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Showing results for "outcomes".

2781. The Use of Conjoint Analysis to Elicit Patient Preferences in Selecting Treatment Endpoints (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/mcda-johnson.pdf
      August 27, 2012 - Social Science and Medicine, 1995 Slide 4 Types of Self-Reported Data Patient- Reported Outcomes … Health-State Utilities Stated Preferences Patient- Reported Outcomes Health-State Utilities …  Duration PREFERENCE UTILITY  Clinical Outcomes  Duration  Treatment factors – Side … Poster presented at the International Society for Pharmacoeconomics and Outcomes Research 16th Annual … Poster presented at the International Society for Pharmacoeconomics and Outcomes Research 16th Annual

2782. Grading_didactic_faculty_approved (ppt file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/grading.ppt
      January 01, 2010 - bodies of evidence are needed to link the intervention to health outcomes. … Intermediate or surrogate outcomes instead of health or patient-centered outcomes Example: laboratory … /proxy outcomes Better strength of evidence Indirect (e.g., A vs. … Thus, strength of evidence should relate to those important outcomes. … For some treatments, data may be lacking about one or more of the outcomes.

2783. Ankyloglossia-protocol-140630 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/ankyloglossia_research-protocol.pdf
      June 30, 2014 - , breastfeeding mechanics and related outcomes typically improved. … This review did not evaluate non-surgical management or broader outcomes. … Key Question 1 is focused on breastfeeding outcomes in infants treated for ankyloglossia. … Deciding which outcomes are to be extracted. … Grading the Strength of Evidence (SOE) for Major Comparisons and Outcomes.

2784. Treatments for Adults with Schizophrenia: A Systematic Review (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/schizophrenia-adult_research-protocol.pdf
      September 23, 2016 - • Outcomes for each question: o Key Questions 1 and 2: Benefits Outcomes: § Functional • Improvements … For key outcomes, we will update meta- analyses. … based on the optimal information size for selected outcomes. … outcomes measured in included studies. … Functional outcomes (e.g., social, occupational) 2.

2785. Methods Guide for Comparative Effectiveness Reviews - Avoiding Bias in Selecting Studies (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-bias_methods.pdf
      February 01, 2013 - Outcome Described as effectiveness outcomes Reviewers determine whether specific outcomes are … outcomes, thus making the intervention seem more effective than if clinical outcomes are considered … Without prespecifying that long term outcomes are essential and only reporting short term outcomes, … Outcomes Regardless of the topic, SRs should focus on assessing a range of patient-centered outcomes … , while under-reporting the effect on long term outcomes.

2786. Vaginal Birth After Cesarean: Developing and Prioritizing a Future Research Agenda (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/cesarean-birth-future_research.pdf
      August 09, 2012 - Director, EPC Program Task Order Officer Center for Outcomes and Evidence Center for Outcomes … Maternal and infant outcomes: 1. … risk of adverse outcomes with TOL or ERCD. 10. … Short- and long-term outcomes after cesarean section. … ERCD and maternal/infant outcomes 8.

2787. Treatments for Fibromyalgia in Adult Subgroups | Effective Health Care (EHC) Program
      effectivehealthcare.ahrq.gov/products/fibromyalgia/research-protocol
      April 03, 2014 - Outcomes Final health outcomes: KQ 1 and some potential measures of each outcome: Overall pain (Visual … data may have been related to real outcomes. … We will emphasize patient-centered outcomes in the evidence synthesis. … Were outcomes assessors blinded? Yes Who assessed outcomes?   … Yes     No Not all prespecified outcomes reported, subscales not prespecified reported, outcomes

2788. Liver-Cancer Research-Protocol (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/liver-cancer_research-protocol.pdf
      July 24, 2013 - ● Outcomes for Each Key Question o Key Question 1  Diagnostic outcomes include:  Detection … Outcomes Diagnostic outcomes include: • Detection rates of tumors identified by surveillance. … Intermediate outcomes include: • Effects on diagnostic thinking. … Outcomes Diagnostic outcomes include: • Test performance (e.g., sensitivity and specificity) for … Outcomes Diagnostic outcomes include: • Measures for accuracy of staging (stage reclassification).

2789. Prostate-Cancer-Therapies-Update Research-Protocol (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/prostate-cancer-therapies-update_research-protocol.pdf
      April 01, 2013 - • No RCT reported head-to-head comparisons of treatment outcomes stratified by race/ethnicity. … the majority reporting biochemical progression or recurrence as the primary outcomes. … potential for disease progression) affect the outcomes of these therapies overall and differentially … case volume and outcomes Studies using administrative data that measured outcomes in different locations … Outcomes • The primary outcome is overall mortality or survival.

2790. Evidence Report on the (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/atypical-antipsychotics-off-label-update_research-protocol.pdf
      May 19, 2010 - Outcomes: For efficacy, we will report commonly used objective outcomes such as symptom scores, response … Outcomes are listed in appendix A. … Outcomes are listed in appendix A. … outcomes are the same as in KQ1 and KQ2. … For efficacy/effectiveness outcomes, a statistician will extract data.

