-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/fatty-acids-cardiovascular-disease_clinician.pdf
July 01, 2017 - Omega-3 FA
[source] Outcome Key Findings
Net Change or RCT
Hazard Ratio (95% CI)
Number and
Type … insufficient to permit
conclusions about the effects of or associations between
DHA and any clinical outcome … permit
conclusions about the benefit of EPA or DPA, individually,
on any clinical or intermediate outcome … insufficient to permit conclusions about the
effects of or associations between ALA and any clinical
outcome … Omega-3 FA
[source] Outcome Key Findings
Net Change or RCT
Hazard Ratio (95% CI)
Number and
Type
-
effectivehealthcare.ahrq.gov/sites/default/files/protocol-social-isolation.pdf
January 01, 2013 - middle-income countries, skilled nursing facilities, assisted
living facilities, hospitals
Primary outcome … Primary studies will only be included if they report the primary
outcome. … including but not limited to depression,
quality of life, and chronic disease management)
Secondary outcome
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/rotator-cuff-tear-surveillance-140925.pdf
February 01, 2014 - Clinical
outcome in all-arthroscopic versus mini-
open rotator cuff repair in small to
medium-sized … Outcome
of rotator cuff repair in large-to-massive
tear with pseudoparalysis: a comparative
study … Functional outcome and
structural integrity following mini-open
repair of large and massive rotator … in all- 95 patients with full- All-arthroscopic versus Functional outcomes Functional outcome, pain, … Oh JH, et al.30 2011 Outcome of rotator
cuff repair in large-to-
massive tear with
pseudoparalysis:
-
effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/wic-outcomes-nutrition-protocol-amended.pdf
October 01, 2020 - • Studies that do not report a comparison
group KQ1-2 *
Outcomes All studies must evaluate an outcome … of
interest
Studies of barriers/facilitators related to
WIC participation but not linked to
outcome … The articles will not be excluded based on the study design and outcome at this level. … measures and the results of each outcome, including measures of variability. … Following this standard EPC approach, for each key outcome, we will assess the number of
studies, their
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/diabetes-behavior-programs_executive.pdf
September 11, 2015 - assessment, incomplete outcome data, selective outcome
reporting, and “other” sources of data) and … The assessment of high risk
was largely driven by incomplete outcome data (i.e., loss
to followup). … Flow diagram of study retrieval and selection
12
Outcome
Outcome
Timing
# Trials
(# Subjects … This
outcome may also benefit from in-person delivery rather
than incorporating technology. … Blinding of outcome assessors should always be attempted for subjective
outcomes.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-254-rural-telehealth-app-e.xlsx
January 01, 2021 - Were Outcome Assessors and/or Data Analysts Blinded or Are Primary Outcomes Unlikely To Be Biased (i.e … Outcome and Confounder Measures Reliable and Implemented Consistently Across Groups? … Outcome Assessors and/or Data Analysts Blinded or Are Primary Outcomes Unlikely To Be Biased (i.e. … Outcome Assessors and/or Data Analysts Blinded or Are Primary Outcomes Unlikely To Be Biased (i.e.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/tech-brief-31-mobile-applications-self-mgmt.pdf
May 01, 2018 - comparator
Outcome effect size
[95% CI] & P-value
Outcome
Measurement Details
Glucose Buddy … comparator
Outcome effect size
[95% CI] & P-value
Outcome
Measurement Details
Number: 63
Age … comparator
Outcome results Outcome
Measurement
Details
BlueStar
Diabetes
Quinn 20089
3 months … comparator
Outcome results Outcome
Measurement
Details
Gather Health
Kleinman 201614
6 months … comparator
Outcome results Outcome
Measurement
Details
Number: 100 ppts,
including 18 with type
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/indirect-comparisons_research.pdf
March 01, 2013 - Bayesian and Frequentist Model Comparisons for UI Pharmacological Treatments
With Outcome Continence … UI Data Interval Plot of Odds Ratios Between Drugs and Placebo for Each
Outcome .................... … Figure 1 exhibits the
network between drugs for each outcome. … Then if the event is a positive outcome we define the loss function
as Tk = Pk (and for negative outcome … In the discontinuation outcome,
tolterodine is the safest drug and oxybutynin performs worst.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/lung-cancer-nonsurgical-therapies_executive.pdf
June 01, 2013 - data for such patients:
– Survival outcome (overall survival or cancer-
specific survival)
– Local … data for such patients:
– Survival outcome (overall survival or cancer-
specific survival)
– Local … Failure to stratify or
disaggregate outcome data according to the treatment
Table A. … • OS is the primary direct outcome for any cancer intervention study. … Observation-only
management of early stage, medically inoperable lung cancer:
poor outcome.
