-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/mat-retention-strategies-rapid-review-1.pdf
August 01, 2020 - Participants were still considered
retained in MAT if they continued to use illicit opioids or missed … Unlike naltrexone, buprenorphine
does not require a period of complete abstinence from opioids to initiate … of XR-naltrexone and other antagonist therapies that
require a period of complete abstinence from opioids … Script in a Day intervention for individuals
who are injecting opioids: a feasibility
randomized control … Effects of
medication-assisted treatment on mortality
among opioids users: a systematic review
and
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/scope-communicating-evolving-evidence-white-paper_0.pdf
June 01, 2025 - In the case of opioids,8 serious potential harms include risk of opioid use disorder and overdose. … Opioids Pain Management
Objective Testing Comparisons
Monochromatic Infrared
Photo Energy (MIRE); … of VER-01 to Opioids in Patients
With Chronic Non-specific Low Back Pain
VER-01; Opioid Therapy … CDC
guideline for prescribing opioids for chronic
pain– United States, 2016. … CDC
guideline for prescribing opioids for chronic
pain - United States, 2016.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/hip-fracture-pain_clinician.pdf
May 01, 2011 - effectiveness, benefits, or
adverse events from differing doses, modes of administration, and the
addition of opioids … For example, treatment of moderate to severe
pain may require opioids, which present complications that
-
effectivehealthcare.ahrq.gov/sites/default/files/substance-abuse-horizon-scan-high-impact-1312.pdf
December 01, 2013 - Community-Based Opioid Overdose Prevention Program
(Project Lazarus)
Unmet need: Increased prescribing of opioids … deaths associated with these pharmacologic agents.1 Illegal use of
prescription pain relievers (i.e., opioids … For patients requiring chronic opioids for pain management or
help with opioid dependence, treatment
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-193-disposition-comments-naloxone.pdf
November 27, 2017 - Will that
person keep the pt from using more opioids right
away (since the pt will be dope-sick, but … This is especially relevant because of the
dramatic rise in the abuse of high-potency
opioids such … The urgency is
further heightened by the rapid emergence of
highly potent synthetic opioids, such as … The increased incidence
of high potency opioids involved in an overdose
will make the determination … We deleted the sentence
discussing the proportion
of heroin users who report
prescription opioids
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0215_01-06-2010.pdf
January 01, 2010 - Intervention(s): Dopaminergic agents, antiparkinson agents, benzodiazepines and
other sedative-hypnotics, opioids
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/episodic-migraine-surveillance-report-2.pdf
June 01, 2022 - The original 2020 report examined
the evidence on the comparative effectiveness and harms of opioids … RCTs evaluated
pharmacologic therapies and were included for KQ 2.4-6 There were no new studies on opioids … the original 2020 report and
Surveillance Report 1 on the comparative effectiveness and harms of opioids … Opioids have low or insufficient strength of
evidence for acute treatment of migraine. … SES]); (2) patient medical comorbidities (previous opioid use,
body mass index [BMI]); (3) dose of opioids
-
effectivehealthcare.ahrq.gov/sites/default/files/cer-225-substance-abuse-adolescents-evidence-summary%20225%20Substance%20Use%20Adolescents.pdf
May 01, 2020 - Very few studies evaluated users of opioids, methamphetamines, or substances
other than alcohol or cannabis
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/diabetic-neuropathy-disposition-170707.pdf
March 24, 2017 - In contrast to Griebeler et al., we synthesized
evidence on atypical opioids (tapentadol and
tramadol … Otherwise,
typical opioids are considered to be equivalent
in efficacy for pain and have been treated … HELPFUL
PARTCULATRLY AT NIGHT WITH SLEEP
PROBLEMS; THERE NEEDS TO BE SLOW
TITRATION and atypical opioids … For tramadol and
tapentadol, we report in the abstract that
“opioids have significant long-term risks … and in the discussion, that
