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101. Noninvasive, Nonpharmacological Treatment for Chronic Pain (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/nonpharma-treatment-pain_research-protocol-amended.pdf
     September 20, 2017 - At the same time, the NPS points to the “dual crises” of chronic pain and opioid dependence, overdose … The 2016 CDC Guidelines for Prescribing Opioids for Chronic Pain recommend that non-opioid therapy … Trends in long-term opioid therapy for chronic non-cancer pain. … Opioid prescriptions by U.S. primary care physicians from 1992 to 2001. … Vital signs: overdoses of prescription opioid pain relievers---United States, 1999--2008.

102. Comparative Effectiveness of Pain Management Interventions fo Hip Fracture (ppt file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/hip-fracture-pain.ppt
     May 01, 2011 - Systemic opioid analgesics present complications that include alterations in mental status, nausea and … Comparators: usual care (non-narcotic and opioid), and/or other interventions. … Comparators: usual care (non-narcotic and opioid systemic analgesia) and/or other interventions. … , benefits, and harms of the systemic analgesics commonly used in pain management (non-narcotic and opioid … VAS, cm* (95% CI) Strength of Evidence Acupressure (preoperative) Sham control and standard care (opioid

103. Comparative Effectiveness of Pain Management Interventions fo Hip Fracture (ppt file)
     effectivehealthcare.ahrq.gov/sites/default/files/hip-fracture-pain.ppt
     May 01, 2011 - Systemic opioid analgesics present complications that include alterations in mental status, nausea and … Comparators: usual care (non-narcotic and opioid), and/or other interventions. … Comparators: usual care (non-narcotic and opioid systemic analgesia) and/or other interventions. … , benefits, and harms of the systemic analgesics commonly used in pain management (non-narcotic and opioid … VAS, cm* (95% CI) Strength of Evidence Acupressure (preoperative) Sham control and standard care (opioid

104. Intergrated and Comprehensive Pain Management Programs: Effectiveness and Harms: Evidence Summary (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/cer-251-integrated-pain-management-evidence-summary.pdf
     October 01, 2021 - and assessed strength of evidence (SOE) for the primary outcomes of function, pain, and changes in opioid … with a least low strength of evidence for IPMPs for noncancer pain: Key Question 1 (pain, function, opioid … months) None + No evidence No evidence Long term (≥12 months) None + None + None + Opioid … factors were not generally reported in studies; we could not evaluate their impact on function, pain, or opioid

105. Executive Summary - Living Systematic Review on Cannabis and Other Plant-Based Treatments for Chronic Pain: 2023 Update (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-executive-summary-2023-update.pdf
     January 01, 2023 - event outcomes (psychosis, cannabis use disorder, cognitive deficits) and outcomes on the impact on opioid … 12 to 208 52 26 24 24 8 Abbreviations: CBD = cannabidiol; LAO = long-acting opioid … reporting of important outcomes such as dosage, pain response, overall function or disability, effect on opioid … Effectiveness, Safety, and Tolerability of Nabiximols Oromucosal Spray vs Typical Oral Long-Acting Opioid … J Opioid Manag. 2009 Nov-Dec;5(6):341-57. doi: 10.5055/jom.2009.0034. PMID: 20073408. 6.

106. Noninvasive Treatments for Low Back Pain: A Summary of the Research for Adults (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/back-pain-treatment_consumer.pdf
     November 01, 2016 - ��Taking opioids while pregnant may cause the unborn baby to have a condition called neonatal opioid

107. Living Systematic Review on Cannabis and Other Plant-Based Treatments for Chronic Pain: Surveillance Report 3 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-surveillance-report-3_0.pdf
     May 01, 2022 - Opioid treatments for chronic pain. … Opioid Treatments for Chronic Pain. Comparative Effectiveness Review No. 229. … b Only included outcome reported was opioid-use. … Does integrative medicine reduce prescribed opioid use for chronic pain? … The impact of cannabis access laws on opioid prescribing.

108. Systematic Review on Acute Treatments for Episodic Migraine: Surveillance Report 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/episodic-migraine-surveillance-report-1.pdf
     June 01, 2022 - Opioid Pharmacologic Therapy No new studies addressed the comparative effectiveness or harms of opioid … What are the effects of prescribing opioid therapy versus not prescribing opioid therapy for acute treatment … the accuracy of instruments for predicting risk of opioid misuse, opioid use disorder, or overdose? … the effectiveness of instruments for predicting risk of opioid misuse, opioid use disorder, or overdose … Opioid Therapy: KQ1 a-e.

109. Living Systematic Review on Cannabis and Other Plant-Based Treatments for Chronic Pain: Surveillance Report 2 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-apps-a-e-surveillance-report-2-final_0_0.pdf
     March 01, 2022 - Opioid Treatments for Chronic Pain. Comparative Effectiveness Review No. 229. … J Opioid Manag. 2009 Nov-Dec;5(6):341-57. PMID: 20073408. 13. … Opioid Treatments for Chronic Pain. Comparative Effectiveness Review No. 229. … b Only included outcome reported was opioid-use. … Does Integrative Medicine Reduce Prescribed Opioid Use for Chronic Pain?

