-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cystic-fibrosis-hgh_appendixes.pdf
January 01, 2009 - Quality of
life as a treatment outcome in patients with cystic fibrosis. … Outcome of assisted
ventilation for acute respiratory failure in cystic fibrosis. … Helps
determine the degree of importance of each variable for a given outcome. … Outcome of patients with cystic fibrosis
awaiting lung transplantation. … One-
year outcome after severe pulmonary
exacerbation in adults with cystic fibrosis.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/diabetic-neuropathy_research-protocol.pdf
May 09, 2016 - contribute to long-term
diabetic complications such as foot ulcerations.14 Although DPN is not an outcome … review addressed a
variety of issues with treatment but focused mainly on pharmacotherapy and the outcome … all causes of peripheral neuropathy and recommended a number of agents and also
included a safety outcome … or physical therapy modalities
Comparator(s): Active interventions as well as usual care/placebo
Outcome … Benefits (KQ1a and KQ1b):
o Incident or recurrent foot ulcer (excluding healing of ulcer as the outcome
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/urinary-incontinence-update_research-protocol.pdf
June 06, 2017 - • To summarize information on how women with UI define a successful outcome,
and to highlight data … What is the available evidence concerning adult women’s conceptions of what defines a
successful outcome … will add patient-centered outcomes identified from the contextual
question on how patients define outcome … These analyses will be feasible only if
sufficient studies report on the same outcome(s) in sufficiently … Following
the standard AHRQ approach, for each comparison of interventions, and for each
outcome, we
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effectivehealthcare.ahrq.gov/sites/default/files/cer30_hip-fracture-pain-executive-summary_20110517.pdf
May 01, 2011 - Common weaknesses in the design of the studies
included lack of independent blind outcome assessment … There was no significant
difference between groups for either outcome (OR
1.25; 95% CI 0.42, 3.76; … Standardization of outcomes and outcome
measures will allow easier and meaningful comparisons
across … outcome assessment instruments, adequate
allocation concealment (where applicable), and
appropriate … Summary of evidence for key outcomes for pain management
following hip fracture
Outcome Comparison
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/pneumonia-antibiotic-treatment_executive.pdf
November 01, 2014 - Strength of evidence for using PK/PD measures to influence dosing or monitoring
Outcome
No. of Studies … We had no more than one study for any
included outcome, and this small number of studies had
small … Strength of evidence for comparisons of continuous and intermittent infusion
Outcome
Category Outcome … Category Outcome
No. of
Studies
(Subjects) Risk of Bias Consistency Directness Precision
Overall … While PK/PD dosing
strategies are supported by concept, the lack of prospective
patient outcome data
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/stroke-atrial-fibrillation_research-protocol.pdf
January 30, 2012 - strategies for resuming anticoagulation therapy following a hemorrhagic
event
• Patient-centered outcome … Diagnostic accuracy efficacy
Diagnostic thinking efficacy
Therapeutic efficacy
Patient outcome … o Diagnostic accuracy efficacy
o Diagnostic thinking efficacy
o Therapeutic efficacy
o Patient outcome … Grading the Evidence for Each Key Question
We will grade the strength of evidence for each outcome … and a summary
rating of “high,” “moderate,” or “low” strength of evidence will be assigned for each outcome
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/undescended-testicle_executive.pdf
December 01, 2012 - Neither study included
a clinically relevant outcome, so we did not assess the
strength of the evidence … We assessed the strength of evidence for our primary
outcome of testicular descent (Table E). … Strength of evidence of surgical treatments for cryptorchidism
Outcome Treatment
Number of Studies; … The most common
outcome assessed was testicular position; this is typically
the outcome targeted in … The primary outcome should
be successful placement of a normal-sized testicle in the
dependent portion
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-topic-refinement_methods.pdf
January 01, 2013 - They also emphasized that progression of stage may not always be a relevant
outcome. … Therefore, the refined topic did not include progression of stage as an explicit outcome
of interest … The outcome of one phase (e.g., Key Informant interviews) may lead to a revision in the
outcome of a … Formulate key
questions specific
to the outcome
categories
(patient-centered
outcome;
intermediate … outcome).
