-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/medical-test-reviews-meta-analysis.ppt
June 01, 2012 - times after symptom onset. … The sensitivity of the test increased as the time from symptom onset increased. … The sensitivity increased when the levels of CK-MB were tested further out from symptom onset. … The red area shows the confidence regions when the CK-MB was tested >3 hours from symptom onset. … versus more than 3 hours from onset.
-
effectivehealthcare.ahrq.gov/sites/default/files/medical-test-reviews-meta-analysis.ppt
June 01, 2012 - times after symptom onset. … The sensitivity of the test increased as the time from symptom onset increased. … The sensitivity increased when the levels of CK-MB were tested further out from symptom onset. … The red area shows the confidence regions when the CK-MB was tested >3 hours from symptom onset. … versus more than 3 hours from onset.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0107_05-19-2009.pdf
January 01, 2009 - allergen avoidance,
environmental controls, and/or pharmacotherapy
Outcome(s): Prevention of the onset
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/antidepressants-update_executive.pdf
December 01, 2011 - Specifically, consistent evidence from multiple trials
demonstrates that mirtazapine has a faster onset … For example, a faster onset of
mirtazapine must be weighed against possible
decreased adherence because … faster onset of action than citalopram, fluoxetine,
paroxetine, and sertraline. … Most other
trials do not indicate a faster onset of action of one second-generation
antidepressant … Comparative effectiveness Insufficient No evidence
Quality of life Insufficient No evidence
Onset of
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/acute-pain-ems-protocol-amendment.pdf
January 28, 2019 - KQ 3: In patients whose moderate-to-severe acute-onset pain level is not controlled
following initial … KQ 4: In patients whose moderate-to-severe acute-onset pain level is not controlled
following initial … following PICOTS criteria apply:
Population(s):
• KQ 1-4:
o Patients of any age with acute onset … o KQ2c: EMS personnel that administer or handle analgesics in the care of
patients with acute onset, … criteria for KQs
Category Inclusion Criteria Exclusion Criteria
Population KQ 1-4: Any age with acute onset
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-metaanalysis_methods.pdf
July 01, 2012 - department.17,18 Figure 8–5
shows the 14 eligible studies along with how many hours after symptom onset … versus greater than
3 hours from symptom onset (Table 8–2 and Figure 8–5). … we include a variable that
codes whether the last measurement was earlier than 3 hours from symptom onset … The numbers next to each study point are the actual length of the time interval from
symptom onset to … The meta-regression is on
a variable that takes the value 1 if the time from the onset of symptoms to
-
effectivehealthcare.ahrq.gov/sites/default/files/cer-236-mental-health-pregnancy-evidence-summary.pdf
April 01, 2021 - Specifically, for depression, three RCTs offered evidence that brexanolone for
depression onset in the … For depression onset in the third trimester or within 4 weeks
of birth, brexanolone may be associated
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0359_10-15-2010.pdf
January 01, 2010 - Population(s): Patients suspected of having multiple sclerosis due to neurologic deficits
of subacute onset
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/restless-legs_research-protocol.pdf
December 16, 2011 - together by patient
and investigator
to assess severity of
augmentation defined as: earlier
onset … screener for augmentation
*Augmentation is characterized by: greater intensity of symptoms; earlier onset … of symptoms; shorter latency
to onset of symptoms during inactivity; and spread of symptoms to other … Defining the phenotype of the restless legs syndrome (RLS) using age-of-
symptom-onset. … (e.g.,earlier onset of symptoms at night, shorter
latency to onset of symptoms, appearance of daytime
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/juvenile-arthritis-dmards_surveillance.pdf
March 14, 2013 - Anakinra: A safe and effective first-line
treatment in systemic onset juvenile
idiopathic arthritis … Subjects Primary Outcome Duration Findings
Quartier, 201121 RCT, anakinra vs placebo 24 Systemic- onset … JIA
patients from 2005-2010
4 Systemic- onset JIA with
first-line anakinra-
treatment
Efficacy … Partial
responders were younger at onset
(median 5.2 years vs 10.2 years;
P=0.004). … Median
time of onset was 6 years and 10
months.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/juvenile-arthritis-dmards_surveillance.pdf
March 14, 2013 - Anakinra: A safe and effective first-line
