Results

Total Results: 2,968 records

Showing results for "outcome".

121. Ch 9-User-Guide-To-Ocer 130129 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/ch_9-user-guide-to-ocer_130129.pdf
     September 21, 2012 - Most importantly, investigators must specify a primary study outcome and a minimum treatment effect … of interest for that outcome. … In trials with a continuous outcome (e.g., LDL cholesterol), investigators must make assumptions about … the standard deviation of the outcome in each trial arm; when the outcome is the occurrence of an … Describe: - The primary outcome on which the study size or power estimate is based.

122. Strategies To Reduce Cesarean | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/cesarean-birth-2010/research-protocol
     May 06, 2011 - in two and as a secondary outcome in four others. … Additional nonrandomized controlled trials that had cesarean rate as a primary or secondary outcome ( … We will capture all relevant outcome measures available and report them as part of the data extraction … Each key outcome on each comparison of interest will be given an overall evidence grade based on the … We will record strength of evidence assessments in tables, summarizing for each outcome. G.

123. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/cesarean-birth-2010_research-protocol.pdf
     January 01, 2010 - in two and as a secondary outcome in four others. … Additional nonrandomized controlled trials that had cesarean rate as a primary or secondary outcome … Abbreviations: PICOTS = population, intervention, comparator, outcome, timing, and setting. … of interest, comparability of cohorts, assessment of outcome, adequate duration of followup, and … We will record strength of evidence assessments in tables, summarizing for each outcome. G.

124. Expanded Guidance on Selected Quantitative Synthesis Topics | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/quantitative-synthesis-expanded-methods/methods
     March 13, 2013 - Combining Composite Outcomes A composite outcome can be binary (0/1) or time-to-event. … Although the use of a composite outcome as the primary outcome in a clinical trial can reduce sample … Interpretation of composite outcome results is fraught. … Criteria for selecting outcomes for combining Outcome definitions Specify whether outcome definitions … This should be done for each outcome considered.

125. Ch 4-User-Guide-To-Ocer 130129 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/ch_4-user-guide-to-ocer_130129.pdf
     January 01, 2010 - First, it is helpful to lay out a theoretical link between the exposure and the event/outcome of interest … because all of the exposure necessary to cause the event or outcome has been completed. … The latent period is the time from when the outcome starts to when the outcome is identified. … In other words, it is the period between when the disease or outcome begins and when the outcome is … of Outcome interest complete Identi�ed/Diagnosed Start of outcome x x x xx x xxx xxx

126. Breast Reconstruction After Mastectomy | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/breast-reconstruction-mastectomy/protocol
     June 18, 2020 - assessors, and subjective outcome assessors; incomplete outcome data; selective outcome reporting; and … assessors, and subjective outcome assessors; incomplete outcome data; selective outcome reporting; and … data, selective outcome reporting, and other issues that could be related bias. … Development of a core outcome set for research and audit studies in reconstructive breast surgery. … Developing core outcome sets for clinical trials: issues to consider.

127. ASSESSING THE QUALITY OF INCLUDED STUDIES (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/assessing-the-risk-of-bias_draft-report.pdf
     June 02, 2011 - Blinding of outcome assessors, especially with subjective outcome assessments, bias in inferential … reporting for another outcome. … Alternatively, with no evidence of selective outcome reporting for an individual outcome, EPCs may … still judge that selective outcome reporting exists for the body of evidence for that outcome alone … of the outcome data in studies reporting that outcome. 9 This overall risk-of-bias is dictated by

128. Pharma-Nonpharma-Ptsd-2022-Update-App-G2-3 (xls file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/pharma-nonpharma-ptsd-2022-update-app-g2-3.xlsx
     January 01, 2022 - Outcome Data (Cochrane) or Attrition Bias (AHRQ); Attrition Bias Due to Missing Outcome Data (Cochrane … Measurement Risk of Bias in Measurement of the Outcome (Cochrane) or Detection Bias (AHRQ); Outcome … Risk of Bias in Measurement of the Outcome (Cochrane) or Detection Bias (AHRQ); Outcome Measurement … Risk of Bias in Measurement of the Outcome (Cochrane) or Detection Bias (AHRQ); Outcome Measurement Risk … of Bias in Measurement of the Outcome (Cochrane) or Detection Bias (AHRQ); Outcome Measurement: RoB

129. Methods Guide for Comparative Effectiveness Reviews - Expanded Guidance on Selected Quantitative Synthesis Topics (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/quantitative-synthesis-expanded-methods_methods.pdf
     March 01, 2013 - If a composite outcome is time-to-event, it takes the value of the time until the first event. … Although the use of a composite outcome as the primary outcome in a clinical trial can reduce sample … • Interpretation of composite outcome results is fraught. … Criteria for selecting outcomes for combining Outcome definitions Specify whether outcome definitions … This should be done for each outcome considered.

