-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/breastfeeding-health-outcomes-disposition-comments.pdf
March 31, 2025 - with this outcome, it was not
included. … We
noted the exclusion of this outcome in the Limitations
of our Review Methods. … health outcome for human
milk feeing – dental caries. … We did not include the Gungor review for this
outcome because the included, more recent reviews
by … leading to outcome assessment bias.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/autism-medical-update_research-protocol.pdf
February 16, 2016 - Outcomes
We will address the following broad outcome categories. … We will assess the risk of bias based upon the study-defined primary outcome(s). … No confidence in the estimate of effect for this
outcome. … Young Adult Outcome of Autism Spectrum Disorders. … Adult outcome for children with autism. J Child
Psychol Psychiatry 2004 Feb;45(2):212-29.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/long-term-care-adults-future_research.pdf
July 01, 2013 - Evidence was insufficient for other outcome domains
and comparisons. … Stakeholders also indicated that
finding standardized outcome measures is an important priority. … Because
individuals within an LTC setting are at different points on an outcome trajectory, it can … Evidence was insufficient for other outcome domains
and comparisons. … Stakeholders emphasized the importance of finding
standardized outcome measures.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/carbohydrate-intake-protocol.pdf
April 08, 2024 - Inclusion and Exclusion Criteria by Population, Intervention, Comparator,
Outcome, Timing, Setting/Study … Outcome KQ1:
Newborn size and body
composition
• Birth weight, weight-
for-age and percentile … The aggregate risk of bias across
individual studies reporting an outcome is considered. … • Directness (direct or indirect)
o This is the degree to which the outcome is directly or indirectly … Low Limited confidence that the estimate of effect lies close to the true effect
for this outcome.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0430_04-22-2011.pdf
January 01, 2011 - cystoscopy, x-ray, computed tomography scan, prostate-specific
antigen measurement, urodynamic tests)
Outcome … Different catheter types, use of adjuvant pharmacologic agent, different
catheter management policies
Outcome … agents
Comparator(s): Comparison between individual interventions or combinations of
interventions
Outcome
-
effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/pdf/child-growth-development-outcomes-protocol.pdf
August 19, 2024 - Inclusion and Exclusion Criteria by Population, Intervention, Comparator,
Outcome, Timing, Setting/Study … Based on this prioritized list, the SOE for exposure/intervention-outcome pairs
within each KQ will … The aggregate risk of bias
across individual studies reporting an outcome is considered. … • Directness (direct or indirect)
o This is the degree to which the outcome is directly or indirectly … Low Limited confidence that the estimate of effect lies close to the true effect
for this outcome.
-
effectivehealthcare.ahrq.gov/sites/default/files/s13.pdf
October 01, 2007 - may be sus-
ceptible to systematic error, including selection bias, exposure
misclassification, and outcome … possibility of effect modification, which occurs when the
association between the exposure and the outcome … Outcome misclassification is also a substantial threat to
the validity of the study. … Sometimes this could result in mis-
classification of outcome. … This indication is
commonly associated with the outcome under study, so
unless the indication can be
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ced-topic-refinement.pdf
November 01, 2022 - F Outcome(s) The key outcome(s) for study are those that are clinically
important to patients and durable … The key outcome(s) for the
study are those that are
important to patients. … The primary outcome(s) for the
study are clinically meaningful
and important to patients. … The key outcome(s) for the study are those that are important to
patients. … The key outcome(s) for the study are those that
are important to patients.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/peripheral-nerve-block-protocol.pdf
November 18, 2023 - We agree this likely will be rarely reported, but we will attempt to identify
outcome correlations … ● Outcome: Comments on outcomes highlighted a need for defining efficacy and
narrowing the scope … Overall risk of bias assessments for each study outcome will be classified as low, moderate,
or high … Data Synthesis
Results will be organized by intervention comparison, targeted outcome, and outcome … For each comparison, one review author will rate the certainty of evidence
for each outcome as high
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ced-appendix-3.xlsx
June 24, 2022 - when there is need for greater certainty around the temporal relationship between the exposure and outcome … CMS Design_bias Address Differential assessment of outcome (detection bias). … variables to minimize outcome misclassification. … CMS Design_bias Address Differential assessment of outcome (detection bias). … variables to minimize outcome misclassification.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-e-opioid-chronic-pain-surveill-report-1.xlsx
January 01, 2021 - Outcome Assessors Masked? Care Provider Masked? Patient Masked? … Were Outcome Assessors and/or Data Analysts Blinded to the Exposure Being Studied?
