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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/pwd-care-interventions-protocol.pdf
February 22, 2019 - Actual outcome measures will be defined by study
authors. … Based on these factors, the overall strength of evidence for each outcome will be
rated as:
• High … To what extent is the primary outcome relevant to
participants? … [5=obviously important; 1=intermediate or
physiologic outcome, requires expert assessment, outcome … Primary
analysis
To what extent are all data included in the analysis of the
primary outcome?
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effectivehealthcare-admin.ahrq.gov/products/dietary-supplements/research-protocol
December 01, 2019 - dietary supplement constituents, quality, and dosage makes it difficult to compare and predict the outcome … In addition to quantitative data for each outcome, definitions, methods used to assess outcomes, and … timing of outcome measurement (such as time from randomization) within each study will be extracted. … e Definition and methods used to assess outcome including timing, and comparability of assessment across … Selective outcome-reporting bias will be evaluated for experimental and cohort studies and incorporated
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effectivehealthcare-admin.ahrq.gov/products/tonsillectomy/research-protocol
March 01, 2020 - Population, intervention, comparator, outcome characteristics*
KQ
Population
Intervention † … "[mh] OR therapy[tiab] OR therapies[tiab] OR therapeutic[tiab] OR therapeutics[tiab] OR outcome[tiab] … Intervention-outcome pairs will be given an overall evidence grade based on the ratings for the individual … We will record strength of evidence assessments in tables, summarizing results for each outcome. … When no studies are available for an outcome or comparison of interest, we will grade the evidence as
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effectivehealthcare-admin.ahrq.gov/products/care-interventions-pwd/protocol
August 01, 2020 - Actual outcome measures will be defined by study authors. … Based on these factors, the overall strength of evidence for each outcome will be rated as:
High: … Common Outcome Measures
Test Name
Domain
Data Source
Reference
BEHAVE-AD …
To what extent is the primary outcome relevant to participants? … [5=obviously important; 1=intermediate or physiologic outcome, requires expert assessment, outcome timing
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/TND-0587-131115.pdf
March 06, 2013 - and management of NMIBC
Comparator(s): Various new and existing therapies and diagnostic approaches
Outcome … characteristics (stage, grade, multiplicity, size, molecular and genetic
alterations) predict oncologic outcome
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/TND_0129_07-13-2009.pdf
January 01, 2009 - status;
geographic region
Comparator(s): non-use of interventions listed above, “standard” care
Outcome … various factors,
interventions, and practices that include cesarean rate as a primary or secondary outcome
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/asthma-provider-adherence_disposition-comments.pdf
May 19, 2013 - Outcome measurements are appropriate. … -The outcome measures are appropriate and clearly defined. … -The criteria for demonstrating a relationship between process outcome
and clinical outcome is not well … and
clinical outcome. … We agree that improved control of asthma
symptoms is an important outcome.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/asthma-provider-adherence_executive.pdf
May 01, 2013 - assessors (detection bias),
incomplete outcome data (attrition bias), selective outcome
reporting … Outcome: Prescription of Controller Medicines
Decision support. … Outcome: Emergency Department Visits/Hospitalizations
Decision support. … Outcome: Missed Days of Work/School
Decision support. … Outcome:
ED Visits/
Hospitalizations
Outcome: Missed
Days of Work/
School
Decision support Benefit
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/inguinal-hernia_disposition-comments.pdf
August 17, 2012 - B is better than A on
outcome X , or A and B yield similar outcome X). … Christine
Chang, AHRQ
Results KQ 2: Outcome: patient satisfaction, page 25: You indicate that
you … The infrequency of the outcome is why the
relative effect sounds larger than an absolute effect. … If the outcome is important but data are
lacking this is important to say. … For the QOL example in KQ1, the outcome was
general quality of life, not a specific aspect of it.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/hypertension-pulmonary-arterial_research-protocol.pdf
January 30, 2013 - One pharmacotherapy versus another pharmacotherapy
Monotherapy versus combination therapy
• Outcome … Patient outcome efficacy:
Intermediate-term outcomes
Hemodynamic parameters such as pulmonary … life (e.g., SF-36, Minnesota Living With Heart Failure
[MLWHF], Cambridge Pulmonary Hypertension Outcome … assessment, incompleteness of outcome data,
selective outcome reporting, and other bias.18 Items are … "[MeSH
Terms] OR outcome[tiab] OR outcomes[tiab] OR "Patient Care Management"[Mesh]
OR treatment[tiab
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effectivehealthcare-admin.ahrq.gov/sites/default/files/product/pdf/postpartum-care-one-year-protocol-amendment.pdf
