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381. Final Evidence Summary: Hepatitis C Virus Infection in Adolescents and Adults: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/hepatitis-c-screening
     March 02, 2020 - Main Outcomes and Measures: Mortality, morbidity, quality of life, screening and treatment harms, and … An SVR after antiviral therapy was associated with decreased adjusted risk of all-cause mortality (13 … , liver-related mortality, cirrhosis, and hepatocellular carcinoma). … Thirty-one treatment studies (in 28 publications; n = 3848) reported mortality at 12 to 36 weeks after … A sustained virologic response reduces risk of all-cause mortality in patients with hepatitis C.

382. Evidence Summary: Colorectal Cancer: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/colorectal-cancer-screening
     June 15, 2016 - , or all-cause mortality were reviewed for inclusion. … with CRC mortality findings. … Long-term mortality after screening for colorectal cancer. … and all-cause mortality. … Mortality benefit was limited to distal CRC. Fair to poor.

383. Archived: Evidence Summary: Colorectal Cancer: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/colorectal-cancer-screening-june-2016
     June 15, 2016 - , or all-cause mortality were reviewed for inclusion. … with CRC mortality findings. … Long-term mortality after screening for colorectal cancer. … and all-cause mortality. … Mortality benefit was limited to distal CRC. Fair to poor.

384. Evaluating Test Strategies for Colorectal Cancer Screening: A Decision Analysis (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/UPu84CV2CNuxR8kpVU6e3V
     November 01, 2008 - rate 0 Not varied Not varied Hemoccult SENSA Specificity, % 92.5 95.0 90.0 Sensitivity for adenomas … rate 0 Not varied Not varied Fecal immunochemical test Specificity, % 95.0 98.0 92.5 Sensitivity for … rate 0 Not varied Not varied Sigmoidoscopy (within reach) Specificity, % 92.0 Not varied Not varied … rate 1 per 10 000 Not varied Not varied * Data obtained from reference 29. † We assume that small adenomas … rate that is a function of the stage at diagnosis, age at diagnosis (�75 years or �75 years), time since

385. Archived: Evaluating Test Strategies for Colorectal Cancer Screening: A Decision Analysis for the U.S. Preventive Services Task Force: Colorectal Cancer: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/evaluating-test-strategies-for-colorectal-cancer-screening-a-decision-analysis-for-the-us-preventive-services-task-force/colorectal-cancer-screening-2008
     October 15, 2008 - rate that is a function of the stage at diagnosis, age at diagnosis (<75 years, ≥75 years), time since … rate 0 Not varied Not varied Hemoccult SENSA Specificity, % 92.5 95.0 90.0 … rate 0 Not varied Not varied Fecal immunochemical test Specificity, % 95.0 98.0 … rate 0 Not varied Not varied Sigmoidoscopy (within reach) Specificity, % 92.0 … rate 0 Not varied Not varied Colonoscopy (within reach) Specificity, % 90.0 Not

386. Txncztmvpe5Ftseqts6Obm (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/TxnCztmvpE5FtsEqts6oBM
     November 01, 2015 - (33) CV events or mortality Dolan et al, 2005 (33) Gasowski et al, 2008 (37) Ohkubo et al, … (fatal HF, MI, or sudden death) CV mortality CV mortality CV mortality CV mortality MI or stroke, fatal … All-cause mortality All-cause mortality HR (95% CI) 1.11 (0.93–1.31) 1.16 (1.07–1.25) 1.19 (1.13– … Study, Year (Reference) CV events or mortality Fagard et al, 2005 (38) Ohkubo et al, 1998 (39) … (stroke, MI, or CV death) CV mortality Stroke/TIA (first) All-cause mortality (adjusted) HR (95%

387. Final Research Plan: Tobacco Smoking Cessation in Adults, Including Pregnant Women: Behavioral and Pharmacotherapy Interventions | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan88/tobacco-use-in-adults-and-pregnant-women-counseling-and-interventions
     February 18, 2014 - Key Questions to be Systematically Reviewed Do tobacco cessation interventions improve mortality, … underlying population) Outcomes KQ 1: Health and other outcomes Health outcomes: All-cause mortality … Tobacco-related mortality Tobacco-related morbidity (including, but not limited to: cancer … cardiovascular disease, chronic bronchitis, or other respiratory disorders) Perinatal morbidity/mortality

388. Archived: Final Research Plan: Tobacco Smoking Cessation in Adults, Including Pregnant Women: Behavioral and Pharmacotherapy Interventions | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan88/tobacco-use-in-adults-and-pregnant-women-counseling-and-interventions-september-2015
     February 18, 2014 - Do tobacco cessation interventions improve mortality … population) Outcomes KQ 1: Health and other outcomes Health outcomes: All-cause mortality … Tobacco-related mortality Tobacco-related morbidity (including, but not limited to … cardiovascular disease, chronic bronchitis, or other respiratory disorders) Perinatal morbidity/mortality

389. Final Research Plan: Tobacco Smoking Cessation in Adults, Including Pregnant Persons: Interventions | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/tobacco-use-in-adults-and-pregnant-women-counseling-and-interventions
     July 12, 2018 - Do tobacco cessation interventions improve mortality … underlying population) Outcomes KQ 1 (health and other outcomes) Health outcomes: All-cause mortality … Tobacco-related mortality Tobacco-related morbidity (including, but not limited to: cancer, asthma … cardiovascular disease, chronic bronchitis, or other respiratory disorders) Maternal and perinatal morbidity/mortality

390. Archived: Final Evidence Review: Testicular Cancer: Screening February 2004 | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-review95/testicular-cancer-screening-february-2004
     February 15, 2004 - well designed cohort or case control studies reporting demonstrable health outcomes (morbidity and/or mortality … Key Question 1: Does screening for testicular cancer lead to decreased morbidity and mortality … We found no studies that addressed morbidity or mortality benefits of screening for testicular cancer

