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  1. www.uspreventiveservicestaskforce.org/home/getfilebytoken/2VxcSta8ko2L_GC97XjZqm
    September 01, 2015 - Iron Deficiency Anemia and Iron Supplementation in Pregnant Women to Improve Maternal Health and Birth Outcomes … Deficiency Anemia and Iron Supplementation in Pregnant Women to Improve Maternal Health and Birth Outcomes … Deficiency Anemia and Iron Supplementation in Pregnant Women to Improve Maternal Health and Birth Outcomes … Deficiency Anemia and Iron Supplementation in Pregnant Women to Improve Maternal Health and Birth Outcomes … adverse maternal health and birth outcomes Negative events, such as premature birth, low birth weight
  2. www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/iron-deficiency-anemia-in-pregnant-women-screening-and-supplementation
    July 07, 2022 - KQ 1: Maternal health outcomes: Mortality; health-related quality of life; preeclampsia (severe … KQ 2: Short- or long-term outcomes   Study Designs KQ 1: Randomized, controlled trials … KQs 1, 3, 5: Maternal health outcomes: Mortality; health-related quality of life; preeclampsia ( … : Cesarean delivery rates Infant intermediate outcomes: Hematologic indices and ferritin levels; low … Commenters also suggested considering health outcomes for children older than age 1 year.
  3. www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/cognitive-impairment-older-adults
    June 12, 2025 - : (a priori defined as primary or secondary outcomes in the trial) Health-related quality of life … outcomes KQ 2: Sensitivity, specificity, or contingency table data allowing for calculation of … : Cost-related outcomes Patient-related outcomes: Cost-related outcomes; patient satisfaction ( … quality of life) Societal outcomes: Cost-related outcomes KQs 3, 5: Patient or family/caregiver … Further, we removed the minimum followup requirement for advanced planning outcomes.
  4. www.uspreventiveservicestaskforce.org/uspstf/document/draft-research-plan/cognitive-impairment-older-adults
    March 06, 2025 - : (a priori defined as primary or secondary outcomes in the trial) Health-related quality of life … Global stress/distress Caregiver burden Depression Anxiety Societal outcomes : Safety … outcomes KQ 2: Sensitivity, specificity, or contingency table data allowing for calculation of … : Cost-related outcomes Patient-related outcomes: Cost-related outcomes; patient satisfaction ( … quality of life) Societal outcomes: Cost-related outcomes KQs 3, 5: Patient or family/caregiver
  5. www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/food-insecurity-screening
    July 28, 2022 - , or health outcomes? … What are the effects of improvements in food security outcomes on intermediate and health outcomes? … What are the effects of improvements in intermediate outcomes on health outcomes? … KQs 1, 4: Food and nutrition security outcomes Access to food Behavioral outcomes (e.g., dietary … outcomes (e.g., number of food pantries) Cost outcomes KQ 2: Test positivity or test yield only
  6. www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/cardiovascular-disease-enhanced-risk-assessment-non-traditional-risk-factors
    September 26, 2024 - cardiovascular disease risk assessment with coronary artery calcium scoring on cardiovascular health outcomes … enhanced cardiovascular disease risk assessment with coronary artery calcium scoring on physiologic outcomes … , behavioral outcomes, or patient and provider decision-making outcomes? … Does treatment guided by coronary artery calcium scoring lead to improved health outcomes? … (e.g., lipid levels, blood pressure), behavioral outcomes (e.g., smoking cessation, physical activity
  7. www.uspreventiveservicestaskforce.org/uspstf/about-uspstf/methods-and-processes/procedure-manual/procedure-manual-section-3-topic-work-plan-development
    June 22, 2025 - Outcomes are depicted using a rectangle; intermediate outcomes have rounded corners and health outcomesOutcomes Versus Health Outcomes Analytic frameworks used by the Task Force distinguish between intermediate … outcomes and health outcomes, and consider both beneficial and harmful outcomes (e.g., adverse effects … Health outcomes Health outcomes are symptoms, functional levels, and conditions that patients can feel … Intermediate outcomes Intermediate outcomes are outcomes that may be influenced by a preventive service
  8. www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/lipid-disorders-in-children-screening
    August 19, 2021 - (e.g., cardiovascular disease [CVD] events * or mortality) or improve intermediate outcomes (e.g., … What is the association between lipid-related childhood and adolescent intermediate outcomes and adult … health outcomes? … to the family, and the inclusion of adult health outcomes in the Analytic Framework. … Adult health outcomes were retained in the Analytic Framework in accordance with USPSTF methods.
  9. www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/behavioral-counseling-interventions-promote-healthy-diet-physical-activity-weight-loss-prevent-cardiovascular-disease-adults
    November 02, 2023 - diet, physical activity, and/or weight loss improve cardiovascular disease (CVD) and related health outcomes … What is the relationship between changes in intermediate outcomes and health outcomes? … What is the relationship between changes in behavioral outcomes and health outcomes? … KQ 1: Health outcomes: All-cause and CVD mortality CVD events Quality of life, well-being … Association between change in behavioral and health outcomes KQ 5: Harms: Harms occurring
  10. www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/hepatitis-b-virus-infection-screening
    March 14, 2019 - To the right of antiviral medications, one arrow leads to intermediate outcomes of virologic improvement … as a result of antiviral treatment and reduction in risk of HBV-related adverse health outcomes (Key … symbolizes Key Question 1 about the direct benefits of screening on clinical health outcomes. … How effective is antiviral treatment in improving intermediate outcomes among nonpregnant adolescents … of chronic HBV infection and reduction in risk of HBV-related adverse health outcomes?
