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Showing results for "outcomes".

221. Statistical Design and Analytic Considerations for N-of-1 Trials (Chapter 4) | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/n-1-trials/research-2014-1
     August 01, 2019 - Often the outcomes differ so fundamentally that forming a composite becomes difficult. … Models for Continuous Outcomes A variety of different models can be constructed when the outcomes are … regression; count outcomes use Poisson regression; and categorical outcomes use categorical logistic … for multiple outcomes can accommodate the patient-centered nature of n-of-1 trials. … the burden on users to digest trial results across multiple outcomes.  

222. Comparative Effectiveness of Terbutaline Pump for the Prevention of Preterm Birth | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/preterm-birth-terbutaline-pump/research-protocol
     December 01, 2019 - In utero beta 2 adrenergic agonist exposure and adverse neurophysiologic and behavioral outcomes. … Point 2: These outcomes were suggested by the TEP as additional outcomes of interest. C. … Primary outcomes Clinical neonatal outcomes (bronchopulmonary dysplasia, necrotizing enterocolitis … All information available on neonatal outcomes will be assessed. … For rare outcomes, only studies with events recorded will be included in combined estimates.

223. Omega−3 Fatty Acids and Cardiovascular Disease: An Updated Systematic Review (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/fatty-acids-cardiovascular-disease_executive.pdf
     August 01, 2016 - of n-3 FA intake and outcomes. … What are the outcomes of interest (intermediate and health outcomes)? 4. … Clinical Event Outcomes, RCTs No RCTs reported clinical event outcomes for comparisons of total n-3 … Clinical Event Outcomes, RCTs Regarding clinical event outcomes, one trial in an at risk population … Intermediate Outcomes, RCTs Two RCTs evaluated BP or lipid outcomes.

224. Nonoperative and Operative Treatments for Rotator Cuff Tears: Future Research Needs | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/rotator-cuff-tears-future/research
     December 01, 2019 - The outcomes included health-related quality of life, return to work, pain, shoulder function, rotator … However, adverse treatment effects and the impact of baseline patient and injury characteristics on outcomes … The literature limitations included low study quality, disparate treatments and outcomes, small sample … was of moderate quality but often lacked control for the effects of potential confounding factors on outcomes … The focus of this project was on treatment and post-treatment outcomes rather than complications, because

225. Comparative Effectiveness of Surgical Options for Inguinal Hernia | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/inguinal-hernia/research-protocol
     December 01, 2019 - Patient-oriented effectiveness outcomes and adverse events (see list of outcomes at the bottom … are not likely to be predictive of current outcomes. … other outcomes. … However, full results of all included outcomes will be available in appendices. F. … Depending on time constraints of the review, we may grade additional outcomes as well.

226. Maternal Morbidity and Mortality (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/product/pdf/mmm-draft-protocol-amendment.pdf
     February 02, 2022 - Studies are not excluded based on maternal health outcomes. … Studies that report only neonatal or infant outcomes are excluded. … Maternal health outcomes for incarcerated women: A scoping review. … Studies are not excluded based on maternal health outcomes. … Studies that report only neonatal or infant outcomes are excluded.

227. Layout 1 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/renal-artery-stenosis_executive.pdf
     October 01, 2006 - of surgery and medical treatment reported cardiovascular outcomes. … No study of medical interventions reported cardiovascular outcomes. … The reviewed studies did not report any indicators that may predict improved outcomes. … • Studies that compared stent placement to no stent placement found no difference in outcomes. … Medical treatment N/A • No study evaluated potential predictors of outcomes.

228. Postpartum Care for Women Up to One Year After Pregnancy (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/product/pdf/postpartum-care-one-year-protocol-amendment.pdf
     April 25, 2022 - With the goal of improving health outcomes and reducing disparities, the American Rescue Plan Act of … Does this relationship differ by timing of outcomes, specifically within 6 days postpartum, between … (* and bold font denotes important outcomes that will be used when developing Strength of Evidence … For KQ 1a, timing of interest for outcomes is within 3 months after giving birth. … We determined the relative importance of the outcomes with input from the TEP.

229. Omega 3 Fatty Acids and Maternal and Child Health | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/omega-3-maternity/research-protocol
     January 01, 2020 - *Several additional outcomes were added to the original key questions. They appear in bold. … What are the outcomes of interest (intermediate and health outcomes)? … The populations are expanded to accommodate the expanded outcomes of interest. … Outcomes data, including clinical outcomes and intermediate outcomes (concentrations of biomarkers), … Vitamin D and Calcium: A Systematic Review of Health Outcomes (Update).

