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301. Continuous Respiratory Monitoring and a “Smart” Infusion System Improve Safety of Patient-Controlled Analgesia in the Postoperative Period (pdf file)
     www.ahrq.gov/sites/default/files/wysiwyg/professionals/quality-patient-safety/patient-safety-resources/resources/advances-in-patient-safety-2/vol4/Advances-Maddox_111.pdf
     June 18, 2008 - Accurate dosing and administration of opioids are critical. … Misprogramming IV infusion pumps can result in serious, potentially life threatening adverse events.20 Opioid … analgesics are associated with a high risk of harm. … Due to the variability of patient response to opioid analgesics, even when correctly programmed, therapeutic … Dangers of postoperative opioids.

302. Psn-Pdf (pdf file)
     psnet.ahrq.gov/node/45959/psn-pdf
     June 29, 2017 - https://psnet.ahrq.gov/issue/impact-opioid-safety-initiative-opioid-related-prescribing-veterans Opioids … intervention reduced two unsafe prescribing practices: high-dose opioid prescriptions and concurrent use of opioids … 2011-2015 https://psnet.ahrq.gov/issue/mandatory-provider-review-and-pain-clinic-laws-reduce-amounts-opioids-prescribed-and-overdose … https://psnet.ahrq.gov/issue/cdc-guideline-prescribing-opioids-chronic-pain-united-states-2016 https

303. Psn-Pdf (pdf file)
     psnet.ahrq.gov/node/45979/psn-pdf
     April 05, 2017 - issue/healthcare-system-wide-implementation-opioid-safety-guideline- recommendations-case-urine-drug Opioids … from 2010 to 2013, the risk of suicide and overdose events among VA patients receiving prescription opioids … opioid-prescribing-after-nonfatal-overdose-and-association-repeated-overdose-cohort-study https://psnet.ahrq.gov/issue/cdc-guideline-prescribing-opioids-chronic-pain-united-states … -2016 https://psnet.ahrq.gov/issue/hospital-prescribing-opioids-medicare-beneficiaries https://psnet.ahrq.gov

304. Psn-Pdf (pdf file)
     psnet.ahrq.gov/node/46820/psn-pdf
     August 20, 2018 - issue/postsurgical-prescriptions-opioid-naive-patients-and-association-overdose- and-misuse Harm from opioids … investigators examined the effect of postoperative opioid prescribing in patients who had never received opioids … As with prior studies, they found increased subsequent misuse of opioids among patients who received … patient-safety-and-opioid-medications https://psnet.ahrq.gov/issue/wide-variation-and-overprescription-opioids-after-elective-surgery

305. Effect of a Veterans Health Administration mandate to case review patients with opioid prescriptions on mortality among patients with opioid use disorder: a secondary analysis of the STORM randomized control trial. | PSNet
     psnet.ahrq.gov/issue/effect-veterans-health-administration-mandate-case-review-patients-opioid-prescriptions
     May 18, 2022 - Patients whose opioids were discontinued after case review showed even higher odds of mortality. … Association of dose tapering with overdose or mental health crisis among patients prescribed long-term opioids … An electronic intervention to improve safety for pain patients co-prescribed chronic opioids … April 7, 2019 Association between concurrent use of prescription opioids and benzodiazepines

306. EHC Protocol: Making Healthcare Safer IV: Opioid Stewardship (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs4-opioid-stewardship-protocol.pdf
     July 01, 2023 - What patient safety measures or indicators have been used to examine the harms associated with opioids … practices that have been used to prevent or mitigate the harms associated with prescribed or ordered opioids … However, opioids also carry well known risks, including for overdose, misuse, and opioid use disorder … The updated CDC Clinical Practice Guideline for Prescribing Opioids for Pain provides guidelines for … CDC Clinical Practice Guideline for Prescribing Opioids for Pain - United States, 2022.

