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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan-aspirin-to-prevent-cancer/aspirin-to-prevent-cardiovascular-disease-and-cancer-april-2016
October 07, 2013 - The figure illustrates how aspirin chemoprevention may influence mortality outcomes (KQ 1) in adults … intervention may affect intermediate outcomes, including cancer incidence (KQ 2), colorectal cancer mortality … or all-cause mortality in adults who take (or are eligible for taking) aspirin for the primary prevention … Does regular aspirin use reduce colorectal cancer mortality in adults without a history of colorectal … cancer mortality
Colorectal adenoma incidence
Advanced adenoma incidence
Advanced neoplasia
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www.uspreventiveservicestaskforce.org/uspstf/document/addendum-to-screening-for-ovarian-cancer-evidence-update-for-the-us-preventive-services-task-force-reaffirmation-recommendation-statement/ovarian-cancer-screening-2012
April 15, 2012 - in detection of ovarian cancer at an earlier stage, there also was fair evidence that the impact on mortality … Prior to publishing its mortality results, the PLCO Trial published findings from its first four rounds … Mortality results were planned for a separate publication, although they do not appear to be available … Given the limited data from randomized trials on ovarian cancer screening, it is hoped that the mortality … Effect of screening on ovarian cancer mortality: the Prostate, Lung, Colorectal and Ovarian (PLCO) Cancer
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/asymptomatic-bacteriuria-adults-screening-1996
January 01, 1996 - urinary tract infection is the most common cause of bacteremia, which may be associated with a 10-30% case … fatality rate. 3 , 4 Most such bacteremia occurs in residents with indwelling catheters or urinary … rates were 16.4% and 4.9%, respectively, without treatment, compared to 7.9% and 3.2%, respectively, … Bacteriuria and mortality in an elderly population. … Does asymptomatic bacteriuria predict mortality and does antimicrobial treatment reduce mortality in
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/Vc8SLesU493dFQmMKadxGL
December 01, 2003 - The
postoperative mortality rate for these procedures
is 0.2%. … There are no strong data to
demonstrate that weight loss reduces mortality. … Mortality and optimal body mass index in
a sample of the US population. … Body-mass index and mortality in a
prospective cohort of U.S. adults. … Adiposity
and mortality in men. Am J Epidemiol.
2000;152(3):264–271.
21.
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/chronic-obstructive-pulmonary-disease-screening1
October 08, 2020 - obstructive pulmonary disease (COPD) improve health-related quality of life or reduce morbidity or mortality … screen-detected or mild to moderate COPD improve health-related quality of life or reduce morbidity or mortality … Usual care; placebo; no screening/treatment
Active comparator
Outcomes
KQs 1, 2: All-cause mortality … , disease-specific mortality, and COPD-related morbidity; HRQoL at ≥6 months followup
KQ 3: Serious
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/chronic-obstructive-pulmonary-disease-screening
October 08, 2020 - obstructive pulmonary disease (COPD) improve health-related quality of life or reduce morbidity or mortality … screen-detected or mild to moderate COPD improve health-related quality of life or reduce morbidity or mortality … Usual care; placebo; no screening/treatment
Active comparator
Outcomes
KQs 1, 2: All-cause mortality … , disease-specific mortality, and COPD-related morbidity; HRQoL at ≥6 months followup
KQ 3: Serious
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/4zmYnqJXLv8g4LzLrrDDrm
December 01, 2014 - Low-Dose Aspirin Use for the Prevention of Morbidity and Mortality
From Preeclampsia: U.S. … Low-dose aspirin use for the prevention of morbidity and mortality from preeclampsia: clinical summary … LOW-DOSE ASPIRIN USE FOR THE PREVENTION OF MORBIDITY AND MORTALITY
FROM PREECLAMPSIA
CLINICAL SUMMARY … There are racial/ethnic disparities in the prevalence of
and mortality from preeclampsia. … There was no statistically significant reduction
in perinatal mortality (pooled RR, 0.81 [CI, 0.65 to
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/obesity-in-adults-interventions
March 31, 2016 - Print
Final Research Plan
Weight Loss to Prevent Obesity-Related Morbidity and Mortality … weight loss maintenance may result in improved health outcomes, including obesity-related morbidity and mortality … Does the predictive value of body mass index (BMI) for future mortality and health risks differ by specific … primary care–feasible assessment of central adiposity increase the predictive value of BMI for future mortality … What health effects (i.e., mortality and incidence of cardiovascular disease, type 2 diabetes mellitus
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www.uspreventiveservicestaskforce.org/uspstf/document/draft-research-plan/screening-atrial-fibrillation
March 26, 2020 - atrial fibrillation (AF) with electrocardiography (ECG) improve health outcomes (i.e., reduce all-cause mortality … or reduce morbidity or mortality from stroke) in asymptomatic older adults? … , stroke, and stroke-related morbidity or mortality KQ 2: Comparative diagnostic yield (i.e., number … e.g., subsequent ablation with complications), frequency of findings other than AF KQ 5: All-cause mortality … , cardioembolic stroke, and cardioembolic stroke–related morbidity or mortality KQ 6: Any harms requiring
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www.uspreventiveservicestaskforce.org/uspstf/document/draft-research-plan/atrial-fibrillation-with-ecg
March 26, 2020 - atrial fibrillation (AF) with electrocardiography (ECG) improve health outcomes (i.e., reduce all-cause mortality … or reduce morbidity or mortality from stroke) in asymptomatic older adults? … , stroke, and stroke-related morbidity or mortality KQ 2: Comparative diagnostic yield (i.e., number … e.g., subsequent ablation with complications), frequency of findings other than AF KQ 5: All-cause mortality … , cardioembolic stroke, and cardioembolic stroke–related morbidity or mortality KQ 6: Any harms requiring
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/4_pXjq7Egjwb_vjZZT-NGB
May 01, 2021 - Pregnancy Mortality Surveillance System.
