-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/labor-nitrous-oxide_research-protocol.pdf
August 24, 2011 - measure of
an outcome listed in the PICOTS
Relevant outcomes must be extractable from data
presented … of interest, comparability of cohorts,
assessment of outcome, adequate duration of follow-up, and … Each key outcome on each comparison of interest will be given an overall
evidence grade based on the … When no studies are available for an outcome or comparison of
interest, the evidence will be graded … We will record strength of evidence
assessments in tables, summarizing for each outcome.
G.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/osteoporosis-bone-fracture_research-protocol.pdf
May 14, 2010 - • Outcomes
- The primary outcome is change in fracture incidence (vertebral, non-vertebral,
wrist … • Outcomes
- We propose using fracture incidence as the outcome. … , 6)
2º Outcome: Adverse
effects of treatment
Factors that affect
Adherence/persistence
with … In the report, evidence tables will be used to present this information, as well
as outcome data. … The data relevant to each outcome will be presented in individual tables.
-
effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/rt-bone-metatases-final-protocol-amendment.pdf
August 10, 2022 - For analysis of continuous measures across the
same outcome measures (e.g., VAS for pain) we will report … Based on this prioritized list, the strength of
evidence for comparison-outcome pairs within each KQ … will be initially assessed by one
researcher for each clinical outcome (see PICOTS) by using the approach … The aggregate
risk of bias across individual studies reporting an outcome is considered. … Low We have limited confidence that the estimate of effect lies close to the true effect
for this outcome
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/blood-clots-hip-knee-surgery_executive.pdf
March 01, 2012 - RCTs and observational studies included in KQ 10 and
KQ 11 needed to report on a prespecified outcome … Specific patient, intervention, comparator,
outcome, and setting factors that limit applicability were … KQ 3: Pulmonary embolism was the only final health
outcome with data depicting the relationship to the … intermediate outcome DVT. … Helps determine the
degree of importance of each variable for a given outcome.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/nonpharma-treatment-pain_research-protocol-amended.pdf
September 20, 2017 - In determining the strength of a body of evidence for each prioritized primary or
safety outcome, the … The aggregate risk of bias
across individual studies reporting an outcome is considered; graded as … • Precision: describes the level of certainty of the estimate of effect for a
particular outcome … Publication bias, selective
outcome reporting, and selective analysis reporting are types of reporting … • High—We are very confident that the estimate of effect lies close to the
true effect for this outcome
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0775-150722.pdf
May 12, 2015 - antipsychotic; all other
treatment options/variations (e.g., different dosage of the same
antipsychotic)
Outcome … treatment
options/variations (e.g., different dosage of the same non-
pharmacological treatment)
Outcome … Comparator(s): All other treatment options/variations (e.g., different dosage of the
same antipsychotic)
Outcome
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/omega-3-maternity_disposition-comments.pdf
October 12, 2016 - In
some cases different biomarkers were assessed in
different studies evaluating the same outcome; … Outcome measures and statistical methods
appropriate. … TEP Reviewer
#4
Methods Pediatric Outcome measures--cognitive
development:
The ones listed are … Prenatal DHA status and
neurological outcome in children at age 5.5 years are
positively associated … In the column labeled "Results," we
provided the name of the test (outcome
measure) as reported in
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/lumbar-fusion-protocol.pdf
June 20, 2024 - For analysis of continuous
measures across the same outcome measures (e.g., VAS for pain) we will report … Based on this prioritized list, the strength of evidence for
comparison-outcome pairs within each KQ … The aggregate risk of bias
across individual studies reporting an outcome is considered. … • Directness (direct or indirect)
o This is the degree to which the outcome is directly or indirectly … Prognostic factors for outcome following lumbar spine
fusion surgery: a systematic review and narrative
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/dietary-supplements_research-protocol.pdf
December 15, 2010 - dietary supplement constituents, quality, and
dosage makes it difficult to compare and predict the outcome … O: Outcome categories (please see below for details):
• Clinical outcomes (KQ 1)
• Intermediate … In addition to quantitative data for each outcome,
definitions, methods used to assess outcomes, and … timing of outcome measurement (such as
time from randomization) within each study will be extracted … eDefinition and methods used to assess outcome including timing, and comparability of assessment
across
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/tonsillectomy_research-protocol.pdf
February 10, 2016 - We revised the KQs and population, intervention, comparator, outcome, timing, and
setting … Population, intervention, comparator, outcome characteristics*
KQ Population Intervention … "[mh] OR therapy[tiab] OR
therapies[tiab] OR therapeutic[tiab] OR therapeutics[tiab] OR outcome … Intervention-outcome pairs will be given an overall evidence grade based on the ratings … When no studies are available for an outcome or comparison of interest, we
will grade
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/prostate-cancer-therapies-update_research-protocol.pdf
April 01, 2013 - Outcomes
• The primary outcome is overall mortality or survival. … Was the outcome measure of interest objective and
was it objectively measured? … o If outcome assessors were not blinded (item 3) or blinding of outcome assessors
was not reported, … then the outcome must have been objective (item 4). … o Not a blinded outcome assessor (item 3) and a subjective outcome (item 4)
• To be considered as having
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/fatty-acids-cardiovascular-disease_disposition-comments.pdf
August 12, 2016 - The definitions of the outcome measures could
be improved. … We have two
separate outcome sections
for these, MACE and CVD
death. … Otherwise, CVD,
per se, is not an outcome.
