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  1. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cannabis-2022-surv-rep-4-tables-F1-4.xlsx
    January 01, 2022 - 13 NR NR NR NR NR NR NR Patients with major psychiatric disorder or past drug/alcohol abuse excluded Opioids … abdominal pain Excluded daily cannabis use in past 3 years Mean 53 50 96 2 NR 2 NR NR NR Excluded Weak opioids … : 21/50 Strong opioids: 26/50 65 50 THC oral tablet (Dronabinol): days 1 to 5: 3 mg 3 times/d; days 6 … psoriatic arthritis Previous CBD use: 18% Median 62 44 NR NR NR NR NR NR NR NR Concomitant medicine: Opioids … with severe psychiatric diseases (severe depression and schizophrenia) excluded Concomitant use of opioids
  2. effectivehealthcare.ahrq.gov/sites/default/files/pdf/epc-health-care-practice-delivery.pdf
    November 01, 2022 - AHRQ’s Evidence-based Practice Center Program: Synthesizing evidence to improve health care practice and delivery What Is the Agency for Healthcare Research and Quality (AHRQ) Evidence-based Practice Center Program? AHRQ is the lead Federal Agency within the U.S. Department of Health and Human Services that is char…
  3. effectivehealthcare.ahrq.gov/products/treatments-acute-pain/research
  4. #14 SUBSTANCE ABUSE (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/substance-abuse-horizon-scan-high-impact-1512.pdf
    December 01, 2015 - #14 SUBSTANCE ABUSE AHRQ Healthcare Horizon Scanning System – Potential High-Impact Interventions Report Priority Area 14: Substance Abuse Prepared for: Agency for Healthcare Research and Quality U.S. Department of Health and Human Services 5600 Fishers Lane Rockville, MD 20857 www.ahr…
  5. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cannabis-2022-surv-rep-3-tables-F1-4.xlsx
    January 01, 2022 - abdominal pain Excluded daily cannabis use in past 3 years Mean 53 50 96 2 NR 2 NR NR NR Excluded Weak opioids … : 21/50 Strong opioids: 26/50 65 50 THC oral tablet (Dronabinol): days 1 to 5: 3 mg 3 times/d; days 6 … with a personal or family history of schizophrenia or psychotic disorders excluded Previous treatment opioids … psoriatic arthritis Previous CBD use: 18% Median 62 44 NR NR NR NR NR NR NR NR Concomitant medicine: Opioids … with severe psychiatric diseases (severe depression and schizophrenia) excluded Concomitant use of opioids
  6. effectivehealthcare.ahrq.gov/products/retention-strategies-opioid-use-disorder/rapid-protocol
  7. effectivehealthcare.ahrq.gov/sites/default/files/pdf/transparency-neuropathy_research.pdf
    March 01, 2018 - Studies comparing atypical opioids with placebo identified through ClinicalTrials.gov, published literature … For another two comparisons (lacosamide versus placebo and atypical opioids versus placebo), we found … No effect No effect Atypical opioids vs. … CT.gov = ClinicalTrials.gov; RCT = randomized controlled trial 34 Atypical Opioids Versus … Studies comparing atypical opioids with placebo identified through ClinicalTrials.gov, published literature
  8. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-254-rural-telehealth-executive-summary.pdf
    December 01, 2022 - Executive Summary_Comparative Effectiveness Review No. 254: Improving Rural Health Through Telehealth-Guided Provider-to-Provider Communication Comparative Effectiveness Review Number 254 Improving Rural Health Through Telehealth-Guided Provider-to-Provider Communication Executive Summary Main Points • Use …
  9. effectivehealthcare.ahrq.gov/sites/default/files/pdf/alcohol-misuse-drug-therapy_research-protocol.pdf
    January 27, 2012 - Opioid antagonist; competitively binds to opioid receptors and may block the effects of endogenous opioids
  10. effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-d-surv-report-1-noninvasive-nonpharma_0.xlsx
    January 01, 2021 - duration of insomnia: 143 vs. 141 vs. 136 months Mean duration of FM: 115 vs. 95 vs. 110 months % taking Opioids … Primary outcomes were yes/no use of sleep medication or opioids. 6 months Mean (SE) A vs. … medication (including NSAIDS, analgesics, selective serotonin releasing agents, anticonvulsants, and opioids
  11. effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-d-surv-report-2-noninvasive-nonpharma.xlsx
