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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/perinatal-depression-interventions-to-prevent
June 01, 2023 - limited to no more than 15 minutes of information)
Placebo required for medication trials
Outcomes … KQ 1:
Maternal health outcomes:
Depression incidence or symptoms (required)
Suicide deaths … including psychiatric hospital admissions
Marital discord and family function
Infant/child health outcomes … due to adverse events in trials of treatment benefit
KQ 1: Maternal behavioral intermediate outcomes … comment, the Research Plan was revised to clarify the list of included and excluded maternal health outcomes
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/healthy-diet-and-physical-activity-counseling-adults-with-high-risk-of-cvd
September 13, 2018 - What is the relationship between behavioral outcomes (e.g., diet and physical activity) and health outcomes … What is the relationship between intermediate outcomes (e.g., blood pressure, lipid levels, blood glucose … , and body mass index) and health outcomes? … (e.g., functioning or well-being)
KQ 2: Intermediate outcomes
Blood pressure
Total, low-density … Dietary intake or patterns
Physical activity
Sedentary behavior
KQ 4: Adverse outcomes
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/827CwGYMVawpVoVg_syJpF
October 01, 2015 - Iron Deficiency Anemia and Iron Supplementation in
Pregnant Women to Improve Maternal Health and Birth Outcomes … Several studies reported inconsistent findings on these
health outcomes. … These studies assess the effects of the preventive service on health
outcomes. … Low The available evidence is insufficient to assess effects on health outcomes. … More information may allow an estimation of effects on health outcomes.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/SJbAXUAQTv2GWemMuBab6W
April 08, 2025 - MAIN OUTCOMES AND MEASURES Child and maternal health outcomes, prevalence, and
duration of any and exclusive … Benefits on Health Outcomes
Key Question 1. … Benefits on Breastfeeding Outcomes
Key Question 2. … :
Study did not report relevant
outcomes. … 19 RCTs (n = 11 175) Good: 5
Fair: 14
Infant health outcomes variably
reported
Most outcomes based on
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/child-maltreatment-primary-care-interventions-november-2018
November 27, 2018 - Several trials presented outcomes at multiple periods. … Results were not statistically significant for 7 outcomes. … Other Developmental Outcomes. … Furthermore, interpretation of some outcomes can be challenging. … outcomes (such as interpregnancy interval).
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www.uspreventiveservicestaskforce.org/uspstf/about-uspstf/methods-and-processes/procedure-manual/procedure-manual-appendix-xiii-template-scoping-decision-problem-address-through-decision-modeling
July 01, 2017 - Health outcomes: Deaths, quality-adjusted life years, disability-adjusted life years, incident disease … Intermediate outcomes: Intermediate disease or process outcomes necessary for validation or to determine … disease spectrum, analysis perspective, target population, alternative interventions, health and other outcomes … Population
Interventions/strategies
Comparators/strategies
Health outcomes …
Intermediate outcomes
Time horizon
Model perspective
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/sCkggReHbVWXtLoqWhEPrh
July 01, 2023 - screening for or treatment of IDA on growth or child cognitive,
psychomotor, or neurodevelopmental outcomes … for or treatment of IDA; and
• The short- and long-term effects of change in iron status on health outcomes … Outcomes at one year include
cognitive and functioning measures and serum ferritin and hemoglobin levels … Iron deficiency in infancy and neurocognitive and educational
outcomes in young adulthood.
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan44/depression-in-adults-screening
July 03, 2014 - results to providers (with or without additional care management supports) result in improved health outcomes … Does treatment (psychotherapy, antidepressants, or collaborative care) result in improved health outcomes … Benefits of screening (KQ 1):
Primary health outcomes
Depression symptoms … Depression remission
Other health outcomes
Depression response
Suicide deaths … symptoms
Depression remission
Other health outcomes
Depression response
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary-screening-for-familial-hypercholesterolemia/lipid-disorders-in-children-screening-july-2016
August 09, 2016 - for screening studies, intermediate outcomes and health outcomes, and harms. … No relevant studies were found on adult health outcomes, intermediate outcomes, or harms of FH screening … and Adult Health Outcomes
Key Question 8. … Outcomes key question
What is the association between intermediate outcomes in childhood and adolescence … outcomes and adult health outcomes
0
0
No evidence on the association between intermediate outcomes
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/intimate-partner-violence-and-abuse-of-elderly-and-vulnerable-adults-screening
June 24, 2025 - Main Outcomes and Measures: Test accuracy; abuse exposure and associated morbidity, quality of life, … Results for other outcomes were mixed. … effect for these outcomes ( Figure 6 ; eTable 7 in the Supplement). … The questions are depicted by linkages that relate interventions and outcomes. … For other outcomes, including anxiety, PTSD, and birth outcomes, SOE is insufficient due to unknown consistency
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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/hepatitis-c-screening
March 02, 2020 - Main Outcomes and Measures: Mortality, morbidity, quality of life, screening and treatment harms, and … SVR and Health Outcomes
Key Question 9. … Direct evidence on the effects of antiviral therapy on clinical outcomes is limited. … link between SVR and clinical outcomes with current DAA therapies. … The questions are depicted by linkages that relate interventions and outcomes.