307. Psn-Pdf (pdf file)
     psnet.ahrq.gov/node/47526/psn-pdf
     January 16, 2019 - US national trends in pediatric deaths from prescription and illicit opioids, 1999–2016. … US National Trends in Pediatric Deaths From Prescription and Illicit Opioids, 1999-2016. … https://psnet.ahrq.gov/issue/us-national-trends-pediatric-deaths-prescription-and-illicit-opioids-1999 … https://psnet.ahrq.gov/issue/us-national-trends-pediatric-deaths-prescription-and-illicit-opioids-1999

308. Psn-Pdf (pdf file)
     psnet.ahrq.gov/node/46119/psn-pdf
     August 15, 2018 - Recent studies have shown that opioids are frequently prescribed in situations where there is little … Investigators found that patients with more severe injuries were more likely to be prescribed opioids … , focusing primarily on reducing opioid use for chronic noncancer pain (where there is no evidence opioids … are beneficial) while not denying opioids to those in acute pain from trauma or other reasons.

309. Psn-Pdf (pdf file)
     psnet.ahrq.gov/node/74075/psn-pdf
     November 17, 2021 - cdc-guideline-opioid-prescribing-associated-reduced-dispensing-certain- patients-chronic-pain Misuse of prescription opioids … release of the 2016 guidelines was associated with reductions in the percentage of patients receiving opioids … perspective/opioid-overdose-patient-safety-problem https://psnet.ahrq.gov/issue/cdc-guideline-prescribing-opioids-chronic-pain-united-states

310. Topic-Brief3-Sud (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/topic-brief3-SUD.pdf
     April 01, 2021 - analgesics.30 In patients on higher doses of buprenorphine, continuing the buprenorphine but decreasing … studies40,41 in the review reported that patients taking buprenorphine were effectively treated for pain with opioid … analgesics while continuing buprenorphine … Use and misuse of opioids in chronic pain. … Opioid analgesics play an essential role in treating pain, and pain management in the context of the

311. Topic-Brief3-Sud (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/topic-brief3-SUD.pdf
     April 01, 2021 - analgesics.30 In patients on higher doses of buprenorphine, continuing the buprenorphine but decreasing … studies40,41 in the review reported that patients taking buprenorphine were effectively treated for pain with opioid … analgesics while continuing buprenorphine … Use and misuse of opioids in chronic pain. … Opioid analgesics play an essential role in treating pain, and pain management in the context of the

312. The prescription opioid crisis: role of the anaesthesiologist in reducing opioid use and misuse. | PSNet
     psnet.ahrq.gov/issue/prescription-opioid-crisis-role-anaesthesiologist-reducing-opioid-use-and-misuse
     November 16, 2022 - March 8, 2023 Inappropriate prescribing of opioids for patients undergoing surgery.

313. 2018 National Healthcare Quality and DIsparities Report (pdf file)
     www.ahrq.gov/sites/default/files/wysiwyg/research/findings/nhqrdr/2018qdr-final-es.pdf
     September 01, 2019 - Hospital Stays Involving Opioids Suicide Deaths Trends in Healthy Living Importance of Healthy … Financial Barriers to Medical Care Adolescent Vaccination Emergency Department Visits Involving Opioids … Hospital Inpatient Stays Involving Opioids Disparities by Insurance Status Largest Disparities … Mortality Overdose Deaths Involving Any Opioid Overdose Deaths Involving Natural and Semisynthetic Opioids … and Overdose Deaths Involving Synthetic Opioids Other Than Methadone Maternal Morbidity and Mortality

