-
effectivehealthcare.ahrq.gov/sites/default/files/bar-cohen_-eccs2012.pdf
January 01, 2012 - o Understand what the outcome is (getting disease, dying from
disease,
developing
a symptom), … o Understand the chance that you will experience the outcome.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/liver-cancer-therapy_research-protocol.pdf
November 28, 2012 - )
decided to limit the search to these dates to ensure the applicability of the interventions and
outcome … Assessment
o Identified primary outcome
o Identified secondary outcomes
o Follow-up frequency … o Were outcome measures clearly valid, reliable, and equally applied to treatment
groups? … o Were outcome assessors blinded?
o Was the length of followup adequate? … o Did the analysis of outcome data incorporate a method for handling confounders such
as statistical
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/cultural-competence_research-protocol.pdf
July 09, 2014 - assessment,
incomplete outcome data (i.e., was incomplete outcome data adequately addressed),
selective … Likewise, each of the outcome
categories listed here may be exploded for finer detail. … over time to assess
relationships with the outcome. … Who were outcome assessors?
9. … Are reports of the
study free of suggestion
of selective outcome
reporting?
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/acs-depression-research-protocol-amended.pdf
February 15, 2017 - The quality assessment will be outcome-specific such that a given study that analyzes
its primary outcome … well but did an incomplete analysis of a secondary outcome
would be assigned a different quality grade … We will
apply this outcome-specific quality assessment to groups of outcomes that have lower
risk of … We will grade the strength of evidence
for each selected outcome separately. … Outcome and impact of mental disorders in
primary care at 5 years.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/mental-illness-adults-prisons_research-protocol.pdf
September 13, 2012 - We will include the data when a smaller report provides data on an
outcome that was not provided by … For each included outcome, we will extract the
number of patients contributing data to each included … Was the outcome measure of interest objective
and was it objectively measured? … assessors
o If NOT blinded outcome assessors (or NR blinded outcome assessors), then
the outcome … o Was a nonblinded outcome assessor assessing a subjective outcome?
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/osteoarthritis-knee-update_research-protocol.pdf
June 15, 2016 - Measures in
Rheumatology) has developed guidelines on outcome measures.24
General tools that have … Studies of similar interventions will be grouped by outcome measures if
feasible. … However, if most studies that report on a common outcome report different
measures, we will conduct … Knee Injury and Osteoarthritis Outcome
Score (KOOS)--development of a self-
administered outcome measure … Predicting the outcome of total knee
arthroplasty.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/tonsillectomy_executive.pdf
January 01, 2017 - of interest
• Sufficiently detailed methods and results to enable data extraction (KQ1-6)
• Reports outcome … of the study population
(for applicability), description of the interventions, and
baseline and outcome … Few studies reported the same outcomes, and few reported
significant differences in any outcome between … Most studies used
subjective outcome measures or relied on caregiver- or
child-completed diaries to … Furthermore, most available studies provided little to
no long-term clinical outcome data, focusing
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/stroke-atrial-fibrillation_executive.pdf
August 01, 2013 - utility.39 Of note, a risk score may
have a statistically significant association with a clinical
outcome … to allow clinicians to accurately and reproducibly
separate patients who will and will not have the outcome … Strength of the Body of Evidence
We rated the strength of evidence for each KQ and
outcome using the … to major bleeding; 2
evaluated bleeding risk prediction scores with respect to
ICH as a separate outcome … A retrospective good-quality study of 53,778 patients
confirmed the stroke outcome findings.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/alcohol-misuse-drug-therapy_disposition-comments.pdf
May 13, 2014 - (and just the mental summary score of that
secondary outcome). … The Baser paper
did not report an eligible outcome. … We included this outcome in our review and we
found evidence on this outcome in many trials. … The primary outcome measure was event rate of heavy drinking. … Basically, the averages of the outcome (we used % subjects with no heavy
drinking outcome, same as FDA
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/blood-clots-hip-knee-surgery_disposition-comments.pdf
March 01, 2012 - Peer Reviewer #1 Methods Clarify if the outcome of "mortality" is "all-cause
mortality". … Peer Reviewer #1 Results 6.Page 120, distal DVT outcome, LMWH vs DTI
outcome, "included two separate … of any outcome events. … It is important as an outcome by itself. … versus
a "Final health outcome".
