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381. Evidence Summary: Cardiovascular Disease: Risk Assessment With Nontraditional Risk Factors | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary--html/cardiovascular-disease-screening-using-nontraditional-risk-assessment
     July 10, 2018 - Main Outcomes and Measures: Cardiovascular events, mortality, risk assessment performance measures ( … This study found no statistically significant difference in myocardial infarction, mortality, or combined … myocardial infarction and mortality at 4 years between the 2 groups; however, the trial did not have … Four such RCTs reported the outcomes of CVD events, mortality, or both. 41 , 42 , 50 , 64 , 73 Two of … Blood cholesterol and vascular mortality by age, sex, and blood pressure: a meta-analysis of individual

382. Archived: Evidence Summary: BRCA-Related Cancer: Risk Assessment, Genetic Counseling, and Genetic Testing | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary17/brca-related-cancer-risk-assessment-genetic-counseling-and-genetic-testing-2013
     December 15, 2013 - and harms of genetic counseling, genetic testing, and interventions to reduce cancer incidence and mortality … mutation carriers, risk-reducing mastectomy decreased breast cancer by 85% to 100% and breast cancer mortality … In this study, salpingo-oophorectomy did not reduce breast cancer- and ovarian cancer-specific mortality … Whether testing for BRCA mutations reduces cause-specific or all-cause mortality and improves quality … The PLCO (Prostate, Lung, Colorectal, and Ovarian) Cancer Screening Trial reported no mortality benefit

383. Screening for Impaired Visual Acuity in Older Adults: Updated Evidence Report and Systematic Review for the USPSTF (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/DCfAJZvNDzSYu7NqLJX2bv
     March 01, 2016 - Does vision screening in asymptomatic older adults result in improved vision, morbidity or mortality, … Mortality outcomes were reported for AREDS severity categories 2, 3, and 4 (n = 3476). … there was no significant decrease in can- cer mortality risk (adjusted RR, 0.84; 95% CI, 0.65-1.08). … , 0.97-1.49 Cancer mortality: aRR, 1.07; 95% CI, 0.83-1.38 Non-CV, noncancer mortality: aRR, 0.94; 95% … /1847); aHR, 0.83; 95% CI, 0.73-0.95 CV mortality: aRR, 0.80; 95% CI, 0.64-0.99 Cancer mortality: aRR

384. Nontraditional Risk Factors in Cardiovascular Disease Risk Assessment: Updated Evidence Report and Systematic Review for the USPSTF (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/_nVeFxDCT9L-_cnDf_V3fK
     July 17, 2018 - MAIN OUTCOMES AND MEASURES Cardiovascular events, mortality, risk assessment performance measures (calibration … 5 Asymptomatic adults without known CVD CVD events (MI, cerebrovascular accident) Mortality Health … This study found no statistically significant difference in myocardial infarction, mortality, or combined … myocardial infarc- tion and mortality at 4 years between the 2 groups; however, the trial did not have … Blood cholesterol and vascular mortality by age, sex, and blood pressure: a meta-analysis of individual

385. Archived: Skin Cancer: Screening and Behavioral Counseling, 1996 | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/recommendation/skin-cancer-screening-behavioral-counseling-1996
     January 01, 1996 - and Asians. 7 In the past two decades, increases of 4%/year in MM incidence and nearly 2%/year in mortality … primary providers in Scotland found a trend toward a reduction in both thick tumors (p < 0.05) and mortality … The authors noted that in Denmark, which has comparable incidence rates, the MM mortality in women rose … If clinician screening does in fact result in detection of significantly thinner MM, mortality might … No studies on the effectiveness of counseling in reducing skin cancer incidence or mortality were found

386. Archived: Hepatitis B Virus Infection: Screening, 2014 | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/recommendation/hepatitis-b-virus-infection-screening-nonpregnant-adolescents-adults-may-2014
     June 18, 2014 - , quality of life, and all-cause mortality) are needed. … The death rate of HBV infection in the United States in 2010 was an estimated 0.5 per 100,000 persons … The highest death rates occurred in persons aged 55 to 64 years; men; and nonwhite, nonblack persons … Compared with non–HBV-related deaths, HBV-associated mortality is approximately 11 times higher among … The increasing burden of mortality from viral hepatitis in the United States between 1999 and 2007.

