-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-grading-strength_methods.pdf
July 01, 2009 - bodies of evidence are needed to link the intervention to
health outcomes. … Thus, strength of
evidence should relate to those important outcomes. … instead
of health outcomes. … Directness may be contingent on the outcomes of
interest. … rather
than health outcomes and use of indirect
comparisons.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/prostate-cancer-therapies-update_research-protocol.pdf
April 01, 2013 - • No RCT reported head-to-head comparisons of treatment outcomes stratified by
race/ethnicity. … the majority reporting biochemical progression or
recurrence as the primary outcomes. … potential for disease progression) affect the outcomes of these therapies overall and
differentially … case volume and outcomes
Studies using administrative data that measured outcomes in
different locations … Outcomes
• The primary outcome is overall mortality or survival.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/case-management-future_research.pdf
June 01, 2015 - Director, EPC Program Task Order Officer
Center for Outcomes and Evidence Center for Outcomes … Patient-centered outcomes, including mortality, quality of life, disease-specific health
outcomes, … Patient-centered outcomes, including mortality, quality of life, disease-specific health
outcomes, … D.3 Link components and
outcomes
Mayo, 20119 To determine
impact of CM on
any patient
outcomes, … allowing
diversity of
outcomes across
patients.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/prostate-cancer-antigen-3-gene_research.pdf
April 01, 2013 - Does the addition of PCA3 testing
change long-term health outcomes
in prostate screening? … Does addition of PCA3 testing
change long-term health
outcomes in prostate screening? … The strength of evidence for these outcomes was insufficient. … The
strength of evidence for all comparators and outcomes was insufficient. … Uncertainty of impact of PCA3 in biopsy decisionmaking on long term health outcomes.
7.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/progestogens-preterm-birth_executive.pdf
September 01, 2012 - • Longer term outcomes (e.g., neurodevelopmental
delay and future reproductive outcomes)?
KQ2. … • Longer term outcomes?
KQ3. … information on modifiers of treatment outcomes. … Mean gestational age at
birth and other outcomes did not differ. … Committee
on Understanding Premature Birth and Assuring Healthy
Outcomes.
-
effectivehealthcare.ahrq.gov/sites/default/files/study-objectives-and-questions-chapter-1.pptx
January 01, 2013 - and investigators are willing to accept a priori
Describe the meaningful magnitude of change in the outcomes … investigators are willing to accept a priori; and describe the meaningful magnitude of change in the outcomes … Outcomes: What are the outcomes of interest? … Timing: What is the time frame of interest for assessing outcomes? … Are decisionmakers interested in short-term or long-term outcomes?
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/ankyloglossia_research-protocol.pdf
June 30, 2014 - ,
breastfeeding mechanics and related outcomes typically improved. … This review did not
evaluate non-surgical management or broader outcomes. … Key Question 1 is focused on breastfeeding
outcomes in infants treated for ankyloglossia. … Deciding which outcomes are to be extracted. … Grading the Strength of Evidence (SOE) for Major Comparisons and Outcomes.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/type-2-diabetes-medications-2007_executive.pdf
January 01, 2007 - Many outcomes besides HbA1c and lipid levels are
important when evaluating and comparing oral diabetes … Microvascular outcomes. … (such as time to dialysis) as
well as short-term proteinuria outcomes. … Rosiglitazone evaluated for cardiovascular
outcomes–an interim analysis. N Engl J Med 2007. … Synopsis of comparative effectiveness of oral diabetes medications
Outcomes SU vs. Met SU vs.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/grading.ppt
January 01, 2010 - bodies of evidence are needed to link the intervention to health outcomes. … Intermediate or surrogate outcomes instead of health or patient-centered outcomes
Example: laboratory … /proxy outcomes
Better strength of evidence
Indirect (e.g., A vs. … Thus, strength of evidence should relate to those important outcomes. … For some treatments, data may be lacking about one or more of the outcomes.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-grading-evidence_methods.pdf
November 01, 2013 - The Patient-
Centered Outcomes Research Institute (PCORI) has defined patient-centered outcomes as those … and intermediate outcomes. … or reporting of unplanned outcomes … OIS concerns the minimum number of
patients (for continuous outcomes) and events (for dichotomous outcomes … Outcomes
Research.
