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21. App-E-Opioid-Chronic-Pain-Surveillance-Report-2 (xls file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-e-opioid-chronic-pain-surveillance-report-2.xlsx
    January 01, 2021 - Table E-1. RCT QA Table E-1. RCT quality assessment Author, Year Randomization Adequate? Allocation Concealment Adequate? Groups Similar at Baseline? Outcome Assessors Masked? Care Provider Masked? Patient Masked? Intention-To-Treat (ITT) Analysis Acceptable Levels of Overall Attrition and Between-Group Differences…

22. App-E-Opioid-Chronic-Pain-Surveill-Report-1 (xls file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-e-opioid-chronic-pain-surveill-report-1.xlsx
    January 01, 2021 - Table E-1. RCT QA Table E-1. RCT quality assessment Author, Year Randomization Adequate? Allocation Concealment Adequate? Groups Similar at Baseline? Outcome Assessors Masked? Care Provider Masked? Patient Masked? Intention-to-Treat (ITT) Analysis Acceptable Levels of Overall Attrition and Between-Group Differences…

23. Systematic Review on Opioid Treatments for Chronic Pain: Surveillance Report 2 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/opioid-chronic-pain-surveillance-report-2.pdf
    April 01, 2022 - / 10. opioid*.ti,ab,kw. 11. … strategy [3a], short-acting opioid [3b], long-acting opioid [3c], short plus long-acting opioid [3d … , long-acting opioid [3b], alternative long-acting opioid [3c], long-acting opioid alone [3d], as-needed … opioid therapy. … Trajectories of Opioid Use Following First Opioid Prescription in Opioid-Naive Youths and Young Adults

24. Systematic Review on Opioid Treatments for Chronic Pain: Surveillance Report 1 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/opioids-chronic-pain-surveillance-report-1-final.pdf
    April 01, 2022 - opioid therapy. … strategy [3a], short-acting opioid [3b], long-acting opioid [3c], short plus long-acting opioid [3d … , long-acting opioid [3b], alternative long-acting opioid [3c], long-acting opioid alone [3d], as-needed … opioid therapy. … Trajectories of Opioid Use Following First Opioid Prescription in Opioid-Naive Youths and Young Adults

25. Systematic Review on Opioid Treatments for Chronic Pain: Surveillance Report 3 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/opioid-chronic-pain-surveillance-report-3.pdf
    June 01, 2022 - The observational study compared involuntary opioid reduction, voluntary opioid reduction, and no opioid … strategy [3a], short-acting opioid [3b], long-acting opioid [3c], short plus long-acting opioid [3d … , long-acting opioid [3b], alternative long-acting opioid [3c], long-acting opioid alone [3d], as-needed … opioid abuse. … Trajectories of Opioid Use Following First Opioid Prescription in Opioid-Naive Youths and Young Adults

26. Opioid Treatments for Chronic Pain | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/opioids-chronic-pain/research

27. The Effectiveness and Risks of Long-Term Opioid Treatment of Chronic Pain (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/chronic-pain-opioid-treatment_executive.pdf
    September 19, 2014 - characteristics (e.g., specific opioid, short- versus long-acting opioid, mode of administration, dose … In patients with chronic pain, what are the risks of opioids versus placebo or no opioid on: (1) opioid … In patients on long-term opioid therapy, what are the effects of decreasing opioid doses or of tapering … Association between opioid prescribing patterns and opioid overdose- related deaths. … Opioid Misuse Measure (COMM).

28. The Effectiveness and Risks of Long-term Opioid Treatment of Chronic Pain | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/chronic-pain-opioid-treatment/research-protocol

29. Management of Suspected Opioid Overdose With Naloxone by Emergency Medical Services Personnel - Executive Summary (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-193-naloxone-executive-summary.pdf
    November 01, 2017 - repeat opioid overdose episodes. … FDA approves new hand-held auto-injector to reverse opioid overdose. … Management of opioid analgesic overdose. … Community management of opioid overdose. … Out-of-hospital treatment of opioid overdoses in an urban setting.

30. Topic-Brief3-Sud (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/topic-brief3-SUD.pdf
    April 01, 2021 - long-acting opioid agonist methadone, the partial opioid agonist buprenorphine, or the opioid antagonist … In patients with pain and co-occurring opioid use disorder, treatment with medications for opioid use … disorder with full or partial opioid agonist effects (methadone or buprenorphine) or opioid antagonist … , non-pharmacologic therapies, and non- opioid medications for chronic pain and opioid use disorder; … with opioid use disorder.

