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341. Final Research Plan: Osteoporosis to Prevent Fractures: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/osteoporosis-screening
     November 18, 2021 - Does screening for fracture risk or osteoporosis reduce fractures and fracture-related morbidity and mortality … Administration (FDA)–approved medications on fracture incidence and fracture-related morbidity and mortality … Outcomes KQs 1, 4 (Screening and treatment benefits): All-cause mortality. … Fracture-related mortality.

342. Evidence Summary: Vitamin D, Calcium, or Combined Supplementation for the Primary Prevention of Fractures in Community-Dwelling Adults: Preventive Medication | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/vitamin-d-calcium-or-combined-supplementation-for-the-primary-prevention-of-fractures-in-adults-preventive-medication
     April 17, 2018 - Main Outcomes and Measures: Incident fracture, mortality, kidney stones, cardiovascular events, and … Supplementation with vitamin D alone or with calcium had no significant effect on all-cause mortality … No studies reporting outcomes related to fracture-related morbidity or mortality were identified. … All-Cause Mortality Seven RCTs examined the effect of supplementation with vitamin D alone, 14-18 … calcium alone, 22 or vitamin D with calcium 24 , 25 on all-cause mortality.

343. Sbmxphuqwo-Dc85Fj5Whf (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/_SBmXPhUQWo-dc85FJ5wHf
     February 01, 2015 - Cardiac events or mortality Staessen et al, 1999 (39) Dolan et al, 2005 (41) CV events or mortality … (fatal HF, MI, or sudden death) CV mortality CV mortality CV mortality CV mortality MI or stroke … All-cause mortality All-cause mortality 1.11 (0.93–1.31) 1.16 (1.07–1.25) 1.19 (1.13–1.27) 1.42 … Risk for cardiovascular and mortality outcomes: systolic HBPM, adjusted for OBPM. … , MI, or death) CV mortality Stroke/TIA (first) All-cause mortality (adjusted) 1.17 (1.02–1.33)

344. Use of Decision Models in the Development of Evidence-Based Clinical Preventive Services Recommendations (pdf file)
     www.uspreventiveservicestaskforce.org/uspstf/sites/default/files/inline-files/decision-modeling-for-uspstf_0.pdf
     July 01, 2016 - , total mortality, or quality of life (Figure 1, step 1). … Is there direct evidence that screening reduces morbidity and/or mortality? 2. … Is the intermediate outcome reliably associated with reduced morbidity and/or mortality? 7. … Estimated lung cancer mortality reduction (as percentage of total lung cancer mortality in cohort) from … Aspirin Use in Adults: Cancer, All-Cause Mortality, and Harms.

345. Archived: Cervical Cancer: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/recommendation/cervical-cancer-screening-2012
     March 15, 2012 - The current annual incidence rate is 6.6 cases per 100,000 women, and the age-adjusted mortality rate … The reduction of mortality and morbidity associated with the introduction of cytology-based screening … every 3 years starting at 15 years of age, 18 years of age, and 21 years of age finds cervical cancer death … rates of 1.54, 1.54, and 1.55 per 1000 women, respectively 4 . … Efforts to further reduce the burden of cervical cancer mortality can be best achieved by focusing on

346. Recommendation: Weight Loss to Prevent Obesity-Related Morbidity and Mortality in Adults: Behavioral Interventions | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/recommendation/obesity-in-adults-interventions
     September 18, 2018 - Final Recommendation Statement Weight Loss to Prevent Obesity-Related Morbidity and Mortality … There were no significant differences in mortality between intervention and control groups (4 trials … Losing weight may reduce the risk for illness and mortality and improve overall health. … Association of all-cause mortality with overweight and obesity using standard body mass index categories … Body-mass index and cause-specific mortality in 900,000 adults: collaborative analyses of 57 prospective

347. Archived: Problem Drinking: Screening, 1996 | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/recommendation/problem-drinking-screening-1996
     January 01, 1996 - rates are 20-40% lower in men and women who drink 1-2 drinks/day than in nondrinkers. 15 , 21 , 22 … Alcohol and mortality. Ann Intern Med . 1992;117:646–654. [ PubMed ] 12. … Alcohol-related mortality and years of potential life lost—United States, 1987. … Risk of cardiovascular mortality in alcohol drinkers, ex-drinkers and non-drinkers. … The relationship between mortality and intensity of inpatient alcoholism treatment.

348. Archived: Final Research Plan: Child Maltreatment: Interventions | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/child-maltreatment-primary-care-interventions-november-2018
     August 18, 2016 - exposure to abuse and neglect; improved behavioral, emotional, physical, and mental well-being; or reduced mortality … exposure to abuse or neglect; improve behavioral, emotional, physical, or mental well-being; or reduce mortality … attendance and performance Reduced risky behaviors and outcomes (e.g., sexually transmitted diseases) Mortality

349. Final Research Plan: BRCA-Related Cancer: Risk Assessment, Genetic Counseling, and Genetic Testing | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/brca-related-cancer-risk-assessment-genetic-counseling-testing
     April 11, 2024 - counseling, and genetic testing reduce the incidence of BRCA-related cancer and cause-specific and all-cause mortality … with pathogenic BRCA1/2 mutations, do interventions reduce the incidence of BRCA-related cancer and mortality … comparisons Outcomes KQs 1, 4: Incidence of BRCA1/2 -related cancer; disease-specific and all-cause mortality

