-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-276-ocd-executive-summary.pdf
December 01, 2024 - effective than waitlist control for OCD symptoms (high SoE) and probably
more effective for remission outcome … location or medications other than SSRIs or clomipramine, we performed
separate network meta-analyses by outcome … For the most robust CY-BOCS outcome network, various control conditions, waitlist,
pill placebo, and … Given the relatively sparse evidence within comparator-outcome
categories, we did not perform subgroup
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/kidney-stones-protocol.pdf
September 24, 2024 - • Study Designs: RCTs; NRSI with concurrent comparator group and primary study
aim/outcome to assess … In some cases, we may report an outcome-specific ROB rating within a study if
we assess the outcome … If no studies are identified that report an outcome selected for SOE grading, we will grade the
outcome … Otherwise, we will assign an overall
SOE grade for each comparison and outcome as high, moderate, low … (s)
o Results
o Timing of measurement
o By relevant subgroups
• Secondary outcome(s)
o Results
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-g-surv-report-1-nonopioid-pharmacol-chronic-pain.xlsx
May 29, 2025 - Author, Year Randomization Adequate Allocation Concealment Adequate Patients and Personnel Masked Outcome
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/radiation-therapy-brain-metases-protocol.pdf
October 10, 2019 - data
• Detection bias and bias in measurement of the outcome
• Reporting bias and bias in selection … this knowledge could have influenced
the outcome measurement, and whether the outcome ascertainment … For the outcomes functional status and quality of life
we will assess whether the outcome assessment … The TEP also provided input on outcome measures within outcome domains (e.g.,
disease free survival … Outcome domains and individual outcome measures were selected for their
relevance and importance, and
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/autism_disposition-comments.pdf
November 01, 2010 - Instead, what has been
reported is wide variability in outcome within the
treated group. … Stating that pre-treatment features correlated with treatment
outcome is precisely true. … Statistically, this is a pre-treatment
by treatment group interaction predicting
outcome. … How
was "validity" of the outcome variable
determined? … The current lack of robust
and specific therapeutic outcome data is
adequately stated.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/infantile-hemangioma_executive.pdf
January 01, 2016 - Insufficient SOE for pain following PDL given low
numbers of outcome. … Insufficient SOE due to few instances of the outcome
reported in studies. … Insufficient SOE due to few instances of the outcome
reported in studies. … Insufficient SOE due to few instances of the outcome
reported in studies. … Studies differed in terms of study population
and outcome measures.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/vitamin-d-calcium_disposition-comments.pdf
September 15, 2014 - Since hip
fracture was a primary outcome in the WHI RCT
(whereas total fracture was a secondary outcome … and cancer, an
unplanned outcome. … ,
followed by sections that summarize studies of vitamin
D and calcium for each outcome. … Could the information be organized by outcome
instead? … of osteomalacia in addition to the
childhood vitamin D deficiency outcome of rickets.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/grades-predictive-values_white-paper.pdf
September 01, 2015 - Low We have limited confidence that the estimate of effect
lies close to the true effect for this outcome … we are unable to estimate an
effect, or we have no confidence in the estimate of effect
for this outcome … reliably predict that future studies will
have a minor impact on the estimate of effect of a given outcome … will have a substantial impact
on the direction or magnitude of the estimate of effect of a given outcome … Outcome
Bone mineral density % change: hip
Minimal important difference (MID): Authors provide no
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/diabetes-update-2015_research-protocol.pdf
January 01, 2015 - ^ We will not evaluate this outcome for metformin vs. sulfonylurea comparisons as the evidence was … § We will evaluate this outcome only for comparisons that include a SGLT-2 inhibitor. … Heterogeneity among the trials for each outcome we consider appropriate for quantitative
pooling will … For the outcome of hypoglycemia, we will conduct separate analyses for: (a) severe
hypoglycemia and … , long-term outcome, and for hypoglycemia.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/antidepressants-update_executive.pdf
December 01, 2011 - studies that had large sample
sizes (1,000 patients or more), lasted at least 3 months,
and reported an outcome … The strength of evidence for each outcome or
comparison that we graded incorporates scores on four
domains … excluded:
7 Foreign languages
10 Too short of duration
84 Wrong population
142 Wrong drug
197 Wrong outcome … of Life
Quality of life or functional capacity was infrequently
assessed, usually as a secondary outcome … Question 1b: Greater
efficacy and effectiveness with previously effective medications
Disorder, and Outcome
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/opioid-treatments-chronic-pain-protocol.pdf
December 19, 2018 - PICOTS
Key
Question
Population Intervention Comparator Outcome
1a, b Adults (age ≥18
years) with … life, doses of
opioids used
8
Key
Question
Population Intervention Comparator Outcome … life; doses of
opioids used
9
Key
Question
Population Intervention Comparator Outcome … Treatment Outcome/
34. … (treatment and (outcome or strateg$ or plan$)).ti,ab,kf.
