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21. Opioid Safety | PSNet
    psnet.ahrq.gov/primer/opioid-safety
    September 07, 2019 - Although this class of medications has always been considered high risk, prescribing of opioids increased … For many years, opioids were routinely prescribed for pain of any etiology, despite the fact that opioids … their withdrawal from prescription opioids. … Newer synthetic opioids were introduced to the market in the late 1990s and were aggressively marketed … Studies of the epidemiology of adverse drug events in the early 2000s consistently found that opioids

22. Opioids in Medicare Part D: Concerns About Extreme Use and Questionable Prescribing. | PSNet
    psnet.ahrq.gov/issue/opioids-medicare-part-d-concerns-about-extreme-use-and-questionable-prescribing
    October 29, 2008 - Misuse of prescription opioids represents a serious patient safety issue. … HHS Guide for Clinicians on the Appropriate Dosage Reduction or Discontinuation of Long-Term Opioid … Analgesics. … HHS Guide for Clinicians on the Appropriate Dosage Reduction or Discontinuation of Long-Term Opioid … Analgesics.

23. Quantifying the burden of opioid medication errors in adult oncology and palliative care settings: a systematic review. | PSNet
    psnet.ahrq.gov/issue/quantifying-burden-opioid-medication-errors-adult-oncology-and-palliative-care-settings
    May 22, 2019 - Opioids are commonly used to manage pain in patients with cancer and those near the end of life. … Although opioids offer many therapeutic benefits, they are also a known high-risk medication . … November 25, 2009 Prescription opioid analgesics commonly unused after surgery: a systematic … May 30, 2018 Opioids and Dentistry. … August 23, 2017 Prescription opioid analgesics commonly unused after surgery: a systematic

24. Opioids and falls risk in older adults: a narrative review. | PSNet
    psnet.ahrq.gov/issue/opioids-and-falls-risk-older-adults-narrative-review
    June 22, 2022 - Review Opioids and falls risk in older adults: a narrative review. … Opioids and falls risk in older adults: a narrative review. … This article summarizes the relationship between prescription opioids and risk of falls among older … Opioids and falls risk in older adults: a narrative review.

25. Patient Options for Safe and Effective Disposal of Unused Opioids. | PSNet
    psnet.ahrq.gov/issue/patient-options-safe-and-effective-disposal-unused-opioids
    March 13, 2019 - Book/Report Patient Options for Safe and Effective Disposal of Unused Opioids. … Examining programs to safely collect unused prescription opioids for disposal and patient awareness … that many adults are unaware these programs exist or choose to retain or sell unused prescription opioids … August 15, 2018 Prescription Opioids: Medicare Needs to Expand Oversight Efforts to Reduce … March 30, 2022 Proposed 2022 CDC clinical practice guideline for prescribing opioids.

26. Physician prescribing of opioids to patients at increased risk of overdose from benzodiazepine use in the United States. | PSNet
    psnet.ahrq.gov/issue/physician-prescribing-opioids-patients-increased-risk-overdose-benzodiazepine-use-united
    July 27, 2016 - Study Emerging Classic Physician prescribing of opioids … Physician Prescribing of Opioids to Patients at Increased Risk of Overdose From Benzodiazepine Use in … Patients prescribed opioids and benzodiazepines concurrently may be at increased risk for adverse … Physician Prescribing of Opioids to Patients at Increased Risk of Overdose From Benzodiazepine Use in … April 7, 2021 Assessment of potentially inappropriate prescribing of opioid analgesics

27. A Lot of Pain (Medications) | PSNet
    psnet.ahrq.gov/web-mm/lot-pain-medications
    April 27, 2016 - List key principles in safe prescribing of opioids in the hospital. … using at least two different classes of analgesics.( 6 ) Once a decision has been made to use opioid … analgesics to manage acute post-operative pain, identifying the optimal drug, dose, route, and regimen … When adding additional opioids for acute pain, immediate-release opioids should be used to facilitate … Always combine opioid and non-opioid analgesics to maximize analgesia and reduce opioid requirements.

