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Showing results for "outcome".

  1. effectivehealthcare-admin.ahrq.gov/products/phenylketonuria/research-protocol
    December 01, 2019 - One comment suggested that "cognitive decline" may not be the most accurate outcome description, so we … changed the phrase to "cognitive impairment," which is a more targeted and measureable outcome. … We will capture all validated outcome measures available within these constructs and report on their … Each key outcome on each comparison of interest will be given an overall evidence grade based on the … We will record strength of evidence assessments in tables, summarizing for each outcome. G.
  2. effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/TND__0250_05-20-2010.pdf
    January 01, 2010 - surgical, ablation) Comparator(s): Different drug and/or device and/or procedure (must have comparator) Outcome … : Different anticoagulant and antiplatelet regimens, LAA occlusive devices (must have comparator) Outcome … and/or statins Comparator(s): Placebo, different ACEIs, ARBs, and/or statins (must have comparator) Outcome
  3. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/care-adults-down-syndrome-protocol-amendment.pdf
    February 05, 2025 - Population, intervention, comparator, outcome, timing, setting (PICOTS) PICOTS KQ1 KQ2 Population Adults … Outcome Benefits: accurate diagnosis, time to diagnosis or intervention/treatment Health and quality … Timing KQ1: There are no restrictions on timing of the intervention, the timing of the outcome or the … Overall risk of bias assessments for each study-outcome will be classified as low, medium, high, or … Based on these factors, the overall strength of evidence for each intervention/comparison/ outcome will
  4. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/bimp-protocol.pdf
    September 27, 2022 - and Quality (AHRQ) is collaborating with the American Headache Society (AHS) and Patient-Centered Outcome … evaluate each to-be-graded outcome reported by each study and assign a risk of bias rating of “high … Although we will assess selective outcome reporting, we will not incorporate it in the overall risk … This rating is made separately for each outcome of each comparison of each KQ. … Precision is the degree of certainty surrounding an effect estimate with respect to a given outcome,
  5. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/structured-handoff-rapid-research.pdf
    January 01, 2025 - Does not measure clinical safety outcome 12. Benjamin MF, Hargrave S, Nether K. … Does not measure clinical safety outcome 32. Fryman C, Hamo C, Raghavan S, et al. … Does not measure clinical safety outcome 33. Hada A, Coyer F. … Does not measure clinical safety outcome 56. Odone A, Bossi E, Scardoni A, et al. … Does not measure clinical safety outcome 67. Sadri A, Dacombe P, Ieong E, et al.
  6. effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/TND_0620_131115.pdf
    March 13, 2013 - and management of MIBC Comparator(s): Various new and existing therapies and diagnostic approaches Outcome … socioeconomic strata) predict oncologic outcome
  7. effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/chronic-cough_research-protocol.pdf
    October 22, 2012 - necessary to begin the process of describing, implementing, and/or developing cough-related health outcome … The grading will be outcome specific such that a given study that analyzes its primary outcome well … but did an incomplete analysis of a secondary outcome would be assigned a different quality grade for … Grading the Evidence for Each Key Question We will grade the strength of evidence for each outcome … Chronic persistent cough in the adult: the spectrum and frequency of causes and successful outcome of
  8. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/kidney-disease-medicine_executive.pdf
    January 01, 2012 - compared with usual protein diets; risk for a composite renal outcome was significantly reduced in … • ACEI significantly reduced risk of composite renal outcome in one of three trials. … • In one trial, ACEI significantly reduced risk of composite renal outcome. … , or composite renal outcome … but not a composite renal outcome
  9. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/renal-artery-stenosis_surveillance.pdf
    June 01, 2012 - CI= 0.069, 1.668, and p=0.183. 13 1 Signal Quality of life: No new evidence was found on this outcome … study was reported to be adequately powered to detect a difference between interventions for this outcome … “In a per-protocol analysis, there Not assessed None 3 experts stated that the result for this outcome … the ASTRAL trial that is included in this report. 7 3 experts stated that the result for this outcome … Clinical and kidney morphologic predictors of outcome for renal artery stenting: data to inform patient
  10. effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/measuring-blood-pressure_research-protocol.pdf
    April 11, 2011 - Quality of life was added as outcome of interest for KQs 1–4 if measured by validated instruments. … o Not just as a device to measure the outcome BP. … of BP control and the health outcomes, in addition to the surrogate outcome cardiac measures. … The grading will be outcome-specific such that a given study that reports its primary outcome well but … did an incomplete analysis of a secondary outcome would be graded of different quality for the two