350. Archived: Evidence Summary: Alcohol Misuse: Screening and Behavioral Counseling Interventions in Primary Care | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary9/alcohol-misuse-screening-and-behavioral-counseling-interventions-in-primary-care-2013
     September 25, 2012 - A meta-analysis examining the association between all-cause mortality and average alcohol consumption … rates 79 ). … Meta-analysis of alcohol and all-cause mortality: a validation of NHMRC recommendations. … Rate ratio, 0.64 (95% CI, 0.24 to 1.7); 4 trials; 2006 participants † Low Insufficient 1 death … (rate ratio, 0.52 [CI, 0.22 to 1.2]; 6 trials; 2255 participants), although point estimates trended

351. Evidence Summary: Hepatitis B Virus Infection in Adolescents and Adults: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/hepatitis-b-virus-infection-screening
     December 15, 2020 - Clinical outcomes were mortality or morbidity (cirrhosis, hepatocellular cancer, quality of life, HBV … in 4 trials, 17 , 22 , 23 , 25 and 8 deaths in 3 trials 23 , 25 , 31 (2 other trials that reported mortality … Antiviral therapy was associated with decreased risk of mortality vs placebo or no therapy (3 trials, … The composite clinical outcomes consisted of various combinations of mortality, hepatocellular carcinoma … Although antiviral therapy was associated with decreased risk of mortality, the estimate was based on

352. 3W8Wr9Wwayaqujwmjo Bl- (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/3w8Wr9wwAyAqUJWmJo_bL-
     February 01, 2014 - and harms of genetic counseling, genetic testing, and interventions to reduce cancer incidence and mortality … mutation car- riers, risk-reducing mastectomy decreased breast cancer by 85% to 100% and breast cancer mortality … The PLCO (Prostate, Lung, Colorectal, and Ovarian) Cancer Screening Trial reported no mortality benefit … Association of risk-reducing surgery in BRCA1 or BRCA2 mutation carriers with cancer risk and mortality … Effect of screening on ovarian cancer mortality: the Pros- tate, Lung, Colorectal and Ovarian (PLCO)

353. Archived: Final Evidence Summary: Vitamin D and Calcium to Prevent Fractures: Preventive Medication | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary52/vitamin-d-and-calcium-to-prevent-fractures-preventive-medication-2013
     December 10, 2011 - The hazard or risk ratios for the incidence and mortality of colorectal, breast, or total cancer ranged … Serum 25-hydroxyvitamin D, parathyroid hormone, and mortality in older men. … Serum 25-hydroxyvitamin D and cancer mortality in the NHANES III study (1988-2006). … Plasma vitamin D and mortality in older men: a community-based prospective cohort study. … Prospective study of serum vitamin D and cancer mortality in the United States.

354. Archived: Final Research Plan: Falls Prevention in Community-Dwelling Older Adults: Interventions | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/falls-prevention-in-older-adults-interventions-2018
     October 22, 2015 - prevention interventions and the impact of those interventions on falls, falls-related morbidity, and mortality … combination, reduce falls or falls-related injury, improve quality of life, reduce disability, or reduce mortality … education via written materials, video, lecture), usual care   Outcomes KQ 1: Falls Mortality

355. Nfp93-Hva3Bvxkvkbsttgm (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/nfP93-Hva3bvxkvkBStTgm
     after implementation of a screening program, stillbirth, and maternal or infant morbidity and mortality … after implementation of a screening program, stillbirth, and maternal or infant morbidity and mortality … after implementation of a screening program, stillbirth, and maternal or infant morbidity and mortality

356. Behavioral Counseling Interventions to Promote a Healthy Diet and Physical Activity for Cardiovascular Disease Prevention (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/LVS3Mt54D_mBu3MvB5dZVn
     July 01, 2022 - guidelines for a healthy diet and physical activity have lower rates of cardiovascular morbidity and mortality … • Behavioral weight loss interventions to prevent obesity-related morbidity and mortality in adults

357. Final Research Plan: Hepatitis B Virus Infection in Adolescents and Adults: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/hepatitis-b-virus-infection-screening
     March 14, 2019 - of HBsAg clearance (Key Question 4), and a second arrow leads to clinical health outcomes, including mortality … hepatitis B virus (HBV) infection in asymptomatic, nonpregnant adolescents and adults on morbidity, mortality … result of antiviral therapy vs. no effects on intermediate outcome   Outcomes KQs 1, 5, 7: Mortality

358. Ced9Pf3Pnuhruptzxqza-N (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/cED9Pf3PNUHRUptzXQza-n
     April 01, 2016 - Radiation-Induced Breast Cancer Incidence and Mortality From Digital Mammography Screening A Modeling … Objective: To estimate distributions of radiation-induced breast cancer incidence and mortality from … Conclusion: Radiation-induced breast cancer incidence and mortality from digital mammography screening … We also projected breast cancer inci- dence and mortality with and without screening. … incidence by the age-specific case–fatality rates of non–radiation- induced breast cancer derived from

359. Archived: Drug Use, Illicit: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/recommendation/drug-use-illicit-screening-january-2008
     January 15, 2008 - reducing illicit drug use in the short term,  the longer-term effects of treatment on morbidity and mortality … Mortality among injection drug users is high due to overdose and medical complications (e.g., HIV, hepatitis … There is limited evidence that treatment has a direct effect on long-term morbidity and mortality. … history of treatment, between stopping opiate (usually heroin) misuse and long-term improvement in mortality … rates.

360. Screening For Illicit Drug Use: Recommendation Statement (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/Qh7NQD6ZEynjyRso7L5-gS
     January 15, 2008 - reducing illicit drug use in the short term, the longer-term effects of treatment on morbidity and mortality … effect of treatment on social/legal problems and longer-term health outcomes, including morbidity/mortality … Mortality among injection drug users is high due 4 to overdose and medical complications (e.g., … There is limited evidence that treatment has a direct effect on long-term morbidity and mortality. … rates. 6 Potential harms of screening and treatment: The USPSTF found no evidence of harms