28. Opioid Overdose as a Patient Safety Problem | PSNet
    psnet.ahrq.gov/perspective/opioid-overdose-patient-safety-problem
    May 01, 2017 - Prescribing fewer opioids is important because there is a direct association between the volume of opioids … Number and age-adjusted rates of drug-poisoning deaths involving opioid analgesics and heroin: United … Cohort study of the impact of high-dose opioid analgesics on overdose mortality. … Opioids have been around for forever. … And 10% of them were using opioids a year later.

29. Spotlight (pdf file)
    psnet.ahrq.gov/sites/default/files/2021-09/spotlight_lost_in_transitions_of_care_09.22.2021_final.pdf
    January 01, 2021 - analgesics daily are often presumed to be opioid tolerant, and therefore at lower risk of overdose … analgesics among patients with acute severe pain due to sickle cell disease or active cancer, it is … Obtain baseline liver function tests. 49 Methadone and Buprenorphine (5) • Conversion from other opioid … analgesics to methadone is variable and not linear (i.e., the higher the total daily dose (TDD) of … Extended-release (ER) and long-acting (LA) opioid analgesics Risk Evaluation and Mitigation Strategy

30. Lost in Transitions of Care: Managing an Opioid-Dependent Patient with Frequent Hospitalizations | PSNet
    psnet.ahrq.gov/web-mm/lost-transitions-care-managing-opioid-dependent-patient-frequent-hospitalizations
    October 27, 2022 - Patients with chronic pain who are taking opioid analgesics daily are often presumed to be opioid tolerant … dose tables, and the lack of evidence supporting use of these tables in converting between different opioid … analgesics among patients with acute severe pain due to sickle cell disease or active cancer, it is … analgesics to methadone is variable and not linear. … Extended-release (ER) and long-acting (LA) opioid analgesics Risk Evaluation and Mitigation Strategy

31. How to maximize patient safety when prescribing opioids. | PSNet
    psnet.ahrq.gov/issue/how-maximize-patient-safety-when-prescribing-opioids
    May 03, 2006 - Review How to maximize patient safety when prescribing opioids. … How to Maximize Patient Safety When Prescribing Opioids. … How to Maximize Patient Safety When Prescribing Opioids. … October 5, 2022 Opioids and falls risk in older adults: a narrative review. … May 16, 2018 Opioids and Dentistry.

32. Reducing Adverse Drug Events Related to Opioids Implementation Guide. | PSNet
    psnet.ahrq.gov/issue/reducing-adverse-drug-events-related-opioids-implementation-guide
    August 26, 2015 - Book/Report Reducing Adverse Drug Events Related to Opioids Implementation Guide. … Opioids are high-risk medications that are increasingly problematic for patients and providers. … instructions to help hospitals implement initiatives to improve safe prescribing and administration of opioids … assess processes , identify best practices, and engage staff to reduce adverse events involving opioids … September 16, 2020 Patient Options for Safe and Effective Disposal of Unused Opioids.

33. Spotlight (pdf file)
    psnet.ahrq.gov/sites/default/files/2022-01/final_spotlight_stacked_opioid_administration_01.03.2022.pdf
    January 01, 2022 - • Dose stacking can also occur when a patient receives opioids via numerous sources or routes. … • When administered, naloxone rapidly displaces opioids from μ- receptors and consequently reverses … 28 Thinking Beyond Opioids (1) • Not all discomfort and pain respond to opioids and repeat opioid … Prescribing of opioid analgesics and related mortality before and after the introduction of long- acting … Thinking Beyond Opioids (1) Thinking Beyond Opioids (2) Take Home Points Take-Home Points (1) References

34. Opioids for pain management in older adults: strategies for safe prescribing. | PSNet
    psnet.ahrq.gov/issue/opioids-pain-management-older-adults-strategies-safe-prescribing
    December 09, 2009 - Commentary Opioids for pain management in older adults: strategies for safe prescribing … Opioids for pain management in older adults. … Use of opioids for pain management in older adults can contribute to various problems, including … This commentary discusses the role of nurse practitioners as prescribers of opioids and offers practice … Opioids for pain management in older adults.