391. Final Research Plan: Intimate Partner Violence and Caregiver Abuse of Older or Vulnerable Adults: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/intimate-partner-violence-abuse-older-vulnerable-adults
     April 20, 2023 - partner violence (IPV) in adolescents and adults reduce exposure to IPV, physical or mental morbidity, or mortality … How well do interventions reduce exposure to IPV, physical or mental morbidity, or mortality among screen-detected … older and vulnerable adults reduce exposure to abuse and neglect, physical or mental morbidity, or mortality … well do interventions reduce exposure to caregiver abuse and neglect, physical or mental morbidity, or mortality … effects of IPV (e.g., rates of emergency department visits); quality of life and social isolation; and mortality

392. Final Recommendation Statement: Obstructive Sleep Apnea in Adults: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/RecommendationStatementFinal/obstructive-sleep-apnea-in-adults-screening
     November 15, 2022 - as AHI ≥15) was 13% for men and 6% for women. 1 Severe OSA is associated with increased all-cause mortality … ; however, 28 of these trials reported mortality rates at 12 weeks or less, and 25 of these trials reported … Three RCTs assessed mortality over a longer duration, and none found a statistically significant difference … Four trials reported on mortality; however, the duration of reporting was short (1 to 12 weeks) and only … There is inadequate evidence on the effect of treatment of OSA on other health outcomes such as mortality

393. Evidence Summary: Thyroid Dysfunction: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary7/thyroid-dysfunction-screening
     October 28, 2014 - Subclinical Hypothyroidism Cardiovascular Events and Mortality Table 3. … rates. … Subclinical hypothyroidism and the risk of coronary heart disease and mortality. … Subclinical hyperthyroidism and the risk of coronary heart disease and mortality. … Does screening for thyroid dysfunction reduce morbidity and mortality?

394. Evidence Summary: Vitamin D Deficiency in Adults: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/vitamin-d-deficiency-screening
     April 13, 2021 - Main Outcomes and Measures: Mortality, incident fractures, falls, diabetes, cardiovascular events, cancer … Among community-dwelling populations, treatment was not significantly associated with mortality (pooled … For KQ1 and KQ3, studies reporting health outcomes, such as mortality, falls, fractures, incident disease … All-Cause Mortality Twelve RCTs 18 , 19 , 21 , 22 , 25-27 , 35 , 39 , 42-44 reported all-cause mortality … outcomes over 4 months to 3 years; however, none evaluated mortality as a primary study aim.

395. Archived: Final Evidence Review: Ovarian Cancer: Screening, May 2004 | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-review79/ovarian-cancer-screening-2004
     May 15, 2004 - prospective studies that women with early-stage ovarian cancer detected through screening have lower mortality … with mortality outcomes have been completed, although some are currently in progress. … The studies in which these estimates are based were not RCTs of screening, did not report mortality outcomes … Large RCTs of screening with mortality outcomes are currently in progress and will provide more definitive … Estrogen replacement therapy and ovarian cancer mortality in a large prospective study of US women.

396. Final Research Plan: Cervical Cancer: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/cervical-cancer-screening-adults-adolescents
     March 17, 2022 - mode of collection, and interval of testing) on precancer detection, cancer incidence, morbidity, or mortality … Persons who have a cervix (any age), including persons at increased risk for cervical cancer or morbidity/mortality … lesions (i.e., CIN2+, CIN3+) Invasive cervical cancer (squamous cell carcinoma or adenocarcinoma) Mortality

397. Screening for Prostate Cancer: A Review of the Evidence for the U.S. Preventive Services Task Force (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/G9P7o8jDh4J3NnAk6y-SYL
     December 01, 2011 - ; RR, 0.52 [CI, 0.37 to 0.73] for all-cause mortality). … It did not report prostate cancer– specific mortality. … rate of 0.5% in Medicare claimants (60); 3 other large observa- tional studies reported similar findings … Does PSA-based screening decrease prostate cancer–specific or all-cause mortality? … Screening and prostate-cancer mortality in a ran- domized European study.

398. Draft Research Plan: Sexually Transmitted Infections: Behavioral Counseling | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/draft-research-plan/sexually-transmitted-infections
     January 16, 2025 - protective sexual behaviors, or both, reduce sexually transmitted infections (STIs) or related morbidity and mortality … Outcomes KQ 1 (Health outcomes) : STI incidence (based on testing/biologic confirmation) Mortality … STI-related health outcomes, including cancers, reproductive complications, perinatal or neonatal morbidity/mortality

399. Evidence Summary: Obstructive Sleep Apnea in Adults: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/obstructive-sleep-apnea-in-adults-screening
     January 24, 2017 - (eTable 29 in the Supplement); most (29 RCTs) reported mortality rates at 12 weeks or less. … Sleep disturbances and risk of frailty and mortality in older men. … Sleep-disordered breathing and mortality: a prospective cohort study. … Sleep apnea and 20-year follow-up for all-cause mortality, stroke, and cancer incidence and mortality … Single study for all other outcomes (e.g., cancer-related mortality, stroke, CHD).

400. Archived: Evidence Summary: Obstructive Sleep Apnea in Adults: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/obstructive-sleep-apnea-in-adults-screening-january-2017
     January 24, 2017 - (eTable 29 in the Supplement); most (29 RCTs) reported mortality rates at 12 weeks or less. … Sleep disturbances and risk of frailty and mortality in older men. … Sleep-disordered breathing and mortality: a prospective cohort study. … Sleep apnea and 20-year follow-up for all-cause mortality, stroke, and cancer incidence and mortality … Single study for all other outcomes (e.g., cancer-related mortality, stroke, CHD).