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461. Statin Use for the Primary Prevention of Cardiovascular Disease in Adults: Updated Evidence Report and Systematic Review fo the USPSTF (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/k_QR3hvh2jVSPPLu6Q6m6r
     November 13, 2022 - Statins were significantly associated with decreased risk of all-cause mortality (risk ratio [RR], 0.92 … The recommendations were based on evidence that statins are associated with reduced risk of mortality … mortality in asymptomatic adults without prior CVD events? … Meta-analysis: Statins vs Placebo or No Statin and All-Cause Mortality, Cardiovascular Mortality, and … mortality)18 and PROSPER (RR, 1.07 [95% CI, 0.86 to 1.35] for all-cause mortality; cardiovascular mortality

462. Final Research Plan: Unhealthy Alcohol Use in Adolescents and Adults: Screening and Behavioral Counseling Interventions | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/unhealthy-alcohol-use-in-adolescents-and-adults-screening-and-behavioral-counseling-interventions
     October 20, 2016 - for unhealthy alcohol use in adolescents and adults, including pregnant women, reduce morbidity or mortality … counseling interventions to reduce unhealthy alcohol use, with or without referral, reduce morbidity or mortality … Other risky behaviors (e.g., other drug use, risky sexual behaviors) KQs 1b, 4b: All-cause mortality … Alcohol-related mortality (intentional and unintentional) Alcohol-related morbidity (e.g., mental … emergency department and inpatient stays) Obstetrical/perinatal/neonatal outcomes (e.g., perinatal mortality

463. Screening for Dyslipidemia in Younger Adults: A Systematic Review (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/SaASReVeD_fpHZQbeBZD5s
     October 01, 2016 - , or on all-cause mortality? … , or on all-cause mortality? … , or on all-cause mortality? … , cardiovascular outcomes (CHD- or CVA-related mor- bidity or mortality), or harms of screening or treatment … ; all- cause mortality Harms of screening 6 Harms of treatment Numbers in circles correspond to the

464. Archived: Chronic Obstructive Pulmonary Disease: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/recommendation/chronic-obstructive-pulmonary-disease-screening-2016
     April 05, 2016 - studies that directly assessed the effects of screening for COPD in asymptomatic adults on morbidity, mortality … Two studies of LABAs found no difference in all-cause mortality but found decreased exacerbation of COPD … inhaled corticosteroids found decreased exacerbation of COPD symptoms but no difference in all-cause mortality … with corticosteroids and LABAs found decreased exacerbation of COPD symptoms but no differences in mortality … Mortality in the United States, 2013. NCHS Data Brief . 2014;(178):1-8. 2.

465. Screening for Peripheral Artery Disease Using the Ankle-Brachial Index: Updated Evidence Report and Systematic Review for the USPSTF (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/fXJESRpEwCmPh-FQobvtAY
     July 10, 2018 - MAIN OUTCOMES AND MEASURES Cardiovascular morbidity; PAD morbidity; mortality; health-related quality … Composite and Mortality Outcomes for Aspirin in Participants With Low Ankle-Brachial Index (Key Question … , cardiovascular morbidity and mortality, or both at 10 to 15 years of follow-up. … The authors hypothesized that the all-cause mortality benefit was largely seen from preventive measures … Ankle brachial index combined with Framingham Risk Score to predict cardiovascular events and mortality

466. Archived: Statin Use for the Primary Prevention of Cardiovascular Disease in Adults: Preventive Medication | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/recommendation/statin-use-in-adults-preventive-medication-november-2016
     November 13, 2016 - disease or ischemic stroke) use a low- to moderate-dose statin for the prevention of CVD events and mortality … Cardiovascular disease is the leading cause of morbidity and mortality in the United States, accounting … Use of low- or moderate-dose statins was associated with a reduced risk of all-cause mortality (pooled … or all-cause mortality in asymptomatic adults without a history of CVD events; whether the benefits … Total cholesterol and risk of mortality in the oldest old. Lancet . 1997;350(9085):1119-23.