130. Trauma Informed Care (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/trauma-informed-care-protocol.pdf
     April 19, 2023 - Population, intervention, comparator, outcome, timing, setting (PICOTS) PICOTS KQ1 KQ2 Population … blinding (performance and detection bias), completeness of follow-up (attrition bias), analyses and outcome … Overall risk of bias assessments for each study-outcome will be classified as low, high, or unclear … Based on these factors, the overall strength of evidence for each intervention/comparator/ outcome will … Childhood maltreatment predicts unfavorable course of illness and treatment outcome in depression: a

131. Topic 0590 Strategies to Treat and Manage Infantile Hemangioma NSD FINAL_SJ (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0715-140408.pdf
     April 08, 2014 - Children with infantile hemangiomas Intervention(s): Early referral Comparator(s): Delayed referral Outcome … resonance imaging (MRI), computed tomography (CT), or ultrasound Comparator(s): No use of imaging Outcome … Intervention(s): Pulsed dye laser treatment Comparator(s): Observation Outcome … , medical therapy using angiotensin-converting enzyme inhibitors (e.g., captopril), observation Outcome

132. Renal-Cancer Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/renal-cancer_research-protocol.pdf
     April 20, 2015 - Detection bias Blinding of outcome assessment Assessments should be made for each main outcome (or … Attrition bias Incomplete outcome data Assessments should be made for each main outcome (or class … 3.3 Was information on intervention status unaffected by knowledge of the outcome or risk of the outcome … measurements within the outcome domain? … (i.e., for each outcome separately).

133. DEcIDE 33: Summary Variables in Observational Resesarch: Propensity Scores and Disease Risk Scores (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/observational-research-scores_research.pdf
     May 01, 2012 - The presence of each of the correlates of outcome confers a different probability of the outcome and … combinations of the variables confer a different probability of the outcome. … In the case of the propensity score, the outcome is treatment choice. … effectiveness outcome. … for a binary outcome with fixed follow-up).

134. Research Protocol: Breast Reconstruction After Mastectomy (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/breast-reconstruction-mastectomy-protocol.pdf
     April 09, 2020 - assessors, and subjective outcome assessors; incomplete outcome data; selective outcome reporting; … assessors, and subjective outcome assessors; incomplete outcome data; selective outcome reporting; … data, selective outcome reporting, and other issues that could be related bias. … Development of a core outcome set for research and audit studies in reconstructive breast surgery. … Developing core outcome sets for clinical trials: issues to consider.

135. Assessing the Risk of Bias in Systematic Reviews of Health Care Interventions (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/ehc-presentation-risk-of-bias.pdf
     December 01, 2017 - allow for different ratings by outcomes • Risk-of-bias ratings for a study may vary according to outcome … to account for outcome specific variations in potential types or extent of bias. … • If presenting a summary, make judgments about overall risk of bias for each included outcome of … Present judgment criteria on individual categories or items, or as a summary for each outcome. … Finally, resolve differences in judgment and record final rating for each outcome. Stage 4.

136. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/inguinal-hernia_research-protocol.pdf
     August 15, 2011 - Outcome data. … Was the outcome measure of interest objective and was it objectively measured? … assessors (#10) (or NR blinded outcome assessors), then it was an objective outcome (#11) o ≤15% … After hernia repair, a key outcome is hernia recurrence, and for this outcome, we define the MCSD as … Thus we propose setting the MCSD at one day for this outcome.

137. Comparative Effectiveness of Surgical Options for Inguinal Hernia | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/inguinal-hernia/research-protocol
     April 11, 2011 - Outcome data. … If NOT blinded outcome assessors (item 10) (or NR blinded outcome assessors), then it was an objective … outcome (item 11) … After hernia repair, a key outcome is hernia recurrence; for this outcome, we define the MCSD as 3 percentage … Thus we propose setting the MCSD at one day for this outcome.

138. Long-Term-Care-Adults Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/long-term-care-adults_executive.pdf
     November 01, 2012 - We aggregated all relevant outcome measures within a particular outcome domain and evaluated strength … Since the outcome domains were assessed as aggregates of relevant outcome measures, the precision score … also reflected how fully the set of outcome measures described the outcome domain. … Summary of key findings and strength of evidence for outcome domains Domain/Outcome Key Findings/Strength … Outcome measures and data collection varied across studies.

139. Slide 1
     effectivehealthcare.ahrq.gov/sites/default/files/study-size-planning-chapter-9.pptx
     January 01, 2013 - DEcIDE Center (Quintiles Outcome, Cambridge, MA) for the Agency for Healthcare Research and Quality … interest for that outcome. … In trials with a continuous outcome, investigators must make assumptions about the standard deviation … of the outcome in each trial arm; when outcome is the necessary occurrence of an event (e.g., death) … Report the primary outcome on which the study size or power estimate is based.

140. The purpose of our tool is to compile a comprehensive list of questions that may be used to evaluate the quality of non-randomized studies of interventions or exposures (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/reliability-testing-grading-evidence_research.pdf
     May 01, 2012 - Summary of RCT risk of bias domain scores, by condition and outcome Condition Outcome Number … Summary of RCT consistency domain scores, by condition and outcome Condition Outcome Number of … Summary of RCT directness domain scores, by condition and outcome Condition Outcome # of Studies … Summary of RCT precision domain scores, by condition and outcome Condition Outcome # of Studies … Strength of evidence grades, by condition and outcome Condition Outcome Individual SOE Grades