230. Hit-Patient-Care Executive (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/hit-patient-care_executive.pdf
     June 01, 2012 - Health care process outcomes (e.g., receiving appropriate treatment) b. … Clinical outcomes for patients (including quality of life) c. … The outcomes measured were highly variable. … Most of the existing evidence focuses on process outcomes, clinical outcomes, and intermediate outcomes … While real improvements in all outcomes are the ultimate goal, standardization of core outcomes pertinent

231. The Performance of Fusion Procedures for Degenerative Disease of the Lumbar Spine (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/lumbar-spinal-fusion-key-question.pdf
     January 01, 2023 - KQ6: For adult patients undergoing lumbar fusion, do clinical outcomes vary between the use of autografts … BACKGROUND The Patient-Centered Outcomes Research Institute (PCORI) is partnering with the Agency … PICOTSS Framework (population, interventions, comparators, outcomes, timing, settings, study design) … measured at least 12 months after surgical procedure Outcomes measured over a 6-month period … following the procedure Outcomes measured at least 12 months after surgical procedure Outcomes

232. Cer-242-Radiation-Therapy-Brain-Metastases-Evidence-Summary (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/cer-242-radiation-therapy-brain-metastases-evidence-summary.pdf
     June 01, 2021 - • There is insufficient evidence for important outcomes including quality of life, functional status … • Evidence was insufficient for several SRS evaluations and outcomes of interest. … • There is insufficient evidence for important clinical outcomes including cognitive effects and … A Technical Expert Panel advised on key outcomes: overall survival, disease-free survival, deaths due … Evidence was insufficient for several SRS evaluations and outcomes of interest.

233. A Bayesian Missing Data Framework for Multiple Continuous Outcome Mixed Treatment Comparisons | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/indirect-comparisons/research-2013
     November 01, 2017 - Many randomized clinical trials report multiple outcomes with possible inherent correlations, but there … missing data methods to obtain novel and improved Bayesian approaches to MTCs for multiple continuous outcomes … treat missing data the same as unknown parameters and to incorporate correlation structure between outcomes … Bayesian treatment ranks based on a sensible scoring system incorporating weights for the multiple outcomes … Ignoring missing data or correlation between outcomes can produce biased MTC estimates leading to high

234. Lower Limb Prosthesis | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/prosthesis/research-protocol
     January 01, 2019 - use validated instruments and outcomes. … Predictive tests should be valued with respect to their ability to predict future outcomes. … However, outcomes are determined by the whole patient management strategy which involves the baseline … What is the association between pre-prescription assessment techniques and validated outcomes with the … What functional outcomes that have been for measurement properties were used in these studies?

235. Chapter 2. Developing the Topic and Structuring Systematic Reviews of Medical Tests: Utility of PICOTS, Analytic Frameworks, Decision Trees, and Other Frameworks | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/methods-guidance-tests-topics/methods
     December 01, 2019 - outcomes link a medical test to improved clinical outcomes. … which intermediate outcomes link a medical test to improved clinical outcomes, compared to an existing … More commonly, evidence about outcomes in support of the claim relates to intermediate outcomes such … , intervention, and clinical outcomes are specifically shown. … Since the impact of tests on clinical outcomes usually depends on downstream interventions, analytic

236. Obesity Prevention and Control | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/obesity-research-methods/research-protocol
     January 01, 2019 - When articles report neighborhood outcomes that meet the inclusion criteria, we will record such outcomes … (e.g., urban renewal) in addition to the primary outcomes. … take the following approach: Abstract a list of obesity measures, behavioral outcomes, and co-outcomes … outcomes). … See Appendix B for list of outcomes Other outcomes (e.g., food environment, physical activity environment

237. Making Healthcare Safer IV: Opioid Stewardship | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/mhs4-opioid-stewardship/protocol
     September 01, 2023 - of interest are clinical outcomes. … Secondary outcomes of interest are prescribing/ordering outcomes and process outcomes, if they are reported … in studies that also report clinical outcomes … •    Clinical outcomes:  Health care utilization (focusing on emergency department use and … outcomes or implementation outcomes without clinical outcomes) Timing Systematic reviews

238. EHC Protocol: Making Healthcare Safer IV: Opioid Stewardship (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/mhs4-opioid-stewardship-protocol.pdf
     July 01, 2023 - of interest are clinical outcomes. … Secondary outcomes of interest are prescribing/ordering outcomes and process outcomes, if they are reported … in studies that also report clinical outcomes … and facilitators o Cost, staffing, time Studies with prescribing/ordering outcomes or process outcomes … or implementation outcomes without clinical outcomes) Timing • Systematic reviews published since

239. Dementia-Nursing-Home-Characteristics Executive (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/dementia-nursing-home-characteristics_executive.pdf
     October 01, 2012 - for people with dementia Psychosocial outcomes for people with dementia Health outcomes for informal … Outcomes of interest were quite broad: • Health outcomes for people with dementia, such as pain or … Health Outcomes for People With Dementia Table A summarizes the SOE for health outcomes for people with … Psychosocial Outcomes for People With Dementia Table B summarizes the SOE for psychosocial outcomes … of psychosocial outcomes.

240. Diabetes Medications for Adults with Type 2 Diabetes: An Update Focused on Monotherapy and Add-on Therapy to Metformin | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/diabetes-update-2015/research-protocol
     December 01, 2019 - We will not review these outcomes for any medication classes or comparisons except those including … Outcomes for each question The intermediate outcomes included in KQ1 will be: Hemoglobin A1c … of HbA1c, long-term outcomes, and select safety outcomes given the high strength of evidence from … Outcomes* We will include studies addressing the following intermediate outcomes for KQ1: … Results of a reevaluation of cardiovascular outcomes in the RECORD trial.