467. Overdiagnosis in Prostate Cancer Screening Decision Models: A Contextual Review for the USPSTF (pdf file)
     www.uspreventiveservicestaskforce.org/Home/GetFile/1/16812/prostate-models-overdiagnosis/pdf
     May 01, 2018 - Uncertainties regarding the benefit of PSA screening in reducing prostate cancer mortality in randomized … of treatment—differs between populations, evidenced by differences in prostate cancer incidence and mortality … McGregor and colleagues19 used a cohort model with data on prostate cancer incidence and mortality in … from Human Mortality Database, years NR Proportion (1) of screen- detected cancers, or (2) of all … MISCAN-PRO* US population, mortality from standard US life tables, years NR Proportion (3) of

468. Chemo and Couns/2nd instal (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/-hnLT26c2NHs6thK9yznPF
     July 01, 2002 - Although mortality rates for some groups of women have modestly declined in recent years, 39,600 women … No study found statistically significant differences in mortality between study arms. … Recent trends in mortality rates for four major cancers, by sex and race/ethnicity—United States, 1990 … Recent trends in U.S. breast cancer incidence, survival, and mortality rates. … Do chemopreventive agents reduce mortality from breast cancer?

469. Evidence Summary: Celiac Disease: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/other-supporting-document/celiac-disease-screening
     March 28, 2017 - Does treatment of screen-detected celiac disease lead to improved morbidity, mortality, or quality of … Does treatment of screen-detected celiac disease lead to improved morbidity, mortality, or quality of … Morbidity and mortality among older individuals with undiagnosed celiac disease. … Increased prevalence and mortality in undiagnosed celiac disease. … Does treatment of screen-detected celiac disease lead to improved morbidity, mortality, or quality of

470. Final Research Plan: Unhealthy Drug Use: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/drug-use-illicit-screening
     October 20, 2016 - screening for drug use * in adolescents and adults, including pregnant women, reduce morbidity or mortality … Do counseling interventions to reduce drug use, with or without referral, reduce morbidity or mortality … (e.g., alcohol, tobacco, or other drug use; risky sexual behaviors) KQs 1b, 4b: All-cause mortality … Drug-related mortality (intentional and unintentional) Drug-related morbidity (e.g., mental health … emergency department, hospital inpatient stay) Obstetrical/perinatal/neonatal outcomes (e.g., perinatal mortality

471. Evidence Summary: Peripheral Artery Disease and Cardiovascular Disease: Screening and Risk Assessment With the Ankle-Brachial Index | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/peripheral-artery-disease-in-adults-screening-with-the-ankle-brachial-index
     July 10, 2018 - Main Outcomes and Measures: Cardiovascular morbidity; PAD morbidity; mortality; health-related quality … Observational studies suggest both functional and mortality benefits of statins. 9 , 50-53 An RCT of … , cardiovascular morbidity and mortality, or both at 10 to 15 years of follow-up. … The authors hypothesized that the all-cause mortality benefit was largely seen from preventive measures … The prespecified health outcomes required in this review include CVD and PAD morbidity or mortality or

472. Screening for Chronic Obstructive Pulmonary Disease: USPSTF Recommendation Statement (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/_ZPNC3vqdS3R-ggXro6UAM
     April 05, 2016 - that screening for COPD in asymptomatic persons improves health-related quality of life, morbidity, or mortality … Two studies of LABAs found no difference in all-cause mortality but found decreased exacerbation of COPD … inhaled corticosteroids found decreased exacerbation of COPD symptoms but no difference in all-cause mortality … with corticosteroids and LABAs found decreased exacerbation of COPD symptoms but no differ- ences in mortality … Mortality in the United States, 2013. NCHS Data Brief. 2014; (178):1-8. 2.

473. Recommendation: Thyroid Dysfunction: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/recommendation/thyroid-dysfunction-screening
     March 24, 2015 - hyperthyroidism on final health outcomes, such as fractures, cancer, or cardiovascular morbidity or mortality … Important clinical outcomes include cardiovascular- and cancer-related morbidity and mortality, as well … Impact of subclinical thyroid disorders on coronary heart disease, cardiovascular and all-cause mortality … Review: the association of thyroid dysfunction with all-cause and circulatory mortality: is there a causal … Meta-analysis: subclinical thyroid dysfunction and the risk for coronary heart disease and mortality.