treatment in systemic onset juvenile
idiopathic arthritis … Subjects Primary Outcome Duration Findings
Quartier, 201121 RCT, anakinra vs placebo 24 Systemic- onset … JIA
patients from 2005-2010
4 Systemic- onset JIA with
first-line anakinra-
treatment
Efficacy … Partial
responders were younger at onset
(median 5.2 years vs 10.2 years;
P=0.004). … Median
time of onset was 6 years and 10
months.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0210_12-07-2009.pdf
January 01, 2009 - The sudden onset of TBI combines with extreme changes in behavior, personality, memory,
and general
-
effectivehealthcare.ahrq.gov/sites/default/files/s166.pdf
October 01, 2007 - trials (RCTs) that compared
these treatments with placebo, we assessed the following
outcomes: sleep onset … latency (SOL), wakefulness after
sleep onset (WASO), sleep efficiency (SE), total sleep time
(TST), … Sleep Onset Latency
Results were clinically and statistically similar across
comparisons. … There was less than 1 minute difference in sleep
onset across the 6 comparisons, and an insignificant … Wakefulness After Sleep Onset
WASO values among the 6 comparisons ranged from a
10-minute advantage
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/labor-dystocia_research-protocol.pdf
July 28, 2016 - issues
Women 15-44
with
uncomplicated
pregnancies at
37-42 weeks
gestation with
spontaneous
onset … hypocontractile labor"[tiab]
#2 "Labor, Obstetric"[Mesh] OR "Delivery, Obstetric"[Mesh] OR "Labor Onset … labour"[tiab] OR "normal labor"[tiab] OR "normal labour"
OR "term labor" OR "term labour" OR "labor onset … tiab] OR "Cervical
Dilatation"[tiab] OR "Cervical Dilatations"[tiab]))
#3 #1 AND #2
#4 ("Labor Onset … "[Mesh] OR "labor onset"[tiab] OR “labour onset”[tiab] OR "Second
Labor Stages"[tiab] OR “Second Labour
-
effectivehealthcare.ahrq.gov/sites/default/files/08_functional_limitations_potential_high_impact_2012-12-10.pdf
January 01, 2012 - ........................................... 5
Ezogabine (Potiga) for Treatment-Resistant, Partial-Onset … Overall high-impact potential: ezogabine (Potiga) for treatment-resistant, partial-
onset epilepsy . … Epilepsy
Partial-onset seizures are the most common form of epileptic seizures. … In all
studies of patients with partial-onset seizures, including open-label studies, five patients … Ezogabine: a novel antiepileptic as
adjunctive therapy for partial onset seizures.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ischemic-stroke-treatment_executive.pdf
January 01, 2011 - patient baseline characteristics, disease
severity, location of occluded artery, time from
symptom onset … 18 years
of age, with baseline NIHSS scores ≥8 (or ≥10),
presenting within 8 hours of stroke symptom onset … contraindications to receive IV rtPA due to risks of
adverse events, reporting outside a 3-hour window from
symptom onset … Embolectomy (MR RESCUE) trial, which
will allow patients to receive IV rtPA up to 4.5 hours
after symptom onset
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/depression-brain-injury_research-protocol.pdf
December 09, 2009 - Whether the etiology of the depression is neurobiological or situational may also affect the
time of onset … ; earlier onset depression may be more likely to have a neuroanatomic source, while
later onset may
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/epilepsy-medicine_research-protocol.pdf
February 01, 2008 - Unclassified Seizures Neonatal seizures
Infantile spasms
Age and Epilepsy
The incidence of new-onset … during the first nine years of life and then
plateaus over the next 30 years.1 The incidence of new onset … epilepsy drops in 40-59 year olds,
and then rises again in the elderly.4,5 The age of epilepsy onset … subgroup analyses for the older versus newer evaluation, we will evaluate the results in
those with new onset … Efficacy and
tolerability of the new antiepileptic drugs I: Treatment
of new onset epilepsy: Report
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0655-131114.pdf
May 22, 2013 - Socioeconomic strata
o Youth with co-morbidities (e.g., ADD/ADHD, anxiety, depression)
o Age of disorder onset
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/depression-brain-injury_executive.pdf
April 01, 2011 - In aggregate for all those
with TBI, onset of major depression within 3 months of
injury has been reported … In contrast, delayed-onset major depression
was not associated with lesion location. … understand the relationship
between pathophysiology related to the brain injury and
risk and timing of onset … depression
(74 percent of late-onset patients) and lowest among
those in the chronic depression group … Comparison between
acute- and delayed-onset depression following traumatic brain
injury.