    January 01, 2021 - duration of insomnia: 143 vs. 141 vs. 136 months Mean duration of FM: 115 vs. 95 vs. 110 months % taking Opioids … Primary outcomes were yes/no use of sleep medication or opioids. 6 months Mean (SE) A vs. … medication (including NSAIDS, analgesics, selective serotonin releasing agents, anticonvulsants, and opioids
  12. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-2024-surv-rep-update-tables-e1-4.xlsx
    January 01, 2024 - 13 NR NR NR NR NR NR NR Patients with major psychiatric disorder or past drug/alcohol abuse excluded Opioids … abdominal pain Excluded daily cannabis use in past 3 years Mean 53 50 96 2 NR 2 NR NR NR Excluded Weak opioids … : 21/50 Strong opioids: 26/50 65 50 THC oral tablet (Dronabinol): days 1 to 5: 3 mg 3 times/d; days 6 … psoriatic arthritis Previous CBD use: 18% Median 62 44 NR NR NR NR NR NR NR NR Concomitant medicine: Opioids … with severe psychiatric diseases (severe depression and schizophrenia) excluded Concomitant use of opioids
  13. effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs-IV-rapid-response-deprescribing.pdf
    February 01, 2024 - clinics, acute care hospitals, long-term care Age ≥65 years and taking benzodiazepi nes and/or opioids … • decreased benzodiazepines and/or opioids, with variable effect for different interventions … Pharmacist interventions to deprescribe opioids and benzodiazepines in older adults: A rapid review
  14. effectivehealthcare.ahrq.gov/sites/default/files/pdf/restless-legs-future_research.pdf
    February 01, 2013 - No eligible studies assessed opioids, sedative hypnotics, or tramadol, though these are used for RLS … No eligible studies assessed opioids, sedative hypnotics, or tramadol, though these are used clinically … What is the effectiveness of other drugs that are not dopamine agonists or alpha 2 ligands (e.g., opioids … What is the effectiveness of other drugs that are not dopamine agonists or alpha 2 ligands (e.g., opioids … What is the effectiveness of other drugs that are not dopamine agonists or alpha 2 ligands (e.g. opioids
  15. effectivehealthcare.ahrq.gov/sites/default/files/pdf/labor-nitrous-oxide_research-protocol.pdf
    August 24, 2011 - Alternatives/comparators to nitrous oxide include: epidural analgesia/anesthesia; systemic drugs such as opioids … include, but are not limited to, epidural analgesia, paracervical block, pudendal block, and parenteral opioids
  16. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-2025-surv-rep-update-tables-e1-4.xlsx
    January 01, 2025 - 13 NR NR NR NR NR NR NR Patients with major psychiatric disorder or past drug/alcohol abuse excluded Opioids … abdominal pain Excluded daily cannabis use in past 3 years Mean 53 50 96 2 NR 2 NR NR NR Excluded Weak opioids … : 21/50 Strong opioids: 26/50 65 50 THC oral tablet (Dronabinol): days 1 to 5: 3 mg 3 times/d; days 6 … psoriatic arthritis Previous CBD use: 18% Median 62 44 NR NR NR NR NR NR NR NR Concomitant medicine: Opioids … with severe psychiatric diseases (severe depression and schizophrenia) excluded Concomitant use of opioids
  17. Untitled (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/pdf/suicide-prevention_research-protocol.pdf
    December 23, 2015 - Untitled Source: www.effectivehealthcare.ahrq.gov Published online: December 23, 2015 Evidence-based Practice Center Systematic Review Protocol Project Title: Suicide Prevention I. Background and Objectives for the Systematic Review Despite advances in the diagnosis and treatment of major mental disord…
  18. effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/alcohol-pharma-final-protocol.pdf
    January 01, 2023 - Endogenous opioids are involved in modulating the expression of alcohol's reinforcing effects. … Endogenous opioids are involved in modulating the expression of alcohol's reinforcing effects. … Crosswalk between DSM-IV dependence and DSM-5 substance use disorders for opioids, cannabis, cocaine
  19. effectivehealthcare.ahrq.gov/products/arthritis-analgesics-safety/research
  20. effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-d-surv-report-3-noninvasive-nonpharma_0.xlsx
    January 01, 2022 - duration of insomnia: 143 vs. 141 vs. 136 months Mean duration of FM: 115 vs. 95 vs. 110 months % taking Opioids … Primary outcomes were yes/no use of sleep medication or opioids. 6 months Mean (SE) A vs. … medication (including NSAIDS, analgesics, selective serotonin releasing agents, anticonvulsants, and opioids

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