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/heart-failure-natriuretic-peptide_executive.pdf
November 01, 2013 - Prognosis
in which the outcome is associated with the concentration
of BNP/NT-proBNP is addressed in … The outcome of
hospitalization and the composite outcome of all-cause
mortality and cardiovascular … Mortality
All-cause mortality was the outcome in three studies,161-163
and in all three there was an … Future research is
likely to change
the magnitude and
direction of the effects
for the outcome of … Alpha-Defensins and
outcome in patients with chronic heart failure.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/disruptive-behavior-disorder_research-protocol.pdf
January 30, 2014 - on the study
characteristics, intervention(s), comparator(s), arm details, reported outcomes and
outcome … We will specifically assess for
detection bias by evaluating outcome measurement and assessment methods … We will record
strength of evidence assessments in tables, summarizing for each outcome. … When no studies are available for an outcome or comparison of
interest, we will grade the evidence as … Low We have limited confidence that the estimate of effect lies close to the true effect
for this outcome
-
effectivehealthcare.ahrq.gov/sites/default/files/fecal-incontinence_disposition-comments.pdf
March 21, 2016 - All of the outcome measures currently used to measure FI
have had limited patient input, including the … We added a statement
to the Discussion under Research Gaps:
Validated outcome measures that capture … TEP 2
Abstract Abstract: “Numerous outcome measures and lack of
compliance with study reporting … It is not an
outcome in itself. … The
Appendixes are also appreciated, especially the comments
regarding the outcome measures.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/insomnia_disposition-comments.pdf
December 30, 2015 - Affiliation Section Comment Response
Peer Reviewer 1 Introduction The PSQI is not an appropriate outcome … PSQI is NOT an appropriate or
specific measure of global outcome of insomnia treatments. … TEP Reviewer 6 Methods It appears that studies using only polysomnography to
evaluate outcome were not … Revised text: ‘Based on these factors, the overall
strength of evidence for each outcome was judged … Daytime functioning is an important outcome of
insomnia treatment and is captured in the instruments
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/delirium-research-protocol.pdf
June 01, 2018 - Data Synthesis – We will organize the report by Key Question and then by outcome. … If we see
substantial heterogeneity (I-squared > 50%) in pooled estimates for any outcome, we
will … Heterogeneity among the trials for each outcome we consider appropriate for
quantitative pooling will … .27 We will apply evidence
grades to the bodies of evidence about each comparison for each critical outcome … 5 outcomes that are most
11
important for each of the patient groups, with at least 1 outcome
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/worker-health_research-protocol.pdf
May 26, 2015 - This is a descriptive summary of interventions that are effective for
improving a health and safety outcome … or an intermediate outcome (from our
KQ 2 analysis). … Two reviewers will assess each domain for
each key outcome, and differences will be resolved by consensus … Low We have limited confidence that the estimate of effect lies close to the true effect for
this outcome … , we are unable to estimate an effect, or we have no confidence
in the estimate of effect for this outcome
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/hip-fracture-pain_research-protocol.pdf
December 09, 2009 - Pain medication use: change in type and quantity has been added as an
outcome.
ii. … We will classify the bodies of evidence pertaining to each primary outcome into
four basic categories … Functional outcome of cognitively
impaired hip fracture patients on a geriatric rehabilitation unit. … (block or analges*).mp.
5. or/2-4
6. exp Therapeutics/or exp "Outcome Assessment (Health Care)"/or … exp "Length of Stay"/or
"Quality of Life"/or "functional outcome".ti,ab.
7.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/asthma-nitric-oxide_research-protocol.pdf
September 06, 2016 - of severity)
KQ 1.e: Ages 0-4 years with recurrent wheezing episodes at the time of testing
but outcome … 2016
11
to assess sequence generation; allocation concealment; participant, personnel, and
outcome … assessor blinding; attrition bias; incomplete outcome data; selective outcome
reporting; and other … Grading the SOE will be done for each comparison and for each outcome. … We will produce summary of evidence tables that will provide
for each comparison and for each outcome
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/multiple-sclerosis_research-protocol.pdf
December 17, 2013 - relapse rates or, more importantly, disease
progression, currently lacks evidence, and so will not be an outcome … assessment,
incomplete outcome data, selective reporting, and other sources of bias (i.e., problems … risk of bias for this topic, likely including participant selection;
attrition, detection, selective outcome … We will develop items for both risk-of-bias instruments to assess selective outcome and
selective analysis … study limitations
(internal validity); (2) directness (single, direct link between intervention and outcome
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/diabetes-behavior-programs_research-protocol.pdf
June 05, 2014 - assessment, incomplete
outcome data, selective outcome reporting, and “other” sources of data), and … We will assess blinding
and incomplete outcome data separately for subjective outcomes (e.g., quality … For each outcome we will define a minimum clinically significant difference (MCSD; i.e., the
smallest … The minimum duration of 4 weeks does not include post-intervention
follow-up assessments for outcome … "Outcome Assessment (Health Care)"/
24. exp Patient Care Team/
25. exp Patient Compliance/
26.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/back-pain-treatment_clinician.pdf
November 01, 2016 - .
�� Across interventions, pain intensity was the most commonly
reported outcome, followed by back-specific … Summary of Key Findings and Strength of
Evidence for Interventions
Intervention Compared Intervention Outcome … Summary of Key Findings and Strength of Evidence for Interventions
Intervention Compared Intervention Outcome … Summary of Key Findings and Strength of Evidence for Interventions
Intervention Compared Intervention Outcome
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/depression-postpartum-screening_executive.pdf
May 01, 2013 - Strength of the Body of Evidence
We rated the strength of evidence for each KQ and
outcome using the … for test characteristics of screening tests
for postpartum depression (continued)
Screening
Test Outcome … The most
common relevant outcome was change in a screening
instrument depression score. … For studies of interventions,
common outcome measures are the highest priority. … • If a large part of the goal of screening for depression
is to improve longer term child outcome