-
effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/improved-cancer-outcomes-protocol_0.pdf
December 01, 2021 - bias: loss to follow-up, both overall and differentially between treatment groups
• Detection bias: outcome … assessor masking, outcome measurement quality
• Performance bias: intention to treat analysis, adjustment … data based on the conceptual clinical and methodological
heterogeneity (population, intervention, outcome … evidence, we will evaluate reporting bias by examining the potential for
publication bias, selective outcome … Based on these factors, the overall strength of evidence for each outcome will be rated as:
• High:
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-e-surv-report-3-noninvasive-nonpharma.xlsx
January 01, 2022 - Allocation Intention to Treat Analysis Baseline Group Similarity Patient Blinded Care Provider Blinded Outcome … Acceptable in All Groups Attrition Reported Attrition Acceptable Attrition B/w Groups Acceptable Timing of Outcome
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/phenylketonuria_research-protocol.pdf
March 29, 2011 - We will capture all
validated outcome measures available within these constructs and report on their … Each key outcome on each comparison of interest will be given an overall evidence grade
based on the … We will record
strength of evidence assessments in tables, summarizing for each outcome.
G. … , we changed the phrase to "cognitive impairment," which is a more targeted and measureable outcome. … We will record strength of evidence assessments in tables, summarizing for each outcome.
G.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/trauma-child-interventions_executive.pdf
February 01, 2013 - Population, intervention, comparator, outcome, timing, and setting (continued)
Domain Description
Outcome … Summary of Findings by Outcome
Table E presents detailed findings by outcome for
interventions with … Our outcome criteria also limited our review. … Another limitation of the evidence base results from
outcome assessment methods. … Outcome of
psychotherapy among early adolescents after trauma.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/insulin-blood-sugar_research.pdf
August 01, 2015 - Moreover, we
acknowledge that future studies should better study quality of life as an outcome. … Three Stakeholders ranked adherence as the highest priority outcome for future research in
children … two ranked severe hypoglycemia as highest priority outcome. … Among adults, three Stakeholders ranked severe hypoglycemia as the highest priority outcome;
and in … the elderly, all Stakeholders rated severe hypoglycemia as a high priority outcome in
future research
-
effectivehealthcare.ahrq.gov/sites/default/files/suppl-1-user-guide-to-ocer_130129.pdf
January 01, 2011 - and Choice
Actual
Outcome Y
Treatment
(T)
Treatment
Value
(T*)
P(Y) Y
Treatment
Choice
( … , and direct
effects on treatment valuation;
X
4
= factors having no direct effects on outcome, … but have direct effects on treatment valuation; and
X
5
= factors having direct effects on outcome, … Model of Treatment Choice and Outcome (adapted from Brooks
and Fang28)*
*This figure is copyrighted … Certain factors affecting
treatment choice have direct effects on outcome
(X
3
).
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/colorectal-surgery-preparation_research-protocol.pdf
March 26, 2013 - Quality of life
• Terminal clinical outcome
Source: http://effectivehealthcare.ahrq.gov
Posted: … Even if the
outcome rate is 10 percent (i.e., quite high), the sample size needs to be >400 patients … The grading will be outcome specific, such that
a given study that reports its primary outcome well … Furthermore, we expect that the completeness of outcome
definitions may be suboptimal. … each outcome of interest across
studies.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/acs-pci-adjunctive-devices_research-protocol.pdf
July 01, 2010 - criteria: comparable study groups at baseline,
detailed description of study outcomes, blinding of outcome … For each outcome, we
will conduct separate analyses of studies and compare each individual adjunctive … Risk of Bias
Risk of bias is the degree to which the included studies for any given outcome or
comparison … Precision refers to the degree of certainty surrounding an effect estimate with
respect to a given outcome … of the body of
evidence will then be determined and reported separately and qualitatively for each
outcome
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/suicidal-thoughts-young-people-amendement-may-2025.pdf
January 01, 2025 - psychiatric disorders, such as MDD, bipolar disorder, and substance
use disorders.8 There are diverse outcome … Clinical settings (e.g., outpatient, inpatient,
residential, emergency department)
• Timing of outcome … assessment (e.g., long-term
outcome assessment, short-term outcome
assessment)
• Social determinants … data, outcome measurement, selective reporting, and other sources of bias. … We will produce summary of evidence tables that will provide for each comparison and for each
outcome
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/cancer-ovarian-contraceptives_research-protocol.pdf
March 13, 2012 - Grading the Evidence for Each Key Question
The strength of evidence for each key question and outcome … For each outcome, we will use currently available estimates of lifetime
risk, prevalence of OC use, … and relative risk (or relative risk reduction) for that
outcome in OC users to generate estimates of … We will tentatively exclude any outcome from grading if the potential impact
of OC use was less than … The reference to
neurological conditions
(an outcome no longer
under consideration for
the systematic
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/abnormal-uterine-bleeding_research-protocol.pdf
November 21, 2011 - a clinically important difference (i.e.,
effect size) if such a difference exists for the primary outcome … measure for an outcome
listed in the PICOTS
Relevant outcomes must be extractable from data presented … Each key outcome on each comparison of
interest will be given an overall evidence grade based on the … We will record strength of evidence assessments in tables,
summarizing for each outcome.
G. … Clinical outcome of levonorgestrel intra-uterine
system in idiopathic menorrhagia.