474. Archived: Evidence Summary: Radiation-Induced Breast Cancer and Breast Cancer Death: Breast Cancer: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary-radiation-induced-breast-cancer-and-breast-/breast-cancer-screening-january-2016
     January 11, 2016 - Objective:  To estimate distributions of radiation-induced breast cancer incidence and mortality from … Conclusion: Radiation-induced breast cancer incidence and mortality from digital mammography screening … This approach provided estimates of breast cancer incidence and mortality with and without screening … We also projected breast cancer incidence and mortality with and without screening. … by multiplying radiation-induced breast cancer incidence by the age-specific case–fatality rates of

475. Archived: Evidence Summary: Breast Cancer: Medications for Risk Reduction | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/v1-breast-cancer-medications-for-risk-reduction--s
     May 06, 2002 - Although mortality rates for some groups of women have modestly declined in recent years, 39,600 women … Recent trends in mortality rates for four major cancers, by sex and race/ethnicity--United States, 1990 … Recent trends in U.S. breast cancer incidence, survival, and mortality rates. … Outcome is incidence, mortality, recurrence, or disease-free interval. … Outcome is incidence of or mortality from breast cancer.

476. Archived: Evidence Summary: Breast Cancer: Medications for Risk Reduction | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/breast-cancer-medications-for-risk-reduction-2002
     May 06, 2002 - Although mortality rates for some groups of women have modestly declined in recent years, 39,600 women … Recent trends in mortality rates for four major cancers, by sex and race/ethnicity--United States, 1990 … Recent trends in U.S. breast cancer incidence, survival, and mortality rates. … Outcome is incidence, mortality, recurrence, or disease-free interval. … Outcome is incidence of or mortality from breast cancer.

477. untitled (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/DTQjYT4px77QrDWz3SS5SS
     March 07, 2017 - screening pelvic examinations in asymptomatic women has a significant effect on disease morbidity and mortality … unclear whether performing screening pelvic examinations in asymptomatic women reduces morbidity and mortality … , disease-specific mor- bidity or mortality, or quality of life.4 Harms of Screening The USPSTF found … Some conditions, such as ovar- ian cancer, are associated with a high mortality rate (5-year survival … rate of 46.2%),12 while other conditions, such as candidiasis, have no known associated mortality.

478. Archived: Final Evidence Summary: Gestational Diabetes: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary26/gestational-diabetes-screening1
     May 15, 2008 - Maternal: mortality; preeclampsia/pregnancy-induced hypertension. … Did not address specified conditions and/or mortality. … rates. … Perinatal mortality in Type 2 diabetes mellitus. Diabet Med . 2000;17:33-9. … Gestational diabetes and perinatal mortality rate. Am J Obstet Gynecol . 1973;116:901-4.

479. Archived: Final Evidence Summary: Gestational Diabetes: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary26/gestational-diabetes-screening-2008
     May 15, 2008 - Maternal: mortality; preeclampsia/pregnancy-induced hypertension. … Did not address specified conditions and/or mortality. … rates. … Perinatal mortality in Type 2 diabetes mellitus. Diabet Med . 2000;17:33-9. … Gestational diabetes and perinatal mortality rate. Am J Obstet Gynecol . 1973;116:901-4.

480. Screening for HIV: Systematic Review to Update the 2005 USPSTF Recommendation (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/dvcAbDQWejyK38oxF8qgka
     November 01, 2012 - Outcomes were mortality, AIDS-related events, HIV transmission risk, and long-term (defined as �2 years … Initiating HAART at Different CD4 Cell Counts or Viral Load Thresholds on Progression to AIDS or Mortality … Progression to AIDS/AIDS-Related Events Mortality or Progression to AIDS/AIDS-Related Events Delayed … In all 4 studies, absolute mortality rates were low (2% to 5%) in patients with CD4 counts greater than … The effect of combined antiretroviral therapy on the overall mortality of HIV-infected individuals.