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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/nonpharm-treatment-chronic-pain-protocol.pdf
December 11, 2018 - Short-Form 36 (SF-36) and
EuroQoL-5 Dimensions (EQ-5D) are two such outcome measures and they were … In determining the strength of a body of evidence for each prioritized primary or
safety outcome, the … The aggregate risk of bias
across individual studies reporting an outcome is considered; graded as … • Precision: describes the level of certainty of the estimate of effect for a
particular outcome … Publication bias, selective
outcome reporting, and selective analysis reporting are types of reporting
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effectivehealthcare-admin.ahrq.gov/products/bipolar-disorder-treatment/research-protocol
December 01, 2019 - assessment, incomplete outcome data (i.e., was incomplete outcome data adequately addressed), selective … When standard MIDs for a particular outcome is not available, we will use a statistical difference to … over time to assess relationships with the outcome.
… Who were outcome assessors?
9. … Are reports of the study free of suggestion of selective outcome reporting?
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effectivehealthcare-admin.ahrq.gov/products/cervical-degenerative-disease/protocol
July 01, 2022 - For analysis of continuous measures across the same outcome measures (e.g., VAS for pain) we will report … Based on this prioritized list, the strength of evidence for comparison-outcome pairs within each KQ … The aggregate risk of bias across individual studies reporting an outcome is considered. … Clinical and radiological correlates of severity and surgery-related outcome in cervical spondylosis. … Cervical spondylotic myelopathy: functional and radiographic long-term outcome after laminectomy and
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effectivehealthcare-admin.ahrq.gov/products/noninvasive-nonpharm-pain-update/protocol
May 01, 2020 - Based on input from stakeholders, improvement in function was prioritized as the most important outcome … In determining the strength of a body of evidence for each prioritized primary or safety outcome, the … The aggregate risk of bias across individual studies reporting an outcome is considered; graded as low … Precision: describes the level of certainty of the estimate of effect for a particular outcome with … Publication bias, selective outcome reporting, and selective analysis reporting are types of reporting
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effectivehealthcare-admin.ahrq.gov/products/chronic-cough/research-protocol
December 01, 2020 - necessary to begin the process of describing, implementing, and/or developing cough-related health outcome … The grading will be outcome–specific, such that a given study that analyzes its primary outcome well … but did an incomplete analysis of a secondary outcome would be assigned a different quality grade for … Grading the Evidence for Each Key Question
We will grade the strength of evidence for each outcome … Chronic persistent cough in the adult: the spectrum and frequency of causes and successful outcome of
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effectivehealthcare-admin.ahrq.gov/products/fibromyalgia/research-protocol
December 01, 2019 - We added sleep quality as a final health outcome. … Standardized mean differences will be calculated for different measures of the same outcome. … Were important variables known to impact the outcome(s) assessed at baseline? … Are statistical methods used to assess the primary outcome appropriate to the data? … Is there suggestion of selective outcome reporting?
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effectivehealthcare-admin.ahrq.gov/sites/default/files/product/pdf/methods-guide-inclusion-nonrandomized-studies.pdf
September 01, 2022 - previous
exposure
(intervention)
and the
outcome. … is not in the causal pathway between the treatment and the outcome
(i.e., is not a mediator).48 For … on the intervention status are collected when the outcome or the risk of the
outcome is known, differential … Depending
on knowledge or expectations of the outcome, participants or study personnel may overstate … and not as effects of
the intervention on the outcome.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/wysiwyg/pdf/methods-guide-inclusion-nonrandomized-studies.pdf
September 01, 2022 - previous
exposure
(intervention)
and the
outcome. … is not in the causal pathway between the treatment and the outcome
(i.e., is not a mediator).48 For … on the intervention status are collected when the outcome or the risk of the
outcome is known, differential … Depending
on knowledge or expectations of the outcome, participants or study personnel may overstate … and not as effects of
the intervention on the outcome.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/effect-protein-intake-protocol-amendment.pdf
November 29, 2023 - Inclusion and Exclusion criteria by Population, Intervention, Comparator,
Outcome, Timing, Setting/Study … data; 4) Bias in
measurement of the outcome; 5) Bias in selection of reported result. … For RCTs, the
overall risk of bias assessments for each study outcome will be classified as low risk … controlled trials and observational
studies, the overall risk of bias assessments for each study outcome … The results will be organized by life
stage, intervention, and then by targeted outcome.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/dyspnea-protocol-amended.pdf
May 19, 2020 - Ideally, the outcome of breathlessness for intervention studies should be a comprehensive
assessment … Outcomes All studies must evaluate an outcome
of interest as defined by KQ1-4*
• We will exclude … for Conducting Comparative Effectiveness Reviews.13
Following this standard approach, for each key outcome … When the body of evidence for a key outcome includes both RCTs and other