314. Adverse and Temporary Harm Events in Long-Term-Care Hospitals (LTCH) Designated in Office of Inspector General Report1 as Clearly Preventable or Likely Preventable, by Clinical Category (pdf file)
     pso.ahrq.gov/sites/default/files/wysiwyg/oig-list-long-term-care-hospitals-2019.pdf
     January 01, 2019 - hospital for treatment • Aspiration pneumonitis/pneumonia with inadequate preventive care • Cascade with opioids … pain and anti-anxiety medication (opioid and benzodiazepine [diazepam]) • Mental status changes due to opioid … analgesics (intravenous hydromorphone) • Somnolence due to anti-anxiety medications (lorazepam and clonazepam … frequent falls resulting in back pain • Cascade with oversedation and hypotension while on multiple opioids … alprazolam) medication • Somnolence while on anti-anxiety medication (alprazolam) • Somnolence while on opioids

315. Disposition of Comments: Comparative Effectiveness Review No. 232_Interventions for Breathlessness in Patients With Advanced Cancer (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/cer-232-breathlessness-cancer-comments.pdf
     November 19, 2020 - Some were using opioids for treatment (e.g. … of opioids on dyspnea. … Opioids are similar enough pharmacologically that we have combined the different types of opioids together … “high dose and low dose opioids”. … the use of opioids, and in particular systemic opioids in the relief of dyspnea in cancer patients

316. No shortcuts to safer opioid prescribing. | PSNet
     psnet.ahrq.gov/issue/no-shortcuts-safer-opioid-prescribing
     March 30, 2016 - Related Resources From the Same Author(s) CDC guideline for prescribing opioids … private Insurance, 2017 June 10, 2020 CDC Clinical Practice Guideline for Prescribing Opioids … 1, 2018 Mandatory provider review and pain clinic laws reduce the amounts of opioids … and Quality April 26, 2023 CDC Clinical Practice Guideline for Prescribing Opioids

317. AHRQ Statistical Brief (pdf file)
     meps.ahrq.gov/data_files/publications/st515/stat515.pdf
     September 01, 2018 - AHRQ Statistical Brief STATISTICAL BRIEF #515 September 2018 Any Use and Frequent Use of Opioids among … Introduction Currently in the United States, prescription opioids are commonly used to treat both chronic … Poverty status The likelihood of any use and frequent use of outpatient prescription opioids tended to … Definitions Opioids In this Statistical Brief, we examine outpatient prescription fills of opioids that … These opioids are identified using generic drug names for narcotic analgesics and narcotic analgesic

318. Infographic - Opioid Outpatient Prescriptions Dispensed to Adults, 2017 (pdf file)
     www.ahrq.gov/sites/default/files/wysiwyg/data/infographics/opioids-dispensed.pdf
     June 02, 2025 - Infographic - Opioid Outpatient Prescriptions Dispensed to Adults, 2017

319. AHRQ Statistical Brief (pdf file)
     meps.ahrq.gov/data_files/publications/st516/stat516.pdf
     September 01, 2018 - AHRQ Statistical Brief STATISTICAL BRIEF #516 September 2018 Any Use and Frequent Use of Opioids among … Introduction Currently in the United States, prescription opioids are commonly used to treat both chronic … Definitions Opioids In this Statistical Brief, we examine outpatient prescription fills of opioids that … These opioids are identified using generic drug names for narcotic analgesics and narcotic analgesic … We identify slightly more opioids commonly used for pain than one would find in the MEPS public use

320. Cer-250-Cannabis-2024-Surv-Rep-Update-Table-E5 (xls file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-2024-surv-rep-update-table-e5.xlsx
     January 01, 2024 - B Between-cohort differences in discontinuation of strong opioid analgesics: 71.6% vs. 33.8%, p<0.001 … analgesics as an add-on treatment Mean (SD) A: 6.2 (2.4) sprays/day (16.74 mg THC/15.5 mg CBD) B: MME … B Mean number of background pain medications use at 6 months: Mild opioid analgesics: 0.02 (SD 0.14) … vs. 0.07 (SD 0.27) Strong opioid analgesics: 0.22 (SD 0.59) vs. 0.21 (SD 0.60) Mean rescue pain medication … use at 6 months: Mild opioid analgesics: 0.00 (SD 0.06) vs. 0.04 (SD 0.20) Strong opioid analgesics: