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Total Results: 2,153 records

Showing results for "outcome".

1721. Calcineurin_Inhibitors_Protocol_FINAL_10-07-2014 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/calcineurin-inhibitor_research-protocol.pdf
      October 08, 2014 - was not provided by the largest report or reports longer follow-up data for an outcome. 3. … This rating is made separately for each outcome of each comparison of each KQ. … A refined method for the meta-analysis of controlled clinical trials with binary outcome. … Was the outcome measure of interest objective and was it objectively measured? 18. … Was a standard instrument used to measure the outcome? 19.

1722. Disposition of Comments for CER 175 Total Worker Health (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/worker-health_disposition-comments.pdf
      May 31, 2016 - I would suggest adding a decrease in physical inactivity as an intermediate outcome, independent of … We note that “frequency of physical activity” is an included outcome and consider this to include … For example to determine the added value of the TWH approach for a specific outcome, such as smoking … Peer Reviewer #1 Methods Methods and outcome measures are appropriate. Thank you. … Our categorization of outcomes as “intermediate” and “health outcome” also addresses this issue; in

1723. Cancer-Ovarian-Contraceptives Executive (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-ovarian-contraceptives_executive.pdf
      June 01, 2013 - with inadequate sample size Publications • English-language only • Peer-reviewed articles • Outcome … reporting falls within the following publication ranges: – Study reports an ovarian cancer outcome … dWe considered studies published from January 2000 to June 2012 for the primary, ovarian cancer, outcome … Our general approach for each outcome was to analyze, if possible, the following associations: (1) … Differences in formulations, in prevalence of genetic and acquired factors affecting outcome risk,

1724. Evidence Report on the (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/patient-centered-medical-home_research-protocol.pdf
      February 23, 2012 - PICOTS (Population, Intervention, Comparator, Outcome, Timing, Setting) Framework for the Key Questions …  For KQ 1-3, a study must report a relevant outcome. … These general criteria will be customized to each major outcome. … Grading the Evidence for Each Key Question Grading the strength of evidence will be outcome-specific … In brief, this method uses the PICOTS (Population, Intervention, Comparator, Outcome, Timing, Setting

1725. Interventions Targeting Sensory Challenges in Children With Autism Spectrum Disorders - An Update (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/asd-interventions-disposition.pdf
      May 26, 2017 - TEP Reviewer #1 Methods The definitions of outcome measures described risk of bias assessment of … The the range of outcome variables studied is also extensive and comprehensive. … The the range of outcome variables studied is also extensive and comprehensive. … We re-examined the data for these studies and determined that the outcome measures were too disparate … We re-examined the data for these studies and determined that the outcome measures were too disparate

1726. Dementia-Agitation-Aggression Research-Protocol (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/dementia-agitation-aggression_research-protocol.pdf
      November 13, 2014 - assessment, incomplete outcome data (i.e., was incomplete outcome data adequately addressed), selective … Outcome Source: www.effectivehealthcare.ahrq.gov Published online: November 13, 2014 12 measurement … the results in evidence tables and synthesize evidence for each unique population, comparison, and outcome … (1) study limitations (risk of bias); (2) directness (single, direct link between intervention and outcome … Based on these factors, the overall strength of evidence for each outcome will be rated as:41 • High

1727. CER 173 Executive Summary: Diabetes Medications for Adults With Type 2 Diabetes: An Update (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/diabetes-update-2015_executive.pdf
      January 01, 2015 - *Not every outcome was assessed for each comparison. … After excluding studies that no longer had a comparison or an outcome of interest and cohort studies … No trial specified mortality or a macrovascular or microvascular outcome as its primary outcome. … Most of the evidence on subgroups was for the outcome of HbA1c and did not show differential effects … in Patients with Type 2 Diabetes (CAROLINA) and the Cardiovascular and Renal Microvascular Outcome

1728. Topic 0586 LUTS Secondary to BPH NSD FINAL (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0713-140625.pdf
      January 07, 2014 - treatment, placebo, lifestyle changes, other pharmacological treatments, and all other treatment options Outcome … nocturia (e.g., diabetes, heart failure) Comparator(s): All other diagnostic techniques and strategies Outcome

1729. Disposition of Comments Report for Childhood Obesity Prevention Programs: A Comparative Effectiveness Review and Meta-Analysis (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/obesity-child_disposition-comments.pdf
      June 10, 2013 - Or is one outcome selected, and if so, based on what hierarchy? … We did not have separate key questions for intermediate outcome and clinical outcomes. … ” vs. what other outcome? … which makes it possible to quickly find the outcome of interest. … Cost was not reported as an outcome in any of the studies we included in this review.

1730. Venous-Ulcers-Treatment-Future Research (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/venous-ulcers-treatment-future_research.pdf
      January 01, 2014 - • Outcome: Important outcomes include the rate of ulcer healing, and recurrence rate. … • Outcome: Important outcomes include the rate of ulcer healing, and recurrence rate. … • Outcome: Important outcomes include the rate of ulcer healing, and recurrence rate. … • Outcome: Important outcomes include the rate of ulcer healing, and recurrence rate. … Gottrup F, Apelqvist J, Price P; European Wound Management Association Patient Outcome Group.

