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effectivehealthcare.ahrq.gov/products/retention-strategies-opioid-use-disorder/rapid-research
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effectivehealthcare.ahrq.gov/products/emt-naloxon/systematic-review
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effectivehealthcare.ahrq.gov/sites/default/files/hip-fracture-pain_surveillance.pdf
July 08, 2015 - Opioid analgesics and the
risk of fractures in older adults with arthritis. … ;RESULTS: Of the 236 participants, 66 (28%) had dementia, and 213 (90%) received opioids
postoperatively
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effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/impact-healthcare-algorithms-racial-ethnic-disparities-March-2.pdf
May 15, 2023 - Opioid Safety
76
STORM: Family of Decision Support Tools to Support
Safe Care of Patients Exposed to Opioids … • In 2021, PERC applied the framework to STORM-2 (2014-1015)
• STORM-2 is three models:
► No opioids … in the observation window
► Discontinued during the observation window
► Actively on opioids on the
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/restless-legs_executive.pdf
November 01, 2012 - • No eligible studies assessed opioids, sedative
hypnotics, or tramadol, though these are used clinically … Data were available for
gabapentin (one study), opioids (multiple opioids, one
study; methadone, one … • Many classes of drugs used in clinical
practice such as opioids and sedative
hypnotics have not … • Randomized trials of classes of drugs other than
dopamine agonists, such as opioids and sedative … Long-term
follow-up on restless legs syndrome patients treated with opioids.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/copd-research-protocol.pdf
April 11, 2018 - in the treatment of stable COPD, include mucolytics, PDE4 inhibitors, and symptom
palliation with opioids … The role of treatments that can
relieve breathlessness including opioids and benzodiazepines in patients … anticholinergic agents
o Inhaled and systemic corticosteroid therapy
o Antibiotics
o Mucolytics
o Opioids … Anticholinergic agents
• Glucocorticoid therapy
• Antibiotics
• Mucolytics
• PDE4 Inhibitors
• Opioids
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effectivehealthcare.ahrq.gov/products/retention-strategies-opioid-use-disorder
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effectivehealthcare.ahrq.gov/products/collections/improving-pain-management
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/alcohol-misuse-drug-therapy_clinician.pdf
February 01, 2016 - Opioid antagonist that competitively binds
to opioid receptors and blocks the effects of
endogenous opioids
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/horizon-scan_research-2015.pdf
January 01, 2015 - be driven by clinicians prescribing Evzio to patients concurrently with prescribing
higher doses of opioids … for long-trerm pain relief, patients known to abuse opioids, or
people known to be in close contact … impact of prescribing a naloxone auto-injector for use in the event of overdose in
persons prescribed opioids … We limit our model to prescribed opioids for two reasons: (1) a person using opioids
without a prescription … naloxone kit and (2) a
clear majority of deaths from opioid overdose occur in people with prescribed opioids
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-234-headaches-pregnancy-summary.pdf
November 01, 2020 - Treatment—antiemetics (dopamine receptor antagonists), antihistamines, and
opioids: One RCT found that
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cannabis-app-f1-f4-tables-surveillance-report-2_0_0.xlsx
May 29, 2025 - abdominal pain Excluded daily cannabis use in past 3 years Mean 53 50 96 2 NR 2 NR NR NR Excluded Weak opioids … : 21/50
Strong opioids: 26/50 65 50 THC oral tablet (Dronabinol): days 1 to 5: 3 mg 3 times/d; days 6 … with a personal or family history of schizophrenia or psychotic disorders excluded Previous treatment opioids … analgesics during the study; 19% took natural opium alkaloids (such as dihydrocodeine) and 18% other opioids … psoriatic arthritis Previous CBD use: 18% Median 62 44 NR NR NR NR NR NR NR NR Concomitant medicine:
Opioids
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/lumbar-fusion-draft-report-appendix-d.xlsx