387. Archived: Final Research Plan: Syphilis Infection in Pregnant Women: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/syphilis-infection-in-pregnancy-screening-september-2018
     August 31, 2017 - including decreased vertical transmission of syphilis and reduced maternal and infant morbidity and mortality … syphilis after implementation of a screening program; stillbirth; maternal or infant morbidity and mortality

388. Screening for Rh (D) Incompatibility: A Brief Evidence Update (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/3d2JBp6qErtFkw4JjCQ-eo
     November 01, 2004 - new, direct evidence that screening for Rh (D) incompatibility leads to reduced maternal morbidity or mortality … addressing the role of screening for Rh (D) incompatibility leading to reductions in maternal morbidity or mortality

389. Archived: Screening for HIV in Pregnant Women: Evidence Summary: Human Immunodeficiency Virus (HIV) Infection: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/screening-for-hiv-in-pregnant-women-evidence-summary/human-immunodeficiency-virus-hiv-infection-screening-2013
     November 15, 2012 - of HIV screening versus no screening in asymptomatic pregnant women on maternal or child morbidity, mortality … effects of antiretroviral regimens in pregnant, HIV-positive women on long-term maternal morbidity, mortality … of HIV screening versus no screening in asymptomatic pregnant women on maternal or child morbidity, mortality … infant nevirapine as well as single-dose nevirapine alone (14% vs. 17%), and a high rate of infant mortality … effects of antiretroviral regimens in pregnant, HIV-positive women on long-term maternal morbidity, mortality

390. Recommendation: Healthy Diet, Physical Activity, and/or Weight Loss to Prevent Cardiovascular Disease in Adults: Behavioral Counseling Interventions | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/draft-update-summary/behavioral-counseling-interventions-promote-healthy-diet-physical-activity-weight-loss-prevent-cardiovascular-disease-adults
     October 27, 2023 - See Current Final Recommendation Statement for Weight Loss to Prevent Obesity-Related Morbidity and Mortality

391. Update on Methods: Insufficient Evidence - Table 6 | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/update-on-methods-insufficient-evidence---table-6
     February 01, 2009 - The potential of effective interventions in adolescents to prevent future morbidity and mortality due

392. Archived: Evidence Summary: Breast Cancer: Medications for Risk Reduction | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary27/breast-cancer-medications-for-risk-reduction-2013
     April 15, 2013 - Neither reduced breast cancer–specific or all-cause mortality rates. … Breast cancer–specific 8 , 24 , 28 , 31 , 50  and all-cause mortality rates 6-8 , 24 , 28 , 31  were … rate than that of those assigned to placebo in RUTH (RR, 1.49 [CI, 1.00 to 2.24]) 7 . … Noninvasive breast cancer incidence and breast cancer–specific and all-cause mortality rates were not … rates in women with breast cancer after 10 versus 5 years of adjuvant therapy 106 .

393. Screening for Hypertension in Adults: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/QaNSteuunshjz-kHPxVvAN
     April 27, 2021 - be modified through lifestyle and pharmacological interventions to reduce cardiovascular events and mortality … MAIN OUTCOMES AND MEASURES Mortality; cardiovascular events; quality of life; sensitivity, specificity … (rate ratio, 0.86 [95% CI, 0.73-1.01]; intervention group, –0.47 per 1000 persons; control group, 0.2 … Health, United States, 2017: With Special Feature on Mortality. … White-coat hypertension is a risk factor for cardiovascular diseases and total mortality.

