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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/methods-guidance-observational-studies_methods.pdf
June 01, 2010 - Selective outcome reporting can occur in a number of ways, including selective omission of
outcomes … For
example, high-quality observational studies that focus on outcome measures such as persistency … Bias in meta-analysis
due to outcome variable selection within studies. … Outcome reporting bias in randomized trials
funded by the Canadian Institutes of Health
Research. … Precision The degree of certainty surrounding an effect
estimate for a given outcome.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/uterine-fibroids_research-protocol.pdf
March 01, 2016 - Eligible studies must report one or more patient-centered outcome (e.g.,
symptom improvement, blood … on the study
characteristics, intervention(s), comparator(s), arm details, reported outcomes and
outcome … In particular, we hope to estimate probabilities of an
outcome associated with potential trajectories … We will record
strength of evidence assessments in tables, summarizing results for each outcome. … When
no studies are available for an outcome or comparison of interest, we will grade the
evidence
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/breastfeeding_research-protocol.pdf
January 01, 2020 - or practices and attitudes
toward breastfeeding and
complications of lactation
KQ 2: Any other outcome … In order to maintain a consistent
approach, we will conduct a new SOE for each outcome and not use SOE … As described above, in cases where we identify a recent eligible meta-analysis
for an eligible outcome … Two reviewers will assess each domain for
each key outcome, and differences will be resolved by consensus … This is a relevant outcome of
Eligibility osteoporosis, type 2 interest.
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effectivehealthcare-admin.ahrq.gov/products/stem-cell-children/research-protocol
December 01, 2019 - AND
Did the article report on a relevant outcome of interest? … assessment details
identified primary outcome
secondary outcomes
response criteria
use of … measurement instruments are used or not applied at all equally among groups (including not masking outcome … Were outcome measures clearly valid, reliable and equally applied to treatment groups? … Were outcome assessors blind?
Was the length of follow-up adequate?
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effectivehealthcare-admin.ahrq.gov/products/colorectal-surgery-preparation/research-protocol
December 01, 2019 - When possible, outcome data (for beneficial and adverse events) will be evaluated separately for the … Even if the outcome rate is 10 percent (i.e., quite high), the sample size needs to be >400 patients. … The grading will be outcome specific, such that a given study that reports its primary outcome well but … Furthermore, we expect that the completeness of outcome definitions may be suboptimal. … each outcome of interest across studies.
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effectivehealthcare-admin.ahrq.gov/products/breastfeeding/research-protocol
October 01, 2019 - When recent, relevant existing systematic reviews are identified for a particular outcome, we will assess … In order to maintain a consistent approach, we will conduct a new SOE for each outcome and not use SOE … As described above, in cases where we identify a recent eligible meta-analysis for an eligible outcome … Two reviewers will assess each domain for each key outcome, and differences will be resolved by consensus … This is a relevant outcome of interest.
Table 2.
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effectivehealthcare-admin.ahrq.gov/products/weight-gain-prevention/research
December 01, 2019 - interventions and observational studies of approaches with at least 1 year of followup with a weight outcome … We qualitatively synthesized the studies by population, intervention, and outcome. … This lack of blinding of the outcome assessor along with inclusion of studies that were not designed
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effectivehealthcare-admin.ahrq.gov/products/retention-strategies-opioid-use-disorder/rapid-research
December 01, 2020 - Our primary outcome was retention, defined as continued medication engagement for at least 3 months after … 39 primary studies include:
Most studies of MAT for OUD do not focus on retention as the primary outcome … improved outcomes, fewer than half of the identified studies measured treatment retention as a primary outcome
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effectivehealthcare-admin.ahrq.gov/products/antibiotics-respiratory-infection/research
December 01, 2019 - antibiotic resistance is a major goal of these interventions, there were too few studies to assess this outcome … that attempted to assess appropriate prescribing had important limitations and lack of consistency in outcome … No intervention had high-strength evidence for any outcome.