35. Wide variation and overprescription of opioids after elective surgery. | PSNet
    psnet.ahrq.gov/issue/wide-variation-and-overprescription-opioids-after-elective-surgery
    September 20, 2017 - Study Classic Wide variation and overprescription of opioids … Wide Variation and Overprescription of Opioids After Elective Surgery. … Nearly all patients were prescribed opioids after elective surgery. … Quantity of opioids prescribed differed by sex, body weight, age, and diagnosis, and there were also … Wide Variation and Overprescription of Opioids After Elective Surgery.

36. Prescription opioid use, misuse, and use disorders in U.S. adults: 2015 National Survey on Drug Use and Health. | PSNet
    psnet.ahrq.gov/issue/prescription-opioid-use-misuse-and-use-disorders-us-adults-2015-national-survey-drug-use-and
    March 30, 2022 - opioids from friends or relatives. … Among those who misused opioids, most did so seeking relief from pain —indicating that untreated pain … September 1, 2021 Opioids and falls risk in older adults: a narrative review. … Insurance, 2017 June 10, 2020 Assessment of potentially inappropriate prescribing of opioid … analgesics requiring prior opioid tolerance.

37. Opioid prescribing after nonfatal overdose and association with repeated overdose: a cohort study. | PSNet
    psnet.ahrq.gov/issue/opioid-prescribing-after-nonfatal-overdose-and-association-repeated-overdose-cohort-study
    June 27, 2018 - More than 90% of patients were prescribed opioids following such events, and within 2 years up to 17% … July 11, 2018 Access to prescription opioids—Primum Non Nocere: a teachable moment. … July 27, 2016 Physician prescribing of opioids to patients at increased risk of overdose … January 12, 2022 Assessment of potentially inappropriate prescribing of opioid analgesics … April 1, 2021 Assessment of potentially inappropriate prescribing of opioid analgesics

38. Association of household opioid availability and prescription opioid initiation among household members. | PSNet
    psnet.ahrq.gov/issue/association-household-opioid-availability-and-prescription-opioid-initiation-among-household
    June 15, 2011 - Opioids are high-risk medications and a significant source of patient harm . … are more likely to initiate prescription opioids. … April 24, 2013 Wide variation and overprescription of opioids after elective surgery. … August 22, 2018 Prescription opioid analgesics commonly unused after surgery: a systematic … April 25, 2018 Opioids and Dentistry.

39. CDC guideline for prescribing opioids for chronic pain—United States, 2016. | PSNet
    psnet.ahrq.gov/issue/cdc-guideline-prescribing-opioids-chronic-pain-united-states-2016
    May 08, 2019 - Organizational Policy/Guidelines CDC guideline for prescribing opioids for chronic … CDC Guideline for Prescribing Opioids for Chronic Pain - United States, 2016. … The authors recommend using opioids for chronic pain only if nonopioid medications and nonpharmacologic … A previous WebM&M commentary describes an adverse event related to opioids. … CDC Guideline for Prescribing Opioids for Chronic Pain - United States, 2016.

40. Opioids in the United Kingdom: safety and surveillance during COVID-19. | PSNet
    psnet.ahrq.gov/issue/opioids-united-kingdom-safety-and-surveillance-during-covid-19
    December 15, 2021 - Review Opioids in the United Kingdom: safety and surveillance during COVID-19. … Opioids in the United Kingdom: safety and surveillance during COVID-19. … Of studies conducted during the pandemic , most explored the impact of the pandemic on access to opioids … Opioids in the United Kingdom: safety and surveillance during COVID-19.