394. Archived: Final Evidence Review: Ovarian Cancer: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-review78/ovarian-cancer-screening-2012
     April 15, 2012 - Background: Ovarian cancer has the highest mortality … rate of all gynecologic malignancies, and was the fifth leading cause of cancer death among women in … presentation of symptoms; however, the USPSTF also found fair evidence that the potential impact on mortality … provide direct evidence on the benefits of screening ultrasonography or CA-125 testing in terms of mortality … United States Cancer Statistics: 2004 Incidence and Mortality. Atlanta: U.S.

395. 4Nuuvs6Nmztdbgjbg3Elke (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/4NUuvS6nmzTdBgjBg3ELkE
     January 01, 2020 - Decreases in cardiovascular mortality rates in recent de- cades have been attributed, in part, to improvements … rates (8–17), U.S. adults are not meeting recommendations for healthy diet and physical activity (18 … Overall, there was no reduction in CVD events or mortality rates at 6 to 79 months across 4 (3962 participants … However, this review also found a decrease in mortality rates, primarily due to the inclusion of early … Healthy lifestyle behaviors and all-cause mortality among adults in the United States.

396. Archived: Breast and Ovarian Cancer: BRCA Genetic Testing, September 2005 | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/recommendation/breast-and-ovarian-cancer-brca-testing-screening-2005
     September 15, 2005 - oophorectomy decreases the incidence of breast and ovarian cancer; there is inadequate evidence for mortality … Magnetic resonance imaging (MRI) may detect more cases of cancer, but the effect on mortality is not … The effect of this increased detection on morbidity and mortality remains unclear. … No studies have described cancer incidence or mortality outcomes associated with genetic counseling, … Future studies should examine the impact of intensive MRI screening on breast cancer mortality and on

397. Archived: Lung Cancer: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/recommendation/lung-cancer-screening-december-2013
     December 31, 2013 - ) 12 and a reduction in all-cause mortality of 6.7% (95% CI, 1.2% to 13.6%) 4 . … The relative risk for all-cause mortality in the DLCST was 1.46 (95% CI, 0.99 to 2.15). … Annual screening with LDCT provides the greatest benefit in decreasing lung cancer mortality compared … simulate the effects of various screening programs on the mortality rate of a U.S. cohort born in 1950 … Reduced lung-cancer mortality with low-dose computed tomographic screening.

398. Archived: Final Research Plan: Hepatitis B Virus Infection: Screening, 2014 | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan23/hepatitis-b-virus-infection-screening-nonpregnant-adolescents-adults-may-2014
     March 15, 2013 - B virus (HBV) versus no screening in asymptomatic, nonpregnant adolescents and adults on morbidity, mortality … resistance; development of mutations or antibodies to drugs KQs 1, 6, 7, 9 Final outcomes : mortality

399. Screening for Hepatitis C Virus Infection in Adolescents and Adults: US Preventive Services Task Force Recommendation Statement (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/4GH3or2_-oQ7ChXfjCB2ux
     March 02, 2020 - , mortality due to liver disease, cirrhosis, and hepatocellular carcinoma) • Given the accuracy of the … scores after treatment with a DAA regimen compared with baseline scores.1 Trials reporting short-term mortality … (<1 year) found few events and were not designed to detect differences in mortality rates. … (13 studies; pooled hazard ratio [HR], 0.40 [95% CI, 0.28-0.56]), liver mortality (4 stud- ies; pooled … Rising mortality associated with hepatitis C virus in the United States, 2003-2013.

400. Risk Assessment for Cardiovascular Disease With Nontraditional Risk Factors: US Preventive Services Recommendation Statement (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/6cRgd5whkAvSGESSQsrQLR
     January 01, 2020 - to risk factors in existing CVD risk assessment models, leads to reduced incidence of CVD events or mortality … accounting for 1 in 3 deaths each year.1 Although CVD remains a significant cause of morbidity and mortality … , CVD mortality has been decreasing over time in the United States. … Although it remains a major cause of morbidity and mortality, CVD mortality has been decreasing over … The review focused on the health benefits (reduction in CVD events, CVD mortality, and overall mortality