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  1. Diabetes Mellitus (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/diabetes-horizon-scan-high-impact-1406.pdf
    September 26, 2014 - T2DM and mild obesity, as follows.99 For up to 6 years following RYGB, durable diabetes remission occurred … In patients who were phakic in the study eye at baseline, cataracts occurred in 82 % of fluocinolone … An improvement ≥2 steps in the [ETDRS] retinopathy scale occurred in 13.7% (low dose) and 10.1% ( … Benefit occurred for both doses compared with sham at 3 weeks and all subsequent time points. … Glaucoma requiring incisional surgery occurred in 3.7%, 7.6%, and 0.5% of the low-dose, high- dose
  2. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cell-free-dna-executive-summary.pdf
    May 01, 2025 - exposure 1 single-arm cohort study (9,911) Unnecessary radiation exposure of approximately 25 mSV occurred
  3. effectivehealthcare.ahrq.gov/sites/default/files/medical-test-reviews-options-summarizing.ppt
    June 01, 2012 - If misclassification occurred, it would be more likely an underestimation of diagnostic accuracy.
  4. effectivehealthcare.ahrq.gov/sites/default/files/related_files/medical-test-reviews-options-summarizing.ppt
    June 01, 2012 - If misclassification occurred, it would be more likely an underestimation of diagnostic accuracy.
  5. effectivehealthcare.ahrq.gov/sites/default/files/arthritis-horizon-scan-high-impact-1512.pdf
    December 29, 2015 - were headache, nasopharyngitis, and upper respiratory tract infection; no opportunistic infections occurred … No opportunistic infections or cases of tuberculosis (TB) occurred. … No opportunistic infections occurred; one case of TB and one case of NMSC occurred in the baricitinib … One case of TB occurred in the adalimumab group.65 15 In the RA-BEGIN trial comparing baricitinib … Two cases of malignancy occurred in the baricitinib/methotrexate group.66 Manufacturer and regulatory
  6. effectivehealthcare.ahrq.gov/sites/default/files/pdf/vitamin-d-calcium_research-protocol.pdf
    September 13, 2013 - studies of interventions; prospective, longitudinal observational studies (where the measure of exposure occurred … cross-sectional studies and traditional, retrospective case-control studies (where the measure of exposure occurred
  7. effectivehealthcare.ahrq.gov/sites/default/files/pdf/back-pain-treatment_clinician.pdf
    November 01, 2016 - Studies have shown that improvements in pain (mean reduction to 58% of initial pain scores) occurred
  8. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0371_11-23-2010.pdf
    January 01, 2010 - Effective Health Care Topic Number: 0313 Document Completion Date: 12-12-11 1 Results of Topic Selection Process & Next Steps  Outcomes of serious mental illness will go forward for refinement as a systematic review. The scope of this topic, including populations, interventions, comparators, and…
  9. effectivehealthcare.ahrq.gov/sites/default/files/related_files/blood-clots-hip-knee-surgery_disposition-comments.pdf
    March 01, 2012 - The interventions being compared are listed in all cases, even when no events occurred in any of the … In RECORD1 the primary efficacy endpoint occurred in 1.1% of patients receiving rivaroxaban compared … In RECORD2, the primary efficacy endpoint occurred in 2% of patients receiving the extended regimen … Major bleeding occurred in 0.1% of patients in both treatment groups. … In RECORD3, the primary efficacy endpoint occurred in 9.6% of patients receiving rivaroxaban 10 mg once
  10. Diabetes Mellitus (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/diabetes-horizon-scan-high-impact-1512.pdf
    December 01, 2015 - manufacturers suggest that Afrezza therapy was associated with reduced pulmonary function that occurred … No deaths occurred. … Severe hypoglycemic events occurred in 5.1% of the Afrezza group (n=177) and 1.7% of the placebo group … Afrezza therapy was associated with reduced pulmonary function that occurred during the first 3 months … A 15% or larger decline in FEV1 occurred in 6% of Afrezza-treated subjects compared with 3% of subjects
  11. effectivehealthcare.ahrq.gov/sites/default/files/module-iii-points-of-engagement-in-the-ehc-program.pdf
    May 29, 2025 - Module III: Points of Engagement in the EHC Program …
  12. Menopause Executive (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/menopause_executive.pdf
    March 01, 2015 - on menopausal women, it was difficult to discern if exposure (e.g., to SSRIs/SNRIs or isoflavones) occurred
  13. effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-grading-strength_methods.pdf
    July 01, 2009 - association refers to the likelihood that the observed effect is large enough that it cannot have occurred … Use one of two levels: • Strong: Large effect size that is unlikely to have occurred in the absence … of a true effect of the intervention • Weak: Small enough effect size that it could have occurred
  14. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/type-2-diabetes-medications-2007_executive.pdf
    January 01, 2007 - the withdrawal from a prior sulfonylurea (and withdrawal of its weight- increasing effect) that often occurred … had a similar risk of minor hypoglycemia compared with metformin monotherapy, and no serious events occurred … No serious events occurred in either group in these RCTs. 4&5b.
  15. effectivehealthcare.ahrq.gov/sites/default/files/related_files/grading.ppt
    January 01, 2010 - Magnitude of effect: Defined as the likelihood that the observed effect is large enough that it cannot have occurred … scores are possible for strength of association: Strong: large effect size that is unlikely to have occurred … Weak: small enough effect size that it could have occurred solely as a result of bias from confounding
  16. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0655-131114.pdf
    May 22, 2013 - Topic 0559 Disruptive Behavior Disorders in Children NSD FINAL SJ Comparative Effectiveness of Treatments for Disruptive Behavior Disorders in Children Nomination Summary Document …
  17. effectivehealthcare.ahrq.gov/sites/default/files/c-diff-infections-nomination-140925.pdf
    February 19, 2014 - Update Topic CER 31 Clostridium difficile NSD FINAL Effectiveness of Early Diagnosis, Prevention, and Treatment of Clostridium difficile Infection Nomination …
  18. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0262_05-11-2007.pdf
    January 01, 2007 - Effective Health Care Topic Number(s): 0111 Document Completion Date: 5-19-09 1 Results of Topic Selection Process & Next Steps  Urinary incontinence will go forward for refinement as an update to or expansion of an existing comparative effectiveness or effectiveness review. The scope of thi…
  19. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0193_08-12-2009.pdf
    January 01, 2009 - Effective Health Care Topic Number(s): 0184-0193 Document Completion Date: 2-23-10 1 Results of Topic Selection Process & Next Steps  Interventions to improve prescription medication adherence will be considered for refinement as an umbrella review of systematic reviews to outline current evi…
  20. effectivehealthcare.ahrq.gov/sites/default/files/pdf/assessing-the-risk-of-bias-in-systematic-reviews-of-health-care-interventions-01_0.pdf
    May 01, 2005 - Study investigators may assume that patients will know when an adverse event has occurred, accurately

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