Centers for Disease Control and Prevention. … Accessed January 17, 2023. https://www.cdc.gov/
reproductivehealth/maternal-mortality/pregnancy-
mortality-surveillance-system.htm … Reducing disparities in severe
maternal morbidity and mortality. … Racial/ethnic inequities in pregnancy-related
morbidity and mortality. … Maternal
mortality among American Indian/Alaska Native
women: a scoping review.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/ocULFVqnfy4STqcU2DuPzU
May 18, 2021 - Included studies needed
to report outcomes of CRC incidence, CRC-specific mortality, or all-
cause mortality … rate was lower in people who self-
reported at least 1 screening colonoscopy compared with those who … Long-term mortality after screening for colorectal
cancer. … Long-term
colorectal-cancer incidence and mortality after
lower endoscopy. … Reducing
mortality from colorectal cancer by screening for
fecal occult blood.
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/pancreatic-cancer-screening
August 06, 2019 - However, the death rate is 11.0 deaths per 100,000 person-years because the prognosis of pancreatic cancer … , or all-cause mortality. … rate. 36
Estimate of Magnitude of Net Benefit
The USPSTF considered the evidence using a reaffirmation … Perioperative mortality for pancreatectomy; a national perspective. … The 90-day mortality after pancreatectomy is double the 30-day mortality: more than 20,000 resections
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/X--G2-2BHMVFkywKRV6tzC
August 24, 2021 - ,
diabetes-related mortality, and risk of myocardial infarction after 10 to
20 years of intervention … Neither trial found a reduction in all-cause or
type-specific mortality with screening compared with … and CVD-related
mortality in the combined intervention groups vs control group at
23 and 30 years … The UKPDS found that all-cause mortality, diabe-
tes-related mortality, and myocardial infarction were … Cardiovascular
mortality, all-cause mortality, and diabetes
incidence after lifestyle intervention
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/g2bEcQW6ae_NTFZ9KUxT_t
August 24, 2021 - ,
diabetes-related mortality, and risk of myocardial infarction after 10 to
20 years of intervention … Neither trial found a reduction in all-cause or
type-specific mortality with screening compared with … and CVD-related
mortality in the combined intervention groups vs control group at
23 and 30 years … The UKPDS found that all-cause mortality, diabe-
tes-related mortality, and myocardial infarction were … Cardiovascular
mortality, all-cause mortality, and diabetes
incidence after lifestyle intervention
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary-statins/statin-use-in-adults-preventive-medication
November 13, 2016 - Results were similar when the cardiovascular mortality data reported in the 2010 JUPITER publication … Main Outcomes and Measures: All-cause mortality, CVD-related morbidity or mortality, and harms. … Statin therapy was associated with decreased risk of all-cause mortality (risk ratio [RR], 0.86 [95% … mortality in asymptomatic adults 40 years or older without prior CVD events? … Meta-Analysis: Statins vs Placebo and All-Cause Mortality, Cardiovascular Mortality, and Incident Diabetes
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary-statins/statin-use-in-adults-preventive-medication-november-2016
November 13, 2016 - Results were similar when the cardiovascular mortality data reported in the 2010 JUPITER publication … Main Outcomes and Measures: All-cause mortality, CVD-related morbidity or mortality, and harms. … Statin therapy was associated with decreased risk of all-cause mortality (risk ratio [RR], 0.86 [95% … mortality in asymptomatic adults 40 years or older without prior CVD events? … Meta-Analysis: Statins vs Placebo and All-Cause Mortality, Cardiovascular Mortality, and Incident Diabetes
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www.uspreventiveservicestaskforce.org/uspstf/document/draft-research-plan/iron-deficiency-anemia-during-pregnancy-screening-supplementation
April 07, 2022 - deficiency, iron deficiency anemia status, or both
Outcomes
KQ 1: Maternal health outcomes: Mortality … hematologic indices and ferritin levels; and Caesarean delivery rates Infant health outcomes: Perinatal mortality … iron deficiency anemia status, or both
Outcomes
KQs 1, 3, 5: Maternal health outcomes: Mortality … incidence of iron deficiency; hematologic indices and ferritin levels Infant health outcomes: Perinatal mortality
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/QtuWfedsMmUb_sAuKWdsGg
December 31, 2014 - Thus, screening for ovarian cancer might reduce
mortality by identifying tumors at an earlier, more … No reduction in ovarian cancer
mortality was observed in the intervention group compared with those … Prior to publishing its mortality results, the PLCO Trial published findings from its first four
rounds … Mortality results were planned for a separate
publication, although they do not appear to be available … Effect of screening on ovarian cancer mortality: the
Prostate, Lung, Colorectal and Ovarian (PLCO)
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www.uspreventiveservicestaskforce.org/uspstf/document/draft-research-plan/unhealthy-alcohol-use-adolescents-adults-behavioral-counseling-interventions
February 01, 2024 - Does primary care screening for unhealthy alcohol use in adolescents and adults reduce morbidity or mortality … Do counseling interventions to reduce unhealthy alcohol use reduce morbidity or mortality or improve … Other risky behaviors (e.g., other drug use, risky sexual behaviors)
KQs 1b, 4b:
All-cause mortality … Alcohol-related mortality (intentional and unintentional)
Symptoms and conditions associated with … emergency department and inpatient stays
Obstetrical/perinatal/neonatal outcomes (e.g., perinatal mortality