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/administrative-data-validity_research.pdf
January 01, 2007 - Measure the positive predictive value of a specific outcome that might be employed in studies of comparative … In particular, we validated hospitalization for the composite outcome of sudden
cardiac death and ventricular … VF and VT), some authors prefer the term “presumed
arrhythmic death” to SCD.14 Validation of this outcome … This potentially argues that studies of utilizing this outcome should
include only those SCD/VA events … Conclusion: Overall, our outpatient-occurring composite SCD/VA outcome validated poorly (PPV= 18%).
-
effectivehealthcare.ahrq.gov/sites/default/files/upenn-final-report-2005-certs-ce-supplement.pdf
January 01, 2005 - Measure the positive predictive value of a specific outcome that might be employed in studies of comparative … In particular, we validated hospitalization for the composite outcome of sudden
cardiac death and ventricular … VF and VT), some authors prefer the term “presumed
arrhythmic death” to SCD.14 Validation of this outcome … This potentially argues that studies of utilizing this outcome should
include only those SCD/VA events … Conclusion: Overall, our outpatient-occurring composite SCD/VA outcome validated poorly (PPV= 18%).
-
effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/hypertensive-disorders-pregnancy-protocol-amendment.pdf
April 20, 2022 - Questions related to outcome assessor blinding, missing data, outcome measurement
reporting adequacy … , and analytic adequacy will be assessed for each outcome. … measurement, analysis plan).28 The questions
will be assessed for each outcome (e.g., whether each … outcome was adjusted for potential
confounders). … Patient-reported outcome measures and patient-reported experience
measures.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/type-2-diabetes-medications-update_executive.pdf
March 01, 2011 - We noted
that one medication or class may have favorable effects
on one lipid outcome and unfavorable … effects on
another lipid outcome. … We
did not identify any studies for the outcome of
retinopathy. … Insufficient No studies addressed the outcome of retinopathy. … Cancer Insufficient Few studies addressed the outcome of cancer.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/fecal-incontinence_research-protocol.pdf
November 30, 2014 - assessment, incomplete outcome data, selective
outcome reporting, and other sources of bias (i.e., … Outcome measures for fecal
incontinence: anorectal structure and function. … Were important
variables known to
impact the outcome(s)
assessed at baseline? … Are statistical
methods used to assess
the primary outcome
appropriate to the data? … Is there suggestion
of selective outcome
reporting?
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-bias_methods.pdf
February 01, 2013 - The outcome measures included, and inclusion of non-English
language papers account for at least some … Our analysis of these reviews focused on the prevention of stress ulcer bleeding,
as this outcome was … Outcome
Described as
effectiveness
outcomes
Reviewers determine whether
specific outcomes are … Lack of specificity on other aspects of outcome measurement may also bias SR conclusions. … Selective Outcome Reporting as a Source of
Bias in Reviews of Comparative
Effectiveness.
-
effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/missing-data-registries-guide-3rd-ed-addendum-white-paper.pdf
February 01, 2018 - other factors) and therefore the outcome is
inexplicitly linked to the missing data. … (Prepared by the Outcome
DEcIDE Center [Outcome Sciences, Inc., a
Quintiles company] under Contract … (Prepared by the Outcome DEcIDE Center
[Outcome Sciences, Inc., a Quintiles
company] under Contract … (Prepared by the Outcome
DEcIDE Center [Outcome Sciences, Inc., a
Quintiles company] under Contract … Long-term outcome after acute kidney
injury in critically-ill patients.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/juvenile-arthritis-dmards_surveillance.pdf
March 14, 2013 - possibly out of date
- The conclusions for KQ4 (DMARDs and various
categories of JIA) and KQ5 (outcome … Evidence Table
Author, year Trial n Subjects Primary Outcome Duration Findings
Key Question 1: In … Author, year Trial n Subjects Primary Outcome Duration Findings
Quartier, 201121 RCT, anakinra vs … Author, year Trial n Subjects Primary Outcome Duration Findings
No new evidence No new evidence No … Author, year Trial n Subjects Primary Outcome Duration Findings
Wallace, 201128 RCT of
etanercept+
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/juvenile-arthritis-dmards_surveillance.pdf
March 14, 2013 - possibly out of date
- The conclusions for KQ4 (DMARDs and various
categories of JIA) and KQ5 (outcome … Evidence Table
Author, year Trial n Subjects Primary Outcome Duration Findings
Key Question 1: In … Author, year Trial n Subjects Primary Outcome Duration Findings
Quartier, 201121 RCT, anakinra vs … Author, year Trial n Subjects Primary Outcome Duration Findings
No new evidence No new evidence No … Author, year Trial n Subjects Primary Outcome Duration Findings
Wallace, 201128 RCT of
etanercept+