31. Topic-Brief3-Sud (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/topic-brief3-SUD.pdf
    April 01, 2021 - long-acting opioid agonist methadone, the partial opioid agonist buprenorphine, or the opioid antagonist … In patients with pain and co-occurring opioid use disorder, treatment with medications for opioid use … disorder with full or partial opioid agonist effects (methadone or buprenorphine) or opioid antagonist … , non-pharmacologic therapies, and non- opioid medications for chronic pain and opioid use disorder; … with opioid use disorder.

32. Management of suspected opioid overdose with Naloxone by Emergency Medical Services personnel (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/emt-naloxon_research-protocol.pdf
    November 29, 2016 - Aversive and reinforcing opioid effects: a pharmacogenomic twin study. … Association between opioid prescribing patterns and opioid overdose-related deaths. … Opioid prescriptions for chronic pain and overdose: a cohort study. … Management of opioid analgesic overdose. … FDA approves new hand-held auto-injector to reverse opioid overdose.

33. Retention Strategies for Medications for Addiction Treatment (MAT) in Adults with Opioid Use Disorder | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/retention-strategies-opioid-use-disorder

34. Medication-Assisted Treatment Models of Care for Opioid Use Disorder in Primary Care Settings | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/opioid-use-disorder/technical-brief

35. Retention Strategies for Medications for Addiction Treatment in Adults With Opioid Use Disorder: A Rapid Evidence Review (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/mat-retention-strategies-rapid-review-1.pdf
    August 01, 2020 - without decreased opioid tolerance. … Effect of Buprenorphine Implants on Illicit Opioid Use Among Abstinent Adults With Opioid Dependence … Medication for Opioid Use Disorder After Nonfatal Opioid Overdose and Association With Mortality: A … treatment, Medication- assisted therapy, opioid, opioids, opioid use disorder, retention, retention, … Effect of Buprenorphine Implants on Illicit Opioid Use Among Abstinent Adults With Opioid Dependence

36. Executive Summary: Peripheral Nerve Blocks for (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/peripheral-nerve-blocks-final-exec-sum.pdf
    August 01, 2025 - associated with significant adverse effects, including the risk of long-term dependence or chronic opioid … CWB decreased opioid consumption with small benefit in pain scores (low SOE). … In open cardiac surgery, CWBs showed some benefit in reducing pain and opioid use (low SOE). … Incidence of and Risk Factors for Chronic Opioid Use Among Opioid-Naive Patients in the Postoperative … Chronic Opioid Use after Surgery: Implications for Perioperative Management in the Face of the Opioid

37. #14 SUBSTANCE ABUSE (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/substance-abuse-horizon-scan-high-impact-1406.pdf
    January 01, 2020 - opioid abuse treatment. … overdoses: opioid misuse and dependence. … Prescription opioid abuse in chronic pain: a review of opioid abuse predictors and strategies to … curb opioid abuse. … Responding to opioid overdose. [internet].

38. Systematic Review on Treatments for Acute Pain: Surveillance Report 2 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/main-apps-surv-report-2-acute-pain.pdf
    May 01, 2022 - use of prescribing opioid therapy for acute pain conditions; and factors influencing opioid prescribing … (or/1-4) and (5 or 6) 8. exp Analgesics, Opioid/ 9. opioid*.ti,ab,kw. 10. … (or/1-4) and (5 or 6) 8. exp Analgesics, Opioid/ 9. opioid*.ti,ab,kw. 10. … for predicting risk of opioid misuse, opioid use disorder, or overdose? … for predicting risk of opioid misuse, opioid use disorder, or overdose?

39. Systematic Review on Treatments for Acute Pain: Surveillance Report 1 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/main-apps-surv-rept-1-acute-pain.pdf
    May 01, 2022 - evaluated an opioid alone. … (or/1-4) and (5 or 6) 8. exp Analgesics, Opioid/ 9. opioid*.ti,ab,kw. A-6 10. … (or/1-4) and (5 or 6) 8. exp Analgesics, Opioid/ 9. opioid*.ti,ab,kw. 10. … for predicting risk of opioid misuse, opioid use disorder, or overdose? … for predicting risk of opioid misuse, opioid use disorder, or overdose?

40. Treatments for Acute Pain: A Systematic Review (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/ehc-protocol-acute-pain-treatments.pdf
    August 08, 2019 - Opioid prescribing quadrupled from 1999 to 2010; concurrently, the number of opioid analgesics deaths … used; (4) the duration of opioid therapy; (5) opioid use history; or (6) substance use history? … for predicting risk of opioid misuse, opioid use disorder, or overdose? … for predicting risk of opioid misuse, opioid use disorder, or overdose? … (or/1-4) and (5 or 6) 8. exp Analgesics, Opioid/ 9. opioid*.ti,ab,kw. 10.