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181. Pharmacotherapy for Adults With Alcohol-Use Disorders in Outpatient Settings: Systematic Review Update (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/alcohol-pharma-final-protocol.pdf
     January 01, 2023 - Endogenous opioids are involved in modulating the expression of alcohol's reinforcing effects. … Endogenous opioids are involved in modulating the expression of alcohol's reinforcing effects. … Crosswalk between DSM-IV dependence and DSM-5 substance use disorders for opioids, cannabis, cocaine

182. Disposition of Comments for CER 183 Tonsillectomy for OSDB (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/tonsillectomy-disposition-170415.pdf
     January 17, 2017 - Peer reviewer #1 Results No mention of opioids for pain management and concerns regarding potentially … We did not identify studies comparing opioids with other agents given in the postoperative period that … Many studies address perioperative use of opioids; however, our KQ did not address perioperative opioid … use given US Food and Drug Administration warnings about use of opioids such as codeine in children

183. App-D-Surv-Report-3-Noninvasive-Nonpharma 0 (xls file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-d-surv-report-3-noninvasive-nonpharma_0.xlsx
     January 01, 2022 - duration of insomnia: 143 vs. 141 vs. 136 months Mean duration of FM: 115 vs. 95 vs. 110 months % taking Opioids … Primary outcomes were yes/no use of sleep medication or opioids. 6 months Mean (SE) A vs. … medication (including NSAIDS, analgesics, selective serotonin releasing agents, anticonvulsants, and opioids

184. Research Protocol: Breast Reconstruction After Mastectomy (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/breast-reconstruction-mastectomy-protocol.pdf
     April 09, 2020 - Research Protocol: Breast Reconstruction After Mastectomy Evidence-based Practice Center Systematic Review Protocol Project Title: Breast Reconstruction After Mastectomy I. Background and Objectives for the Systematic Review Breast cancer is the most common new cancer diagnosis among women and the second …

185. Rapid Evidence Product: Misuse of ADHD Prescription Stimulants in Adults (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/misuse-adhd-prescription-rapid-research.pdf
     July 01, 2025 - Differing Behaviors Around Adult Nonmedical Use of Prescription Stimulants and Opioids: Latent Class … who misused prescriptionstimulants appear similar to users of other hard drugs (e.g., cocaine, opioids … Polysubstance use: Previous year: Opioids 22%, Benzodiazepines 28%, Sleeping medications 15%. … 12.9), Used methamphetamine:2.4% (CI 1.9-3.0), Used heroin 0.6% (0.4-0.7), Misused prescription opioids … , caffeine 47.6%, alcohol 41.8%, cocaine 15.1%, tranquilizers or sedatives 13.3%, prescription opioids

186. Restless-Legs Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/restless-legs_research-protocol.pdf
     December 16, 2011 - Gabapentin Neurontin ® Pregabalin Lyrica ® Opioids Hydrocodone -Vicodin ® -Lortab … Interventions  Pharmacological treatments (dopaminergic agents, sedative-hypnotics, anticonvulsants, opioids

187. Evidence Summary_Comparative Effectiveness Review No. 247_Interventional Treatments for Acute and Chronic Pain: Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-247-interventional-treatments-acute-chronic-pain-evidence-summary_0.pdf
     September 01, 2021 - according to demographic (age, sex, race/ethnicity), clinical (pain severity, pain duration, use of opioids

188. final Fibromyalgia CER protocol_3-31-14 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/fibromyalgia_research-protocol.pdf
     April 03, 2014 - serotonin-reuptake inhibitors such as fluoxetine) o Antiepileptics (such as pregabalin or gabapentin) o Non-opioid … analgesics o Nonsteroidal anti-inflammatory drugs (NSAIDs) o Opioid analgesics o Skeletal muscle … Characteristics of chronic pain patients who take opioids and persistently report high pain intensity