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/nonopioid-pharm-chronic-pain-protocol.pdf
February 01, 2019 - • Only validated outcome measures of
pain, overall function or disability, and
quality of life … points on the 0 to 24-point Roland-Morris Disability Questionnaire (RDQ), or equivalent; and for
any outcome … function as
a mean difference of 10 to 20 points on the ODI or 2 to 5 points on the RDQ, and for any
outcome … :
• High—We are very confident that the estimate of effect lies close to the true effect for
this outcome … • Low—We have limited confidence that the estimate of effect lies close to the true effect
for this outcome
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/type-2-diabetes-insulin_executive.pdf
September 01, 2008 - seen in the pooled odds ratios
for all-cause mortality, cardiovascular mortality, and the
combined outcome … findings on comparative effectiveness of
premixed insulin analogues and other antidiabetic agents
Outcome … findings on comparative effectiveness of
premixed insulin analogues and other antidiabetic agents
Outcome … comparative effectiveness of
premixed insulin analogues and other antidiabetic agents (continued)
Outcome … comparative effectiveness of
premixed insulin analogues and other antidiabetic agents (continued)
Outcome
-
effectivehealthcare.ahrq.gov/sites/default/files/ch_3-user-guide-to-ocer_130129.pdf
September 21, 2012 - While these designs
incorporate heterogeneity in the risk of outcome
among the subjects, they may also … exposure variables act in concert
to cause disease, we will observe that the effect
of exposure on outcome … may be required even
when the variable that modifies treatment effect is
not a risk factor for the outcome … Additionally, the different strength of association
between the exposure and outcome within strata of … This ensures some
degree of objectivity in the outcome modeling.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/ehc-depression-research-protocol.pdf
February 07, 2018 - measures, and the
results of each outcome, including measures of variability. … ) High – We are very confident that the estimate of effect lies close to the true effect
for this outcome … Low – We have limited confidence that the estimate of effect lies close to the true
effect for this outcome … are unable to estimate an effect, or we have
no confidence in the estimate of the effect for this outcome … or
excluding both-armed zero-event studies on using standard meta-analysis methods for
rare event outcome
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/plasma-cell-dyscrasias-sflc-assay_disposition-comments.pdf
August 23, 2012 - Definition criteria for
outcome measures are appropriated as are statistical
methods. … As stated above, the need for 24
hour urine collection could be considered as a relevant
outcome. … “Hospital stays” may be an unrealistic outcome to
measure for a laboratory test (would performing a … We have removed it from the list of
outcome measures; and indeed, we found no literature that
addressed … While elimination of the need for 24-hour urine collection
could well be considered an outcome for Key
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/coronary-artery-stenting_research-protocol.pdf
August 19, 2011 - The grading will be outcome specific such that a given study that analyzes its primary outcome
well … but did an incomplete analysis of a secondary outcome would be assigned a different quality
grade for … Impact of intravascular ultrasound-guided stenting on
long-term clinical outcome: a meta-analysis of … Does IVUS guidance of coronary interventions affect outcome? … 5/1/2012 Outcome
presentation of
Analytical
Framework,
Methods, and
Results section
Diagnostic
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0365_10-28-2010.pdf
January 01, 2010 - specific pharmacotherapies or
psychotherapies, in addition to wait list or placebo group participants
Outcome … characteristics (including those listed below) are associated with
variations in treatment response/outcome
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/autism-update_disposition-comments.pdf
August 06, 2014 - How do
you define the outcome? … How do you define
the outcome? … The
outcome that the intervention is targeting? … Outcome measures
appropriate.
Thank you for your comment. … We incorporated explicit assessments of outcome
measurement into our quality scoring systems.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/antiplatelet-treatment_disposition-comments.pdf
September 25, 2013 - We note, however, that selective
outcome reporting, publication bias, other biases, or
chance could … Definitions, outcome measures
and statistical methods are appropriate. … We agree that MACE represents an outcome of interest
for the tests evaluated in the report. … Teirstein
Results Platelet reactivity should be considered a viable surrogate
outcome measure. … Second they require that outcome definitions are shared
between studies and outcome ascertainment is
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/antipsychotics-children-future_research.pdf
February 01, 2012 - The limitations noted by the CER authors include
inadequate blinding of patients and outcome assessors … KQ 2
The extant literature is limited with regard to consistent and comparable outcomes and outcome … The extant literature lacks consistent and comparable outcomes and outcome
measurements across the … Exposure status is compared between
the two (or more) groups: those who have
the outcome of interest … and those who do
not have the outcome of interest
(controls).