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effectivehealthcare-admin.ahrq.gov/products/malnutrition-hospitalized-adults/protocol
December 01, 2020 - PICOTS (Population, Intervention, Comparator, Outcome, Timing, Setting)
Category
Definition … was not provided by the largest report or reports longer followup data for an outcome. … A rating of insufficient will be given when the evidence does not permit a conclusion for the outcome … Precision is the degree of certainty surrounding an effect estimate with respect to a given outcome, … A refined method for the meta-analysis of controlled clinical trials with binary outcome.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-216-telehealth-evidence-summary.pdf
April 01, 2019 - Strength of evidence was assessed for each outcome
and Key Question as described in the Methods
Guide … Inpatient telehealth consultations: strength of evidence
Topic Outcome (KQ)
Number of
Studies (N) … Emergency care telehealth consultations: strength of evidence
Topic Outcome (KQ)
Number
of Studies … All
of these studies addressed at least one intermediate
outcome, and we organized these into three … For 10 topics there were improvements in at
least one intermediate outcome.
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effectivehealthcare-admin.ahrq.gov/products/gestational-diabetes-screening-diagnosis/research-protocol
December 01, 2019 - We will extract data from the primary publication first and then any additional outcome data reported … For each outcome, we will assess four major domains: risk of bias (rated as low, moderate, or high), … When no studies are available for an outcome or the evidence does not permit estimation of an effect, … Hyperglycemia and adverse pregnancy outcome (HAPO) study Cooperative Research Group. … esarean.tw.
75. exp Pregnancy Outcome/
76. pregnanc$ outcome?.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/opioid-treatments-chronic-pain-protocol.pdf
December 19, 2018 - PICOTS
Key
Question
Population Intervention Comparator Outcome
1a, b Adults (age ≥18
years) with … life, doses of
opioids used
8
Key
Question
Population Intervention Comparator Outcome … life; doses of
opioids used
9
Key
Question
Population Intervention Comparator Outcome … Treatment Outcome/
34. … (treatment and (outcome or strateg$ or plan$)).ti,ab,kf.
35. 32 and (33 or 34)
36. limit 35 to yr
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effectivehealthcare-admin.ahrq.gov/products/hypertension-pulmonary-arterial/research-protocol
December 01, 2019 - therapeutic efficacy (clinician judgment about diagnosis/prognosis, choice of treatment)
Patient outcome … of life (e.g., SF-36, Minnesota Living With Heart Failure [MLWHF], Cambridge Pulmonary Hypertension Outcome … assessment, incompleteness of outcome data, selective outcome reporting, and other biases.18 Items are … Grading the Evidence for Each Key Question
We will grade the strength of evidence for each outcome … "[MeSH Terms] OR outcome[tiab] OR outcomes[tiab] OR "Patient Care Management"[Mesh] OR treatment[tiab
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effectivehealthcare-admin.ahrq.gov/products/diabetes-update-2015/research-protocol
December 01, 2019 - ^ We will not evaluate this outcome for metformin vs. sulfonylurea comparisons as the evidence was … § We will evaluate this outcome only for comparisons that include a SGLT-2 inhibitor. … Heterogeneity among the trials for each outcome we consider appropriate for quantitative pooling will … For the outcome of hypoglycemia, we will conduct separate analyses for: (a) severe hypoglycemia and ( … , long-term outcome, and for hypoglycemia.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/grading.ppt
January 01, 2013 - Four Required Domains: Precision Scores
Are rated separately for each important outcome or comparison … Assess separately:
Each required domain (or each optional domain, as relevant)
Each major outcome, … EPC reviewers are not expected to grade every possible comparison for every outcome. … Second, a grade of insufficient is also appropriate when evidence on the outcome is too weak, sparse, … For each outcome of interest, the tables give the numbers of studies and subjects (left column), the
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effectivehealthcare-admin.ahrq.gov/products/breastfeeding-health-outcomes/research
March 01, 2025 - We synthesized the evidence by outcome, summarizing the results of ESRs alongside those of newer primary … The cumulative number of studies included for each outcome varied from only 4 studies examining the relationship … There was no clear “threshold” of breastfeeding that appeared to be most beneficial for any outcome.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/renal-artery-stenosis_appendixes.pdf
April 01, 2005 - Empirical reconstruction of the renal artery:
long-term outcome. … Percutaneous revascularization of the renal
arteries: predictors of outcome. … Predicting the outcome of invasive treatment
of renal artery disease. … Short-
term and long-term outcome following
renovascular reconstruction. … Factors affecting outcome after
percutaneous renal artery stent insertion.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/glaucoma-treatment_research-protocol.pdf
November 16, 2010 - Including treatment convenience as a patient-reported outcome. … Secondary outcome: We will also compare visual acuity outcomes (as measured by the Early
Treatment … Primary outcome:
