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effectivehealthcare.ahrq.gov/sites/default/files/related_files/medical-test-reviews-prognostic.ppt
June 01, 2012 - Perform appropriate statistical analyses based on outcome probabilities. … Conduct meta-analyses of estimates of outcome probabilities. … Were the results ascertained without knowledge of the outcome? … Ideally, the classification of outcome probabilities into prognostic groups should be based on outcome … of outcome probabilities from different studies.
-
effectivehealthcare.ahrq.gov/sites/default/files/medical-test-reviews-prognostic.ppt
June 01, 2012 - Perform appropriate statistical analyses based on outcome probabilities. … Conduct meta-analyses of estimates of outcome probabilities. … Were the results ascertained without knowledge of the outcome? … Ideally, the classification of outcome probabilities into prognostic groups should be based on outcome … of outcome probabilities from different studies.
-
effectivehealthcare.ahrq.gov/sites/default/files/ch_10-user-guide-to-ocer_130129.pdf
January 01, 2011 - The appropriate analytic technique is dictated by the characteristics of
the study outcome, exposure … numbers of covariates and are particularly favorable in studies having a common
exposure and rare outcome … Variables that are potentially on the
pathway from treatment to outcome are not
controlled for, as … together be used to essentially back
out the effect of the treatment on the outcome. … An instrument also must not
affect the outcome except through the treatment.
-
effectivehealthcare.ahrq.gov/sites/default/files/considerations-for-statistical-chapter-10.pptx
January 01, 2013 - DEcIDE Center (Quintiles Outcome, Cambridge, MA) for the Agency for Healthcare Research and Quality … For instance, for logistic regression, as long as the number of outcome events per covariate included … They include covariates that are true confounders or at least related to study outcome. … the treatment and is also unrelated to the confounders of the treatment-outcome relationship. … be used to essentially back out the effect of the treatment on the outcome.
-
effectivehealthcare.ahrq.gov/sites/default/files/suppl-2-user-guide-to-ocer_130129.pdf
January 01, 2011 - often referred to as the factual
outcome. … if the outcome experienced
would have been different under an alternative
treatment level. … Figure S2.3 indicates
that treatment (A) and outcome (Y) have a
common cause (C
4
). … confounding as an open pathway
between treatment and outcome. … or risk factors
for the outcome.
-
effectivehealthcare.ahrq.gov/sites/default/files/ch_6-user-guide-to-ocer_130129.pdf
October 30, 2012 - Outcome Definition and Measurement
Figure 6.1. … Outcome Measurement
Properties
The properties of outcome measures that are an
integral part of an … Outcome Definition and Measurement
Table 6.2. … of the primary outcome
of interest—that is, whether the outcome is
measured and expressed as a dichotomous … Outcome Definition and Measurement
Checklist: Guidance and key considerations for outcome selection
-
effectivehealthcare.ahrq.gov/sites/default/files/cer-235-pharma-nonpharm-ptsd-update-appendix-g-1.xlsx
November 12, 2020 - Performance Bias Domain: Participants Masked or Objective Outcome Assessment? … Detection Bias Domain: Outcome Assessors Masked? … Other Considerations: Were outcome measures equal, valid, and reliable? … :
• No details/not reported Yes
• Study used a validated PTSD assessment method
No
• Used different outcome … domain are rated as no or unclear
Medium:
• Possible potential for biased findings on the primary outcome
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-235-pharma-nonpharm-ptsd-update-appendix-g-1.xlsx
November 12, 2020 - Performance Bias Domain: Participants Masked or Objective Outcome Assessment? … Detection Bias Domain: Outcome Assessors Masked? … Other Considerations: Were outcome measures equal, valid, and reliable? … :
• No details/not reported Yes
• Study used a validated PTSD assessment method
No
• Used different outcome … domain are rated as no or unclear
Medium:
• Possible potential for biased findings on the primary outcome
-
effectivehealthcare.ahrq.gov/products/methods-guidance-reporting-bias
November 18, 2013 - Finding Grey Literature Evidence and Assessing for Outcome and Analysis Reporting Biases When Comparing … Methods Guide – Chapter
Finding Grey Literature Evidence and Assessing for Outcome
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-reporting-bias_methods.pdf
November 01, 2013 - An example of selective outcome reporting might be when a trial protocol indicates the
primary outcome … omission, upgrading
from secondary to primary outcome, new primary outcome introduction, underreporting … Principles for Assessing Reporting Bias
Outcome Level Assessment
The risk of selective outcome and … • As described below, efforts should routinely be made to identify outcome level selective
outcome … that outcome.
