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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/autism-interventions-future_research.pdf
September 01, 2012 - , and social outcomes? … , and social outcomes? … , and social outcomes? … , and social outcomes? … , and social outcomes?
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/grading.ppt
January 01, 2010 - bodies of evidence are needed to link the intervention to health outcomes. … Intermediate or surrogate outcomes instead of health or patient-centered outcomes
Example: laboratory … /proxy outcomes
Better strength of evidence
Indirect (e.g., A vs. … Thus, strength of evidence should relate to those important outcomes. … For some treatments, data may be lacking about one or more of the outcomes.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/ankyloglossia_research-protocol.pdf
June 30, 2014 - ,
breastfeeding mechanics and related outcomes typically improved. … This review did not
evaluate non-surgical management or broader outcomes. … Key Question 1 is focused on breastfeeding
outcomes in infants treated for ankyloglossia. … Deciding which outcomes are to be extracted. … Grading the Strength of Evidence (SOE) for Major Comparisons and Outcomes.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/methods-guidance-bias_methods.pdf
February 01, 2013 - Outcome
Described as
effectiveness
outcomes
Reviewers determine whether
specific outcomes are … outcomes, thus making the
intervention seem more effective than
if clinical outcomes are considered … Without prespecifying that long term
outcomes are essential and only
reporting short term outcomes, … Outcomes
Regardless of the topic, SRs should focus on assessing a range of patient-centered outcomes … , while under-reporting the effect on long term outcomes.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/antipsychotics-children-update_executive.pdf
January 01, 2018 - Outcomes KQ1: intermediate and effectiveness outcomes (see following list of outcomes). … and effectiveness
outcomes are summarized below. … The studies did not report any effectiveness outcomes. … for the outcomes of
weight and BMI. … These outcomes represent two of the key
outcomes that were reported by the most studies (weight,
n
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/preoperative-testing_executive.pdf
January 01, 2014 - normal) as predictors of outcomes. … How do outcomes vary by—
a. … How do
outcomes vary by—
a. … Outcomes of Interest
For Key Question 1, outcomes were confined to those
related to the conduct of … No other outcomes were
reported.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/cystic-fibrosis-hgh_research-protocol.pdf
August 22, 2008 - and health outcomes. … Regarding the intermediate outcomes within KQ1,
there are distinct clusters of outcomes which may be … Because of the variation in reporting, these outcomes are not meta-
analyzable. … When
given multiple height and weight outcomes, the most commonly reported outcomes will be
selected … A separate grade will be
given for all major outcomes, including benefits and harms.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/atypical-antipsychotics-off-label-update_research-protocol.pdf
May 19, 2010 - Outcomes: For efficacy, we will report commonly used objective outcomes such as symptom
scores, response … Outcomes are listed in appendix A. … Outcomes are listed in appendix A. … outcomes are the same as in KQ1 and KQ2. … For efficacy/effectiveness outcomes, a statistician will extract data.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/schizophrenia-adult_research-protocol.pdf
September 23, 2016 - • Outcomes for each question:
o Key Questions 1 and 2:
Benefits Outcomes:
§ Functional
• Improvements … For key outcomes, we will update meta-
analyses. … based on the optimal information size for selected
outcomes. … outcomes measured in included studies. … Functional outcomes (e.g., social, occupational)
2.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/mcda-johnson.pdf
August 27, 2012 - Social Science and Medicine, 1995
Slide 4
Types of Self-Reported Data
Patient-
Reported
Outcomes … Health-State
Utilities
Stated
Preferences
Patient-
Reported
Outcomes
Health-State
Utilities … Duration
PREFERENCE UTILITY
Clinical Outcomes
Duration
Treatment factors
– Side … Poster presented at the International
Society for Pharmacoeconomics and Outcomes Research 16th Annual … Poster presented at the International
Society for Pharmacoeconomics and Outcomes Research 16th Annual
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/cesarean-birth-future_research.pdf
August 09, 2012 - Director, EPC Program Task Order Officer
Center for Outcomes and Evidence Center for Outcomes … Maternal and infant outcomes:
1. … risk of adverse outcomes with TOL or ERCD.