(1). … assessors (detection bias), incomplete outcome data (attrition bias), selective outcome reporting … If an outcome is evaluated by at least one randomized controlled trial and by observational
studies
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/heart-failure-transition-care_disposition-comments.pdf
May 27, 2014 - (Cochrane review excluded
outcome timings before 6 months). … Thank you, we have collapsed the 3 and 6-
month outcome timings. … As above, we have combined the 3
and 6-month outcome timings. … We only had data for the composite
outcome in a HR. … We have combined the 3 and 6 month outcome
timings but are keeping the 30-day outcome
separate.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/care-adults-down-syndrome-protocol.pdf
July 09, 2024 - Population, intervention, comparator, outcome, timing, setting (PICOTS)
PICOTS KQ1 KQ2
Population Adults … Outcome Benefits: accurate diagnosis, time to
diagnosis or intervention/treatment
Health and quality … Timing KQ1: There are no restrictions on timing of the intervention,
the timing of the outcome or the … Overall risk of bias assessments for each
study-outcome will be classified as low, medium, high, or … Based on these factors, the overall strength of evidence for each intervention/comparison/
outcome will
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/obesity-research-methods_research-protocol.pdf
February 08, 2017 - Most reported the behavioral outcome of
change in caloric intake during a single meal, which was the … outcome used in the meta-
analysis.17
As demonstrated in the review,16 few studies included BMI or … weight as a primary outcome. … Outcome(s) Include:
Outcomes of interest (need one or more of these: See Appendix B, list of outcome … We will describe the effect of the policy/program on each outcome as positive,
neutral, or negative.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/mental-health-children_research-protocol.pdf
December 11, 2015 - We will consider the risk of bias for each relevant outcome of a study. … Necessary conditions (and combinations of
conditions) are antecedent to the outcome: the outcome cannot … Sufficient conditions (and combinations of condition) guarantee the
outcome. … Specify and calibrate outcome set. … We intend to assess “having evidence of
improvement” as our outcome set.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/meditation_research-protocol.pdf
October 17, 2012 - We have refined KQ2 to evaluate the effects on attention as this is a key outcome for understanding … Standardized mean difference (SMD) will be used when the same outcome ( such
as anxiety or depression … We will combine stress and
distress into a single outcome, and also combine
well-being and positive … mood into a single outcome
of positive affect. … study
This valuation is for the group of studies
within an outcome, not an individual study
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/TND-0653-131114.pdf
June 14, 2013 - frenectomy, or frenulotomy
Comparator(s): Breastfeeding management without surgical intervention
Outcome … procedure (pediatricians, dentists,
oral surgeons, or otolaryngologists), are there variations in outcome
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/rotator-cuff-tear_executive.pdf
July 01, 2010 - In addition, studies were
required to report on at least one outcome of interest
(quality of life, function … data, and
standardized/independent approach to outcome
assessment. … Common weaknesses in
the design of the studies included lack of independent
blind outcome assessment … The degree of improvement in functional
outcome scores varied considerably across the
uncontrolled studies … outcome assessment instruments, and
ensuring adequate allocation concealment (where
applicable) and
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effectivehealthcare-admin.ahrq.gov/sites/default/files/presentation.ppt
August 01, 2009 - Example:
Presentation of Data by Outcome and Age
Chung M, et al. … Example: Presentation of Data by Outcome and Age
This is another way to present the available evidence … per outcome and life stage. … Shaded areas mean that the specific outcome/life stage combination was not reviewed because it was not … Outcome super columns (defined by thicker vertical lines labeled “INR<2,” “INR>3” and so on) represent
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/carbohydrate-intake-draft-report.pdf
January 31, 2025 - question
is focused on a distal clinical health outcome (diagnosis of a disease or
condition). … Low Limited confidence that the estimate of effect lies close to the true effect for this
outcome. … ascertainment (e.g.,
use of unvalidated or nonstandardized outcome measures or tests), and settings … Strength of evidence for Key Question 3 (infant intake, infant outcomes)
Outcome Measures Studies (n … This was rated a high risk of bias RCT relative to our question and outcome.
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effectivehealthcare-admin.ahrq.gov/products/care-adults-down-syndrome/protocol
February 01, 2025 - Population, intervention, comparator, outcome, timing, setting (PICOTS) PICOTS KQ1 KQ2 Population Adults … Outcome Benefits: accurate diagnosis, time to diagnosis or intervention/treatment Health and quality … Timing KQ1: There are no restrictions on timing of the intervention, the timing of the outcome or the … KQ2: There are no restrictions on timing of the intervention, timing of the outcome or duration of follow … Based on these factors, the overall strength of evidence for each intervention/comparison/ outcome will