-
effectivehealthcare.ahrq.gov/sites/default/files/study-design-considerations-chapter-2.pptx
January 01, 2013 - DEcIDE Center (Quintiles Outcome, Cambridge, MA) for the Agency for Healthcare Research and Quality … Cohort members with the outcome prevalent at baseline need to be excluded. … of exposure during a brief time window before the outcome occurred. … The assumption that the outcome does not affect treatment will often be implausible. … Furthermore, it precludes the study of mortality as an outcome.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd-5-protocol-update-2023.pdf
January 01, 2023 - • Studies reporting only individual symptoms
or symptom clusters without overall PTSD
outcome
• … Number of participants who completed the outcome assessment
8. … Outcome type (PTSD diagnostic change, clinically meaningful response)
2. Outcome definition
3. … method of measuring the outcome inappropriate? … measurements (e.g. scales, definitions, time points) within the outcome domain?
-
effectivehealthcare.ahrq.gov/sites/default/files/whitepaper4-bossuyt02262010-2.pdf
January 01, 2009 - This requires an understanding of how tests can affect
patient outcome. … Existing testing trials and studies do not always have a health outcome as the primary
outcome measure … These changes may amplify or attenuate the intended effect on the primary clinical
outcome. … Direct and management effects on patient outcome
12
Figure 2. … Full range of effects of testing on patient outcome
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/outcomes-testing-evaluation_research.pdf
January 01, 2009 - This requires an understanding of how tests can affect
patient outcome. … Existing testing trials and studies do not always have a health outcome as the primary
outcome measure … These changes may amplify or attenuate the intended effect on the primary clinical
outcome. … Direct and management effects on patient outcome
12
Figure 2. … Full range of effects of testing on patient outcome
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-binary-outcomes-evaluation_research.pdf
March 11, 2013 - second outcome. … suggest flow of
information from the second outcome to the first outcome.
! … suggest flow of
information from the first outcome to the second outcome.
! … second outcome. … second
outcome.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/strategies-integrating-behavioral-health-RoB-tables.xlsx
September 25, 2023 - Missing Data Similar for Group Comparable groups maintained Described Interventions and Comparators Outcome … measurement similar Blind outcome assessor Final rating
Asarnow, 2005 Yes Yes Yes Yes Yes Yes Yes Yes … measurement similar Blind outcome assessor Final rating
Balasubramanian, 2018 Yes No NA/NR NA No Yes … measurement similar Blind outcome assessor Final rating
Abu-Ghname, 2019 Yes No NA NA Yes Yes Yes NA … measurement similar Blind outcome assessor Final rating
Berge, 2017 Yes NA NA NA NA Yes No Yes Yes
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs-IV-surgical-report-cards.pdf
July 01, 2023 - Center Rapid Response Protocol
Project Title: Making Healthcare Safer IV: Use of Report
Cards and Outcome … What is the reported rationale for the use of report cards and outcome measurements
to prevent, report … What are common barriers and facilitators to implementing report cards and outcome
measurements to … What resources (e.g., cost, staff, time) are required for implementation of report cards
and outcome … The use of surgical report cards and outcome measurements to improve the safety of
surgical care was
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-report-creating-efficiencies-extraction-data.pdf
August 01, 2021 - name, primary outcome time point, secondary outcome name,
secondary outcome time point, funding organization … Primary outcome(s) 75 (100.0) 75 (100.0) 53 (70.7) 62 (82.7) 95/375
(25.3)
Primary outcome time … time point (n = 50/86, 58.1%), secondary outcome(s) (n = 35/53, 66.0%), and
secondary outcome time … Primary outcome(s) 95 78 74 (94.9) 55 (70.5) 19 (24.4)
Primary outcome time
point
76 86 78 (90.7 … )
Secondary outcome(s) 23 (30.7) 31 (41.3) 21 (28.0)
Secondary outcome time
point
15 (20.0) 27 (
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/models-care-adult-survivors-childhood-cancer-evidence-summary.pdf
February 01, 2022 - Our context, mechanism, and outcome
hypotheses suggest how the relationships illustrated in our theory … Context-mechanism-outcome hypotheses regarding how models of care that include
primary care could be … (Intermediate)
OUTCOME
(Final)
A) the availability of
survivorship care plans,
guidelines, … Context-mechanism-outcome hypotheses regarding how models of care that include
primary care could be … (Intermediate)
OUTCOME
(Final)
A) the availability of
survivorship care plans,
guidelines,
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0718-140819.pdf
March 11, 2013 - Staff-Generated PICO
Primary outcome: HAI rates in patients
Population(s): Patients in hospitals or … light); coating with disinfectants (e.g. copper)
Comparator(s): Different method(s) or benchmark
Outcome … While reducing HAI in patients is the
paramount outcome of interest, it is well established that these … is an essential
aspect of reducing HAIs, and evaluation of evidence to achieve this intermediate
outcome … light); coating with disinfectants (e.g. copper)
Comparator(s): Different method(s) or benchmark
Outcome