110. AHRQ's Evidence-based Practice Center Division Annual Report 2022: Solving the Puzzle for Evidence-Based Decision Making (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/pdf/epc-year-in-review-2022.pdf
     January 01, 2022 - .............................................. 4 Impact Snapshot 1: AHRQ Reports inform CDC’s 2022 Opioid … harms, opioid medications are often prescribed for many pain conditions. … This has resulted in greater incidence of opioid use disorder and opioid-related overdose death. … The CDC guidance continues to recommend non-opioid options as first line of treatment for pain. … Opioid Treatments for Chronic Pain 15.

111. AHRQ Slide Template
     effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/pdf/epc-pain-management-grand-rounds-slides.pptx
     March 01, 2022 - Examine the role of opioids in pain management and the opioid crisis. 4. … disorder, serious adverse events) Secondary: Psychological (depression and anxiety), quality of life, opioid … , sedation, nausea); studies not designed to assess serious risks, long-term outcomes, or impact on opioid … systematic reviews as outlined by AHRQ Patient: Adults with episodic migraine Intervention: Systemic opioid … nonopioid abortive drug, or noninvasive nonpharmacologic abortive therapy Comparison: Placebo, another opioid

112. Tratamientos no invasivos para el dolor lumbar: Resumen de la investigación para adultos (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/back-pain-treatment_consumer-Spanish.pdf
     July 01, 2017 - Tratamientos no invasivos para el dolor lumbar: Resumen de la investigación para adultos e Tratamientos no invasivos para el dolor lumbar Resumen de la investigación para adultos ¿Es esta información apropiada para mí? Esta información es apropiada para usted si: � Tiene dolor lumbar; es decir, dolor en la pa…

113. Making Healthcare Safer IV: Summary of Findings, 2023-2024 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs-IV-1-year-final-report-updated-title_0.pdf
     May 01, 2024 - Opioid Stewardship .................................................................................. … Opioid Stewardship 4a. … o The TEP also recommended exploring unintended consequences of opioid stewardship interventions and … Opioid Stewardship • The TEP encouraged adoption of three types of PSPs for opioid stewardship: o … Opioid Stewardship 4a. Findings From Previous MHS Reports 4b. MHS IV Rapid Review Findings 4c.

114. Systematic Review Update: Noninvasive Nonpharmacologic Treatment for Chronic Pain (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/nonpharm-treatment-chronic-pain-protocol.pdf
     December 11, 2018 - The recent publication of evidence-based guidelines on opioid use for chronic pain by the Centers for … Given this need and wide- spread concern regarding opioid use and misuse outlined in recent guidelines … Trends in long-term opioid therapy for chronic non-cancer pain. … Opioid prescriptions by U.S. primary care physicians from 1992 to 2001. … Vital signs: overdoses of prescription opioid pain relievers---United States, 1999--2008.

115. Effective Health Care (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0108_05-24-2009.pdf
     January 01, 2009 - Effective Health Care Topic Number(s): 0156 Document Completion Date: 1-12-10 1 Results of Topic Selection Process & Next Steps  Acute migraine treatment in emergency settings will go forward for refinement as a systematic review. The scope of this topic, including populations, interventions, c…

116. Noninvasive Treatments for Low Back Pain: Current State of the Evidence (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/back-pain-treatment_clinician.pdf
     November 01, 2016 - Noninvasive Treatments for Low Back Pain: Current State of the Evidence Noninvasive Treatments for Low Back Pain: Current State of the Evidence Focus of This Summary This review examines the evidence on the comparative benefits and harms of noninvasive treatments for acute, subacute, and chronic low back pain fro…

117. Acute Treatments for Episodic Migraine: Surveillance Report 3 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/episodic-migraine-surveillance-report-3.pdf
     August 01, 2022 - Opioid Pharmacologic Therapy No new studies addressed the comparative effectiveness or harms of opioid … Opioid Therapy a. … the accuracy of instruments for predicting risk of opioid misuse, opioid use disorder, or overdose? … the effectiveness of instruments for predicting risk of opioid misuse, opioid use disorder, or overdose … Opioid Therapy: KQ1 a-e.

118. Disposition of Comments Report for Acute Migraine Treatment in Emergency Settings (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/migraine-emergency_disposition-comments.pdf
     November 27, 2012 - Similarly it would be very hard (if not impossible) to prove that a single dose of an opioid for a … We do not make the claim that a single dose of an opioid leads to physical dependence. … Peer Reviewer #1 Results In the opioids section greater detail about opioid dosing would improve … therefore be clear in tables such as Table 15, and discussion about therapeutic vs. subtherapeutic opioid

119. Management of Suspected Opioid Overdose with Naloxone by Emergency Medical Services Personnel | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/emt-naloxon/systematic-review

120. Cancer Quality-ASSIST Supportive Oncology Quality Indicator Set: Feasibility, Reliability, and Validity Testing (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/cancer-quality-indicator-testing_research.pdf
     April 01, 2010 - For example, the ASSIST quality indicator “IF a cancer patient is receiving a long-acting opioid for … cancer pain, THEN he or she should also be prescribed a short- acting opioid for breakthrough pain,” … is expressed as The number of patients receiving a short and long-acting opioid The number of … cancer patients receiving a long-acting opioid 2 Effective Health Care Program Research Report … formulation, then a short-acting opioid formulation for breakthrough pain should also be provided