2791. Study Objectives and Questions for Observational Comparative Effectiveness Research
      effectivehealthcare.ahrq.gov/sites/default/files/study-objectives-and-questions-chapter-1.pptx
      January 01, 2013 - and investigators are willing to accept a priori Describe the meaningful magnitude of change in the outcomes … investigators are willing to accept a priori; and describe the meaningful magnitude of change in the outcomes … Outcomes: What are the outcomes of interest? … Timing: What is the time frame of interest for assessing outcomes? … Are decisionmakers interested in short-term or long-term outcomes?

2792. Progestogens-Preterm-Birth Executive (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/progestogens-preterm-birth_executive.pdf
      September 01, 2012 - • Longer term outcomes (e.g., neurodevelopmental delay and future reproductive outcomes)? KQ2. … • Longer term outcomes? KQ3. … information on modifiers of treatment outcomes. … Mean gestational age at birth and other outcomes did not differ. … Committee on Understanding Premature Birth and Assuring Healthy Outcomes.

2793. Meditation Executive (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/meditation_executive.pdf
      January 01, 2014 - While some of the outcomes were primary outcomes, many were secondary outcomes, and the studies may … not have been appropriately powered to detect changes in secondary outcomes. … Fifth, positive outcomes are a key focus of meditative practices. … However, most trials did not include positive outcomes as primary or even secondary outcomes. … There are reasons why a large number of outcomes lacked sufficient evidence.

2794. Treatment Strategies for Patients With Peripheral Artery Disease | Effective Health Care (EHC) Program
      effectivehealthcare.ahrq.gov/products/peripheral-artery-disease-treatment/research
      May 29, 2013 - dual antiplatelet therapy (DAPT)—clopidogrel plus aspirin—had no impact on composite or individual outcomes … DAPT and aspirin alone on nonfatal stroke and composite vascular events and was inconclusive for other outcomes … and aspirin alone in cardiovascular events or mortality at 6 months but was underpowered for those outcomes … depict relative effect sizes and identify which treatments are clearly superior to placebo for which outcomes … from observational studies, and the heterogeneity of the results makes conclusions for all clinical outcomes

2795. Ankyloglossia | Effective Health Care (EHC) Program
      effectivehealthcare.ahrq.gov/products/ankyloglossia/research-protocol
      June 30, 2014 - , breastfeeding mechanics and related outcomes typically improved. … The most recent systematic review, published in 2013, assessed outcomes related to breastfeeding and … This review did not evaluate non-surgical management or broader outcomes. … Key Question 1 is focused on breastfeeding outcomes in infants treated for ankyloglossia. … Deciding which outcomes are to be extracted We identified outcomes based on our clinical expertise

2796. FRN 30: Outpatient Case Management for Adults With Medical Illnesses and Complex Care Needs: Future Research Needs (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/case-management-future_research.pdf
      June 01, 2015 - Director, EPC Program Task Order Officer Center for Outcomes and Evidence Center for Outcomes … Patient-centered outcomes, including mortality, quality of life, disease-specific health outcomes, … Patient-centered outcomes, including mortality, quality of life, disease-specific health outcomes, … D.3 Link components and outcomes Mayo, 20119 To determine impact of CM on any patient outcomes, … allowing diversity of outcomes across patients.

2797. PCA3 Testing in the Diagnosis and Management of Prostate Cancer: Future Research Needs (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/prostate-cancer-antigen-3-gene_research.pdf
      April 01, 2013 - Does the addition of PCA3 testing change long-term health outcomes in prostate screening? … Does addition of PCA3 testing change long-term health outcomes in prostate screening? … The strength of evidence for these outcomes was insufficient. … The strength of evidence for all comparators and outcomes was insufficient. … Uncertainty of impact of PCA3 in biopsy decisionmaking on long term health outcomes. 7.

2798. Rti-Item-Bank Research (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/rti-item-bank_research.pdf
      August 01, 2013 - Director and Task Order Officer Evidence-based Practice Program Center for Outcomes and Evidence … X Q9 Are any important primary outcomes missing from the results? … Q15 Are the statistical methods used to assess the primary benefit outcomes inadequate? … C-6 Q9: Are any important primary outcomes missing from the results? … PI: Yes, important outcomes missing .........................

2799. Prognostic Tests (ppt file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/medical-test-reviews-prognostic.ppt
      June 01, 2012 - For this scenario, the precision and accuracy estimates of the outcomes for each prognostic group are … Outcomes Time-dependent probabilities (time-to-event curves) of what is being predicted, changes or … Clinical outcomes: Would use of the prognostic test improve patient outcomes? … A clinical outcomes study simply asks if using the new test would improve patient outcomes. … Lastly, a cost-effectiveness study evaluates whether any improvements in patient outcomes warrant the

2800. Assessing-The-Risk-Of-Bias-In-Systematic-Reviews-Of-Health-Care-Interventions (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/assessing-the-risk-of-bias-in-systematic-reviews-of-health-care-interventions-01.pdf
      May 01, 2005 - For some studies, all outcomes may have the same sources of bias; for other studies, the sources of … Some have elected to rate outcomes from poorly reported studies as having high risk of bias. … Reviewers of topics that focus on short-term clinical outcomes may expect a low rate of attrition. … Selectively reporting outcomes based on the findings • Outcomes are prespecified and all prespecified … Framing the question and deciding on important outcomes.