/getfilebytoken/JvkFnVVvWLoFBB9xR9wwVK
    May 01, 2015 - No clinical trial data support a treatment threshold to improve clinical outcomes. … of any known intermediate outcomes. … These studies assess the effects of the preventive service on health outcomes. … Low The available evidence is insufficient to assess effects on health outcomes. … More information may allow an estimation of effects on health outcomes.
  11. www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/abdominal-aortic-aneurysm-screening-february-2005
    February 15, 2005 - Formulas for Calculations in Outcomes Table 2* Expand … ascertainment, and duration of followup. 31 We used graphs of trial outcomes and the Mantel-Haenszel … While the Chichester trial also reported outcomes for 10 years of followup 5 , we did not include these … Long-term outcomes of immediate repair compared with surveillance of small abdominal aortic aneurysms … Effect of antihypertensive drug treatment on cardiovascular outcomes in women and men.
  12. www.uspreventiveservicestaskforce.org/home/getfilebytoken/HQGXw2wkcM7q6TA5eWzdT5
    January 01, 2010 - Other Positive Outcomes Harms STI (Biological) Outcomes KQ4 KQ3 KQ1 KQ � key question. … colleagues (20), used self- reported outcomes and a shorter duration of follow-up. … Measures of self-reported behavioral outcomes (for ex- ample, unprotected sexual intercourse, condom … Self-reported measures of STI outcomes should be interpreted cautiously. … Self-reported measures of STI outcomes should be interpreted cautiously.
  13. www.uspreventiveservicestaskforce.org/uspstf/recommendation/genital-herpes-screening-2005
    March 15, 2005 - the safety of antiviral therapy in pregnant women and neonates Antiviral therapy improves health outcomes … There is good evidence that antiviral therapy improves health outcomes in symptomatic persons (e.g., … The USPSTF found good evidence that [the service] improves important health outcomes and concludes that … The USPSTF found at least fair evidence that [the service] can improve health outcomes but concludes … Poor: Evidence is insufficient to assess the effects on health outcomes because of limited number or
  14. www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan-nonpregnant-adolescents-and-adults/human-immunodeficiency-virus-hiv-infection-screening
    June 15, 2017 - treatment include adverse effects associated with antiretroviral therapy, including cardiometabolic outcomes … standard HIV testing KQs 4, 5: Currently recommended antiretroviral therapy regimens   Outcomes … results, anxiety and effects of labeling, and partner discord, abuse, or violence KQ 5: Adverse outcomes … associated with antiretroviral therapy, including cardiometabolic outcomes   Comparisons KQs
  15. www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/cardiovascular-disease-screening-using-nontraditional-risk-assessment
    September 03, 2015 - The figure illustrates how nontraditional risk factor assessment may result in improved health outcomes … reclassification (KQ2) and how treatment based on nontraditional risk factor assessment may improve health outcomes … Does detection of incidental findings improve patient outcomes? … disease risk assessment) KQs 4, 5: No treatment or usual care (as defined by the study) Outcomes
  16. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary27/breast-cancer-medications-for-risk-reduction-2013
    April 15, 2013 - Health outcomes include signs, symptoms, conditions, or events as opposed to intermediate outcomes, such … , timing of outcomes measurement, and setting (PICOTS) format 14 . … on breast cancer outcomes regardless of age and family history of breast cancer 22 . … How do outcomes vary by population subgroups? 4. … * For invasive breast cancer, other outcomes are specifically indicated.
  17. www.uspreventiveservicestaskforce.org/uspstf/first-annual-report-congress-high-priority-evidence-gaps-clinical-preventive-services-v
    December 01, 2011 - Whereas the ability of primary care-based interventions to lead directly to changes in health outcomes … (including long-term outcomes) in a standardized fashion are needed. … outcomes are also needed.   … Additional research should also examine the long-term outcomes and effects of interventions delivered … Observational studies of risks for longer-term outcomes associated with the use of antidepressants would
  18. www.uspreventiveservicestaskforce.org/home/getfilebytoken/za7BqXMwT8BMz4Z_ygrvKm
    May 01, 2004 - The USPSTF found good evidence that [the service] improves important health outcomes and concludes that … The USPSTF found at least fair evidence that [the service] can improve health outcomes but concludes … Fair: Evidence is sufficient to determine effects on health outcomes, but the strength of the evidence … Poor: Evidence is insufficient to assess the effects on health outcomes because of limited number or … Teutsch, MD, MPH (Executive Director, Outcomes Research and Management, Merck & Company, Inc., West Point
  19. www.uspreventiveservicestaskforce.org/uspstf/sites/default/files/inline-files/uspstfchildhealth.pdf
    October 01, 2016 - in the evidence gaps and the future research necessary to advance the field and improve child health outcomes … Clinical preventive services can improve health outcomes during childhood and adolescence and have a … , the relationship between intermediate or proxy outcomes and long- term health outcomes, and harms associated … important to recognize that when evaluating the net benefit of screening, the focus is on long-term outcomes … However, most treatment studies focus on outcomes frommore–severely affected children than those expected
  20. www.uspreventiveservicestaskforce.org/uspstf/sites/default/files/file/supporting_documents/sleepapneadraftrsbulletin.pdf
    July 11, 2016 - calling for more research about whether screening for obstructive sleep apnea leads to improved health outcomes … determine whether screening for OSA in adults without recognized symptoms leads to improved health outcomes … more research on whether screening in adults without known symptoms leads to improvements in health outcomes … He is co- director of the Virginia Ambulatory Care Outcomes Research Network and director of community

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