  11. effectivehealthcare-admin.ahrq.gov/products/maternal-morbidity-mortality/research
    May 01, 2024 - For outcome domains, depression/other mental health outcomes represented a large proportion of the health … related to social and structural determinants of health and at least one health or healthcare-related outcomeOutcome domains included maternal mortality, severe maternal morbidity, hypertensive disorders, gestational
  12. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/app-e-surv-report-2-noninvasive-nonpharma.xlsx
    January 01, 2021 - Allocation Intention to Treat Analysis Baseline Group Similarity Patient Blinded Care Provider Blinded Outcome … Acceptable in All Groups Attrition Reported Attrition Acceptable Attrition B/w Groups Acceptable Timing of Outcome
  13. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/app-e-surv-report-1-noninvasive-nonpharma_0.xlsx
    January 01, 2021 - Allocation Intention to Treat Analysis Baseline Group Similarity Patient Blinded Care Provider Blinded Outcome … Acceptable in All Groups Attrition Reported Attrition Acceptable Attrition B/w Groups Acceptable Timing of Outcome
  14. effectivehealthcare-admin.ahrq.gov/products/cardiac-defibrillators/abstract
    December 01, 2019 - firings will be analyzed by an expert clinical panel to determine if the firing was appropriate and the outcome … The primary outcome will be the time to first appropriate device therapy.
  15. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/dietary-supplements_executive.pdf
    April 01, 2012 - • No relevant outcome was reported in the study or the outcome data were not received from the authors … (Authors were contacted for data clarification and additional outcome data when data were recognized … to have been recorded but not reported in the published study—for example, outcome data without a … of interest (e.g., a surrogate outcome rather than a clinical health outcome), or imprecision in effect … When inconclusive results were associated with a gradable outcome, strength of evidence was deemed
  16. effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/head-neck-cancer-update_research-protocol.pdf
    February 04, 2014 - We will only report outcome data in strata according to prognostic or other patient- related factors … The EPC should specify the comparison and outcome for which the SOE grade applies. … It includes: • Study publication bias (i.e., nonreporting of the full study) • Selective outcome … The overall SOE grade for each outcome will be specifically reported in this table. Table 2. … – Measurements: equal, reliable, and valid (includes masking of outcome assessment).
  17. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/heart-failure-transition-care_executive.pdf
    May 01, 2014 - Two reviewers assessed each domain for each key outcome and determined an overall SOE grade based on … of interest); or (3) no included trials that reported an outcome (NR). … Summary of key findings and strength of evidence, by outcome and intervention category Intervention … at this timepoint). 10 Intervention Category Outcome Outcome Timing N Trials; N Subjects … Limitations also included inadequate sample size and heterogeneity of outcome measures across trials
  18. effectivehealthcare-admin.ahrq.gov/products/schizophrenia-adult/research-protocol
    September 01, 2019 - nonpharmacological treatments for schizophrenia can result in meaningful improvements in a variety of outcome … Ideally, improvements in symptoms translate to long-term clinically relevant positive changes in other outcome … Neurocognitive testing is an intermediate outcome, rather than a patient-centered health outcome, and … If the body of evidence for each intervention and outcome group based on insufficient quality and or … will be initially assessed by one researcher for each key clinical outcome (see PICOTS) by using the
  19. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/ems-blood-transfusion-protocol.pdf
    September 24, 2024 - Scale, Glasgow Outcome Scale Extended, Modified Rankin Scale, Cerebral Performance Category • Length … • Moderate—Confident that the effect estimate lies close to the true effect for this outcome. … • Low—Limited confidence that the estimate of effect lies close to the true effect for this outcome … We will assign a rating of Insufficient when the evidence does not permit a conclusion for the outcome … Precision is the degree of certainty surrounding an effect estimate concerning a given outcome, based
  20. Layout 1 (pdf file)

    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/antipsychotics-children_executive.pdf
    February 01, 2012 - Studies were required to report at least one outcome of interest including symptom improvement, other … Common weaknesses included lack of independent and blind outcome assessment and failure to adequately … Summary of the strength of evidence for symptoms (Key Question 1) Outcome Comparison (# studies) SOE … Summary of the strength of evidence for symptoms (Key Question 1) (continued) Outcome Comparison (# … Summary of the strength of evidence for other short- and long-term outcomes (Key Question 3) Outcome

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