There is no standard
definition of MACE. … But
diabetes is not a CVD
outcome, nor was it
considered to be a standard
CVD intermediate outcome … BP was not a newly added
outcome.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/depression-brain-injury_executive.pdf
April 01, 2011 - of outcome by factors such as
severity are rare. … Association between psychiatric state and outcome following
traumatic brain injury. … Psychosocial
adjustment and employment outcome 2, 5 and 10 years after
TBI. … Head injury
as a predictor of psychological outcome in combat veterans. … Depression after
traumatic brain injury as a function of Glasgow Outcome
Score.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/thromboembolism-update-executive-170622.pdf
June 01, 2017 - Of note, almost all studies that reported serious adverse
events did not define the outcome. … Eight
had high risk of bias for selective outcome reporting. … However, as discussed, this outcome
is of unclear clinical importance. … Ideally, all existing RCTs should report their full set of
outcome results. … Studies mostly reported total DVT,
an outcome with unclear clinical significance.
-
effectivehealthcare.ahrq.gov/sites/default/files/thromboembolism-update-executive-170622.pdf
June 01, 2017 - Of note, almost all studies that reported serious adverse
events did not define the outcome. … Eight
had high risk of bias for selective outcome reporting. … However, as discussed, this outcome
is of unclear clinical importance. … Ideally, all existing RCTs should report their full set of
outcome results. … Studies mostly reported total DVT,
an outcome with unclear clinical significance.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs4-active-infection-rapid-response.pdf
May 01, 2024 - Am J Infect Control. 2020 48(6):633-637. – No outcome of interest
2. … Clin
Infect Dis. 2020 70(8):1613-1619. – No outcome of interest
28. … Infection. 50(6):1525-1533. –
No outcome of interest
34. … J Clin Microbiol. 2021 59(2). – No outcome of interest
44. … J
Hosp Infect. 2021 118:99-107. – No outcome of interest
50.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/hepatitis-c-treatment-future_research.pdf
April 01, 2013 - Outcome/Timing-Related Gaps:
1. … Any clinical
outcome
No evidence. Insufficient
Key Question 2a. … Outcome/Timing-Related Gaps:
1. … Note: HCV=hepatitis C virus, PICOT= Population, Intervention, Comparator, Outcome, and Timing. … Outcome of sustained virological responders
with histologically advanced chronic
hepatitis C.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/diverticulitis-research-protocol.pdf
January 01, 2019 - for each
outcome. … The questions will
be assessed for each outcome (e.g., whether each outcome was adjusted for potential … (primarily harms) reporting (for each outcome separately). … Outcome of patients with acute sigmoid diverticulitis:
multivariate analysis of risk factors for free … Diverticulitis in immunosuppressed patients: A
fatal outcome requiring a new approach?
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-202-thermoplasty-comments.pdf
December 14, 2017 - The degree of
improvement did not achieve the MID for
this outcome. … Most generally
consider exacerbations as a key outcome. … The primary outcome
for the trial was the quality of life scale,
AQLQ. … However,
the difference did not achieve the MID for
this outcome. … Why not just summarize each outcome
followed by findings with each study.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/fatty-acids-cardiovascular-disease_executive.pdf
August 01, 2016 - unclear regarding outcome assessor
blinding). … No outcome was
evaluated by more than two studies. … No outcome was reported in more than two
studies. … No outcome was evaluated by more than three studies. … No outcome was
evaluated by more than three studies.