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effectivehealthcare-admin.ahrq.gov/sites/default/files/s158.pdf
October 01, 2007 - Availability of information on disease outcome will affect
choice of analytic strategies. … Using an external validation study
without data on disease outcome to adjust for unmeasured confound- … PSC uses validation data without information on
disease outcome under a strong assumption. … †Internal validation studies contain information on disease outcome of interest by design. … Using the outcome for
imputation of missing predictor values was preferred.
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effectivehealthcare-admin.ahrq.gov/products/indirect-comparisons/research-2013
November 01, 2017 - Evidence Reports
A Bayesian Missing Data Framework for Multiple Continuous Outcome … SHARE:
A Bayesian Missing Data Framework for Multiple Continuous Outcome … Methods
After a review of existing hierarchical Bayesian methods for MTCs with a single continuous outcome … Research Report:
A Bayesian Missing Data Framework for Multiple Continuous Outcome
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effectivehealthcare-admin.ahrq.gov/sites/default/files/cer-238-cervical-ripening-evidence-summary.pdf
March 01, 2021 - If a prespecified, primary outcome is not listed in a table below that
• Low-strength evidence suggested … The highest strength of evidence found for any outcome was low
strength. … Primary birth outcome: cesarean delivery
Key
Question Intervention Findingsa Studies Incidence
Relative … Primary fetal harms outcomes
Key
Question Intervention Outcome Findingsa Studies Incidence
Relative … There was variation in outcome definition and reporting
across the studies, with many reporting outcomes
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effectivehealthcare-admin.ahrq.gov/products/medical-tests-proposals/research
December 01, 1969 - Yet “the ultimate value of the diagnostic test is that difference in health outcome resulting from the … test: In what ways, to what extent, with what frequency, in which patients is health outcome improved … Evaluations in terms of patient outcome can be found in all of the retrieved models except the one by … Most proposals are built on the chain of steps linking tests and outcome, and they can be traced back … In general, their object of study is clinician behavior, not patient outcome.
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effectivehealthcare-admin.ahrq.gov/products/fecal-incontinence/research-protocol
December 01, 2019 - assessment, incomplete outcome data, selective outcome reporting, and other sources of bias (i.e., problems … Outcome measures for fecal incontinence: anorectal structure and function. … Were important variables known to impact the outcome(s) assessed at baseline? … Are statistical methods used to assess the primary outcome appropriate to the data? … Is there suggestion of selective outcome reporting?
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/TND-0520-131115.pdf
November 15, 2013 - myocardial perfusion
imaging, and echocardiography)
Comparator(s): Another NIT or coronary angiography
Outcome … comparative diagnostic accuracy, diagnostic thinking, and therapeutic and
from Nominator: patient outcome … focus on NITs to diagnose symptomatic patients
with suspected CAD and solely on the test accuracy outcome … in the asymptomatic populations, and looked at outcomes other than test
performance (e.g., clinical outcome
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/instrumental-variable-methods_research.pdf
April 01, 2010 - between the actual
treatment taken by the patient and the outcome will be confounded. … Assumption 3 states that the
instrument should affect the outcome only via treatment. … Preference must only affect the outcome
through its influence on the treatment under study. … could affect the outcome were different over the weekend. … Below, let outcome be the outcome, exp be the exposure, iv be the instrument, age be a
continuous age
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/saturated-fat-replacement-protocol.pdf
January 01, 2024 - Study eligibility criteria based on Population, Intervention, Comparator, Outcome (PICO),
and other … In all instances, if a study meets eligibility criteria for any outcome, we will extract all outcomes … even though the study might
not have met study size criteria for that specific outcome. … assessor blinding are
all unclear (with the recognition that the participant may be the outcome assessor … Grading the Strength of Evidence for Each Outcome
Following AHRQ Methods guidance,14 the review team
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/polyunsaturated-fatty-protocol.pdf
January 01, 2024 - Study eligibility criteria based on Population, Intervention, Comparator, Outcome (PICO),
and other … In all instances, if a study meets eligibility criteria for any outcome, we will extract all outcomes … even though the study might
not have met study size criteria for that specific outcome. … assessor blinding are
all unclear (with the recognition that the participant may be the outcome assessor … Grading the Strength of Evidence for Each Outcome
Following AHRQ Methods guidance,11 the review team
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effectivehealthcare-admin.ahrq.gov/products/glaucoma-screening/research-protocol
December 01, 2019 - Patient satisfaction ( Secondary outcome ). … Outcome for Key Question 6:
The proportion of participants experiencing the following adverse events … assessors (detection bias), incomplete outcome data (attrition bias), selective outcome reporting (reporting … If an outcome is evaluated by at least one randomized controlled trial and by observational studies, … If an outcome is evaluated by one or no randomized controlled trials, our evidence grade will be based
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/cesarean-birth-2010_research-protocol.pdf
January 01, 2010 - in two and as a
secondary outcome in four others. … Additional nonrandomized controlled trials
that had cesarean rate as a primary or secondary outcome … Abbreviations: PICOTS = population, intervention, comparator, outcome, timing, and setting. … of
interest, comparability of cohorts, assessment of outcome, adequate duration of followup, and … We will record strength of
evidence assessments in tables, summarizing for each outcome.