April 25, 2022 - ● Outcome measurement: For KQ 1a: within 3 months after giving birth. … allocation concealment methodology; blinding of patients, study
personnel/care providers, objective outcome … assessors, and subjective outcome assessors; incomplete
outcome data; selective outcome reporting; … assessors, and
subjective outcome assessors; incomplete outcome data; selective outcome reporting; … characteristics, descriptions of
https://srdrplus.ahrq.gov/
Page 12 of 17
interventions, outcome
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/methods-balancing-harms-benefits_research.pdf
February 01, 2014 - When we weighted stroke as a very important outcome
(weight of 1), MI as an important outcome (weight … of 0.5), and GI bleed as an unimportant
outcome (weight of 0), aspirin was associated with net benefit … (x)
RRx = RR of aspirin for a specific outcome (x)
Nx = Difference in the number of events (N) for … (x), approximates
hazard ratio
Nx = Difference in the number of events (N) for a specific
outcome … Calculating the
number needed to treat for trials where the
outcome is time to an event.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/gastric-cancers-protocol.pdf
January 01, 2024 - data
• Bias in measurement of the outcome
• Bias in selection of the reported result
Each domain … data
• Bias in measurement of the outcome
• Bias in selection of the reported result
Each domain … This rating is made separately for each outcome of each comparison of each KQ. … We will assign a rating of Insufficient when the evidence does not permit a conclusion for the
outcome … Precision is the degree of certainty surrounding an effect estimate with respect
to a given outcome,
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/app-g-surv-report-1-nonopioid-pharmacol-chronic-pain.xlsx
September 20, 2022 - Author, Year Randomization Adequate Allocation Concealment Adequate Patients and Personnel Masked Outcome
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/diverticulitis-research-protocol.pdf
January 01, 2019 - for each
outcome. … The questions will
be assessed for each outcome (e.g., whether each outcome was adjusted for potential … (primarily harms) reporting (for each outcome separately). … Outcome of patients with acute sigmoid diverticulitis:
multivariate analysis of risk factors for free … Diverticulitis in immunosuppressed patients: A
fatal outcome requiring a new approach?
-
effectivehealthcare-admin.ahrq.gov/products/diverticulitis/protocol
October 01, 2019 - for each outcome. … The questions will be assessed for each outcome (e.g., whether each outcome was adjusted for potential … (primarily harms) reporting (for each outcome separately). … Outcome of patients with acute sigmoid diverticulitis: multivariate analysis of risk factors for free … Diverticulitis in immunosuppressed patients: A fatal outcome requiring a new approach?
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/chronic-cough_executive.pdf
March 01, 2014 - We considered meta-analysis for
comparisons where at least three studies reported the
same outcome. … Strength of the Body of Evidence
We rated the strength of evidence for each KQ and
outcome using the … We did not identify any studies evaluating
the comparative therapeutic efficacy or patient outcome … The LCQ and the CQLQ along with its predecessor,
the Adverse Cough Outcome Survey [ACOS]), are
the … Chronic persistent cough in
the adult: the spectrum and frequency of causes and successful
outcome of
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/ptsd-adult-treatment_executive.pdf
April 01, 2013 - Our outcome was the
mean change from baseline to endpoint in CAPS total
score. … Two
reviewers assessed each domain for each key outcome and
resolved differences by consensus. … Below
we summarize the main findings for each KQ by treatment
and outcome, and report the SOE for each … Insufficient
Depression symptoms No included studies reported the outcome Insufficient
Exposure vs. … Another common methodological
limitation was the lack of masking of outcome assessors.
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effectivehealthcare-admin.ahrq.gov/products/abnormal-uterine-bleeding/research-protocol
December 01, 2020 - measure for an outcome listed in the PICOTS
Relevant outcomes must be extractable from data presented … of interest, comparability of cohorts, assessment of outcome, adequate duration of followup, and adequate … Each key outcome on each comparison of interest will be given an overall evidence grade based on the … We will record strength of evidence assessments in tables, summarizing for each outcome.
G. … Clinical outcome of levonorgestrel intra-uterine system in idiopathic menorrhagia.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/evidence-summary-cer-195-uterine-fibroids-final.pdf
December 01, 2017 - Final health outcomes reported in medication studies
Intervention Outcome Category
Studies
Reporting … (s)
Intervention Outcome Category
Studies
Reporting
N
Baseline
Participants
N
Duration of … Levonorgestrel (LNG) IUD improved bleeding (the only
outcome of interest reported); however, the single … Pain improved in up to 84 percent of women in
two studies reporting this outcome. … Treatment satisfaction was high in
seven studies reporting this outcome.