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181. March 3rd Impact of Healthcare Algorithms on Racial and Ethnic Disparities in Healthcare (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/impact-healthcare-algorithms-racial-ethnic-disparities-March-3.pdf
     July 01, 2023 - costs of utilization Intensive care needs Kidney function Lung function Lung cancer screening Opioid … algorithms for Black and White patients 2 COAG for warfarin dosing Novel risk prediction algorithm for opioid … the-problem-with-an- ai-based-overdose-risk-score-for-pain-medications/ See also: https://www.wired.com/story/opioid-drug-addiction … /the-problem-with-an-ai-based-overdose-risk-score-for-pain-medications/ https://www.wired.com/story/opioid-drug-addiction-algorithm-chronic-pain

182. Pharmacotherapy for Adults With Alcohol Use Disorder in Outpatient Settings (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/alcohol-misuse-drug-therapy_policymaker.pdf
     August 01, 2016 - Extended-release naltrexone for alcohol and opioid dependence: a meta-analysis of healthcare utilization

183. Methods White Paper: Improving the Utility of Evidence Synthesis for Decision Makers in the Face of Insufficient Evidence (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/improving-utility-evidence-synthesis-white-paper.pdf
     April 01, 2021 - Guidelines for Quality Palliative Care" NR Effects of medication assisted treatment (MAT) for opioid … Is buprenorphine more effective than clonidine to reduce opioid use or achieve abstinence. … Effect and harms of opioid switching/rotation 3. Comparison of opioid formulations 4. … review discussed in peer review feedback Medication -Assisted Treatment Models of Care for Opioid … Medication-assisted treatment models of care for opioid use disorder in primary care settings.

184. Rapid Evidence Product: Misuse of ADHD Prescription Stimulants in Adults (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/misuse-adhd-prescription-rapid-research.pdf
     July 01, 2025 - inhalant use disorder (11.4%), prescription tranquilizer/sedative disorders (9.8%), and prescription opioid … Associations between prescription and illicit stimulant and opioid use in the United States, 2015–2020 … Psychosocial functioning associated with prescription stimulant and opioid misuse versus illicit drug … prior to using illicit substances, prescription stimulant non-medical use preceded prescription opioid … of administration: NR Health: Rate of fatal overdose in Kentucky, Stimulant medication without opioid

185. Evidence Summary_Comparative Effectiveness Review No. 247_Interventional Treatments for Acute and Chronic Pain: Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-247-interventional-treatments-acute-chronic-pain-evidence-summary_0.pdf
     September 01, 2021 - quality of life, health status (e.g., Short-Form 36 Health Survey [SF-36]), mood, analgesic (including opioid

186. Pharmacotherapy for Adults with Alcohol-Use Disorders in Outpatient Settings (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/alcohol-misuse-drug-therapy-surveillance.pdf
     September 01, 2017 - 6: Are any of the medications more or less effective for adults with specific genotypes (e.g., mu-opioid … more or less effective for adults with specific genotypes (e.g., related to polymorphisms of the mu-opioid … Use of disulfiram for alcohol relapse prevention in patients in opioid maintenance treatment. … Feasibility and safety of extended-release naltrexone treatment of opioid and alcohol use disorder in … An evaluation of mu-opioid receptor (OPRM1) as a predictor of naltrexone response in the treatment of

187. Evaluation of Mental Health Applications (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/mental-health-app-protocol-updated.pdf
     January 01, 2018 - depression, anxiety, substance use disorders, post- traumatic stress disorder, bipolar disorder, psychosis, opioid … Post Traumatic Stress disorder”, “PTSD”, “psychotherapy”, “substance abuse disorders”, “psychosis”, “opioid

188. Research White Paper - Assessing the Predictive Validity of Strength of Evidence Grades: A Meta-Epidemiological Study (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/grades-predictive-values_white-paper.pdf
     September 01, 2015 - with agonist maintenance treatments versus agonist maintenance treatments alone for treatment of opioid … Methadone at tapered doses for the management of opioid withdrawal. … Buprenorphine for the management of opioid withdrawal.

189. Living Systematic Review on Cannabis and Other Plant-Based Treatments for Chronic Pain | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/plant-based-chronic-pain-treatment/living-review

190. Comparative Effectiveness of Analgesics To Reduce Acute Pain in the Prehospital Setting | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/acute-pain-ems/research

191. Restless-Legs Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/restless-legs_executive.pdf
     November 01, 2012 - 1 Comparative Effectiveness Review Number 86 Treatment for Restless Legs Syndrome Executive Summary Introduction Restless legs syndrome (RLS) is a neurological disorder characterized by unpleasant sensations in the legs and a distressing, irresistible urge to move them. RLS can result in reduced quality o…

192. Treatment of Acute Pain: An Evidence Map | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/acute-pain-treatment/protocol

193. Topic Brief: Updating Pharmacotherapy for Adults with Alcohol Use Disorders in Outpatient Settings (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/nt_docs/topic-brief-updating-pharmacotherapy.pdf
     September 30, 2022 - adults with AUD more or less effective for adults with certain genetic polymorphisms (e.g., of the mu-opioid … review examined whether the presence of the A118G genotype of the OPRM1 gene (the gene encoding for opioid … Systematic review and meta-analysis of the moderating effect of rs1799971 in OPRM1, the mu-opioid receptor … An analysis of the effect of mu-opioid receptor gene (OPRM1) promoter region DNA methylation on the

194. Disposition of Comments for CER 183 Tonsillectomy for OSDB (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/tonsillectomy-disposition-170415.pdf
     January 17, 2017 - Many studies address perioperative use of opioids; however, our KQ did not address perioperative opioid

195. Maternal Morbidity and Mortality (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/mmm-draft-protocol-amendment.pdf
     February 02, 2022 - Amphetamine- and Opioid-Affected Births: Incidence, Outcomes, and Costs, United States, 2004-2015. … Medications for opioid use disorder among pregnant women referred by criminal justice agencies before

196. final Fibromyalgia CER protocol_3-31-14 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/fibromyalgia_research-protocol.pdf
     April 03, 2014 - serotonin-reuptake inhibitors such as fluoxetine) o Antiepileptics (such as pregabalin or gabapentin) o Non-opioid … analgesics o Nonsteroidal anti-inflammatory drugs (NSAIDs) o Opioid analgesics o Skeletal muscle … Opioid use, misuse, and abuse in patients labeled as fibromyalgia.

197. McCormack-notes-151008 copy - Teresa (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/mccormack-presentation.pdf
     May 29, 2025 - spotlight; for example, it is part of the national pain  strategy because we are dealing with  an  opioid

198. Treatment for Restless Legs Syndrome Disposition of Comments Report (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/restless-legs_disposition-comments.pdf
     November 27, 2012 - This should read “no eligible RCT studies evaluated these agents” as there are a number of long-term opioid

199. Supplemental Project To Assess the Transparency of Reporting Requirements for Studies Evaluating the Effectiveness of Treatment Options for Symptoms of Diabetic Peripheral Neuropathy (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/transparency-neuropathy_research.pdf
     March 01, 2018 - Detailed Results We identified five studies (all with available data) that compared an atypical opioid

200. Amended Protocol: Improving Rural Health Through Telehealth-Guided Provider-to-Provider Communication (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/rural-telehealth-amended-protocol.pdf
     February 25, 2021 - studied1 and include higher mortality2-5 and morbidity from a wide range of conditions such as substance/opioid … Understanding the rural-urban differences in nonmedical prescription opioid use and abuse in the United … Examining rural/urban differences in prescription opioid misuse among US adolescents.