10. … Short- and long-term
outcomes after cesarean section. … ERCD and maternal/infant outcomes
8.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/liver-cancer_research-protocol.pdf
July 24, 2013 - ● Outcomes for Each Key Question
o Key Question 1
Diagnostic outcomes include:
Detection … Outcomes Diagnostic outcomes include:
• Detection rates of tumors identified by surveillance. … Intermediate outcomes include:
• Effects on diagnostic thinking. … Outcomes Diagnostic outcomes include:
• Test performance (e.g., sensitivity and specificity) for … Outcomes Diagnostic outcomes include:
• Measures for accuracy of staging (stage reclassification).
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/meditation_executive.pdf
January 01, 2014 - While
some of the outcomes were primary outcomes, many were
secondary outcomes, and the studies may … not have been
appropriately powered to detect changes in secondary
outcomes. … Fifth, positive outcomes are a key focus of meditative
practices. … However, most trials did not include positive
outcomes as primary or even secondary outcomes. … There are reasons why a large number of outcomes
lacked sufficient evidence.
-
effectivehealthcare-admin.ahrq.gov/products/survival-quality/research
November 01, 2017 - efficacy and safety) of a new drug, what evidence exists on the association of PFS with QOL and related outcomes … KQ2 sought to determine an association between PFS and QOL or related outcomes, such as disease symptoms … It focused on the relationship between PFS, an outcome, and other outcomes of importance to patients. … Defining the relationship between PFS and QOL or other patient-reported outcomes (PRO) involves considering … confounding relationships, for considering further study of the relation between PFS and QOL-related outcomes
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/prostate-cancer-therapies-update_research-protocol.pdf
April 01, 2013 - • No RCT reported head-to-head comparisons of treatment outcomes stratified by
race/ethnicity. … the majority reporting biochemical progression or
recurrence as the primary outcomes. … potential for disease progression) affect the outcomes of these therapies overall and
differentially … case volume and outcomes
Studies using administrative data that measured outcomes in
different locations … Outcomes
• The primary outcome is overall mortality or survival.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/progestogens-preterm-birth_executive.pdf
September 01, 2012 - • Longer term outcomes (e.g., neurodevelopmental
delay and future reproductive outcomes)?
KQ2. … • Longer term outcomes?
KQ3. … information on modifiers of treatment outcomes. … Mean gestational age at
birth and other outcomes did not differ. … Committee
on Understanding Premature Birth and Assuring Healthy
Outcomes.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/medical-test-reviews-prognostic.ppt
June 01, 2012 - For this scenario, the precision and accuracy estimates of the outcomes for each prognostic group are … Outcomes Time-dependent probabilities (time-to-event curves) of what is being predicted, changes or … Clinical outcomes: Would use of the prognostic test improve patient outcomes? … A clinical outcomes study simply asks if using the new test would improve patient outcomes. … Lastly, a cost-effectiveness study evaluates whether any improvements in patient outcomes warrant the
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/medical-test-reviews-prognostic.ppt
June 01, 2012 - For this scenario, the precision and accuracy estimates of the outcomes for each prognostic group are … Outcomes Time-dependent probabilities (time-to-event curves) of what is being predicted, changes or … Clinical outcomes: Would use of the prognostic test improve patient outcomes? … A clinical outcomes study simply asks if using the new test would improve patient outcomes. … Lastly, a cost-effectiveness study evaluates whether any improvements in patient outcomes warrant the
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/registries-guide_executive.pdf
April 01, 2007 - Layout 1
User’s Guide to
Registries Evaluating
Patient Outcomes:
Summary
Advancing Excellence in … Registries for Evaluating Patient Outcomes: A User’s Guide. … • Operational definitions of outcomes are clearly defined. … • The followup period is reasonably sufficient to capture the main outcomes of interest. … • The followup period is sufficient to capture outcomes of interest.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/product/pdf/assessing-the-risk-of-bias-in-systematic-reviews-of-health-care-interventions-01.pdf
May 01, 2005 - For some studies, all outcomes
may have the same sources of bias; for other studies, the sources of … Some
have elected to rate outcomes from poorly reported studies as having high risk of bias. … Reviewers of topics that focus on short-term clinical
outcomes may expect a low rate of attrition. … Selectively reporting outcomes based on the
findings
• Outcomes are prespecified and all prespecified … Framing the question and deciding
on important outcomes.