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan142/obstructive-sleep-apnea-in-adults-screening-january-2017
October 30, 2014 - For adults with OSA, treatment may improve intermediate outcomes, such as changes in the apnea-hypopnea … index, blood pressure, and daytime somnolence/sleepiness (key question 4), and also health outcomes, … Does screening for obstructive sleep apnea (OSA) in adults improve health outcomes?
1b. … Is there an association between AHI and health outcomes?
7a. … Is there an association between reduction in blood pressure and health outcomes?
5.
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/iron-deficiency-anemia-in-pregnant-women-screening-and-supplementation-september-2015
September 07, 2015 - harms of routine iron supplementation for pregnant women to prevent adverse maternal health and birth outcomes … screening for iron deficiency anemia in pregnant women to prevent adverse maternal health and birth outcomes … Several studies reported inconsistent findings on these health outcomes. … Older observational studies suggest an association between adverse outcomes in infants and anemia in … Supplement doses ranged from 20 to 120 mg per day, and outcomes were measured at various time points,
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www.uspreventiveservicestaskforce.org/uspstf/document/RecommendationStatementFinal/child-maltreatment-primary-care-interventions
March 19, 2024 - , included clinical professionals (eg, nurses), and compared interventions with usual care. 1 , 21 Outcomes … ) or hospital, and failure to provide for the child’s medical needs. 1 , 21 Interpretation of some outcomes … with the control group (adjusted odds ratio, 1.85 [95% CI, 1.02-2.85]). 1 , 21 , 25
Intermediate Outcomes … reported some benefit in study-specific outcomes; however, study construction and outcomes varied substantially … Evidence of benefit on child maltreatment outcomes is limited and inconsistent.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/AoSMttkvyssBywB_Uo-omz
November 01, 2004 - intervention with Rh (D) immunoglobulin, as
appropriate, prevents maternal sensitization and
improves outcomes … The USPSTF
found good evidence that [the service] improves important health outcomes and concludes that … The USPSTF
found at least fair evidence that [the service] can improve health outcomes but concludes … Fair: Evidence is sufficient to determine effects on health outcomes, but the strength of the evidence … Poor: Evidence is insufficient to assess the effects on health outcomes because of limited number or
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/drug-use-illicit-primary-care-interventions-for-children-and-adolescents
August 30, 2018 - referable interventions to prevent drug use in children, adolescents, and young adults improve health outcomes … or other related outcomes? … referable interventions to prevent drug use in children, adolescents, and young adults improve drug use outcomes … KQ 1 (H ealth, social, educational, and other outcomes):
Health outcomes:
All-cause mortality … KQ 2 (Behavioral outcomes):
Drug use ( required ) (self-reported and/or biologic measures):
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www.uspreventiveservicestaskforce.org/uspstf/document/draft-research-plan/human-immunodeficiency-virus-hiv-infection-pregnant-nonpregnant-adults
November 30, 2023 - treatment include adverse effects associated with antiretroviral therapy, including cardiometabolic outcomes … , and partner discord, abuse, or violence. † Harms of treatment include adverse maternal and infant outcomes … DOR/TDF/3TC †
DOR/TAF/FTC †
EFV/TAF or TDF/FTC or 3TC †
RPV/TAF or TDF/FTC †
Outcomes … associated with currently recommended antiretroviral therapy regimens, including cardiometabolic outcomes … harms following in utero exposure to currently recommended ART regimens
KQs 1–3: Pharmacokinetic outcomes
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www.uspreventiveservicestaskforce.org/uspstf/behavioral-counseling-interventions-evidence-based-approach-figure-2
November 01, 2013 - The figure "reads" from left to right and connects a series of boxes (containing population groups or outcomes … question(s) are to be answered to understand each action or association between population groups and outcomes … Below this line are two ovals labeled "Adverse Effects" and another box labeled "Other Positive Outcomes … The intervention arrow is connected by a solid arrow to the "Other Positive Outcomes" box below (key … The follow-up intervention arrow also points to the "Other Positive Outcomes" box (key question 10) and
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/prevention-of-human-immunodeficiency-virus-hiv-infection-pre-exposure-prophylaxis-june-2019
July 26, 2017 - analytic framework depicts the relationship between the population, risk assessment, intervention, outcomes … PrEP, including other STIs, renal dysfunction, adverse effects on bone, effects on pregnancy-related outcomes … * Harms also include renal dysfunction, adverse effects on bone, pregnancy-related outcomes, infection … Comparisons
Placebo or no PrEP (including deferred PrEP)
One PrEP regimen vs. another
Outcomes … , and adherence to PrEP regimen †
Outcomes not listed, including condom use
Setting
All KQs
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary23/iron-deficiency-anemia-in-young-children-screening
March 30, 2015 - Five of 6 trials sparsely reporting various growth outcomes found no clear benefit of supplementation … However, these studies had methodologic flaws; 4 for example, the outcomes examined were varied and … outcomes; and diagnosis of developmental delay), mortality, and quality of life. … Although not clearly clinical outcomes, developmental test scores after follow-up periods of 3 to 12 … were included for developmental test score outcomes, and 10 trials were included for hematological outcomes