-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-d-opioid-chronic-pain-surveillance-report-3.xlsx
September 30, 2015 - n=290
A: Involuntary opioid reduction (n=88)
B: Voluntary opioid reduction (n=96)
C: No opioid reduction … ≥65 years on long-term opioid therapy ≥ with new long-term opioid therapy use episode, continuously … use (n=634)
B: Intermittent opioid use (n=746)
C: No opioid use (n=2,792) Age, years
18 to 39: 6.3% … use collected in 5 interview rounds over 2 years
A) Persistent opioid use: opioid use reported in 2 … consecutive rounds before the last round of followup
B) Intermittent opioid use: opioid use reported
-
effectivehealthcare.ahrq.gov/products/opioids-chronic-pain
February 27, 2019 - Opioid Treatments for Chronic Pain
Timeline
February 22, 2019
Topic Initiated … February 27, 2019
Research Protocol
Opioid Treatments for Chronic … Pain
April 16, 2020
Systematic Review
Opioid Treatments for Chronic
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effectivehealthcare.ahrq.gov/products/retention-strategies-opioid-use-disorder/www.ncbi.nlm.nih.gov/pubmed
September 23, 2021 - Products »
Retention Strategies for Medications for Addiction Treatment (MAT) in Adults with Opioid … Questions
Draft
April 14, 2021
Improving Pain Management in the Context of America's Opioid
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/appendixes-surveillance-report-1.pdf
September 30, 2021 - /
10. opioid*.ti,ab,kw.
11. … strategy [3a], short-acting opioid [3b], long-acting
opioid [3c], short plus long-acting opioid [3d … , long-acting opioid
[3b], alternative long-acting opioid [3c], long-acting
opioid alone [3d], as-needed … opioid therapy. … Trajectories of Opioid Use Following First
Opioid Prescription in Opioid-Naive Youths
and Young Adults
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/topic-brief3-SUD.pdf
April 01, 2021 - long-acting opioid agonist methadone,
the partial opioid agonist buprenorphine, or the opioid antagonist … In patients with pain and co-occurring
opioid use disorder, treatment with medications for opioid use … disorder with full or partial opioid
agonist effects (methadone or buprenorphine) or opioid antagonist … , non-pharmacologic therapies, and non-
opioid medications for chronic pain and opioid use disorder; … with opioid use disorder.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/topic-brief3-SUD.pdf
April 01, 2021 - long-acting opioid agonist methadone,
the partial opioid agonist buprenorphine, or the opioid antagonist … In patients with pain and co-occurring
opioid use disorder, treatment with medications for opioid use … disorder with full or partial opioid
agonist effects (methadone or buprenorphine) or opioid antagonist … , non-pharmacologic therapies, and non-
opioid medications for chronic pain and opioid use disorder; … with opioid use disorder.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-e-opioid-chronic-pain-surveillance-report-3.xlsx
January 01, 2021 - Table E-1. RCT QA
Table E-1. RCT quality assessment
Author, Year Randomization Adequate? Allocation Concealment Adequate? Groups Similar at Baseline? Outcome Assessors Masked? Care Provider Masked? Patient Masked? Intention-To-Treat (ITT) Analysis Acceptable Levels of Overall Attrition and Between-Group Differences…
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-e-opioid-chronic-pain-surveillance-report-2.xlsx
January 01, 2021 - Table E-1. RCT QA
Table E-1. RCT quality assessment
Author,
Year Randomization Adequate? Allocation Concealment Adequate? Groups Similar at Baseline? Outcome Assessors Masked? Care Provider Masked? Patient Masked? Intention-To-Treat (ITT) Analysis Acceptable Levels of Overall Attrition and Between-Group Differences…
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-e-opioid-chronic-pain-surveill-report-1.xlsx
January 01, 2021 - Table E-1. RCT QA
Table E-1. RCT quality assessment
Author,
Year Randomization Adequate? Allocation Concealment Adequate? Groups Similar at Baseline? Outcome Assessors Masked? Care Provider Masked? Patient Masked? Intention-to-Treat (ITT) Analysis Acceptable Levels of Overall Attrition and Between-Group Differences…
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/mat-retention-strategies-rapid-review-1.pdf
August 01, 2020 - without decreased opioid tolerance. … Effect of Buprenorphine Implants on Illicit
Opioid Use Among Abstinent Adults With
Opioid Dependence … Medication for Opioid Use Disorder After
Nonfatal Opioid Overdose and Association
With Mortality: A … treatment, Medication-
assisted therapy, opioid, opioids, opioid use disorder, retention, retention, … Effect of Buprenorphine Implants on Illicit
Opioid Use Among Abstinent Adults With
Opioid Dependence
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/emt-naloxon_research-protocol.pdf
November 29, 2016 - Aversive and reinforcing opioid effects:
a pharmacogenomic twin study. … Association between opioid prescribing
patterns and opioid overdose-related deaths. … Opioid prescriptions for chronic pain
and overdose: a cohort study. … Management of opioid analgesic overdose. … FDA approves new hand-held auto-injector to reverse opioid overdose.