  11. www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/gestational-diabetes-screening
    June 06, 2019 - Does screening for gestational diabetes mellitus (GDM) reduce poor health outcomes?     b. … Does screening for GDM reduce poor intermediate outcomes?     c. … Does treatment of GDM during pregnancy reduce poor health outcomes?     b. … Does treatment of GDM during pregnancy reduce poor intermediate outcomes?     c. … Based on the comments it received, the USPSTF recategorized some intermediate outcomes as health outcomes
  12. www.uspreventiveservicestaskforce.org/home/getfilebytoken/aRJ-3-AWuVvmC_kmoGCVHp
    , additional evidence would be needed to link intermediate outcomes to health outcomes Relevant … / Timing Setting Maternal intermediate outcomes: Examples include incidence of iron deficiency … outcomes link (observational studies, including those embedded within clinical trials). … , additional evidence would be needed to link intermediate outcomes to health outcomes Maternal … , additional evidence would be needed to link intermediate outcomes to health outcomes Relevant
  13. www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/tobacco-use-intervention-prevention-cessation-children-adolescents
    June 27, 2024 - tobacco * or increase tobacco cessation rates in children and adolescents improve health and related outcomes … , cardiovascular outcomes, mental health, substance use disorder diagnosis) Children and adolescents … only: School-based outcomes (e.g., attendance, grades) Social and legal outcomes (e.g., citations … and behavioral outcomes. … were expanded to include social, legal, and educational outcomes, as well as quality of life.
  14. www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/obesity-in-children-and-adolescents-screening
    June 18, 2024 - Main Outcomes and Measures: BMI and other weight-related outcomes, cardiometabolic measures, quality … Relevant outcomes included health outcomes (mortality, quality of life, functioning, depression, medical … or cardiometabolic outcomes? … Benefits of Interventions: Behavioral Outcomes KQ3. … : Study did not report relevant outcomes.
  15. www.uspreventiveservicestaskforce.org/uspstf/document/draft-research-plan/cardiovascular-disease-enhanced-risk-assessment-non-traditional-risk-factors
    April 25, 2024 - assessment with coronary artery calcium scoring or the ankle brachial index on cardiovascular health outcomes … disease risk assessment with coronary artery calcium scoring or the ankle brachial index on physiologic outcomes … or patient and provider decision-making outcomes? … For risk prediction studies, we will abstract model performance outcomes by race and ethnicity and compare … will be captured: Physiologic outcomes (e.g., lipid levels, blood pressure) Decision-making outcomes
  16. www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/child-maltreatment-primary-care-interventions
    May 19, 2022 - Do primary care–feasible or referable preventive interventions that report on child maltreatment outcomes … examine the association between social determinants of health and child maltreatment outcomes? … listed in KQ 1 KQ 1: Outcomes not otherwise specified, studies without direct or proxy measures … *These outcomes will be evaluated in studies that also report at least one child maltreatment outcome … Reviewers suggested including social determinants of health as outcomes.
  17. www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/child-maltreatment-primary-care-interventions
    March 19, 2024 - The evidence was inconclusive for all other outcomes because of the limited number of trials on each … A subset of trials reported outcomes at 1 or more time points after the first analysis of results. … Trials measuring outcomes for later time points (with follow-up ranging from 3 to 15 years) provided … Thirteen RCTs reported on hospitalization outcomes (eTables 24-27 in the  JAMA  Supplement). 14 , 16 … Additionally, interpretation of some outcomes could be challenging.
  18. www.uspreventiveservicestaskforce.org/home/getfilebytoken/d8DVjQhw6JgjWaBtED97s6
    functioning outcomes; improvement in depressive symptoms) KQ2: Cardiometabolic outcomes, improvement … functioning outcomes; improvement in depressive symptoms) KQ2: Cardiometabolic outcomes, improvement … outcomes, improvement in weight/BMI KQ3: Improvement in dietary patterns, increased physical … functioning outcomes; improvement in depressive symptoms) KQ2: Cardiometabolic outcomes, maintenance … : KQ1: Psychosocial outcomes (e.g., quality of life outcomes, especially weight-related quality of
  19. www.uspreventiveservicestaskforce.org/home/getfilebytoken/e9f8a_uGMXxSbBUxpRPkrc
    June 18, 2024 - MAIN OUTCOMES AND MEASURES BMI and other weight-related outcomes, cardiometabolic measures, quality of … Relevant outcomes included health outcomes (mortality, quality of life, functioning, depression, medical … or cardiometabolic outcomes? … or cardiometa- bolic outcomes? … : Study did not report relevant outcomes.
  20. www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/iron-deficiency-anemia-in-pregnant-women-screening-and-supplementation
    August 20, 2024 - Main Outcomes and Measures: Maternal and infant clinical outcomes, hematologic indices, and harms. … Eligible maternal outcomes were health outcomes (eg, mortality, quality of life, preeclampsia, postpartum … Infant outcomes were health outcomes (eg, perinatal mortality, respiratory distress, neonatal intensive … Timing of maternal outcomes was classified as during pregnancy, at term, and postpartum; infant outcomes … Findings were similar for third trimester outcomes.

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