-
effectivehealthcare-admin.ahrq.gov/products/arthritis-knee-physical-therapy/research
December 01, 2019 - osteoarthritis and to examine validity and minimum clinically important differences of the tools for outcome … tests and patient-centered outcomes and minimum clinically important differences in validated tools for outcome … Evidence on longer-term physical therapy effects was available for seven intervention-outcome pairs.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/prostate-cancer-therapies-update_executive.pdf
December 01, 2014 - Outcomes: The primary outcome is overall mortality
or survival. … Timing: Duration of followup was appropriate for the
outcome under consideration. … that was objective
if outcome assessors were not blinded or blinding of
outcome assessors was not … assessors received a lower rating for this
outcome. … Summary of the main findings from randomized controlled trials for Key Question 2
Comparison Outcome
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/autism_executive.pdf
April 01, 2011 - Investigators also failed to report the
outcome that was the primary outcome of a priori
interest and … Cognitive, behavior
and intervention outcome in young children with autism. … Long-term outcome of social skills
intervention based on interactive LEGO© Play. … Do parental
attributions affect treatment outcome in a parenting program? … Treatment outcome
and outcome associations in children with pervasive
developmental disorders treated
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/ptsd-5-final-report-update-2024_0.pdf
January 01, 2024 - • Studies reporting only individual symptoms
or symptom clusters without overall PTSD
outcome
• … , we instead assessed RoB for the PTSD dichotomous outcome in
these three studies. … Post Traumatic Stress Disorder Scale; Y = Yes,
outcome was reported for the study. … Ratings for
additional outcome measures are available in the evidence table. … data or measurement of the outcome (Table 8).
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/ocr-protocol-final_1.pdf
December 18, 2019 - Based
on this prioritized list, the strength of evidence for comparison-outcome pairs within each Key … Question will be initially assessed by one researcher for each clinical outcome (see PICOTS) by
using … or imprecise)
o Degree of certainty surrounding an effect estimate as it relates to a specific
outcome … • High—we are very confident that the estimate of effect lies close to the true effect for this
outcome … In cases where both RCTs and observational studies are included for a
given intervention-outcome pair
-
effectivehealthcare-admin.ahrq.gov/products/cervical-ripening/protocol
May 01, 2020 - Based on this prioritized list, the strength of evidence for comparison-outcome pairs within each Key … Question will be initially assessed by one researcher for each clinical outcome (see PICOTS) by using … :
High—we are very confident that the estimate of effect lies close to the true effect for this outcome … Low—we have limited confidence that the estimate of effect lies close to the true effect for this outcome … In cases where both RCTs and observational studies are included for a given intervention-outcome pair
-
effectivehealthcare-admin.ahrq.gov/products/interventional-treatments-pain/protocol
February 01, 2021 - The strength of evidence for comparison-outcome pairs within each KQ will be initially assessed by one … researcher for each clinical outcome (see PICOTS) by using the approach described in the Methods Guide … The aggregate risk of bias across individual studies reporting an outcome is considered. … Reporting bias (suspected or undetected)
Publication bias, selective outcome reporting, and selective … High: We are very confident that the estimate of effect lies close to the true effect for this outcome
-
effectivehealthcare-admin.ahrq.gov/products/transitions-care-pediatric-adult/protocol
February 01, 2022 - and telehealth) Abbreviations: ER=Emergency room visit; PICOT=population, intervention, comparator, outcome … Actual outcome measures will be defined by authors of published studies. … Additional core outcome sets identified can be seen in Appendix C , which is subject to change according … Based on these factors, the overall strength of evidence or CERQual confidence for each outcome will … Identified Core Outcome Sets. Additional.
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effectivehealthcare-admin.ahrq.gov/products/postpartum-care-one-year/protocol
December 01, 2022 - service is delivered antenatally, the strategy must be aimed at postpartum health (not just that the outcome … Outcome measurement : For KQ 1a: within 3 months after giving birth. … allocation concealment methodology; blinding of patients, study personnel/care providers, objective outcome … assessors, and subjective outcome assessors; incomplete outcome data; selective outcome reporting; and … assessors, and subjective outcome assessors; incomplete outcome data; selective outcome reporting; and
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/bipolar-disorder-treatment_research-protocol.pdf
June 23, 2014 - assessment,
incomplete outcome data (i.e., was incomplete outcome data adequately addressed),
selective … When standard
MIDs for a particular outcome is not available, we will use a statistical difference to … over time to assess
relationships with the outcome. … Who were outcome assessors?
9. … Are reports of the
study free of suggestion
of selective outcome
reporting?
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/fibromyalgia_research-protocol.pdf
April 03, 2014 - Outcomes
Final health outcomes: KQ 1 and some potential measures of each outcome:
§ Overall pain … assessment, incomplete
outcome data, selective reporting, and other sources of bias (i.e., problems … Standardized mean
differences will be calculated for different measures of the same outcome. … Were important
variables known to
impact the
outcome(s)
assessed at
baseline? … Is there
suggestion of
selective outcome
reporting?