-
effectivehealthcare.ahrq.gov/sites/default/files/mcda-johnson.pdf
August 27, 2012 - Social Science and Medicine, 1995
Slide 4
Types of Self-Reported Data
Patient-
Reported
Outcomes … Health-State
Utilities
Stated
Preferences
Patient-
Reported
Outcomes
Health-State
Utilities … Duration
PREFERENCE UTILITY
Clinical Outcomes
Duration
Treatment factors
– Side … Poster presented at the International
Society for Pharmacoeconomics and Outcomes Research 16th Annual … Poster presented at the International
Society for Pharmacoeconomics and Outcomes Research 16th Annual
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/registries-guide_executive.pdf
April 01, 2007 - Layout 1
User’s Guide to
Registries Evaluating
Patient Outcomes:
Summary
Advancing Excellence in … Registries for Evaluating Patient Outcomes: A User’s Guide. … • Operational definitions of outcomes are clearly defined. … • The followup period is reasonably sufficient to capture the main outcomes of interest. … • The followup period is sufficient to capture outcomes of interest.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/renal-artery-stenosis_research-2007.pdf
January 01, 2007 - This framework addressed relevant clinical
outcomes. … It also examined clinical predictors that affected treatment outcomes. … Cardiovascular outcomes
Only Webster 1998 (SNRASCG) reported on cardiovascular outcomes.12 The study … Two studies reported blood pressure outcomes. … to whether any pre-
intervention factors may predict clinical outcomes.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/bundled-payments-quality-effects_research-protocol.pdf
June 23, 2011 - Study Outcomes. … Study Outcomes. Same as for KQ 1.
Timing. Same as for KQ 1.
Settings. … Evidence is indirect if:
• It uses intermediate or surrogate outcomes instead of
health outcomes … Directness may be contingent on the outcomes of interest. … rather
than health outcomes and use of indirect
comparisons.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/opioid-treatments-chronic-pain-protocol.pdf
December 19, 2018 - Details regarding the populations, interventions, comparators,
and outcomes are shown in Table 1. … We will apply similar methodology to other outcomes measures. … (e.g., use of unvalidated or nonstandardized outcomes,
measurement of short-term or surrogate outcomes … Annual Surveillance Report of Drug-Related
Risks and Outcomes — United States, 2017. … Annual surveillance report of drug-related risks
and outcomes — United States, 2018.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/transparency-tympanostomy_research-protocol.pdf
September 02, 2016 - , quality of life and patient-centered outcomes, and intermediate outcomes? … , quality of life and patient-
centered outcomes, and intermediate outcomes? … • KQ 1, 2: Indications for tympanostomy tubes
o Hearing and vestibular outcomes
1. … Speech and language outcomes
3. Educational achievement
4. … Behavioral outcomes such as disobedience, enuresis, or
tantrums
o Intermediate outcomes
1.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/transparency-infertility_research-protocol.pdf
September 02, 2016 - detecting publication bias (e.g., funnel plots, Beggs rank correlation) are
underpowered.3 Comparing outcomes … KQ 6: What are the short- and long-term health outcomes of donors in infertility?
a. … Do short- and long-term outcomes differ among different induction/retrieval
protocols? … • Outcomes: (Note that these outcomes are ordered in approximate relative importance to
patients, … • Outcomes (men):
o Quality-of-life outcomes
• Timing :
o Short term:
§ From time of beginning
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/atypical-antipsychotics-off-label-update_research-protocol.pdf
May 19, 2010 - Outcomes: For efficacy, we will report commonly used objective outcomes such as symptom
scores, response … Outcomes are listed in appendix A. … Outcomes are listed in appendix A. … outcomes are the same as in KQ1 and KQ2. … For efficacy/effectiveness outcomes, a statistician will extract data.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/prostate-cancer_executive.pdf
February 01, 2008 - How do patient characteristics
affect outcomes? … How do provider and hospital
characteristics affect outcomes? … How do tumor characteristics
affect outcomes? … No effectiveness
different regimens outcomes reported. … How do
tumor characteristics affect
outcomes?
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0599-131115.pdf
June 20, 2013 - The scope of this topic, including populations, interventions, comparators, and outcomes, will
be further … The nominator is interested in the comparative effectiveness of physician house calls on
Summary: outcomes … The nominator acknowledges
uncertainty regarding the comparative effectiveness related to outcomes such … admissions, Health care
utilization (e.g., ER visits, hospital admissions), cost, relevant disease-specific outcomes … Key Questions What is the comparative effectiveness of physician house calls on outcomes