-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/main-apps-surv-rept-1-acute-pain.pdf
May 01, 2022 - Systematic Review on Treatments for Acute Pain: Surveillance Report 1
Systematic Review on Treatments … We separately evaluated single dose trials and multidose trials (i.e.,
trials that evaluated a course … 1 RCT)
One new RCT (n=412) found
similar effects of a multidose
course of an opioid alone vs. … Treatments for Acute Pain: A Systematic
Review. Comparative Effectiveness Review
No 240. … CADTH Health
Technology Review.
-
effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/main-apps-surv-rept-1-acute-pain.pdf
February 01, 2022 - Systematic Review on Treatments for Acute Pain: Surveillance Report 1
1
Systematic Review on Treatments … We separately evaluated single dose trials and multidose trials (i.e.,
trials that evaluated a course … 1 RCT)
One new RCT (n=412) found
similar effects of a multidose
course of an opioid alone vs. … Treatments for Acute Pain: A Systematic
Review. Comparative Effectiveness Review
No 240. … CADTH Health
Technology Review.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/surveillance-report-1-treatments-for-acute-pain.pdf
January 01, 2022 - We separately evaluated single dose trials and multidose trials (i.e.,
trials that evaluated a course … KQ6: Dental pain
• One new trial found similar effects of a multidose course of an opioid plus NSAID … acetaminophen,
multidose
Evidence limited and
inconsistent for pain and
other outcomes; each RCT … NSAID,
multidose
Pain, <1 day and 1 day to
<1 week: no difference
(SOE: insufficient, based on … CADTH Health
Technology Review.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/main-apps-surv-report-2-acute-pain.pdf
May 01, 2022 - We separately evaluated single dose trials and multidose trials (i.e.,
trials that evaluated a course … KQ6: Dental Pain
• One new trial found a multidose course of an opioid plus acetaminophen or NSAID … acetaminophen,
multidose
Evidence limited and
inconsistent for pain and
other outcomes; each RCT … NSAID,
multidose
Pain, <1 day and 1 day to
<1 week: No difference
(SOE: low, based on 1 RCT
[<1 … 1 RCT)
One RCT (n=412) found similar
effects of a multidose course of
an opioid alone vs.
-
effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/main-apps-surv-report-2-acute-pain.pdf
May 01, 2022 - We separately evaluated single dose trials and multidose trials (i.e.,
trials that evaluated a course … KQ6: Dental Pain
• One new trial found a multidose course of an opioid plus acetaminophen or NSAID … acetaminophen,
multidose
Evidence limited and
inconsistent for pain and
other outcomes; each RCT … NSAID,
multidose
Pain, <1 day and 1 day to
<1 week: No difference
(SOE: low, based on 1 RCT
[<1 … 1 RCT)
One RCT (n=412) found similar
effects of a multidose course of
an opioid alone vs.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/main-apps-surv-report-3-acute-pain.pdf
June 01, 2022 - We separately evaluated single dose trials and multidose trials (i.e.,
trials that evaluated a course … acetaminophen,
multidose
Evidence limited and
inconsistent for pain and
other outcomes; each RCT … NSAID,
multidose
Pain, <1 day and 1 day to
<1 week: No difference
(SOE: low, based on 1 RCT
[<1 … NSAID,
multidose
Pain, <1 day and 1 day to
<1 week: No difference
(SOE: insufficient, based on … acetaminophen,
multidose course
Pain, <1 day: One very
small (n=20) RCT found
opioid associated
-
effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/main-apps-surv-report-3-acute-pain.pdf
May 06, 2022 - We separately evaluated single dose trials and multidose trials (i.e.,
trials that evaluated a course … acetaminophen,
multidose
Evidence limited and
inconsistent for pain and
other outcomes; each RCT … NSAID,
multidose
Pain, <1 day and 1 day to
<1 week: No difference
(SOE: low, based on 1 RCT
[<1 … NSAID,
multidose
Pain, <1 day and 1 day to
<1 week: No difference
(SOE: insufficient, based on … acetaminophen,
multidose course
Pain, <1 day: One very
small (n=20) RCT found
opioid associated
-
effectivehealthcare.ahrq.gov/sites/default/files/cer-240-acute-pain-evidence-summary.pdf
December 01, 2020 - Evidence Summary for Treatments for Acute Pain: A Systematic Review
Comparative Effectiveness Review … Number 240
Treatments for Acute Pain: A
Systematic Review
Evidence Summary
Main Points … Background and Purpose
The purpose of this review is to evaluate the effectiveness and comparative … A multidose course of opioids
was probably associated with increased likelihood of repeat or rescue … Treatments for Acute Pain: A Systematic Review. Comparative Effectiveness Review
No. 240.
-
effectivehealthcare.ahrq.gov/sites/default/files/cer-240-acute-pain-revised-comments.pdf
December 29, 2020 - Review
Comparative Effectiveness Review Disposition of Comments Report
Research Review Title: Treatments … Treatments for Acute Pain: A Systematic Review. Comparative Effectiveness Review No.
240. … therapy evaluated a single treatment
session, potentially limiting the applicability
of findings to a multidose … The cited article is not a
Cochrane review, it is a review of
a Cochrane review that noted
that most … are
detailed in the Results and
Discussion section and findings
are separated out from trials of
multidose
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/hypertension-pulmonary-arterial_disposition-comments.pdf
April 25, 2013 - Comparative Effectiveness Review No. 117. … for this draft review. … Multidose studies
included only a single control group; we therefore did not
report each dose individually … We did not combine single
doses (e.g., 5 mg) because different multidose studies
had different control … Public Reviewer -
ACCP 3
General The review is excellent.