189. Drug Abuse | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/health-topics/drug-abuse

190. AHRQ's Evidence-based Practice Center Division Annual Report 2019: Solving the Puzzle for Evidence-Based Decision Making (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/pdf/epc-year-in-review-2019.pdf
     January 01, 2019 - AHRQ's Evidence-based Practice Center Division Annual Report 2019: Solving the Puzzle for Evidence-Based Decision Making AHRQ’s Evidence-based Practice Center Divison Annual Report 2019 Solving the Puzzle for Evidence-Based Decision Making e Evidence-based Practice Center Program 2019 Year in Review EPC Missi…

191. Research White Paper - Assessing the Predictive Validity of Strength of Evidence Grades: A Meta-Epidemiological Study (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/grades-predictive-values_white-paper.pdf
     September 01, 2015 - 201237 Surgical therapy of anal fissure and healing 979 OR: 0.11 (0.06 to 0.23) Nüesch et al., 201038 Opioids … Oral or transdermal opioids for osteoarthritis of the knee or hip.

192. Methods White Paper: Improving the Utility of Evidence Synthesis for Decision Makers in the Face of Insufficient Evidence (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/improving-utility-evidence-synthesis-white-paper.pdf
     April 01, 2021 - Comparisons regimens for ceasing opioids 5.

193. Chronic-Cough Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/chronic-cough_executive.pdf
     March 01, 2014 - 1 Comparative Effectiveness Review Number 100 Assessment and Management of Chronic Cough Executive Summary Background In the United States, cough is the most common complaint for which patients seek medical attention and is the second most common reason for a general medical examination, accounting for …

194. Prescription Drug Abuse | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/health-topics/prescription-drug-abuse

195. Pharmacotherapy for Adults With Alcohol Use Disorder in Outpatient Settings (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/alcohol-misuse-drug-therapy_policymaker.pdf
     August 01, 2016 - Pharmacotherapy for Adults With Alcohol Use Disorder in Outpatient Settings B A C K G R O U N D Alcohol use disorder (AUD) includes harmful use of alcohol, alcohol abuse, and alcohol dependence. In the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5), alcohol abuse and alcohol de…

196. Treatments, Technologies, and Models for Management of Acute and Chronic Pain in People With a History of Substance Use Disorder | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/pain-management-substance-abuse/research

197. Treatment for Restless Legs Syndrome Disposition of Comments Report (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/restless-legs_disposition-comments.pdf
     November 27, 2012 - Peer Reviewer #1 Results Pg 26 (line 38), pg 82 (line 48): With respect to opioids, the text reads … tolerability and durability,” it is stated that augmentation is believed not to occur with gabapentin or opioids

198. Effectiveness of Treatments for Diabetic Peripheral Neuropathy (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/diabetic-neuropathy_research-protocol.pdf
     May 09, 2016 - antidepressants and anticonvulsants, tramadol, and capsaicin recommended as probably effective, as well as opioids … , levitiracetam, oxcarbazepine, sodium valproate, tiagabine, topiramate, zonisamide) Analgesics Opioids

199. Evaluation of Mental Health Applications (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/mental-health-app-protocol-updated.pdf
     January 01, 2018 - Evaluation of Mental Health Applications Evidence-based Practice Center Technical Brief Protocol Project Title: Evaluation of Mental Health Applications I. Background and Objectives for the Technical Brief Among adults aged 18 or older in the U.S., the prevalence of mental illnesses has increased fr…

200. March 3rd Impact of Healthcare Algorithms on Racial and Ethnic Disparities in Healthcare (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/impact-healthcare-algorithms-racial-ethnic-disparities-March-3.pdf
     July 01, 2023 - March 3rd Impact of Healthcare Algorithms on Racial and Ethnic Disparities in Healthcare Impact of Healthcare Algorithms on Racial and Ethnic Disparities in Health and Healthcare March 3, 2023 10:00 a.m.- 2:00 p.m. ET Welcome Prashila Dullabh, MD NORC Racial Bias and Healthcare Algorithms …