G.
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effectivehealthcare-admin.ahrq.gov/products/autism-medical-update/research-protocol
January 01, 2019 - Outcomes
We will address the following broad outcome categories. … We will assess the risk of bias based upon the study-defined primary outcome(s). … No confidence in the estimate of effect for this outcome. … Young Adult Outcome of Autism Spectrum Disorders. … Adult outcome for children with autism. J Child Psychol Psychiatry 2004 Feb;45(2):212-29.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/assessing-the-risk-of-bias_draft-report.pdf
June 02, 2011 - Blinding of outcome
assessors, especially with
subjective outcome
assessments, bias in
inferential … reporting for another outcome. … Alternatively, with no evidence of selective outcome reporting for an individual outcome, EPCs
may … still judge that selective outcome reporting exists for the body of evidence for that outcome
alone … of the outcome data in studies reporting that outcome.
9
This overall risk-of-bias is
dictated by
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/pharma-nonpharma-ptsd-2022-update-app-g2-3.xlsx
January 01, 2022 - Outcome Data (Cochrane) or Attrition Bias (AHRQ); Attrition Bias Due to Missing Outcome Data (Cochrane … Measurement Risk of Bias in Measurement of the Outcome (Cochrane) or Detection Bias (AHRQ); Outcome … Risk of Bias in Measurement of the Outcome (Cochrane) or Detection Bias (AHRQ); Outcome Measurement … Risk of Bias in Measurement of the Outcome (Cochrane) or Detection Bias (AHRQ); Outcome Measurement Risk … of Bias in Measurement of the Outcome (Cochrane) or Detection Bias (AHRQ); Outcome Measurement: RoB
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/quantitative-synthesis-expanded-methods_methods.pdf
March 01, 2013 - If a composite
outcome is time-to-event, it takes the value of the time until the first event. … Although the use of a
composite outcome as the primary outcome in a clinical trial can reduce sample … • Interpretation of composite outcome results is fraught. … Criteria for selecting
outcomes for
combining
Outcome
definitions
Specify whether outcome definitions … This should be done
for each outcome considered.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/patient-monitoring-systems-rapid-review.pdf
December 01, 2024 - .
3.2.1.1.4 Hospital Mortality
Both studies examined this outcome. … For the outcome of cardiorespiratory arrest, a score had little impact. … PMID: 29870923. - No outcome of
interest
15. Durden L, Wilford BN. … PMID: 36692798. - No outcome of
interest
53. Petersen JA. … PMID: 31002971. - No outcome of
interest
Pub.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/trauma-informed-care-protocol.pdf
April 19, 2023 - Population, intervention, comparator, outcome, timing, setting (PICOTS)
PICOTS KQ1 KQ2
Population … blinding (performance and detection
bias), completeness of follow-up (attrition bias), analyses and outcome … Overall risk of bias assessments for each
study-outcome will be classified as low, high, or unclear … Based on these factors, the overall strength of evidence for each intervention/comparator/
outcome will … Childhood maltreatment predicts unfavorable course of illness
and treatment outcome in depression: a
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/TND_0715-140408.pdf
April 08, 2014 - Children with infantile hemangiomas
Intervention(s): Early referral
Comparator(s): Delayed referral
Outcome … resonance imaging (MRI),
computed tomography (CT), or ultrasound
Comparator(s): No use of imaging
Outcome … Intervention(s): Pulsed dye laser treatment
Comparator(s): Observation
Outcome … ,
medical therapy using angiotensin-converting enzyme inhibitors
(e.g., captopril), observation
Outcome
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/renal-cancer_research-protocol.pdf
April 20, 2015 - Detection bias
Blinding of outcome assessment
Assessments should be made for
each main outcome (or … Attrition bias
Incomplete outcome data
Assessments should be made for
each main outcome (or class … 3.3 Was information on intervention status unaffected by knowledge of the outcome or risk
of the outcome … measurements within the outcome domain? … (i.e., for each outcome separately).
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/observational-research-scores_research.pdf
May 01, 2012 - The presence of each of the correlates of outcome confers a different
probability of the outcome and … combinations of the variables confer a different probability of the
outcome. … In the case of the propensity score, the
outcome is treatment choice. … effectiveness
outcome. … for a
binary outcome with fixed follow-up).