1731. Layout 1 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/gerd_executive.pdf
      September 01, 2011 - They provided information on study design, patient and intervention characteristics, outcome definitions … (0 to 64 percent in 3 out of 7 studies reporting outcome). … Factors that influenced the outcome of Moderate • Six RCTs comparing different PPIs, or dosages and … Factors that influenced the outcome of Low • One RCT found that preoperative esophageal motility did … Factors that influenced the outcome of Low • Three cohort studies examined different modifying factors

1732. Long-Term Drug Therapy and Drug Holidays for Osteoporotic Fracture Prevention (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/research-protocol-osteoporosis_2.pdf
      October 05, 2018 - or a safety outcome … ) • Harms (Serious adverse events and specific harms as listed in Table 2) Outcome predictors ( … Data Synthesis Results will be organized first by treatment comparison and then by treatment outcome … Based on these elements, we will assess the overall strength of evidence for each comparison and outcome … If strength of evidence for a treatment- outcome comparison is rated insufficient based on assessment

1733. Evidence Report on the (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/vte-protocol-8-4-10.pdf
      February 01, 2008 - Ideally a surrogate marker would be correlated with a final outcome and demonstrate that an intervention … impacting the surrogate marker also predicts the effect on the clinical outcome of interest.5,6 In … thrombin inhibitors) to mechanical interventions; and 3) report data on at least one pre- specified outcome … definition, and diagnostic test used to confirm outcome of interest. … We will conduct meta-analyses when 2 or more studies adequate for pooling are available for any outcome

1734. Evidence Report on the (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/blood-clots-hip-knee-surgery_research-protocol.pdf
      February 01, 2008 - Ideally a surrogate marker would be correlated with a final outcome and demonstrate that an intervention … impacting the surrogate marker also predicts the effect on the clinical outcome of interest.5,6 In … thrombin inhibitors) to mechanical interventions; and 3) report data on at least one pre- specified outcome … definition, and diagnostic test used to confirm outcome of interest. … We will conduct meta-analyses when 2 or more studies adequate for pooling are available for any outcome

1735. Disposition of Comments for Chronic Urinary Retention: Comparative Effectiveness and Harms of Treatments (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/chronic-urinary-retention_disposition-comments.pdf
      September 15, 2014 - Author please clarify such allocation - outcome measures: Regarading primary outcomes PVR was not … included but in the second group 2 of the studies included considered PVR as a primary outcome. … PVR was not considered a primary outcome because it is not patient-centered. … intermediate outcome. … The definitions and diagnostic criteria for outcome measures are appropriate.

1736. breast-biopsy-update-130920 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/breast-biopsy-update_research-protocol.pdf
      September 20, 2013 - The grading will be outcome specific, such that a given study that reports its primary outcome well … but did an incomplete analysis of a secondary outcome would be graded as having different quality for … Of note, the material used to solicit TEP input will not include any data on outcome results extracted … “not suspected”) will be evaluated with respect to publication bias, selective outcome reporting bias … each outcome of interest across studies.

1737. Colorectal-Surgery-Preparation Executive (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/colorectal-surgery-preparation_executive.pdf
      April 01, 2014 - We did pairwise meta-analyses for outcome comparisons with more than three nonoverlapping studies. … Separate analyses by anatomic location were possible only for the outcome of anastomotic leakage. … (This is why the number of studies for each outcome in Table A is not 18.) 8 Table B. … When two or more studies provided information for the same outcome, no conclusions could be reached … We did not attempt a meta-analysis because of the substantial diversity in outcome definitions, and

1738. Disposition of Comments Report for Antiplatelet and Anticoagulant Treatments for Unstable Angina/Non-ST Elevation Myocardial Infarction (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/angina-heart-attack-treatments_disposition-comments.pdf
      January 01, 2014 - Peer Reviewer 5 Methods definitions, search strategies, and outcome measures all explicitly presented … I couldn’t find an indication that outcome definitions were assessed for rigidity or consistency (MI … We refer the reader to the explanation in the text and the detailed SOE table where this outcome was … 30kg/m2: Composite outcome (vascular death, nonfatal MI, or stroke at 30 days 1 year) Major bleeding … be data for each outcome of interest.

1739. Layout 1 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/juvenile-arthritis-dmards_executive.pdf
      September 01, 2011 - The outcome measures assessed were: • Measures of disease activity: - Active joint count (AJC) - Physician … One particularly important challenge is the development of outcome measure tools that fully describe … • Variation in outcome measures. … Outcome measures vary across the studies and are sometimes incompletely described. … In addition, focusing on the most responsive outcome measures to assess treatment effects would enhance

1740. Computerized Definitions Showed High Positive Predictive Values for Identifying Reasons for Hospitalizations in a Medicaid Population with Rheumatoid Arthritis (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/rheumatoid-arthritis-hospitalizations_research.pdf
      October 01, 2008 - Inter-reviewer agreement was at least 77% for any outcome. … Although time and resource consuming, evaluating the accuracy of outcome identification is often necessary … Therefore, we restricted our evaluation of this outcome to primary diagnoses. … Use of predictive value to adjust relative risk estimates biased by misclassification of outcome status … ICD9-CM Codes Used in Computerized Definitions Outcome ICD9-CM Rheumatoid arthritis 714.0, 714.1