intervention studies with … May
19th,
2020
Outcome Complementary
and alternative
medicine
interventions
Integrative
medicine
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effectivehealthcare-admin.ahrq.gov/products/measuring-blood-pressure/research-protocol
March 01, 2020 - Quality of life was added as outcome of interest for KQs 1–4 if measured by validated instruments. … Not just as a device to measure the outcome BP. … Analytic Framework
* Key Question 4 relates to the link between the specific intermediate outcome … of BP control and the health outcomes, in addition to the surrogate outcome cardiac measures. … The grading will be outcome-specific such that a given study that reports its primary outcome well but
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effectivehealthcare-admin.ahrq.gov/sites/default/files/ijzerman_ahrq-webinar-mcda.pdf
January 01, 2011 - Integration of preferences in quantitative framework
2
I want the best treatment:
Clinical Outcome … to determine
the relative preference for the alternatives:
I want the best treatment:
Clinical Outcome … Response Remission Relaps
patients
experts
effectiveness Quality of life Adverse events
Rank 1 Outcome … measure for psychiatrists
Rank 1 Outcome measure for patients
Danner, Hummel et al.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/omega-3-maternity_executive.pdf
October 01, 2016 - Outcome data
were abstracted by a biostatistician and audited by an
experienced reviewer. … For trials that had groups with the same
intervention but with varying doses, we averaged the
outcome … Outcome measures for
depression were heterogeneous so meta-analysis is not
appropriate. … measures, but they seldom attempted to account for these
changes in outcome measures. … A refined method for the meta-analysis
of controlled clinical trials with binary outcome.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/study-design-classification_research.pdf
December 01, 2010 - and those who do not have the outcome of interest (controls). … (s), and timing of outcome assessments? … (s), and timing of
outcome assessments). … and those who do
not have the outcome of interest (controls). … Outcome Intervention
Were the
groups
defined by
intervention or
outcome?
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/nursing-staff-shortages-rapid-research-appendix-c.xlsx
January 01, 2024 - That is, for each outcome category, the corresponding interventions differed. 1. … Findings Patient Satisfaction Outcome Findings Nursing Staff Outcome Findings Other Relevant Outcomes … Findings Patient Satisfaction Outcome Findings Nursing Staff Outcome Findings Other Relevant Outcomes … Findings Patient Satisfaction Outcome Findings Nursing Staff Outcome Findings Other Relevant Outcomes … Findings Patient Satisfaction Outcome Findings Nursing Staff Outcome Findings Other Relevant Outcomes
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effectivehealthcare-admin.ahrq.gov/products/head-neck-cancer-update/research-protocol
December 01, 2019 - We will only report outcome data in strata according to prognostic or other patient- related factors … The EPC should specify the comparison and outcome for which the SOE grade applies. … Evidence may be indirect in several situations such as:
The outcome being graded is considered … It includes:
Study publication bias (i.e., nonreporting of the full study)
Selective outcome … The overall SOE grade for each outcome will be specifically reported in this table.
Table 2.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/ischemic-stroke-treatment_research-protocol.pdf
February 19, 2010 - The intermediate outcome is
recanalization. … (e.g.,
recanalization, mortality, mRS, or outcome score including NIHSS, Barthel Index or GOS) or … , ≥3=poor outcome), NIHSS score [including a
NIHSS decrease ≥ 4 points deemed significant by the FDA … For prospective and retrospective studies enrolling
consecutive patients, we will assess if outcome … Food and Drug Administration
GOS Glascow Outcome Scale
IA Intraarterial
ICH Intracerebral
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/transparency-tympanostomy_research-protocol.pdf
September 02, 2016 - Background
Information biases, including publication bias, time-lag bias, selective outcome reporting … At the level of
the evidence-base, and for each pertinent exposure-outcome relationship, we will assess … For outcome
instantiations that are reported in both, we will record whether the quantitative results … Outcome reporting in industry-sponsored
trials of gabapentin for off-label use. … Outcome reporting bias in randomized
trials funded by the Canadian Institutes of Health Research.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/patient-generated-health-data-protocol-chronic-conditions.pdf
March 17, 2020 - interventions, such as cost per QALY, were included if effectiveness was
measured using a health outcome … compared across various interventions and are not
standardized relative to a consumer or societal outcome … If the results for another outcome have inconsistency in direction of effect and/or
study authors could … not reach a conclusion, the findings will be coded as “unclear” for
that outcome. … or an
outcome that defines a
clinical condition of interest.
-
effectivehealthcare-admin.ahrq.gov/products/glaucoma-treatment/research-protocol
December 01, 2019 - (Key Question 2)
Including treatment convenience as a patient-reported outcome. … Outcomes
Outcomes for Key Question 1:
Primary outcome: The proportion of participants with moderate … assessors (detection bias), incomplete outcome data (attrition bias), selective outcome reporting (reporting … If an outcome is evaluated by at least one randomized controlled trial and by observational studies, … If an outcome is evaluated by one or no randomized controlled trials, our evidence grade will be based