January 01, 2019 - Data reported in Friedly 2019 Opioids: 21% Central spinal stenosis NR 100% neurogenic claudication ( … B
In patients that received opioids at baseline
RDQ (0-24; higher = worse), mean (IQR)
Baseline: 17.3 … were reported with deteriorating relief below 50%
Data NR NR Most patients received opioid and non-opioid … analgesics, adjuvant analgesics, and some were involved in therapeutic exercise programs. … and/or non-opioid analgesics, adjuvant alagesics, and some were involved in therapeutic exercise programs
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cannabis-2022-update-surv-rep-1-app-F1-4.xlsx
January 01, 2022 - abdominal pain Excluded daily cannabis use in past 3 years Mean 53 50 96 2 NR 2 NR NR NR Excluded Weak opioids … : 21/50
Strong opioids: 26/50 65 50 THC oral tablet (Dronabinol): days 1 to 5: 3 mg 3 times/d; days 6 … with a personal or family history of schizophrenia or psychotic disorders excluded Previous treatment opioids … analgesics during the study; 19% took natural opium alkaloids (such as dihydrocodeine) and 18% other opioids … psoriatic arthritis Previous CBD use: 18% Median 62 44 NR NR NR NR NR NR NR NR Concomitant medicine:
Opioids
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-tables-e1-e4-2022-update_0.xlsx
January 01, 2022 - abdominal pain Excluded daily cannabis use in past 3 years Mean 53 50 96 2 NR 2 NR NR NR Excluded Weak opioids … : 21/50
Strong opioids: 26/50 65 50 THC oral tablet (Dronabinol): days 1 to 5: 3 mg 3 times/d; days 6 … with a personal or family history of schizophrenia or psychotic disorders excluded Previous treatment opioids … analgesics during the study; 19% took natural opium alkaloids (such as dihydrocodeine) and 18% other opioids … psoriatic arthritis Previous CBD use: 18% Median 62 44 NR NR NR NR NR NR NR NR Concomitant medicine:
Opioids
-
effectivehealthcare.ahrq.gov/products/opioid-use-disorder/technical-brief
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/alcohol-misuse-drug-therapy_executive.pdf
January 27, 2012 - Naltrexone Opioid antagonist; competitively binds to
opioid receptors and blocks the effects of
endogenous opioids … hepatitis or liver failure (and has precautions for other
hepatic disease) and for those currently using opioids … or
with anticipated need for opioids, and it can precipitate
severe withdrawal for patients dependent … on opioids.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/Appendix-E-Evidence-Tables-E1-E4_0.xlsx
May 29, 2025 - schizophrenia, psychosis, severe personality disorder, and current suicidal ideation) excluded Previous use of opioids … abdominal pain Excluded daily cannabis use in past 3 years Mean 53 50 96 2 NR 2 NR NR NR Excluded Weak opioids … : 21/50
Strong opioids: 26/50 65 50 THC oral tablet (Dronabinol): days 1 to 5: 3 mg 3 times/d; days 6 … with a personal or family history of schizophrenia or psychotic disorders excluded Previous treatment opioids … analgesics during the study; 19% took natural opium alkaloids (such as dihydrocodeine) and 18% other opioids
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cannabis-2023-surv-rep-1-app-F.xlsx
January 01, 2023 - 13 NR NR NR NR NR NR NR Patients with major psychiatric disorder or past drug/alcohol abuse excluded Opioids … abdominal pain Excluded daily cannabis use in past 3 years Mean 53 50 96 2 NR 2 NR NR NR Excluded Weak opioids … : 21/50
Strong opioids: 26/50 65 50 THC oral tablet (Dronabinol): days 1 to 5: 3 mg 3 times/d; days 6 … psoriatic arthritis Previous CBD use: 18% Median 62 44 NR NR NR NR NR NR NR NR Concomitant medicine:
Opioids … with severe
psychiatric diseases (severe depression and schizophrenia) excluded Concomitant use of opioids
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cannabis-2023-surv-rep-4-tables-E-1-E-4.xlsx
January 01, 2023 - 13 NR NR NR NR NR NR NR Patients with major psychiatric disorder or past drug/alcohol abuse excluded Opioids … abdominal pain Excluded daily cannabis use in past 3 years Mean 53 50 96 2 NR 2 NR NR NR Excluded Weak opioids … : 21/50
Strong opioids: 26/50 65 50 THC oral tablet (Dronabinol): days 1 to 5: 3 mg 3 times/d; days 6 … psoriatic arthritis Previous CBD use: 18% Median 62 44 NR NR NR NR NR NR NR NR Concomitant medicine:
Opioids … with severe
psychiatric diseases (severe depression and schizophrenia) excluded Concomitant use of opioids