-
effectivehealthcare.ahrq.gov/sites/default/files/substance-abuse-horizon-scan-high-impact-1406.pdf
January 01, 2020 - opioid abuse treatment. … overdoses: opioid misuse
and dependence. … Prescription
opioid abuse in chronic pain: a review of opioid
abuse predictors and strategies to … curb opioid
abuse. … Responding to opioid overdose. [internet].
-
effectivehealthcare.ahrq.gov/products/acute-pain-ems/research
September 03, 2019 - Combining an opioid with ketamine may be more effective in reducing pain compared with opioids alone. … To assess comparative effectiveness and harms of opioid and nonopioid analgesics administered by emergency … The combined use of an opioid and ketamine, administered primarily IV, may reduce pain more than an opioid … Evidence on comparative effects of nitrous oxide and on harms of combined opioid and ketamine is insufficient … Combined administration of an opioid and ketamine may reduce acute pain more than an opioid alone, but
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/main-apps-surv-report-2-acute-pain.pdf
May 01, 2022 - use of prescribing opioid therapy
for acute pain conditions; and factors influencing opioid prescribing … (or/1-4) and (5 or 6)
8. exp Analgesics, Opioid/
9. opioid*.ti,ab,kw.
10. … (or/1-4) and (5 or 6)
8. exp Analgesics, Opioid/
9. opioid*.ti,ab,kw.
10. … for predicting risk of opioid misuse, opioid use disorder, or
overdose? … for predicting risk of opioid misuse, opioid use disorder,
or overdose?
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/chronic-pain-opioid-treatment_disposition-comments.pdf
September 29, 2014 - The Effectiveness and Risks of Long-Term Opioid
Treatment of Chronic Pain. … Tapentadol was included
because it is a much stronger opioid
agonist. … formulas in reducing opioid abuse. … Emergency department visits among recipients of chronic opioid therapy. … Association between opioid prescribing patterns and opioid overdose-related
deaths.Bohnert AS, Valenstein
-
effectivehealthcare.ahrq.gov/products/treatments-acute-pain/protocol
January 02, 2020 - Opioid prescribing quadrupled from 1999 to 2010; concurrently, the number of opioid analgesics deaths … used; (4) the duration of opioid therapy; (5) opioid use history; or (6) substance use history? … for predicting risk of opioid misuse, opioid use disorder, or overdose? … for predicting risk of opioid misuse, opioid use disorder, or overdose? … (or/1-4) and (5 or 6)
exp Analgesics, Opioid/
opioid*.ti,ab,kw.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/surveillance-report-1-treatments-for-acute-pain.pdf
January 01, 2022 - evaluated an opioid alone. … (or/1-4) and (5 or 6)
8. exp Analgesics, Opioid/
9. opioid*.ti,ab,kw.
A-6
10. … (or/1-4) and (5 or 6)
8. exp Analgesics, Opioid/
9. opioid*.ti,ab,kw.
10. … for predicting risk of opioid misuse, opioid use disorder, or overdose? … for predicting risk of opioid misuse, opioid use disorder, or overdose?
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/main-apps-surv-rept-1-acute-pain.pdf
May 01, 2022 - evaluated an opioid alone. … (or/1-4) and (5 or 6)
8. exp Analgesics, Opioid/
9. opioid*.ti,ab,kw.
A-6
10. … (or/1-4) and (5 or 6)
8. exp Analgesics, Opioid/
9. opioid*.ti,ab,kw.
10. … for predicting risk of opioid misuse, opioid use disorder, or
overdose? … for predicting risk of opioid misuse, opioid use disorder,
or overdose?
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/ehc-protocol-acute-pain-treatments.pdf
August 08, 2019 - Opioid prescribing quadrupled from 1999 to 2010; concurrently, the number of opioid
analgesics deaths … used; (4) the duration of opioid
therapy; (5) opioid use history; or (6) substance use history? … for predicting risk of opioid misuse, opioid use disorder, or overdose? … for predicting risk of opioid misuse, opioid use disorder, or overdose? … (or/1-4) and (5 or 6)
8. exp Analgesics, Opioid/
9. opioid*.ti,ab,kw.
10.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/peripheral-nerve-block-key-questions.pdf
May 09, 2019 - Strategies may
include opioid or non-opioid analgesics (e.g., NSAIDs, acetaminophen), regional
anesthesia … Opioid use
7. Health related quality of life
8. Patient satisfaction
• Long-term outcomes
1. … Opioid use
5. Health related quality of life
6. Patient satisfaction
• Harms
1. … Incidence of and Risk Factors for Chronic
Opioid Use Among Opioid-Naive Patients in the Postoperative … Opioid-
Prescribing Guidelines for Common Surgical Procedures: An Expert Panel Consensus.