35. 32 and (33 or 34)
36. limit 35 to yr
-
effectivehealthcare.ahrq.gov/sites/default/files/ch_5-user-guide-to-ocer_130129.pdf
January 01, 2012 - The existence and
magnitude of confounding for any given pair of
treatments and outcome is directly … For example, consider an epidemiologic study of
the effect of treatment A (exposed) on outcome Y. … It is common
that information about the patient, exposure or
comparison treatment, and/or outcome is … Coronary
angioplasty volume-outcome relationships for
hospitals and cardiologists. JAMA. … Association of volume with outcome of
coronary artery bypass graft surgery.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/opioid-chronic-pain-surveillance-report-3.pdf
June 01, 2022 - Treatment Outcome/
34. … Treatment Outcome/
34. … Exclusion reason: Ineligible outcome
174. … Exclusion reason: Ineligible
outcome
224. … Exclusion reason: Ineligible
outcome
299. Uebelacker La VNDTGBGAASM.
-
effectivehealthcare.ahrq.gov/sites/default/files/s89.pdf
October 01, 2007 - For the purposes of evaluating our surveil-
lance system and testing outcome definitions for future vac … For each
outcome, we calculated a 42-day incidence rate and multi-
plied this by the number of MCVs actually … After Meningococcal Conjugate Vaccination, Vaccine Safety Datalink Project Health Plans, 2005–2007
Outcome … Meningococcal
Vaccinations in the
Analysis for This
Outcome*
Cumulative No. … Meningococcal
Vaccinations in the
Analysis for This
Outcome*
Cumulative No.
-
effectivehealthcare.ahrq.gov/sites/default/files/s50.pdf
October 01, 2007 - about compar-
ative effectiveness of treatments is to collect comprehensive
patient, treatment, and outcome … variables Powered for primary outcome Many outcomes assessed
Change based on evidence Improvement based … measures
Variables specified precisely for all patient,
treatment, and outcome measures
Database Limited … knowledge; entails participation
by practicing clinicians
Confounders Assumed not relevant to study or outcome … Outcome Factors
Commonly assessed outcomes include condition-spe-
cific complications, condition-specific
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/undescended-testicle_research-protocol.pdf
September 02, 2011 - measure of an
outcome listed in the PICOTS
Relevant outcomes must be extractable from data presented … domains will include: adequate sequence
generation, allocation concealment, blinding, incomplete outcome … Each key outcome on each comparison of interest will be given an overall
evidence grade based on the … When no studies are available for an outcome or comparison of
interest, the evidence will be graded … We will record strength of evidence
assessments in tables, summarizing for each outcome.
13
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0129_07-13-2009.pdf
January 01, 2009 - status;
geographic region
Comparator(s): non-use of interventions listed above, “standard” care
Outcome … various factors,
interventions, and practices that include cesarean rate as a primary or secondary outcome
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0587-131115.pdf
March 06, 2013 - and management of NMIBC
Comparator(s): Various new and existing therapies and diagnostic approaches
Outcome … characteristics (stage, grade, multiplicity, size, molecular and genetic
alterations) predict oncologic outcome
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/kidney-stones-draft-appendi-c.xlsx
January 01, 2024 - Was classification of intervention status influenced by knowledge of the outcome or risk of the outcome … or a cause of the outcome? … Were complete data on the outcome available for all, or nearly all, participants? … ) likely to be related to the true value of the outcome? … measurements (e.g., scales, definitions, time points) within the outcome domain?
-
effectivehealthcare.ahrq.gov/sites/default/files/llewellyn-thomas.pdf
January 01, 2011 - Process and
outcome criteria for “good” V/P
elicitation.
• E. Conclusion. … o outcome levels of information comprehension or anxiety? … • Or are other process/outcome criteria of greater importance when investigating dynamic
phenomena … COMPARATIVE CRITERIA:
• Operational criteria
• Cognitive psychology criteria
Slide
39: SOME OUTCOME … assumptions.
• Raised research issues inherent in these different approaches.
• Suggested process and outcome