“New guidelines and position papers now
recommend against the use of opioids
-
effectivehealthcare.ahrq.gov/sites/default/files/diabetic-neuropathy-disposition-170707.pdf
March 24, 2017 - In contrast to Griebeler et al., we synthesized
evidence on atypical opioids (tapentadol and
tramadol … Otherwise,
typical opioids are considered to be equivalent
in efficacy for pain and have been treated … HELPFUL
PARTCULATRLY AT NIGHT WITH SLEEP
PROBLEMS; THERE NEEDS TO BE SLOW
TITRATION and atypical opioids … For tramadol and
tapentadol, we report in the abstract that
“opioids have significant long-term risks … and in the discussion, that
“New guidelines and position papers now
recommend against the use of opioids
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/nonpharm-treatment-chronic-pain-protocol.pdf
December 11, 2018 - benzodiazepines)
topical agents,(diclofenac, lidocaine capsaicin)
Medical marijuana (any formulation)
Opioid … analgesics
o Key Questions 1-4, 6, subquestion “c”: Exercise
o Key Question 5, 6, subquestion “c” … and CBD); FDA
approved synthetic cannabinoids
(Dronabionol [THC], Nabilone [similar
to THC])
• Opioid … analgesics
KQs 1-4, 6 subquestion c
• Exerciseb
KQ 5, 6 subquestion c
• Biofeedbackc
All KQs: … Efficacy of opioids for chronic pain: a review of the evidence.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-e-surv-rept-1-acute-pain.xlsx
May 29, 2025 - B
Opioid use (mean [SD] tablets): 6.33 (7.1) vs. 5.69 (5.8), p=0.24
Consumed opioids postoperatively: … (1.90) vs. 1.84 (1.29) day 1, p=0.01; 3.14 (2.12) vs. 3.29 (2.14) day 7, p=0.17 NR NR
Escalated to opioids
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cannabis-app-f5-table-surveillance-report-2_0_0.xlsx
May 29, 2025 - discontinuation
49.3% (2650/5373) vs. 72.3% (3887/5373) p<0.001
Estimates of the odds ratio to cease opioids
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/Appendix-E-Table-E5_0.xlsx
May 29, 2025 - discontinuation
49.3% (2650/5373) vs. 72.3% (3887/5373) p<0.001
Estimates of the odds ratio to cease opioids
-
effectivehealthcare.ahrq.gov/products/mhs4-opioid-stewardship/protocol
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0122_06-29-2009.pdf
January 01, 2009 - Comparator(s): no analgesic/anesthetic intervention, analgesia/anesthesia, systemic
medications (such as opioids
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-surveillance-report-3_0.pdf
May 01, 2022 - CDC
guideline for prescribing opioids for chronic
pain– United States, 2016. … CDC
guideline for prescribing opioids for chronic
pain - United States, 2016. … Efficacy of opioids
for chronic pain: a review of the evidence. … Critical
issues on opioids in chronic non-cancer
pain: an epidemiological study. … Opioids for chronic noncancer pain: a
systematic review and meta-analysis.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/pain-chronic_disposition-comments.pdf
September 01, 2011 - Here, it would be “opioids”. … (p.16, L 2-3)
Peer Reviewer
#1
Summary
and
Implications
In addition, the role that opioids … Additionally, the
subheading “Role of opioids” could easily fall under Question 3, the
subheading “ … Peer Reviewer
#5
Summary
and
Implications
The section on opioids does not transition smoothly … Likewise, the immediately following
sections on “role of opioids” and “patient-related issues” appear
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-e-opioid-chronic-pain-surveillance-report-2.xlsx
January 01, 2021 - Table E-1. RCT QA
Table E-1. RCT quality assessment
Author,
Year Randomization Adequate? Allocation Concealment Adequate? Groups Similar at Baseline? Outcome Assessors Masked? Care Provider Masked? Patient Masked? Intention-To-Treat (ITT) Analysis Acceptable Levels of Overall Attrition and Between-Group Differences…
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-e-opioid-chronic-pain-surveillance-report-3.xlsx
January 01, 2021 - Table E-1. RCT QA
Table E-1. RCT quality assessment
Author, Year Randomization Adequate? Allocation Concealment Adequate? Groups Similar at Baseline? Outcome Assessors Masked? Care Provider Masked? Patient Masked? Intention-To-Treat (ITT) Analysis Acceptable Levels of Overall Attrition and Between-Group Differences…